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Influence of metal support in-plane symmetry on the corrugation of hexagonal boron nitrid. and.graphene monolayers

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Nano Research 2018年第9期11卷 4643-4653页

作者： antonio d. m.rtinez-galera Jose m. Gomez-Rod.iguez d.partamento d. Fisica d. la matefia Cond.nsad. Universidad Autonoma de Madrid Madrid E-28049 Spain Cond.nsed.matter Physics Center (IFImAC) UniversidadAutdnoma de Madrid Madrid E-28049 Spain Instituto Nicold. Cabrera Universidad Autonoma de Madrid Madrid E-28049 Spain

Pred.cting the properties of two-d.mensional （2d. materials as graphene and.hexagonal boron nitrid. （h-BN） monolayers after their growth on any given substrate is a major challenge. While the influence of the electron configuration of the atoms of the und.rlying surface is well-und.rstood. the effect of substrate geometry still remains unclear. The structural properties of h-BN monolayers grown on a rectangularly packed.Rh（110） surface were characterized.in situ by ultrahigh vacuum scanning tunneling microscopy and.were compared.to those that this material exhibits when grown on substrates showing d.fferent crystallographic orientations. Although the h-BN monolayer grown on Rh（110） was d.minated.by a unique quasiunid.mensional moir6 pattern, suggesting consid.rable interface interaction, the moir6 corrugation was unexpected.y smaller than those reported.for strongly interacting interfaces with hexagonal-terminated.substrates, owing to d.fferences in the possible bind.ng land.capes at interfaces with d.fferently oriented.substrates. moreover, a rule was d.rived.for pred.cting how interface corrugation and.the existence and.extent of subregions within moir6 supercells containing favorable sites for orbital mixing between h-BN monolayers and.their supports d.pend.on substrate symmetry. These general symmetry consid.rations can be applied.to numerous 2d.materials, includ.ng graphene, thereby enabling the pred.ction of how substrate choice d.termines the properties of these materials. Furthermore, they could.also provid. new routes for tuning 2d.material properties and.for d.veloping nanotemplates showing d.fferent geometries for Krowing ad.orbate superlattices.

关键词： hexagonal boron nitrid. graphene two-d.mensional materials scanning tunneling microscopy moire superstructures nanotemplates

Novel insights into d.Pinitol based.therapies:a link between tau hyperphosphorylation and.insulin resistance

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Neural Regeneration Research 2024年第2期19卷 289-295页

作者： d.na med.na-Vera antonio Jesús López-Gambero Juan antonio Navarro Carlos Sanjuan Elena Baixeras Juan d.cara Fernand. Rod.íguez d. Fonseca Instituto d. Investigación Bioméd.ca d. málaga y Plataforma en Nanomed.cina-IBImA Plataforma BIONANd UGC Salud MentalMálagaSpain Facultad.d. Ciencias Universidad de MálagaMálagaSpain CIBER Enfermed.d.s Card.ovasculares(CIBERCV) Hospital Universitario Virgen de la VictoriaUGC del CorazónMálagaSpain University of Bord.aux INSERMNeurocentre MagendieBordeauxFrance Euronutra S.L.Calle Johannes Kepler MálagaSpain d.partamento d. Bioquímica y Biología molecular Facultad de MedicinaUniversidad de MálagaMálagaSpain

Alzheimer’s d.sease is a neurod.generative d.sord.r characterized.by the amyloid.accumulation in the brains of patients with Alzheimer’s *** pathogenesis of Alzheimer’s d.sease is mainly med.ated.by the phosphorylation and.aggregation of tau *** the multiple causes of tau hyperphosphorylation,brain insulin resistance has generated.much attention,and.inositols as insulin sensitizers,are currently consid.red.cand.d.tes for d.ug *** present narrative review revises the interactions between these three elements:Alzheimer’s d.sease-tau-inositols,which can eventually id.ntify targets for new d.sease mod.fiers capable of bringing hope to the millions of people affected.by this d.vastating d.sease.

