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Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

Cellular & Molecular Immunology 2021年第9期18卷 2128-2139页

作者： Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya Joséantonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado antonio domínguez-petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez E Clinical Unit of Infectious Diseases Microbiology and Preventive MedicineInstitute of Biomedicine of Seville(IBiS)Virgen del Rocío University HospitalCSICUniversity of SevilleSevilleSpain Department of Medical Biochemistry Molecular Biologyand ImmunologySchool of MedicineUniversity of SevilleSevilleSpain Pneumology Service Galicia Sur Health Research Instituto(IIS Galicia Sur)SERGAS-UVigoVigoSpain Infectious Diseases Unit Department of Internal MedicineComplexo HospitalarioUniversitario de VigoIIS Galicia SurSERGAS-UVigoVigoSpain Group of Virology and Pathogenesis Galicia Sur Health Research Institute(IIS Galicia Sur)-Complexo Hospitalario Universitario de VigoSERGAS-UVigoVigoSpain Unit of Infectious Diseases Microbiologyand Preventive MedicineVirgen del Rocío University HospitalSevilleSpain Institute of Biomedicine of Seville(IBiS) Virgen del Rocío University Hospital/CSIC/University of SevilleSevilleSpain Medico-Surgical Unit of Respiratory Diseases Virgen del Rocío University HospitalSevilleSpain Unit of Emergencies Virgen del Rocío University HospitalSevilleSpain Intensive Care Unit Virgen del Rocío University HospitalSevilleSpain Department of Medicine University of SevilleSevilleSpain Cardiology and Cardiovascular Surgery Unit Virgen del Rocío University HospitalSevilleSpain Rheumatology Unit Virgen del Rocío University HospitalSevilleSpain Internal Medicine Unit Virgen del Rocío University HospitalSevilleSpain Digestive and Hepatobiliary Unit Virgen del Rocío University HospitalSevilleSpain Neurology and Clinical Neurophysiology Unit Virgen del Rocío University HospitalSevilleSpain Endocrinology and Nutrition Unit Virgen del Rocío University HospitalSevilleSpain Urology and Nephrology Unit Virgen del Rocío University HospitalSevilleSpain Unit of Clinical Investigation and Clinical Trials Virgen del Rocío University HospitalSevilleSpain

Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity *** cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease *** this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory ***,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 ***,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were *** findings contribute to a better understanding of the immunological sequelae of COVID-19.

关键词： SARS-CoV-2 COVID-19 Dendritic cell Long-COVID

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Nanoscale mapping of optically inaccessible bound-states-in-the-continuum

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Light(Science & Applications) 2022年第2期11卷 188-196页

作者： Zhaogang Dong Zackaria Mahfoud Ramón Paniagua-domínguez Hongtao Wang antonio I.Fernández-domínguez Sergey Gorelik Son Tung Ha Febiana Tjiptoharsono Arseniy I.Kuznetsov Michel Bosman Joel K.W.Yang Institute of Materials Research and Engineering A*STAR(Agency for ScienceTechnology and Research)2 Fusionopolis Way#08-03 Innovis138634 SingaporeSingapore Department of Materials Science and Engineering National University of Singapore9 Engineering Drive 1117575 SingaporeSingapore Singapore University of Technology and Design 8 Somapah Road487372 SingaporeSingapore Departamento de Física Teórica de la Materia Condensada and Condensed Matter Physics Center Universidad Autónoma de Madrid28049 MadridSpain Singapore Institute of Food and Biotechnology Innovation A*STAR(Agency for ScienceTechnology and Research)31 Biopolis Way#01-02 Nanos138669 SingaporeSingapore

Bound-states-in-the-continuum(BIC)is an emerging concept in nanophotonics with potential impact in applications,such as hyperspectral imaging,mirror-less lasing,and nonlinear harmonic *** true BIC modes are nonradiative,they cannot be excited by using propagating light to investigate their optical *** this paper,for the 1st time,we map out the strong near-field localization of the true BIC resonance on arrays of silicon nanoantennas,via electron energy loss spectroscopy with a sub-1-nm electron *** systematically breaking the designed antenna symmetry,emissive quasi-BIC resonances become *** gives a unique experimental tool to determine the coherent interaction length,which we show to require at least six neighboring antenna *** importantly,we demonstrate that quasi-BIC resonances are able to enhance localized light emission via the Purcell effect by at least 60 times,as compared to unpatterned *** work is expected to enable practical applications of designed,ultra-compact BIC antennas such as for the controlled,localized excitation of quantum emitters.

