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Acupuncture treatment in gastrointestinal diseases: A systematic review

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World Journal of Gastroenterology 2007年第25期13卷 3417-3424页

作者： antonius Schneider Konrad Streitberger Stefanie Joos University Hospital Heidelberg Department of General Practice and Health Services Research Germany University Hospital Heidelberg Department of Anaesthesiology Germany

The purpose of this work was to assess the evidence for effectiveness of acupuncture （AC） treatment in gastrointestinal diseases. A systematic review of the Medline-cited literature for clinical trials was performed up to May 2006. Controlled trials assessing acupuncture point stimulation for patients with gastrointestinal diseases were considered for inclusion. The search identified 18 relevant trials meeting the inclusion criteria. Two irritable bowel syndrome （IBS） trials, 1 Crohn＇s disease and 1 colitis ulcerosa trial had a robust random controlled trial （RCT） design. In regard to other gastrointestinal disorders, study quality was poor. In all trials, quality of life （QoL） improved significantly independently from the kind of acupuncture, real or sham. Real AC was significantly superior to sham acupuncture with regard to disease activity scores in the Crohn and Colitis trials. Efficacy of acupuncture related to QoL in IBS may be explained by unspecific effects. This is the same for QoL in inflammatory bowel diseases （IBD）, whereas specific acupuncture effects may be found in clinical scores. Further trials for IBDs and in particular for all other gastrointestinal disorders would be necessary to evaluate the efficacy of acupuncture treatment. However, it must be discussed on what terms patients benefit when this harmless and obviously powerful therapy with regard to QoL is demystified by further placebo controlled trials.

关键词： Irritable bowel syndrome Inflammatorybowel disease Gastrointestinal disease Placebo Acupuncture

A review of C_1 chemistry synthesis using yttrium-stabilized zirconia catalyst

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Journal of Rare Earths 2008年第1期26卷 1-6页

作者： antonius Indarto Jae-Wook Choi Hwaung Lee Hyung Keun Song Plasma-Catalyst Chemical Process

C1 chemistry based on synthesis gas, methane, and carbon dioxide offers many routes to industrial chemicals. The reactions related to the synthesis of gas can be classified into direct and indirect approach for making such products, such as acetic acid, dimethyl ether, and alcohol. Catalytic syngas processing is currently done at high temperatures and pressures, conditions that could be unfavorable for the life of the catalyst. Another issue of C1 chemistry is related to the methane-initiated process. It has been known that direct methane conversions are still suffering from low yields and selectivity of products resulting in unprofitable ways to produce products, such as higher hydrocarbons, methanol, and so on. However, many experts and researchers are still trying to find the best method to overcome these barriers, for example, by finding the best catalyst to reduce the high-energy barrier of the reactions and conduct only selective catalyst-surface reactions. The appli- cation of Yttria-Stabilized Zirconia （YSZ） and its combination with other metals for catalyzing purposes are increasing. The existence of an interesting site that acts as oxygen store could be the main reason for it. Moreover, formation of intermediate species on the surface of YSZ also contributes significantly in increasing the production of some specific products. Understanding the phenomena happening inside could be necessary. In this article, the use of YSZ for some C1 chemistry reactions was discussed and reviewed.

关键词： C1 chemistry methane synthesis gas methanol yttria-stabilized zirconia catalyst oxygen storage rare earths

Decomposition of CCl_4 and CHCl_3 on gliding arc plasma

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Journal of Environmental Sciences 2006年第1期18卷 83-89页

作者： antonius Indarto CHOI Jae-wook LEE Hwaung SONG Hyung-keun Korea Institute of Science and Technology Clean Technology Research Center P.O. Box 131 Cheongryang Seoul 130-650 Korea Korea Institute of Science and Technology Clean Technology Research Center P.O. Box 131 Cheongryang Seoul 130-650 Korea.

Decomposition of chlorinated hydrocarbons, CCl4 and CHCl3, in gliding plasma was examined. The effects of initial concentrations, total gas flow rates, and power consumption have been investigated. The conversion result was relatively high. It reached 80% for CCl4 and 97% for CHCl3. Using atmospheric air as the carrier gas, the plasma reaction occurred at exothermic reaction and the main products were CO2, CO, and Cl2. Transformation into CCl4 was also detected for CHCl3 decomposition reaction. The conversion of CCh and CHCl3 were increased with the increasing applied frequency and decreasing total gas flow rate.

