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Energy and Built Environment 2024年第3期5卷 480-491页

作者： Nivethitha Somu anupama Kowli Department of Electrical Engineering Indian Institute of Technology-BombayMumbaiMaharashtra 400076India

With the existence of several conventional and advanced building thermal energy demand forecast models to improve the energy efficiency of buildings,it is hard to find an appropriate,convenient,and efficient *** based on statistical indexes(MAE,RMSE,MAPE,etc.)that characterize the accuracy of the forecasts do not help in the identification of the efficient building thermal energy demand forecast tool since they do not reflect the efforts entailed in implementation of the forecast model,i.e.,data collection to production/use ***,this work presents a Gini Index based Measurement of Alternatives and Ranking according to COmpromise Solution(GI-MARCOS),a hybrid Multi Attribute Decision Making(MADM)approach for the identification of the most efficient building energy demand forecast ***-MARCOS employs(i)GI based objective weight method:assigns meaningful objective weights to the attributes in four phases(1:pre-processing,2:implementation,3:post-processing,and 4:use phase)thereby avoiding unnecessary biases in the expert’s opinion on weights and applicable to domains where there is a lack of domain expertise,and(ii)MARCOS:provides a robust and reliable ranking of alternatives in a dynamic environment.A case study with three alternatives evaluated over three to six attributes in four phases of implementation(pre-processing,implementation,post-processing and use)reveals that the use of GI-MARCOS improved the accuracy of alternatives MLR and BM by 6%and 13%,***,additional validations state that(i)MLR performs best in Phase 1 and 2,while ANN performs best in Phase 3 and 4 with BM providing a mediocre performance in all four phases,(ii)sensitivity analysis:provides robust ranking with interchange of weights across phases and attributes,and(iii)rank correlation:ranks produce by GI-MARCOS has a high correlation with GRA(0.999),COPRAS(0.9786),and ARAS(0.9775).

关键词： Building energy demand Multi-attribute decision making Objective weights Forecast models Sensitivity analysis

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Egg-associated secretions from the brown planthopper(Nilaparvata lugens)activate rice immune responses

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Insect Science 2024年第4期31卷 1135-1149页

作者： Jing Li Shuai Li Jing Li Xinyang Tan Zhichang Zhao Lei Jiang ary A.Hoffmann Jichao Fang Rui Ji Institute of Plant Protection Jiangsu Academy of Agricultural SciencesJiangsu Key Laboratory for Food and Safety-State Key Laboratory Cultivation Base of Ministry of Science and TechnologyNanjingChina College of Plant Protection Nanjing Agricultural UniversityNanjingChina School of Plant Protection Anhui Agricultural UniversityHefeiChina School of BioSciences Bio21 InstituteUniversity of MelbourneParkvilleVICAustralia Jiangsu Collaborative Innovation Center of Regional Modern Agriculture&Environmental Protection Huaiyin Normal UniversityHuaianJiangsu ProvinceChina

The brown planthopper(BPH,Nilaparvata lugens)is a notorious sap-sucking insect pest that damages rice(Oryza sativa)plants throughout *** BPH feeding,saliva enters rice plant tissues,whereas during oviposition egg-associated secretions(EAS)are deposited in damaged plant *** changes in rice to planthopper salivary effectors have been widely ***,the effects of EAS from planthopper on rice immunity remains largely *** this study,we found that both infestation of rice by gravid BPH female adults and treatment with the EAS elicited a strong and rapid accumulation of jasmonic acid(JA),JA-isoleucine,and hydrogen peroxide in *** enhanced plant defenses not only in rice but also in tobacco,and these impaired the performance of BPH on rice,as well as the performance of aphids and whiteflies on ***-throughput proteome sequencing of EAS led to 110 proteins being identified and 53 proteins with 2 or more unique peptides being *** proteins from BPH EAS were also found in the salivary proteome from herbivores,suggesting potential evolutionary conservation of effector functions across feeding and oviposition;however,others were only identified in EAS,and these are likely specifically related to *** findings point to novel proteins affecting interactions between planthoppers and rice during oviposition,providing an additional source of information for effector studies.