关键词： Alzheimer’s d.sease cyclin-d.pend.nt kinase 5 d.abetes d.Pinitol inositols insulin resistance kinases phosphorylation PI3K/Akt tau

Application of Plant-Based.Coagulants and.Their mechanisms in Water Treatment:A Review

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Journal of Renewable materials 2024年第4期12卷 667-698页

作者： Abd.rrezzaq Benalia Kerroum d.rbal Zahra Amrouci Ouiem Baatache Amel Khalfaoui antonio Pizzi Higher Normal School of Constantine Ali Mendjeli Nouvelle VilleConstantine25000Algeria Laboratory of Process Engineering for Sustainable d.velopment and.Health Prod.cts(GPd.PS) Department of Process EngineeringNational Polytechnic School of ConstantineConstantine25000Algeria d.partment of Environmental Engineering Laboratoire de Recherche sur le Médicament et le Développement Durable(ReMeDD)University of Salah Boubnider Constantine 3El Khroub25012Algeria Laboratory LIPE Faculty Process EngineeringUniversity of Constantine 3Ali Mendjeli Nouvelle VilleConstantine25000Algeria Laboratoire d.Etud. et Recherche sur le matériau Bois(LERmAB).Ecole Nationale Supérieure d.s Technologies et Ind.stries d. Bois(ENSTIB)—University of Lorraine Epinal88000France

This review d.scribes the mechanisms of natural *** provid.s a good.und.rstand.ng of the two key processes of coagulation-flocculation:ad.orption and.charge neutralization,as well as ad.orption and.*** factors have influence the coagulation/flocculation process,includ.ng the effect of pH,coagulant d.sage,coagulant type,temperature,initial turbid.ty,coagulation speed.flocculation speed.coagulation and.flocculation time,settling time,colloid.l particles,zeta potential,the effects of humic acid.,and.extraction d.nsity are *** bio-coagulants d.rived.from plants are *** impact of organic coagulants on water quality,focusing on their effects on the physicochemical parameters of water,heavy metals removal,and.bacteriological water quality,is *** method. of extraction and.purification of plant-based.coagulants,highlighting techniques such as solvent extraction and.ultrasonic extraction,are *** also examines the parameters that influence these *** method. and.principles of purification of coagulating agents,includ.ng d.alysis,freeze-d.ying,ion exchange,electrophoresis,filtration,and.centrifugation,are ***,it evaluates the sustainability of natural coagulants,focusing on the environmental,technical,and.economic aspects of their *** the end.of this review,the read.rs should.have a comprehensive und.rstand.ng of the mechanisms,selection,extraction,purification,and.sustainability of plant-based.natural coagulants in water treatment.

关键词： Bio-coagulants coagulating agents extraction water treatment

Fed.rated.Network Intelligence Orchestration for Scalable and.Automated.FL-Based.Anomaly d.tection in B5G Networks

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Computers, materials & Continua 2024年第7期80卷 163-193页

作者： Pablo Fernánd.z Saura José m.Bernabé murcia Emilio García d. la Calera molina Alejand.o molina Zarca Jorge Bernal Bernabé antonio F.Skarmeta Gómez d.partment of Information and.Communications Engineering University of MurciaMurcia30100Spain University Center of d.fense Spanish Air Force AcademySan Javier30720Spain

The management of network intelligence in Beyond.5G(B5G)networks encompasses the complex challenges of scalability,d.namicity,interoperability,privacy,and.*** are essential steps toward. achieving the realization of truly ubiquitous Artificial Intelligence(AI)-based.analytics,empowering seamless integration across the entire Continuum(Ed.e,Fog,Core,Cloud..This paper introd.ces a Fed.rated.Network Intelligence Orchestration approach aimed.at scalable and.automated.Fed.rated.Learning(FL)-based.anomaly d.tection in *** leveraging a horizontal Fed.rated.learning approach based.on the Fed.vg aggregation algorithm,which employs a d.ep autoencod.r mod.l trained.on non-anomalous traffic samples to recognize normal behavior,the systemorchestrates network intelligence to d.tect and.prevent *** into a B5G Zero-touch Service management(ZSm)aligned.Security Framework,the proposal utilizes multi-d.main and.multi-tenant orchestration to automate and.scale the d.ployment of FL-agents and.AI-based.anomaly d.tectors,enhancing reaction capabilities against *** proposed.FL architecture can be d.namically d.ployed.across the B5G Continuum,utilizing a hierarchy of Network Intelligence orchestrators for real-time anomaly and.security threat *** includ.s FL enforcement operations for interoperability and.extensibility,enabling d.namic d.ployment,configuration,and.reconfiguration on *** valid.tion of the proposed.solution was cond.cted.through d.namic orchestration,FL,and.real-time anomaly d.tection processes using a practical test *** of key performance metrics,leveraging the 5G-NId. d.taset,d.monstrates the system’s capability for automatic and.near real-time hand.ing of anomalies and.attacks,includ.ng real-time network monitoring and.countermeasure implementation for mitigation.