关键词： plasma gliding arc CCl4 CHCl3 decomposition reaction

Effect of dynamic light at the coronary care unit on the length of hospital stay and development of delirium： a retrospective cohort study

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Journal of Geriatric Cardiology 2018年第9期15卷 567-573页

作者： Tobias Pustjens antonius MC Schoutens Loes Janssen Wilfred F Heesen Department of Cardiology Division of Cardiology Viecuri Medical Centre Venlo the Netherlands Flux Plus Tilburg the Netherlands Department of Clinical Epidemiology Viecuri Medical Centre Venlo the Netherlands

Background Disturbed circadian rhythm is a potential cause of delirium and is linked to disorganisation of the circadian rhythmicity. Dynamic light （DL） could reset the circadian rhythm by activation of the suprachiasmatic nucleus to prevent delirium. Evidence regarding the effects of light therapy is predominantly focused on psychiatric disorders and circadian rhythm sleep disorders. In this study, we investi- gated the effect of DL on the total hospital length of stay （LOS） and occurrence of delirium in patients admitted to the Coronary Care Unit （CCU）. Methods This was a retrospective cohort study. Patients older than 18 years, who were hospitalized longer than 12 h at the CCU and had a total hospital LOS for at least 24 h, were included. Patients were assigned to a room with DL （n = 369） or regular lighting condi- tions （n = 379）. DL was administered at the CCU by two ceiling-mounted light panels delivering light with a colour temperature between 2700 and 6500 degrees Kelvin. Reported outcome data were： total hospital LOS, delirium incidence, consultation of a geriatrician and the amount of prescripted antipsychotics. Results Between May 2015 and May 2016, data from 748 patients were collected. Baseline charac- teristics, including risk factors provoking delirium, were equal in both groups. Median total hospital LOS in the DL group was 100.5 （70.8-186.0） and 101.0 （73.0-176.4） h in the control group （P = 0.935）. The incidence of delirium in the DL and control group was 5.4% （20/369） and 5.0% （19/379）, respectively （P = 0.802）. No significant differences between the DL and control group were observed in secon- dary endpoints. Subgroup analysis based on age and CCU LOS also showed no differences. Conclusion Our study suggests exposure to DL as an early single approach does not result in a reduction of total hospital LOS or reduced incidence of delirium. When delirium was diagnosed, it was associated with poor hospital outcome.

关键词： Delirium Dynamic light application Length of hospital stay

Methane Conversion Using Dielectric Barrier Discharge: Comparison with Thermal Process and Catalyst Effects

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Journal of Natural Gas Chemistry 2006年第2期15卷 87-92页

作者： antonius Indarto Jae-Wook Choi Hwaung Lee Hyung Keun Song Korea Institute of Science and Technology Clean Technology Research CenterP.O. Box 131CheongryangSeoul 130-650Korea

The direct conversion of methane using a dielectric barrier discharge has been experimentally studied. Experiments with different values of flow rates and discharge voltages have been performed to investigate the effects on the conversion and reaction products both qualitatively and quantitatively. Experimental results indicate that the maximum conversion of methane has been 80% at an input flow rate of 5 ml/min and a discharge voltage of 4 kV. Experimental results also show that the optimum condition has occurred at a high discharge voltage and higher input flow rate. In terms of product distribution, a higher flow rate or shorter residence time can increase the selectivity for higher hydrocarbons. No hydrocarbon product was detected using the thermal method, except hydrogen and carbon. Increasing selectivity for ethane was found when Pt and Ru catalysts presented in the plasma reaction. Hydrogenation of acetylene in the catalyst surface could have been the reason for this phenomenon as the selectivity for acetylene in the products was decreasing.

关键词： plasma dielectric barrier discharge thermal process methane conversion catalyst

Partial Oxidation of Methane with Sol-Gel Fe/Hf/YSZ Catalyst in Dielectric Barrier Discharge: Catalyst Activation by Plasma

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Journal of Rare Earths 2006年第5期24卷 513-518页

作者： antonius Indarto Jae-Wook Choi Hwaung Lee Hyung Keun Song Jelliarko Palgunadi Clean Technology Research Center Korea Institute of Science and Technology KoreaDepartment of Chemical and Biological Engineering Korea University Korea Clean Technology Research Center Korea Institute of Science and Technology Korea Hydrogen Energy Research Center Korea Institute of Science and Technology Korea

A 1% Fe-30% Hf over yttria-stabilized zirconia catalyst in combination with novel plasma-assisted activation techniques for a direct partial oxidation of methane to methanol was tested using dielectric barrier discharge plasma at ambient temperature and atmospheric pressure. However, instead of methanol, the reaction products were dominated by HE, CO, CO2, C2, and H2O. A catalytically activated plasma process increased the production of methanol compared with a noncatalytic plasma process. The maximum selectivity of methanol production was achieved using a catalyst that was treated at higher applied power.