关键词： antenna states mapping

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Potential seed germination-enhancing plant growth-promoting rhizobacteria for restoration of Pinus chiapensis ecosystems

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Journal of Forestry Research 2021年第5期32卷 2143-2153页

作者： Cristina domínguez-Castillo Julia María Alatorre-Cruz Dolores Castañeda-antonio Jose antonio Munive Xianwu Guo Jesús Francisco López-Olguín Luis Ernesto Fuentes-Ramírez Ricardo Carreño-López Centro de Investigaciones en Ciencias Microbiológicas Instituto de CienciasBenemérita Universidad Autónoma de PueblaPueblaMéxico Universidad Autónoma de Querétaro QuerétaroMéxico Centro de Biotecnología Genómica Instituto Politécnico NacionalReynosaTamaulipasMéxico

Rhizosphere soil samples of three Pinus chiapensis sites were analyzed for their physicochemical properties,soil bacteria isolated and screened in vitro for growthpromoting *** isolates that showed promise were identified to five genera Dyella,Luteimonas,Euterobacter,Paraburkholderia and Bacillus based on the sequences of16 S rRNA *** the strains were isolated from nondisturbed *** bacteria significantly decreased germination time and increased sprout *** acetic acid and gibberellin production and phosphate solubilisation were *** indicate that these biochemicals could be essential for *** distribution and suggest the possibility that PGPR inoculation on *** seeds prior to planting could improve germination and possibly seedling development.

关键词： Pinus chiapensis Plant growth-promoting rhizobacteria Dyella Luteimonas Enterobacter

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Comparison of *** oxygen plasma and chemical treatments for surface modifications of Ti6Al4V

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Bio-Design and Manufacturing 2019年第2期2卷 65-75页

作者： María Elena Alemán.domínguez Zaida Ortega antonio N.Benítez Aday Romero.Pérez Ling Wang Ruymán Santana.Farré Francisco Rodríguez.Esparragón Departamento de Ingeniería de Procesos Universidad de Las Palmas de Gran CanariaCampus universitario de Tafira Baja35017 Las Palmas de Gran CanariaSpain Departamento de Ingeniería Mecánica Universidad de Las Palmas de Gran CanariaCampus universitario de Tafira Baja35017 Las Palmas de Gran CanariaSpain State Key Laboratory for Manufacturing System Engineering School of Mechanical EngineeringXi’an Jiaotong UniversityScience and Technology Park of Xi’an Jiaotong UniversityYanta DistrictXi’an City 710054Shaanxi ProvincePeople’s Republic of China Research Unit Dr.Negrín University Hospital35019 Las PalmasCanary IslandsSpain

Different treatments were conducted over Ti6Al4V samples in order to produce a surface modification to increase cell attachment and *** surface treatments evaluated in this study were as follows:etching with sulfuric acid/hydrochloric acid,oxidizing with hydrogen peroxide and low-pressure oxygen plasma *** contrast to other works found in the literature,this research conducts a comparison between different chemical and physical treatments in terms of different assays for surface characterization:X-ray diffraction,scanning electron microscope(SEM),energy-dispersive X-ray spectroscopy,water contact angle,release of vanadium ions and cell viability tests(MTT)of human osteoblasts(hFOB 1.19).Cell morphology over the different substrates was also studied by SEM *** was found that plasma and peroxide treatments increase the O/Ti ratio at the titanium surface and provide an increase in cell *** the other hand,acid etching provides a superhydrophilic surface which is not able to improve the cell attachment of human osteoblasts.

关键词： Surface activation Titanium alloys Surface functionalization Low-pressure plasma

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Effects of a long-term physical exercise program with and without diet on obese boys after six-month detraining

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World Journal of Pediatrics 2014年第1期10卷 38-45页

作者： antonio García-Hermoso Jose M Saavcdra Yolanda Escalante Ana M domíngue Faculty of Sport Sciences AFIDES Research GroupUniversity of ExtremaduraSpain

