检索结果-南通市图书馆

Differential distribution of gene polymorphisms associated with hypercholesterolemia,hypertriglyceridemia,and hypoalphalipoproteinemia among Native American and Mestizo Mexicans

引用

World Journal of Hepatology 2022年第7期14卷 1408-1420页

作者： Rafael torres-Valadez Sonia Roman Claudia Ojeda-Granados Karina Gonzalez-Aldaco Arturo Panduro Department of Genomic Medicine in Hepatology Civil Hospital of Guadalajara Fray Antonio Alcalde/Health Sciences CenterUniversity of GuadalajaraGuadalajaraJalisco 44280Mexico Unidad Especializada en Investigación Desarrollo e Innovación en Medicina Genómica Centro Nayarita de Innovación y Transferencia de TecnologíaUniversidad Autónoma de NayaritUnidad Académica de Salud IntegralTepicNayarit 63173Mexico

BACKGROUND Dyslipidemias are metabolic abnormalities associated with chronic diseases caused by genetic and environmental *** Mexican population displays regional differences according to ethnicity with an impact on the type of *** To define the main dyslipidemias,the frequency of lipid-related risk alleles,and their association with hyperlipidemic states among different ethnic groups in West *** In a retrospective study,1324 adults were selected to compare dyslipidemias and lipid-related gene ***,clinical,and laboratory data were collected.A subgroup of 196 normal weight subjects without impaired glucose was selected for the association *** was determined by allelic discrimination *** Hypercholesterolemia was the most prevalent dyslipidemia(42.3%).The frequency of the risk alleles associated with hypoalphalipoproteinemia(ABCA1)and hypercholesterolemia(APOE,LDLR)was higher in the Native Americans(P=0.047).In contrast,the Mestizos with European ancestry showed a higher frequency of the risk alleles for hypertriglyceridemia(APOE2,MTTP)(P=0.045).In normal weight Mestizo subjects,the APOB TT and LDLR GG genotypes were associated risk factors for hypercholesterolemia(OR=5.33,95%CI:1.537-18.502,P=0.008 and OR=3.90,95%CI:1.042-14.583,P=0.043,respectively),and displayed an increase in low-density lipoprotein cholesterol levels(APOB:β=40.39,95%CI:14.415-66.366,P=0.004;LDLR:β=20.77,95%CI:5.763-35.784,P=0.007).CONCLUSION Gene polymorphisms and dyslipidemias showed a differential *** primary health care strategies are required to mitigate their prevalence considering the genetic and environmental features which could have important implications for personalized medicine within the new era of precision medicine.

关键词： Dyslipidemia Ethnicity Genes Obesity Lipids Liver disease Diet

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Aqueous extract of Ocimum tenuiflorum decreases levels of blood glucose in induced hyperglycemic tilapia(Oreochromis niloticus)

引用

Asian Pacific Journal of Tropical Medicine 2012年第8期5卷 634-637页

作者： Amilcar Arenal Leonardo Martín Nestor M Castillo Dainier de la Torre Ubaldo torres Reinaldo Gonzlez Biochemistry Laboratory Department of Morphophysiology University of Camagüey Km 51/2 74650Cuba Biochemistry Laboratory Department of BiochemistryUniversity of HavanaCuba Center for Genetic Engineering and Biotechnology.P.O.Box 387 Camagüey 70100 Policlinic "Julio antonio Mella" CamagüeyCuba Biochemistry Laboratory Department of Morphophysiology University of Camagüey Km 5 1/2 74650Cuba

Objective:To evaluate,in hyperglycemic tilapia[Oreochromis niloticus(***)].the effect of this aqueous extract on blood glucose ***:The hyperglycemia in *** was induced by adding glucose to fish pond *** aqueous extract of Ocimum tenuiflorum (***) was prepared by boiling fresh leaves and the doses of 0,40,80,200 and 400 mg per liter of pond water were ***:The blood sugar concentration for tilapia with hyperglycemic induced was an average of 50%higher than the control *** blood glucose levels in tilapia after the induction of hyperglycemia were higher than the control group for 90 min after the *** treatment with the aqueous extract of *** dropped the serum glucose level of hyperglycemic tilapia until it was similar to that of the control group and was dose ***:The results indicated that *** was endowed with anti-hyperglycemic *** our knowledge,this is the first report on the use of fish as a diabetes model to test natural extracts from plants.