关键词： egg-associated secretion Nilaparvata lugens oviposition plant immunity proteome

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Spatio-Temporal Dynamics of Land Use Units in the Kadzel Sub-Catchment Basin in Diffa, Niger

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Journal of Geographic Information System 2024年第4期16卷 259-275页

作者： Karema ary Madou Kaoulé Moussa Mamoudou Boubacar Amadou Issoufou Abdorhimou Mahamane Ali Faculty of Agronomic Sciences University of Diffa Diffa Niger Faculty of Science and Technology Abdou Moumouni University of Niamey Niamey Niger

Environmental degradation linked to land occupation and use, such as climate change and anthropogenic activities, has led to the modification of the landscape units of the Kadzel sub-watershed. The objective of this study is to analyze the dynamics of land use units in the Kadzel area in Diffa between 1992 and 2022 and to propose a future scenario for sustainable environmental management. The approach used relies on remote sensing and geographic information systems to analyze the dynamics of land use units. Additionally, the Markov Cellular Automata (CA) model was used to predict future land use. The land cover maps were produced from a supervised classification by maximum likelihood based on the true and false color compositions of bands 4/3/2 (TM5), 3/2/1 (ETM+) and 7/5/4 (8 OLI). Ten occupation classes were discriminated. Between 1992 and 2022, there was a decrease in the areas of irrigated crops (4.91% and 2.88%), of shrubby tree steppes (14.31% and 9.48%), field-fallow complexes (22.23% and 10.52%), and degraded areas. Grassy steppes (25.76% and 13.32%). However, this reduction has been beneficial for wastelands, urban areas and bodies of water. Based on predictive modeling, it is predicted that by 2052, urban areas, fallow field complexes and bare soils will constitute the main types of housing units. The regressive trend in natural resources appears to continue into the future with current land use practices.

关键词： Occupation Dynamics Environmental Problems Population Growth Lake Chad and Kadzel Basin

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Corrigendum to'Cancer chemotherapy and beyond:Current status,drug candidates,associated risks and progress in targeted therapeutics'[Genes&Diseases 10(2023)1367-1401]

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Genes & Diseases 2024年第4期11卷 426-427页

作者： Uttpal Anand Abhijit Dey Arvind K.Singh Chandel Rupa Sanyal Amarnath Mishra Devendra Kumar Pandey Valentina De Falco Arun Upadhyay Ramesh Kandimalla anupama chaud.ary Jaspreet Kaur Dhanjal Saikat Dewanjee Jayalakshmi Vallamkondu Jose M.Perez de la Lastra Department of Life Sciences Ben-Gurion University of the NegevBeer-Sheva 84105Israel Department of Life Sciences Presidency UniversityKolkataWest Bengal 700073India Center for Disease Biology and Integrative Medicine Faculty of MedicineThe University of TokyoTokyo 113-0033Japan Department of Botany Bhairab Ganguly College(affliated to West Bengal State University)KolkataWest Bengal 700056India Faculty of Science and Technology Amity Institute of Forensic SciencesAmity University Uttar PradeshNoida 201313India Department of Biotechnology School of Bioengineering and BiosciencesLovely Professional UniversityPhagwaraPunjab 144411India Institute of Endocrinology and Experimental Oncology(IEOS) National Research Council(CNR)Department of Molecular Medicine and Medical Biotechnology(DMMBM)University of Naples FedericoⅡNaples 80131Italy Department of Biochemistry School of Life SciencesCentral University of RajasthanBandar SindariKishangarhAjmerRajasthan 305817India CSiR-indian Institute of Chemical Technology HyderabadTelangana 500007India Department of Biochemistry Kakatiya Medical CollegeWarangalTelangana 506007India Orinin-BioSystems LE-52Lotus Road 4CHD CityKarnalHaryana 132001India Department of Computational Biology Indraprastha Institute of Information Technology Delhi(ⅢT-D)Okhla Industrial EstatePhaseⅢNew Delhi 110020India Advanced Pharmacognosy Research Laboratory Department of Pharmaceutical TechnologyJadavpur UniversityKolkata 700032India Department of Physics National Institute of Technology-WarangalWarangalTelangana 506004India Biotechnology of Macromolecules Research Group Instituto de Productos Naturales y AgrobiologiaIPNA-CSICSan Cristobal de La Laguna 38206TenerifeSpain