关键词： methane oxidation dielectric barrier discharge catalyst plasma activation rare earths

Vectorcardiographic QRS area as a predictor of response to cardiac resynchronization therapy

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Journal of Geriatric Cardiology 2022年第1期19卷 9-20页

作者： Mohammed A Ghossein antonius MW van Stipdonk Frits W Prinzen Kevin Vernooy Department of Physiology Cardiovascular Research Institute Maastricht(CARIM)Maastricht UniversityMaastrichtThe Netherlands Department of Cardiology Cardiovascular Research Institute Maastricht(CARIM)Maastricht University Medical CenterMaastrichtThe Netherlands Department of Cardiology Radboud University Medical CentreNijmegenThe Netherlands

Cardiac resynchronization therapy(CRT)is a good treatment for heart failure accompanied by ventricular conduction *** ECG criteria in international guidelines seem to be suboptimal to select heart failure patients for *** criteria QRS duration and left bundle branch block(LBBB)QRS morphology insufficiently detect left ventricular activation delay,which is required for benefit from ***,there are various definitions for LBBB,in which each one has a different association with CRT benefit and is prone to subjective *** studies have shown that the objectively measured vectorcardiographic QRS area identifies left ventricular activation delay with higher accuracy than any of the current ECG ***,various studies have consistently shown that a high QRS area prior to CRT predicts both echocardiographic and clinical improvement after *** beneficial relation of QRS area with CRT-outcome was largely independent from QRS morphology,QRS duration,and patient characteristics known to affect CRT-outcome including ischemic etiology and *** top of QRS area prior to CRT,the reduction in QRS area after CRT further improves *** area is easily obtainable from a standard 12-lead ECG though it currently requires off-line *** applicability will be significantly improved when QRS area is automatically determined by ECG equipment.

关键词： ventricular synchronization conduction

Ion Channels at the Nucleus： Electrophysiology Meets the Genome

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Molecular Plant 2010年第4期3卷 642-652页

作者： antonius J.M. Matzkea Thomas M. Weiger Marjori Matzke Gregor Mendel Institute of Molecular Plant Biology Austrian Academy of Sciences Dr. Bohr-Gasse 3 A-1030 Vienna Austria Department of Cell Biology University of Salzburg A-5020 Salzburg Austria

The nuclear envelope is increasingly viewed from an electrophysiological perspective by researchers interested in signal transduction pathways that influence gene transcription and other processes in the nucleus. Here, we describe evidence for ion channels and transporters in the nuclear membranes and for possible ion gating by the nuclear pores. We argue that a systems-level understanding of cellular regulation is likely to require the assimilation of nuclear electrophysiology into molecular and biochemical signaling pathways.

关键词： Ion channel nuclear Ca^+2 signaling nuclear electrophysiology nuclear membrane nuclear pore.

The kinetic studies of direct methane oxidation to methanol in the plasma process

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Chinese Science Bulletin 2008年第18期53卷 2783-2792页

作者： INDARTO antonius CHOI Jae-Wook LEE Hwaung SONG Hyung Keun Department of Chemical and Biochemical Engineering Korea UniversitySeoul 136-701KoreaClean Technology Research Center Korea Institute of Science and Technology Seoul 130-650 Korea Clean Technology Research Center Korea Institute of Science and TechnologySeoul 130-650 Korea Clean Technology Research Center Korea Institute of Science and TechnologySeoul 130-650Korea

The research outlined here includes a study of methanol production from direct methane conversion by means of thermal and plasma method. The kinetic study, derived from thermal-based approach, was carried out to investigate thoroughly the possible intermediate species likely to be presented in the process. A set of plasma experiments was undertaken by using dielectric barrier discharge (DBD), classified as non-thermal plasma, done at atmospheric pressure and room temperature. Plasma proc- ess yields more methanol than thermal process at the same methane conversion rates and methane to oxygen feed ratios. Oxidation reaction of thermal process resulted CO and CO2 as the most dominant products and the selectivity reached 19% and 68%, respectively. Moreover, more CO and less CO2 were produced in plasma process than in thermal process. The selectivity of CO and CO2 by plasma was 47% and 20%, respectively. Ethane (C2H6) was detected as the only higher hydrocarbon with a signifi- cant concentration. The concentration of ethane reached 9% of the total products in plasma process and 17% in thermal process. The maximum selectivity of methanol, the target material of this research, was 12% obtained by plasma method and less than 5% by thermal process. In some certain points, the kinetic model closely matched with the experimental results.

关键词：等离子体热采方法部分氧化甲烷甲醇