关键词： Ocimum tenuiflorum Fish model Diabetes mellilus Phytotherapy Tilapi

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

SARS-CoV-2:Air pollution highly correlated to the increase in *** case of Guadalajara,Jalisco,Mexico

引用

Infectious Disease Modelling 2023年第2期8卷 445-457页

作者： Elizabeth torres-Anguiano Itzel Sanchez-Lopez Angeles Garduno-Robles Jorge David Rivas-Carrillo Edgar Alfonso Rivera-Leon Sergio Sanchez-Enríquez Luis Fernando Ornelas-Hernandez Fernando Zazueta Leon-Quintero Eduardo Narciso Salazar Leon-Quintero Guillermo Enrique Juarez-Lopez Fernando antonio Sanchez-Zubieta Mariana Ochoa-Bru Abraham Zepeda-Moreno Onkogenetik/Mexicana de Investigacion y Biotectogía S.A.de C.V GuadalajaraJaliscoMexico Unidad de Biología Molecular Investigacion y DiagnosticoHospital San JavierGuadalajaraJaliscoMexico Departamento de Fisiología Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraJaliscoMexico Departamento de Biología Molecular y Genomica Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraJaliscoMexico Departamento de Clínicas Centro Universitario de los AltosUniversidad de GuadalajaraTepatitlan de MorelosJaliscoMexico Departamento de Clínicas Medicas Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraJaliscoMexico Servicio de Hemato-Oncología Pediatrica Hospital Civil de Guadalajara“Dr.Juan I.Menchaca”GuadalajaraJaliscoMexico Hospital Civil de Guadalajara“Fray antonio Alcalde” GuadalajaraJaliscoMexico

Objectives:To determine whether air pollution or changes in SARS-CoV-2 lineages lead to an increase in ***:Descriptive statistics were used to calculate rates of infection(2020-2021).RT ePCR was used to compare viral loads from October 2020 to February *** sequencing(NGS)(n=92)was used to examine and phylogenetically map SARS-CoV-2 lineages.A correlative“air pollution/temperature”index(I)was developed using regression ***_(2.5),PM_(10),O_(3),NO_(2),SO_(2),and CO concentrations were analyzed and compared to the ***:The mortality rate during the last year was~32%.Relative SARS-CoV-2 viral loads increased in December 2020 and January *** revealed that approximately 80%of SARS-CoV-2 linages were B.1.243(33.7%),B1.1.222(11.2%),B.1.1(9%),B.1(7%),B.1.1.159(7%),and B.1.2(7%).Two periods were analyzed,the prehigh-and high-mortality periods and no significant lineage differences or new lineages were *** correlations of air pollution/temperature index values with mortality were found for IPM_(2.5) and IPM_(10).INO_(2).ISO_(2),and ICO but not for O_(3).Using ICO,we developed a model to predict mortality with an estimated variation of~±5 deaths per day.

关键词： Air pollution COVID-19 Guadalajara Mexico SARS-CoV-2 SARS-CoV-2 lineages

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Use of Silicon in Mitigating Ammonium Toxicity in Maize Plants

引用

American Journal of Plant Sciences 2015年第11期6卷 1780-1784页

作者： Cid Naudi Silva Campos Renato de Mello Prado Cassiano Garcia Roque antonio Joao de Lima Neto Luiz Junior Pereira marques Aridênia Peixoto Chaves Claudia Amaral Cruz Department of Soils and Fertilizers Universidade Estadual Paulista/FCAV Jaboticabal Brazil Department of Soils and Fertilizers Universidade Estadual Paulista/FCAV Jaboticabal Brazil Universidade Federal de Mato Grosso do Sul Chapad&atildeo do Sul Brazil Universidade Federal de Viçosa Vi&ccedilosa Brazil Department of Applied Biology and Agriculture Universidade Estadual Paulista/FCAV Jaboticabal Brazil Department of Plant Science Universidade Federal Rural do Semi-árido Mossoró Brazil M.Sc. in Agronomy Natal Brazil