Background:Most studies on physical fitness and detraining have been conducted on normal-weight *** results indicate that any gains regress to the untrained control values during the detraining ***,therefore,seems necessary to determine how detraining affects the different fitness parameters in obese *** aim of the present study was to evaluate the effects of detraining(6 months)on kinanthropometry and the components of physical fitness after an intervention(31 months)consisting of a program of exercise and/or diet for obese ***:The participants were 18 boys,aged between 8 and 11 years,divided into E and E+D groups according to the program they *** E group followed a physical exercise program(three 90-minute sessions/week),and the E+D group the same physical exercise program plus a low calorie *** fitness was assessed by the European physical fitness test battery including flamingo balance,plate tapping,sit-andreach,standing broad jump,hand-grip strength,sit-ups,bent-arm hang,10×5-metre shuttle run,and 20-metre endurance shuttle *** Kruskal-Wallis test was applied to reveal overall intergroup differences(E and E+D groups),and measurements showing significant differences were further analysed for differences between individual groups by the Mann-Whitney U ***:In both groups,changes were observed in various physical fitness parameters,especially limb speed(E group,P=0.001;E+D group,P=0.002),agility(E group,P<0.001;E+D group,P<0.001),and aerobic fitness(E group,P=0.009;E+D group,P=0.002).Conclusion:Detraining after a long-term intervention based on the combination of exercise program and exercise program plus diet in obese boys does not affect the changes attained during the intervention.

关键词： aerobic fitness agility balance body mass index strength

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Environmental Impact Assessment for an Absorption Heat Transformer

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Open Journal of Applied Sciences 2016年第7期6卷 409-415页

作者： Jorge Avelino domínguez Patiño antonio Rodríguez Martínez Rosenberg Javier Romero Jonathan Ibarra-Bahena Martha Lilia domínguez Patiño FCQeI (Facultad de Ciencias Químicas e Ingeniería) Universidad Autónoma del Estado de Morelos Cuernavaca México CIICAp (Centro de Investigación en Ingeniería y Ciencias Aplicadas) Universidad Autónoma del Estado de Morelos Cuernavaca México

This study presents the environmental impact assessment of an absorption heat transformer designed to recover 1 kW of thermal energy from each 2 kW of waste heat supplies. The net contribution of the heat transformer is a load avoided of 0.665 kg CO2 equivalents;the recovery process avoids 0.729 kg CO2 equivalents and the major contribution to the environment impacts is the pumping process with 0.0437 kg CO2 equivalents for each 1 kWh recovered. The study results show that absorption heat transformer is a good environmental option because it produces useful energy from waste heat and the final result is an environmental impact diminution.

关键词： Environmental Impact Life Cycle Assessment LCA Absorption Heat Transformer Waste Heat Recovery

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Renal Anastomosing Hemangioma Simulating Angiosarcoma as a Second Primary in a Patient with Breast Cancer

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Open Journal of Urology 2021年第12期11卷 466-473页

作者： Daniel Fernando Méndez López Jhonatan Gómez domínguez Jorge antonio Rojas González Marco antonio Ortiz Jiménez Omar Santos Moreno Department of Radiology in the Governmental Hospital “Hospital de Especialidades 5 de Mayo” (ISSSTEP) Puebla Mexico

Anastomosing hemangioma is a type of tumor lesion of benign behavior scarcely documented, it has been observed in renal parenchyma, testicles, ovaries and adrenal glands, it is usually prone to perirenal and renal medullary adipose tissue. In this case report, we present an anastomosed hemangioma in the right kidney of a 33-year-old woman, with previous coexistence of breast cancer, in which an unusual behavior was detected, with characteristics of vascular lesion, in this case we report: The classic conditions, its heterogeneous nature and the vascular alterations that presents in different imaging modalities.

关键词： Anastomosing Hemangioma Kidney Tumor Lesion Breast Cancer

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Methodology of the data processing with ICT solutions for the evaluation of the energy and water savings

Methodology of the data processing with ICT solutions for th...

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The 2nd International Conference on Green Building Technologies and Materials(GBTM2012)

作者： Samuel domínguez Jessica Fernández-Agüera Rocío Escandn Eugenio domínguez Institute of Architecture and Building Science University of Seville2 Reina Mercedes Avenue41012 SevilleSpain

EnergyTIC(Technology,Information and Communication services for engaging social housing residents in energy and water efficiency) has put information and communication technology(ICT) solutions in place to provide end-users with methods to monitor and adapt their energy and water *** main objective of this paper is to establish a methodology to analyze,process,and organize the user information and the energy and water consumption information from the Spanish pilot *** will work with three different layers of information: (1) data provided to the user,(2) data managed for the analysis,and(3) data entered into the software "eeMeassure" to quantify the savings according to the unified criteria of the European Commission..