In the published article,there was an error in the affiliation information about the first author Uttpal Anand[a].Instead of"Department of Life Sciences,Ben-Gurion University of the Negev,Beer-Sheva 84105,Israel",it should be"CytoGene Research&Development LLP,K-51,UPSIDA Industrial Area,Kursi Road(Lucknow),***,225001,Uttar Pradesh,India".The authors would like to apologize for any inconvenience caused and state that this does not change the scientific conclusions of thearticle inanyway.

关键词： Cancer Cor targeted

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Exploration and insights into the cellular internalization and intracellular fate of amphiphilic polymeric nanocarriers

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Acta Pharmaceutica Sinica B 2021年第4期11卷 903-924页

作者： Samrat Mazumdar Deepak Chitkara anupama Mittal Department of Pharmacy Birla Institute of Technology and Science(BITS-PILANI)Rajasthan 333031India

The benefcial or deleterious effects of nanomedicines emerge from their complex interactions with intracellular pathways and their subcellular ***,the dynamic nature of plasma membrane accounts for the movement of these nanocarriers within the cell towards different organelles thereby not only infuencing their pharmacokinetic and pharmacodynamic properties but also bioavailability,therapeutic effcacy and ***,an in-depth understanding of underlying parameters controlling nanocarrier endocytosis and intracellular fate is *** order to direct nanoparticles towards specifc sub-cellular organelles the physicochemical attributes of nanocarriers can be *** include particle size,shape and surface charge/*** the particle size of nanocarriers below 200 nm contributes to internalization via clathrin and caveolae mediated ***,a moderate negative surface potential confers endolysosomal escape and targeting towards mitochondria,endoplasmic reticulum(ER)and *** review aims to provide an insight into these physicochemical attributes of nanocarriers fabricated using amphiphilic graft copolymers affecting cellular *** principles understood from experimental studies have been extrapolated to draw a general conclusion for the designing of optimized nanoparticulate drug delivery systems and enhanced intracellular uptake via specifc endocytic pathway.

关键词： Amphiphilic Copolymer Nanoparticles Internalization Intracellular fate

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Genetic Enhancement of Indigenous Cowpea with Gamma-Ray Induced Trait Variation

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American Journal of Plant Sciences 2024年第8期15卷 651-676页

作者： Mathurin Tiergnin Dabiré Minimassom Philippe Nikiéma Djibril Yonli Safiatou Sanna Wossoguim Josué Gouba Siébou Palé Hamidou Traoré Joseph T. B. Batieno Varra Prasad Zacharia Stewart Jan B. Middendorf Abhishek Rathore anupama J. Hingane Unit de Formation et de Recherches en Sciences et Technologies Dpartement des Sciences de la Vie et de la Terre Universit Norbert ZONGO Koudougou Burkina Faso Institut de lEnvironnement et de Recherches Agricoles (INERA) Ouagadougou Burkina Faso Department of Agronomy Kansas State University Manhattan USA Center for Agriculture-Led Growth Bureau for Resilience and Food Security United States Agency for International Development United States Agency for International Development Washington DC USA International Maize and Wheat Improvement Center (CIMMYT) ICRISAT Campus Patancheru India Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture Department of Nuclear Sciences and Applications Plant Breeding and Genetics Laboratory International Atomic Energy Agency (IAEA) Seibersdorf Vienna Austria