Silicon is a beneficial element that can mitigate abiotic stresses, such as ammonium toxicity. The objective herein was to evaluate the effects of silicon (Si) on mitigating toxicity caused by excess ammonium in maize plants grown in nutrient solution. An experiment was conducted with maize plants (cultivar DKB 390 VT Pro II) grown in a greenhouse in pots (8 L) in a hydroponic system. The treatments were arranged in a 2 × 2 factorial, consisting of two ammonium concentrations (30 and 60 mmol·L-1) in the absence and presence of Si (10 mmol·L-1), arranged in a completely randomized design with six repetitions. At 28 days after applying the treatments the dry mass of shoots and roots was evaluated, along with accumulation of silicon and nitrogen in the shoots. The use of silicon resulted in increases in the studied variables, regardless of ammonium concentrations. Silicon reduced the effect of toxicity caused by ammonium excess in maize plants, resulting in greater growth and dry matter accumulation.

关键词： Zea mays L. Beneficial Element Nitrogen Nutritional Disorder Abiotic Stress

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Estimation of the Foliar Area by Non-Destructive Methods in Two Stages of Growth of Pepper Plants(Capsicum annuum L.)Hybrid Salvador

引用

American Journal of Plant Sciences 2018年第3期9卷 325-338页

作者： Osvaldo Fosado Téllez Emanuel Munoz Munoz antonio torres García Jorge Luis Cue García Eduardo Fidel Héctor Ardisana Rolando León Aguilar Elízabeth Fosado Obregón Facultad de Ingeniería Agronómica Universidad Técnica de ManabíPortoviejoEcuador Instituto de Ciencias Básicas Universidad Técnica de ManabíPortoviejoEcuador Universidad Técnica del Norte IbarraEcuador Departamento de Ingeniería Industrial Universidad de Pinar del RíoPinar del RíoCuba

The present work was aimed to obtain a model for the determination of the leaf area in function of the length and width of the leaves in pepper (Capsicum annuum L.) hybrid Salvador. The research was carried out in nursery conditions at the Experimental Campus La Teodomira, located in the parish of Lodana, Santa Ana, province of Manabí, Ecuador, in 2016, in the stages of initiation of flowering and flowering-fructification. In each phase 100 physiologically mature leaves of different sizes were collected. Leaves were digitalized in a rectangle with known dimensions, which allowed the area to be calculated through the percentage of pixels of different colors. From the determination of the length and maximum width of each leaf and the estimated area through the digitization process, the regression models were obtained, selecting the better fit generated between the leaf area and the product of the length by the maximum width of the leaf (). In the initiation of flowering stage the quadratic model generated the best coefficient of determination (R2 = 0.958), whereas in the flowering-fructification stage the best coefficient of determination was achieved by the cubic model (R2 = 0.955). The practical applicability of other simpler models among the tested ones, which show a high accuracy and sacrifice a low percentage of error, is discussed.

关键词： Image Binarization Regression Analysis Leaf Area

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nitrogen/Ammonium Concentration Response of Vegetable and Flower Crops

引用

Journal of Agricultural Science and Technology(B) 2014年第4期4卷 261-266页

作者： Armando Hemandez-Perez Oscar Gabriel Villegas-torres Martha Lilia Dominguez-Patifio Martha Lilia Dominguez-Patino Hector Sotelo-Nava antonio Rodriguez-Martinez Luis Alonso Valdez-Aguilar Iria Alia-Tejacal Faculty of Agricultural Sciences University Autonomous of the State of Morelos Cuernavaca 62209 Mexico Faculty of Chemical Sciences and Engineering University Autonomous of the State of Morelos Cuernavaca 62209 Mexico EngineeringandAppliedScience Research Center UniversityAutonomous of the State ofMorelos Cuernavaca 62209 Mexico Department of Horticulture University Autonomus Agrarian Antonio Narro Saltillo 25315 Mexico

Nitrogen （N） is the element with the greatest influence on the growth of vegetables and ornamentals, however, form of delivery, either as nitrate （NO3） or ammonium （NH4＋） has different effects on plant development. The NO3 is the main form of N that plants absorb, but when it is the only source of N that has slight effects on root growth, no effects over enzymatic activities, and stimulates the absorption and translocation of cations within the plant. The NH4＋ is the easiest way of assimilation but is highly toxic when the only source or with respect to the concentration of NO3 is too high. To avoid toxicity, the NH4＋ must not exceed 20% of the total N amount in the formulation, however, it is important to consider the species, variety and environmental conditions. The N as supplied also affects the resistance or susceptibility of plants to diseases, but depends on the species and the type of pathogen.