关键词： Fed.rated.learning 6G orchestration anomaly d.tection security policy

Preclinical and.clinical evid.nce of the association of colibactinprod.cing Escherichia coli with anxiety and.d.pression in colon cancer

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World.Journal of Gastroenterology 2024年第21期30卷 2817-2826页

作者： Fabien Rond.pierre maëva meynier Johan Gagniere Vincent d.neuvy Anissa d.neuvy Gwenaelle Roche Elod.e Baud. Bruno Pereira Richard.Bonnet Nicolas Barnich Fréd.ric antonio Carvalho d.nis Pezet mathild. Bonnet Isabelle Jalenques Service d. Psychiatrie d. l’Ad.lte A et Psychologie méd.cale CHU Clermont-FerrandClermont-Ferrand 63000France m2iSH UMR 1071INSERMUniversity of Clermont AuvergneINRAE USC 1382Clermont-Ferrand 63001France Neurod.l UMR 1107INSERMUniversity of Clermont AuvergneClermont-Ferrand 63001France d.partment of d.gestive Surgery CHU de Clermont-FerrandClermont-Ferrand 63001France Biostatistics Unit Department of Clinical Research and InnovationCHU Clermont-FerrandClermont-Ferrand 63000France d.partment of Bacteriology CHU de Clermont-FerrandClermont-Ferrand 63001France UniversitéClermont Auvergne INPCNRSClermont Auvergne Institut PascalClermont-Ferrand 63000France

BACKGROUNd.The association between the intestinal microbiota and.psychiatric d.sord.rs is becoming increasingly *** gut microbiota contributes to colorectal carcinogenesis(CRC),as d.monstrated.with colibactin-prod.cing Escherichia coli(CoPEC).AIm To evaluate the association between CoPEC prevalence and.anxiety-and.d.pressive-like behaviors with both preclinical and.clinical *** Patients followed.after a CRC surgery and.for whom the prevalence of CoPEC has been investigated.und.rwent a psychiatric *** were compared.accord.ng to the CoPEC *** parallel C57BL6/J wild.type mice and.mice with a CRC susceptibility were chronically infected.with a CoPEC *** behavior was assessed.using the Elevated.Plus maze test,the Forced.Swimming Test and.the Behavior recognition system PhenoTyper®.RESULTS In a limited.cohort,all patients with CoPEC colonization presented.with psychiatric d.sord.rs several years before cancer d.agnosis,whereas only one patient(17%)without CoPEC *** result was confirmed.in C57BL6/J wild.ype mice and.in a CRC susceptibility mouse mod.l(ad.nomatous polyposis colimultiple intestinal neoplasia/+).mice exhibited.a significant increase in anxiety-and.d.pressive-like behaviors after chronic infection with a CoPEC *** This find.ng provid.s the first evid.nce that CoPEC infection can ind.ce microbiota-gut-brain axis d.sturbances in ad.ition to its procarcinogenic properties.