Production of cowpea (Vigna unguiculata (L.) Walp.), a staple legume crop in Sub-Saharan Africa, faces challenges due to biotic and abiotic constraints. Induced mutagenesis was deployed to create genetic variation in two cowpea varieties (KVX396-4-5-2D and Moussa local). The radio-sensitivity tests led to determe the lethal dose 50 (LD50) corresponding to 230 Gy and 220 Gy for KVX396-4-5-2D and Moussa local varieties, respectively. Dried seeds (M0) of each variety were gamma-ray irradiated with LD50 − 50, LD50 and LD50 + 50. M1 seeds were advanced to generate M2, M3 and M4 mutants using the single-seed-descent method. M4 mutant lines were evaluated in rain-fed conditions using a randomized complete block design to assess phenotypic differences. Data on seven qualitative and eleven quantitative traits were collected. The results indicated that the mutation induced variability in three qualitative traits: in KVX 396-4-5-2D mutant lines, with flower and seed color frequencies at 2.61% and 0.56% respectively, and pod dehiscence at a frequency of 0.24%. While in Moussa local mutants, a pod color changed at a frequency of 17%. ANOVA results revealed significant differences between mutants of both varieties for all quantitative traits, including photosynthetic parameters. Positive correlations were observed between leaf diameter and 100-seed weight, and between branch number and 100-seed weight. Hierarchical clustering revealed three clusters among KVX 396-4-5-2D mutants and six clusters among Moussa local mutants. Early maturity and high foliage were induced traits in Cluster 3 of KVX 396-4-5-2D mutants while high hundred-seed weight was induced in Cluster 6 of Moussa local mutants.

关键词： Cowpea Mutagenesis Gamma Rays Radio-Sensitivity Phenotyping

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Mitochondrial DNA suggests a single maternal origin for the widespread triploid parthenogenetic pest species, Paratanytarsus grimmii, but microsatellite variation shows local endemism

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Insect Science 2013年第3期20卷 345-357页

作者： Melissa Carew Bryant Gagliardi ary A. Hoffmann Victorian Centre of Aquatic Pollution Identification and Management Bio21 Institute The Department of Zoology The University ofMelbourne Parkville Victoria 3010 Austrafia

Parthenogenesis is common among invasive pest species, with many partheno- genetic species also showing polyploidy. Parthenogenetic polyploid species often have multiple hybrid origins and the potential to rapidly spread over vast geographical ar- eas. In this study, we examine patterns of mitochondrial and microsatellite variation in a widespread triploid parthenogenetic chironomid pest species, Paratanytarsus grimmii. Based on samples from five countries, including Australia, England, Germany, Japan, and Canada, we found extremely low mitochondrial diversity （〈0.14%）, with most individuals sharing a common and widespread haplotype. In contrast, microsatellite diversity revealed 41 clonal variants, which were regionally endemic. These findings suggest a single invasive maternal lineage ofP grimmii is likely to have recently spread over a broad geographical range. High levels of genotypic endemism suggest P grimmii populations have remained relatively isolated after an initial spread, with little ongoing migration. This, in part, can be attributed to rapid genetic differentiation via mutations of common clonal genotypes after P. grimmii spread, but multiple polyploidization and subsequent founder events are also likely to be contributing factors.

关键词： invasive microsatellites mitochondrial Paratanytarsus grimmii parthenogenesis triploid

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Comparative studies of critical physiological limits and vulnerability to environmental extremes in small ectotherms:How much environmental control is needed?

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Integrative Zoology 2018年第4期13卷 355-371页

作者： ary A.HOFFMANN Carla M.SGRÒ School of BioSciences Bio21 InstituteThe University of MelbourneMelbourneAustralia School of Biological Sciences Monash UniversityMelbourneAustralia

