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Journal of Central South University 2024年第5期31卷 1385-1397页

作者： SINGH Vikrant BANSAL anuj singla Anil Kumar KUMAR Vijay Sant Longowal Institute of Engineering and Technology Longowal Sangrur 148106India Industrial and Production Engineering Department Dr B R Ambedkar National Institute of TechnologyJalandhar 144011India

本研究采用高速火焰喷涂(HVOF)沉积技术,将碳化钒(VC)和铜镍铬(CuNiCr)复合涂层应用于SS316不锈钢上,以解决不锈钢在海洋环境中的腐蚀问题。在室温环境下,在3.5%氯化钠溶液中进行电化学腐蚀,通过扫描电子显微镜(SEM)和能量色散光谱(EDS... 详细信息

本研究采用高速火焰喷涂(HVOF)沉积技术,将碳化钒(VC)和铜镍铬(CuNiCr)复合涂层应用于SS316不锈钢上,以解决不锈钢在海洋环境中的腐蚀问题。在室温环境下,在3.5%氯化钠溶液中进行电化学腐蚀,通过扫描电子显微镜(SEM)和能量色散光谱(EDS)对有涂层和未覆涂层样品的表面形貌进行检测。结果表明,涂层内由铜(Cu)、镍(Ni)和铬(Cr)组成的金属间黏合剂在氯化钠介质的影响下发生变质,从而导致出现衬底间的局部点蚀现象。有趣的是,在涂层配方中加入碳化钒(VC)显著地增强了表面的耐腐蚀性能,从而阻止了密闭腐蚀凹坑的出现。在不同类的涂层中,加入VC的效果最好,最小的腐蚀速率为72.38×10^(-3)mm/a,相比之下,SS316基底的腐蚀速率最快。

关键词：高速火焰喷涂碳化钒铜镍铬电化学腐蚀氯化钠溶液

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Increased Activity of NK Cells and Plasmacytoid Dendritic Cells in HIV-Exposed Seronegative (ESN) Individuals

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World Journal of AIDS 2012年第1期2卷 6-16页

作者： anuj singla Roland Jacobs Reinhold E. Schmidt Ajay Wanchu Sunil K. Arora Clinic for Immunology and Rheumatology Hannover Medical School Hannover Germany Departments of Immunopathology Post Graduate Institute of Medical Education and Research Chandigarh India Internal Medicine Post Graduate Institute of Medical Education and Research Chandigarh India

The mechanisms involved in resistance to HIV-1 infection, especially the role of innate immune response, have not been thoroughly explored in individuals who are repeatedly exposed to HIV-1, but do not get the infection, termed as Exposed sero-negative or ESN. Frequency and activation state of natural killer (NK) cells and plasmacytoid dendritic cells (pDC) in ESNs from North India were compared with those in recently infected HIV positives (RHIV), chronically infected HIV positives (HIV+) and healthy controls (HC). The activation state of NK cells in terms of cytokine response (IFNγ & TNFα) was significantly higher in ESNs compared to the healthy controls, recently infected HIV+ and chronically infected HIV+. Although the number of circulating pDC in different study groups was not significantly different, yet these cells seem to have significantly higher activation state in terms of IFNα production (ex-vivo in response to CpG ODN) in ESNs when compared with other groups. Increased activation status of NK cells and pDC in Exposed but Seronegative individuals indicates their continuous stimulation with HIV antigens due to regular exposure with infected partners and which might be imparting resistance to viral infection in these individuals.

关键词： HIV Exposed Seronegative Innate Immune Responses NK Cells Plasmacytoid Dendritic Cells

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Surgical treatment of Lenke 5 adolescent idiopathic scoliosis: Comparison of anterior vs posterior approach

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World Journal of Orthopedics 2016年第9期7卷 553-560页

作者： Mark F Abel anuj singla Mark A Feger Lindsay D Sauer Wendy Novicoff Department of Orthopedic Surgery University of Virginia

AIM To compare the posterior vs anterior approaches for fusion of Lenke 5 adolescent idiopathic scoliosis curves,matched for curve magnitude and for the distal level of fixation(dLOF) standardized to the third lumbar vertebrae(L3).METHODS A prospectively collected multicenter database was used for this retrospective comparative study. Our dependent variables included sagittal and coronal radiographic measurements, number of fused vertebrae, estimated blood loss, length of hospitalization and SRS total and individual domain scores at the two-year follow-up. Subject demographics were similar for all group *** t-test was used to compare groups for all analyses at P < *** For all matched cases of Lenke 5 curves, a selective approach was used only 50% of the time in cases undergoing a posterior fusion. When comparing a posterior selective approach to an anterior selective approach,surgeons utilizing a posterior approach fused significantly more levels than surgeons using an anterior approach with no other significant differences in radiographic or SRS outcomes(Ant = 4.8 ± 1.0 levels vs post = 6.1 ± 1.0 levels, P < 0.0001). When the dLOF was standardized to L3, the anterior approached provided significantly greater lumbar Cobb percent correction than the posterior approach(Ant = 69.1% ± 12.6% vs post =54.6% ± 16.4%, P = 0.004), with no other significant radiographic or SRS score differences between *** Surgeons treating Lenke 5c curves with a posterior instrumentation and fusion vs an anterior approach include more motion segments, even with a selective fusion. When controlled for the distal level of fixation,the anterior approach provides greater correction of the thoracolumbar curve.

关键词： Instrumentation Thoracolumbar curve Selective fusion

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Metabolic effects of obesity:A review

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World Journal of Diabetes 2010年第3期1卷 76-88页

作者： Parul singla Animesh Bardoloi anuj A Parkash Department of Biochemistry Lady Hardinge Medical College Department of Biochemistry Pt BD Sharma PGIMSRohtak 124001India

With the many recent advances in the biomedical world,vast changes are taking place in our growing knowledge of the physiological aspects of almost all the tissues and organs of the human *** of the most prevalent topics of discussion is the question of obesity and its effect on the metabolic changes in the human *** original classical role of adipose tissue as an energy storage organ has been greatly *** now know that it is an endocrine organ,producing adipokines like leptin,adiponectin,visfatin,resistin,apelin,etc,which modulate metabolic processes in the *** obesity is associated with an increase in the adipose tissue mass,these hormones may be expected to be produced in increased concentrations and may thus have a significant impact on the macronutrient ***,these adipokines may interact with long term energy modulators like *** though the scientific community has started unravelling the mysteries of the close linkage between obesity,its hormones and their physiological effects,a lot still remains to be *** present discussion makes an attempt to trace the basic modern day concepts of the role of obesity in various metabolic processes.

关键词： Obesity Metabolism Adipokines Leptin Adiponectin Visfatin Apelin Insulin

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