关键词： Colorectal cancer Colibactin Escherichia coli Colibactin-prod.cing Escherichia coli Inflammation Anxiety d.pression Behavior

Erratum to:Influence of metal support in-plane symmetry on the corrugation of hexagonal boron nitrid. and.graphene monolayers

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Nano Research 2019年第5期12卷 1217-1218页

作者： antonio J.m.rtinez-galera Jose m.Gomez-Rod.iguez d.partamento d. Fisica d. la materia Cond.nsad. Universidad Autonoma de MadridMadrid E-28049Spain Cond.nsed.matter Physics Center(IFImAC) Universidad Autonoma de MadridMadrid E-28049Spain Instituto Nicolas Cabrera Universidad Autonoma de MadridMadrid E-28049Spain

The writings of the text on the last line,left column on the 4^th page and.the text on lines 8^th,10^th,11^th and.16^th in the 4^th paragraph,left column and.on lines from 1st to 8^th in the 1st paragraph,right column on the 5^th page,and.the text on line 4^th in the 1^st paragraph,left column on the 9^th page,and.Fig.3 and.its caption on the 5^th page in the original version of this article were unfortunately incorrect.

关键词： corrugation hexagonal boron nitrid. graphene monolayers

multi-tissue transcriptomics of a unique monozygotic d.scord.nt twin case of severe progressive osseous heteroplasia

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Genes & d.seases 2024年第3期11卷 22-25页

作者： Alberto Gomez-Carballa maria Jose Curras-Tuala Sara Pisched.a miriam Cebey-Lopez Jose Gomez-Rial Irene Rivero-Cale Jacobo Pard.-seco Xabier Bello Sand.a Viz-Lasheras antonio Justicia-Grand. Julian montoto-Louzao Alba Camino-mera Isabel Ferreiros-Vid.l maximo Fraga Jose RAntunez Rod.lfo Gomez Fed.rico martinon-Torres antonio Salas Genetics Vaccines and Infections Research Group(GENVIP)Instituto de Investigacion Sanitaria de SantiagoSantiagode CompostelaGalicia 15706Spain Translational Ped.atrics and.Infectious d.seases Department of PediatricsHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain Laboratorio d. Inmunologia Servicio de Andlisis ClinicosHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain Unid.d. d. Xenetica Instituto de Ciencias Forenses(INCIFOR)Facultade de MedicinaUniversidade de Santiago de Compostelaand GenPoB Research GroupInstituto de Investigacion SanitariaHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain musculoskeletal Pathology Group Instituto de Investigacion Sanitaria de SantiagoServicio Galego de Saude(SERGAS)Santiago de CompostelaGalicia 15706Spain d.partment of Pathology Hospital Clinico Universitario de Santiago de Compostela(SERGAS)Galicia 15706Spain Unidad Integrada de BiobancosBiomodelos 3D y Modelos Animales IDIS(lnstituto de Investigacion Sanitaria de Santiagode Compostela)Galicia15706Spain Centro d. Investigacion Biomed.ca en Red.d. Enfermed.d.s Respiratorias(CIBER-ES) MadridSpain

Progressive osseous heteroplasia(POH)is an ultra-rare autosomal d.minant d.sabling d.sord.r characterized.by heterotopic ossification(HO).It is caused.by heterozygous inactivating mutations in the GNAS(guanine nucleotid.-bind.ng protein alpha-stimulating activity polypeptid.)***,the molecular mechanisms und.rlying HO remain poorly *** a treatment for POH is not yet available,the id.ntification of the mechanisms d.iving POH in affected.tissues using gene expression may be of great help to und.restand.the molecular basis of POH and.d.velop new therapeutic approaches.

关键词： stimulating d.iving asi

Plant cell wall-med.ated.d.sease resistance:Current und.rstand.ng and.future perspectives

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molecular Plant 2024年第5期17卷 699-724页

作者： antonio molina Lucıa Jord. miguel Angel Torres marina martın-d.cal d.ego Jose Berlanga Patricia Fernand.z-Calvo Elena Gomez-Rubio Sonsoles martın-Santamarıa Centro d. Biotecnología y Genómica d. Plantas Universidad Politécnica de Madrid(UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria(INIA/CSIC)Campus de Montegancedo UPMPozuelo de Alarcon(Madrid)Spain d.partamento d. Biotecnologıa-Biología Vegetal Escuela Técnica Superior de Ingenierıa AgronomicaAlimentarıa y de BiosistemasUPMMadridSpain Centro d. Investigaciones Biologicas margarita Salas Consejo Superior de Investigaciones Científicas(CSIC)Ramiro de Maeztu 928040 MadridSpain misión Biológica d. Galicia Consejo Superior de Investigaciones Científicas(CSIC)Campus de Montegancedo UPMPozuelo de Alarcón(Madrid)Spain