Researchers and practitioners are increasingly using comparative assessments of critical thermal and physiological limits to assess the relative vulnerability of ectothermic species to extreme thermal and aridity conditions occurring under climate *** most assessments of vulnerability,critical limits are compared across taxa exposed to different environmental and developmental ***,many aspects of vulnerability should ideally be compared when species are exposed to the same environmental conditions,allowing a partitioning of sources of variation such as used in quantitative *** is particularly important when assessing the importance of different types of plasticity to critical limits,using phylogenetic analyses to test for evolutionary constraints,isolating genetic variants that contribute to limits,characterizing evolutionary interactions among traits limiting adaptive responses,and when assessing the role of cross generation ***,vulnerability assessments based on critical thermal/physiological limits also need to take place within a context that is relevant to field conditions,which is not easily provided under controlled environmental conditions where behavior,microhabitat,stress exposure rates and other factors will differ from field *** are ways of reconciling these requirements,such as by taking organisms from controlled environments and then testing their performance under field conditions(or vice versa).While comparisons under controlled environments are challenging for many taxa,assessments of critical thermal limits and vulnerability will always be incomplete unless environmental effects within and across generations are considered,and where the ecological relevance of assays measuring critical limits can be established.

关键词： comparative studies common garden critical limits ectotherms environmental control thermal limits stress resistance

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Advances in the imaging of gastroenteropancreatic neuroendocrine neoplasms

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World Journal of Gastroenterology 2022年第26期28卷 3008-3026页

作者： anupama Ramachandran Kumble Seetharama Madhusudhan Department of Radiodiagnosis and Interventional Radiology All India Institute of Medical SciencesNew Delhi 110029India

Gastroenteropancreatic neuroendocrine neoplasms comprise a heterogeneous group of tumors that differ in their pathogenesis,hormonal syndromes produced,biological behavior and consequently,in their requirement for and/or response to specific chemotherapeutic agents and molecular targeted *** imaging techniques are available for functional and morphological evaluation of these neoplasms and the selection of investigations performed in each patient should be customized to the clinical ***,with the increased availability of cross sectional imaging,these neoplasms are increasingly being detected incidentally in routine radiology *** article is a review of the various imaging modalities currently used in the evaluation of neuroendocrine neoplasms,along with a discussion of the role of advanced imaging techniques and a glimpse into the newer imaging horizons,mostly in the research stage.

关键词： Neuroendocrine tumor Gastroenteropancreatic Intravoxel incoherent motion Diffusion weighted imaging Perfusion imaging Dual energy computed tomography

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Mortality of Australian alpine grasses (Poa spp.) after drought: species differences and ecological patterns

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Journal of Plant Ecology 2012年第2期5卷 121-133页

作者： Philippa C.Griffin ary A.Hoffmann Centre for Environmental Stress and Adaptation Research Department of GeneticsBio21 Institute30 Flemington RoadUniversity of MelbourneParkville 3010VictoriaAustralia

Aims Australian alpine ecosystems currently experience high precipitation in the snow-free season,but they are predicted to experience drier conditions under climate *** observed high mortality of the dominant alpine grasses following drought in *** aims were as follows:to test the involvement of plant-available water(PAW)and other environmental variables in grass mortality in the field;to detect possible species differences in drought response and to link soil moisture to precipitation using soil properties and climate *** The dominant tussock grasses of the Australian alpine zone,Poa hothamensis *** ***,Poa hiemata Vickery and Poa phillipsiana Vickery(Poaceae),all exhibited mortality following drought in the Bogong High Plains,Victoria,Australia in *** was calculated using soil water potential measurements,and past drought occurrence was modelled using climate *** then tested the effects of PAW and soil depth on grass survival both at a large spatial scale spanning the elevational range of the alpine zone and at a smaller *** hothamensis and *** were compared in a common-garden experiment to test drought *** Findings Poa hothamensis survival was predicted by dry-season PAW at the small spatial scale;at the large scale,soil depth and elevation were more important predictors of *** survival,but dry-season PAW predicted *** ***-garden experiments supported field observations that *** is more droughtsensitive than is *** also present a simple polynomial relationship between rainfall and field soil moisture,which predicts that the alpine soils dry below wilting point several times a *** suggest the timing of long rain-free periods may be more important than their duration.

关键词： climate change disturbance drought adaptation grassland

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