关键词： ICT solutions Energy Efficiency Energy and water savings Energy user’s feedback

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Tropical tree community composition and diversity variation along a volcanic elevation gradient

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Journal of Mountain Science 2022年第12期19卷 3475-3486页

作者： Ruben MARTINEZ-CAMILO Manuel MARTINEZ-MELENDEZ Nayely MARTINEZ-MIELENDEZ Derio antonio JIMENEZ-LOPEZ Mauricio JOSE-RIOS Unidad Villa Corzo Facultad de IngenieríaUniversidad de Ciencias y Artes de Chiapas30520 Villa CorzoChiapasMexico Instituto de Ciencias Biológicas Universidad de Ciencias y Artes de Chiapas29039 Tuxtla GutiérrezChiapasMexico Eizia A.C. 29045 Tuxtla GutiérrezChiapasMexico Departamento de Conservación de la Biodiversidad El Colegio de la Frontera Sur29290 San Cristóbal de las CasasChiapasMexico Orquidiario y Jardín Botánico de Comitán Secretaría de Medio Ambiente e Historia Natural30106 Comitán de DomínguezChiapasMexico Instituto de Investigación en Gestión de Riesgos y Cambio Climático Universidad de Ciencias y Artes de Chiapas29039 Tuxtla GutiérrezChiapasMexico

Unraveling the factors that determine variation of diversity in tropical mountain systems is a topic for debate in plant *** is especially true in areas where topography is complex due to volcano elevational gradients and where forests are vulnerable to human *** this study we used a set of climatic(temperature,rainfall,and radiation solar),topographic(elevation,slope aspect,and slope orientation)and human disturbance variables to determine their effect on diversity and composition patterns of a tree community,considering three slope aspects of a tropical volcano in southeastern *** sampled trees in seventy 0.1-ha plots distributed on three slope aspects of the Tacanávolcano along an elevational gradient of 1500 to 2500 *** determined diversity patterns(general tree richness,exponential of Shannon index,and pioneer species richness)with linear regression models,and for beta diversity,we used a dissimilarity index(within and between elevational bands 100 m wide).The effect of a set of environmental and human disturbance variables on tree diversity and community composition was analyzed with general linear models and multivariate analyses,*** registered 2,949 individual trees belonging to 176 species and *** average species richness and alpha diversity per plot were 13(standard deviation±6)and 9(±5),*** tree richness and alpha diversity increased in the middle part(unimodal patterns)of the elevational gradient,but pioneer species richness decreased linearly with *** variance explained by general linear models was greater in richness(32%)than in alpha diversity(25.3%).The most important predictor variables were temperature(elevational gradient),which explained the unimodal pattern(richness and alpha diversity increase at intermediate levels of temperature),and slope orientation,which explained the increase in richness and alpha diversity toward the geographic *** temperature had a signific

关键词： Composition Environmental gradient Tree diversity patterns Tropical humid cloud forest Tropical volcanoes

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Species Diversity of Entomopathogenic Fungi Infecting the Sugarcane Aphid <i>Melanaphis sacchari</i>: A Recently Introduced Pest in Mexico

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Advances in Microbiology 2019年第1期9卷 38-55页

作者： Jorge Zambrano-Gutiérrez Raquel Alatorre-Rosas María G. Carrillo-Benítez J. Refugio Lomelí-Flores Remigio A. Guzmán-Plazola Ausencio Azuara-domínguez antonio P. Terán-Vargas Programa de Fitosanidad Colegio de Postgraduados Texcoco Mexico Posgrado en Biología Instituto Tecnológico de Ciudad Victoria Ciudad Victoria Mexico Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias Campo Experimental Las Huastecas Cuauhtémoc Mexico

The sugarcane aphid, Melanaphis sacchari, is a key pest that affects sorghum in Mexico. During 2014 to 2016, in South of Tamaulipas sites and Bajio region in Guanajuato, the populations of this aphid were infected by different species of Hypocrealean fungi. Based in the morphometric identification and molecular characterization, the species associated with sugarcane aphid in South of Tamaulipas were Lecanicillium longisporum, Beauveria bassiana and Isaria javanica. In this region, the higher infection levels were caused by L. longisporum, mortality range from 30.0% to 50.0%. The presence of I. javanica and B. bassiana represented less than 26.0% and 10.0%, respectively. In Guanajuato, the species found corresponded to L. longisporum and B. bassiana. The infection levels of both species in sugarcane aphid populations in Guanajuato sites were less than 1.00%. The natural occurrence of entomopathogenic fungi on sugarcane aphid populations was associated with climactic factors such as temperature and relative humidity and development of infections was possibly affected by abiotic factors such as crop phenological stage and applications of chemical insecticides realized by farmers for control of this aphid. Further studies on the ecology and physiology of these fungi and trials to determine virulence and persistence in M. sacchari populations are needed. This is the first report on natural presence of L. longisporum, B. bassiana and I. javanica causing disease on Melanaphis sacchari in Guanajuato and Tamaulipas, Mexico.

关键词： Aphid Sorghum Hypocrealean Fungi Native Isolates Identification

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