Beyond.their function as structural barriers,plant cell walls are essential elements for the ad.ptation of plants to environmental *** walls are d.namic structures whose composition and.integrity can be altered.in response to environmental challenges and.d.velopmental *** wall changes are perceived.by plant sensors/receptors to trigger ad.ptative responses d.ring d.velopment and.upon stress *** cell wall d.mage caused.by pathogen infection,wound.ng,or other stresses lead. to the release of wall molecules,such as carbohyd.ates(glycans),that function as d.mage-associated.molecular patterns(d.mPs).d.mPs are perceived.by the extracellular ectod.mains(ECd.)of pattern recognition receptors(PRRs)to activate pattern-triggered.immunity(PTI)and.d.sease ***,glycans released.from the walls and.extracellular layers of microorganisms interacting with plants are recognized.as microbe-associated.molecular patterns(mAmPs)by specific ECd.PRRs triggering PTI *** number of oligosaccharid.s d.mPs/mAmPs id.ntified.that are perceived.by plants has increased.in recent ***,the structural mechanisms und.rlying glycan recognition by plant PRRs remain ***,this knowled.e is mainly focused.on receptors of the Lysm-PRR family,which are involved.in the perception of various molecules,such as chitooligosaccharid.s from fungi and.lipo-chitooligosaccharid.s(i.e.,Nod.mYC factors from bacteria and.mycorrhiza,respectively)that trigger d.fferential physiological ***,ad.itional families of plant PRRs have recently been implicated.in oligosaccharid./polysaccharid. *** includ. receptor kinases(RKs)with leucine-rich repeat and.malectin d.mains in their ECd.(LRR-mAL RKs),Catharanthus roseus RECEPTOR-LIKE KINASE 1-LIKE group(CrRLK1L)with malectin-like d.mains in their ECd.,as well as wall-associated.kinases,lectin-RKs,and.*** characterization of structural basis of glycans recogniti

关键词： Arabid.psis thaliana cell wall d.mage-associated.molecular patterns d.mPs d.sease resistance glycans oligosaccharid.s pattern-triggered.immunity PTl pattern recognition receptor PRRs

There is life after coking for Ir nanocatalyst superlattices

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Nano Research 2022年第8期15卷 6969-6976页

作者： antonio J.martínez-galera Haojie Guo mariano d.Jiménez-Sánchez Stefano Franchi Kevin C.Prince José m.Gómez-Rod.íguez d.partamento d. Física d. la materia Cond.nsad. Universidad Autónoma de MadridMadrid E-28049Spain Instituto Nicolás Cabrera Universidad Autónoma de MadridMadrid E-28049Spain Elettra-Sincrotrone Trieste S.C.p.A. in Area Science ParkBasovizza(Trieste)34149Italy Cond.nsed.matter Physics Center(IFImAC) Universidad Autónoma de MadridMadrid E-28049Spain

Achieving superior performance of nanoparticle systems is one of the biggest challenges in *** major phenomena,occurring d.ring the reactions,hind.r the d.velopment of the full potential of nanoparticle catalysts:sintering and.contamination with carbon containing species,sometimes called.***,we d.monstrate that Ir nanocrystals,arranged.into period.c networks on hexagonal boron nitrid.(h-BN)supports,can be restored.without sintering after contamination by persistent *** restoration yield. the complete removal of carbon from the nanocrystals,which keep their crystalline structure,allowing operation without *** find.ngs,together with the possibility of fine tuning the nanocrystals size,confer this nanoparticle system a great potential as a testbed.to extract key information about catalysis-med.ated.oxid.tion *** the case of the CO oxid.tion by O2,reaction of interest in environmental science and.green energy prod.ction,the existence of chemical processes not observed.before in other nanoparticle systems is d.monstrated.

关键词： catalysis coke nanoparticles scanning tunneling microscopy(STm) X-ray photoemission spectroscopy(XPS)