关键词： Nitrate ammonium vegetables ornamental toxicity nutrition.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Physics, chemistry, and Hirshfeld surface analyses of gamma-irradiated thalidomide to evaluate behavior under sterilization doses

引用

Journal of Pharmaceutical Analysis 2018年第3期8卷 194-201页

作者： Valner A.F.S.N.Mussel Max R Ferreira Maria B.E marques Maria I.Yoshida Mariana R.Almeida Bernardo L.Rodrigues Wagner N.Mussel Departamento de Quimica ICExUniversidade Federal de Minas Gerais-UFMGAv.Antonio Carlos 662731270-901 Belo HorizonteMGBrazil CNEN-CDTN Comissao Nacional de Energia Nuclear-Centro de Desenvolvimento da Tecnologia NuclearAv.Antonio Carlos6627 Belo HorizonteMGBrazil

Thalidomide was indicated as a sedative and antiemetic and prescribed for pregnant women. Its tragic teratogenic effects culminated in withdrawal from the market. Since the discovery of its anti-angiogenic and anti-inflammatory actions, thalidomide has been used in the treatment of leprosy and multiple myeloma, which justify studies of its stability. We investigated the effects of irradiation of thalidomide up to 100 kGy （fourfold the usual sterilizing dose for pharmaceutics）. The polymorph of thalidomide was obtained in an isothermal experiment at 270℃. All samples underwent gamma irradiation for specific times. At different doses, decomposition of the pharmaceutical was not observed up to 100 kGy. The observed effect was angle turning between the phthalimide and glutarimide rings modulated by repulsion towards the carbonyl group, leading to a stable energetic configuration, as measured by the equilibrium in the torsion angle after irradiation. The thalidomide molecule has a center of symmetry, so a full turn starting from 57.3° will lead to an identical molecule. Further irradiation will start the process again. Samples irradiated at 30 and 100 kGy have more compact unit cells and a lower volume, which leads to an increase in the intermolecular hydrogen interaction within the unit cell, resulting in higher thermal stability for polymorph α.

关键词： Thalidomide Thermal stability Polymorphs Gamma irradiation Hirshfeld

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Avocado Nutritional Diagnosis （Persea americana Mill.）＂Hass＂, Soil Fertility and Water Quality in Ocuituco, Morelos

引用

Journal of Chemistry and Chemical Engineering 2013年第11期7卷 1068-1073页

作者： Hector Sotelo-Nava Oscar Gabriel Villegas-torres Martha Lilia Dominguez-Patint Elias Hernfindez Castro Agustin Damian Nava antonio Rodrlguez-Martmez Carlos Manuel Acosta-Duran Maria Andrade-Rodriguez Iran Alia-Tej acal Faculty of Agricultural Sciences Universidad Aut6noma del Estado de Morelos Cuernavaca 62209 Mexico Faculty of Chemical Sciences and Engineering Universidad Aut6noma del Estado de Morelos Cuernavaca 62209 Mexico Unit of Agricultural and Environmental Sciences Universidad Autonoma de Guerrero Guerrero 39196 Mexico Engineering and Applied Science Research Center Universidad Autonoma del Estado de Morelos Cuernavaca 62209 Mexico

Morelos is the fourth in area cultivated and production volume of avocado. Of the 13 municipalities where it is farmed, Ocuituco represents 43.51% and Tetela del Volain 27.53%. Despite being one of the main fruit species in Morelos, no information related to the fertility of the soil where it is grown, the quality of water available for irrigation and nutritional status of this important fruit for the state. The study was conducted in the municipality of Ocuituco which identified three agro-habitats taking into account climate, landform, soil type and altitude. In each agro-habitat were carried out soil sampling to determine the physical and chemical characteristics based on the Mexican Official Standard NOM-021-SEMARNAT-2000, the chemical quality of water for irrigation as described by Richards （1954） and crop nutrient status of avocado ＂Hass＂ according to the methodology described by Maldonado （2002）. The soils had different physical and chemical characteristics, as well as the nutritional status of avocado trees in the three agro-habitats. The trees had excessive concentration of CI, Cu and Zn. Indices of optimal percentage deviation expressed different nutritional requirements. The water used for irrigation was of low salinity and sodium content, so it can be used without restrictions.

关键词： Soil fertility water quality nutrients Hass.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Association between Frailty Syndrome and Anemia in Community-Dwelling Elderly

引用

Advances in Aging Research 2019年第5期8卷 75-87页

作者： Elisa Priscila Sousa de Assis Barbara Gazolla de Macêdo Thais Almeida marques da Silva Poliana de Paula Dias Rezende érica Leandro Marciano Vieira antonio Lucio Teixeira Junior Carlos Maurício de Figueiredo Antunes Laboratório de Epidemiologia Programa de Pós-gradua&#231 o Stricto Sensu em Medicina e Biomedicina Instituto de Ensino e Pesquisa da Santa Casa de Belo Horizonte Belo Horizonte Brasil Fundaç o Hospitalar do Estado de Minas Gerais (FHEMIG) Hospital Regional de Barbacena Fisioterapia Respiratória Barbacena Brasil Departamento de Fisioterapia Instituto da Previdência dos Servidores do Estado de Minas Gerais (IPSEMG) Belo Horizonte Brasil Laboratório Interdisciplinar de Investigaç o Médica Faculdade de Medicina Universidade Federal de Minas Gerais (UFMG) Belo Horizonte Brasil Centre of Addiction and Mental Health (CAMH) Toronto Canada

Frailty is an important and complex phenomenon in the fields of geriatrics and gerontology and a highly relevant topic. Frailty syndrome (FS) is a multidimensional clinical condition characterized by loss of physiological and cognitive reserves across multiple organ systems. The Fried frailty phenotype is the main model used to categorize FS. Recent studies have shown an association between anemia, low hemoglobin concentration and frailty. This study aimed to assess the association between FS and anemia in community-dwelling elderly. An observational cross-sectional design was used, with 308 elderly subjects. Most participants were women (78.2%) between 60 and 69 years old (50.6%). The average schooling level was 9.7 years. Anemia was detected in 9.7% of participants. The frequency of frailty, pre-frailty and non-frailty was 8.2, 74.0 and 17.8%, respectively. The multivariate ordinal logistic regression model identified low levels of brain-derived neurotrophic factor (BDNF) (OR = 0.9, 95% CI = 0.9;0.9) as risk factor associated with FS. No significant association was found between frailty and anemia. Moreover, FS may be influenced by low schooling levels, despite the non-significant result obtained in the statistical model. These findings contribute to elucidating other factors associated with FS, especially in community-dwelling elderly.

关键词： Anemia Frailty Elderly

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Detection of Delayed Hypersensitivity to Fonsecaea pedrosoi Metabolic Antigen （Chromomycin）in Healthy People in an Endemic Area

引用

Journal of Life Sciences 2013年第3期7卷 267-275页

作者： Conceiao de Maria Pedrozo e Silva de Azevedo antonio Augusto Moura da Silva Sirlei Garcia marques Oscar Brufia-Romero Gilnara Fontinelle Silval Cecilia Silva de Lima Flaivia Raquel Femandes do Nascimento Maria Aparecida de Resende Stoianoff Department of Medicine Federal University of Maranh6o S6o Luis City 65604010 Maranh6o Brazil Department of Microbiology Federal University of Minas Gerais Belo Horizonte 31270901 Minas Gerais Brazil

The CBM （chromoblastomycosis） is a disease caused by dematiaceous fungi, which has the species Fonsecaea pedrosoi as main agent. This fungus is found in warm and moist climates, characteristically found in the amazonic lands of the region, where its environmental isolation was once described. This research aimed to identify the healthy population exposed to agent F. pedrosoi in four villages located in the Legal Amazon. In order to clarify the risk factors for allergic immune exposure, a survey was conducted by the technique of delayed skin reaction （IDR） with the metabolic antigen （chromomycin） in 449 healthy individuals. The results showed that 14.9% （67 subjects） were IDR positive, with induration 〉 5 mm. Multivariate analysis with logistic regression for risk factors： living in the village of Z6 Pedro （municipality of Bacabeira in the state of Maranhao, Brazil）,

关键词： Fonsecaeapedrosoi chromomycin risk factor.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：