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Perinatal Stroke and Apparent Life-Threatening Event: A Case Report

Open Journal of Emergency Medicine 2014年第3期2卷 62-66页

作者： antonella palmieri Martina Finetti Marta Bertamino Laura Banov Margherita Mancardi Giovanni Morana Salvatore Renna Emergency Department IRCCS Gaslini Genoa Italy Pediatric Reumatology Unit IRCCS Gaslini Genova Italy Hemostasis and Trombosis Unit IRCCS Gaslini Genova Italy Neurology Unit IRCCS Gaslini Genova Italy Neuroradiology Unit IRCCS Gaslini Genova Italy

To analyze how the multidisciplinary clinical, biohumoral, instrumental approach to ALTE (Apparent Life Threatening Event) episode may discover cardiovascular disease in the newborn. Introduction: In the first year of life ALTEs concern 0.8% of access to Pediatric Emergency Department. The cause of apparent life-threatening events (ALTEs) in infants reflects a differential diagnosis that includes an array of congenital or acquired disorders. Approximately 10% - 25% of ap-parent life-threatening events may remain unexplained following a thorough evaluation. Case re-port: B. E., a 2-month-old child, in wellbeing, shortly before meal, during sleep, was not responsive to repeated stimulations;he was hypotonic and unresponsive. About 15 minutes later, he pre-sented a normal tone and state of consciousness. Evaluating the referred symptoms, diagnostic protocol for ALTE was started;the Angio-MRI brain performed as second line analysis showed a focal gliotic lesion at left striatal area. The cardiological evaluation with echocardiography detected a pervium foramen ovale (PFO), with minimum shunt left-right direction. At least, biohumoral tests revealed protrombin gene heterozygosis mutation. Conclusion: Apparent Life-Threatening Events are first manifestation of stroke in infant. Discussion: This report discloses how the multidisciplinary clinical approach is essential in ALTE. The exact management of ALTE patients is very important in situations like this, when the concomitant disease is rare. In fact, arterial stroke incidence in children > 28 days of life is estimated between 1.2 and 7.9 cases/100,000 child-ren/year. However, in the last 20 years, we observed an increased incidence of stroke, probably related to two main causes: a greater attention for this disease and a major survival of children with pathology that arrange for stroke thanks to a better prevention. In conclusion, it’s a fundamental multidisciplinary approach even in following months after the events.

关键词： Perinatal Stroke Apparent Life-Threatening Events Pediatric Emergency Pro-Thrombotic Factor Congenital Heart Defect

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Co-Optimization of Behind-the-Meter and Front-of-Meter Value Streams in Community Batteries

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Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 334-345页

作者： Carmen Bas Domenech antonella Maria De Corato Pierluigi Mancarella University of Melbourne Parkville 2010VictoriaAustralia Department of Electrical and Electronic Engineering The University of ManchesterManchesterU.K. IEEE

Community batteries(CBs)are emerging to support and even enable energy communities and generally help consumers,especially space-constrained ones,to access potential techno-economic benefits from storage and support local grid ***,the economic viability of CB projects is often *** this regard,typical feasibility studies assess CB value for behind-the-meter(BTM)operation or whole-sale market participation,i.e.,front-of-meter(FOM).This work proposes a novel techno-economic operational framework that allows systematic assessment of the different options and introduces a two-meter architecture that co-optimizes both BTM and FOM benefits.A real CB project application in Australia is used to demonstrate the significant two-meter co-optimization opportunities that could enhance the business case of CB and energy communities by multi-service provision and value stacking.

关键词： Behind-the-meter community battery distributed energy resource(DER) energy community front-of-meter value stacking

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Designing for well-Being: Using facial micro-expression analysis and EEG biosensor to evaluate human responses to 2D biophilically-driven geometries

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Frontiers of Architectural Research 2024年第2期13卷 219-234页

作者： Andrea Macruz Ernesto Bueno Gustavo Sol Jaime Vega Ricardo palmieri Bing Zhao College of Architecture and Urban Planning Tongji UniversityShanghaiChina Universidade Presbiteriana Mackenzie Sao PauloBrazil Centro Universitario Belas Artes Sao PauloBrazil Universidade Anhembi Morumbi Sao PauloBrazil Universidade Federal do ABC Santo AndreBrazil

This research explores the capacity of emerging technologies to enhance well-being. It involves the generation of 2D biophilically-driven geometries to represent human-response-oriented built environments and conducts inter and intra-individual analyses to assess human responses using a range of technologies within the realms of facial micro-expression analysis and EEG biosensor use. The outcomes of this analysis allow for the grading of these geometries in terms of emotional valences, meditation levels, and subjective preferences. These graded geometries can subsequently be employed in specific architectural contexts, such as interior decor, wallpapers, furniture surfaces, or other architectural and interior components. It is an interdisciplinary effort that underscores the importance of incorporating emerging technological means with human-response-oriented design approaches to foster built environments that promote well-being.

关键词： Biophilic design Geometrical algorithmicmodeling Facial micro-expressionanalysis EEG biosensor Neuroscience

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Privacy Protection in COVID Data Tracking: Textual Analysis of the Literature

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Applied Mathematics 2024年第3期15卷 235-255页

作者： antonella Massari Viviana D’Addosio Vittoria Claudia De Nicolò Samuela L’Abbate Department of Economics Management and Business Law University of Bari Aldo Moro Bari Italy

The literary review presented in the following paper aims to analyze the tracking tools used in different countries during the period of the COVID-19 pandemic. Tracking apps that have been adopted in many countries to collect data in a homogeneous and immediate way have made up for the difficulty of collecting data and standardizing evaluation criteria. However, the regulation on the protection of personal data in the health sector and the adoption of the new General Data Protection Regulation in European countries has placed a strong limitation on their use. This has not been the case in non-European countries, where monitoring methodologies have become widespread. The textual analysis presented is based on co-occurrence and multiple correspondence analysis to show the contact tracing methods adopted in different countries in the pandemic period by relating them to the issue of privacy. It also analyzed the possibility of applying Blockchain technology in applications for tracking contagions from COVID-19 and managing health data to provide a high level of security and transparency, including through anonymization, thus increasing user trust in using the apps.

关键词： Tracking Privacy Blockchain Textual Analysis

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Antioxidant treatment for oligoasthenoteratozoospermia and varicocele:a DBPC trial to evaluate the impact of age and body mass index

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Asian Journal of Andrology 2024年第3期26卷 239-244页

作者： Gian Maria Busetto Bernarde F Rodrigues Ashraf Virmani Andrea Checchia antonella Ninivaggi Anna Ricapito Giovanni Barbieri Piero Fischetti Ugo G Falagario Pasquale Annese Nicola d’Altilia Vito Mancini Matteo Ferro Felice Crocetto Angelo Porreca Carlo Bettocchi Luigi Cormio Ashok Agarwal Giuseppe Carrieri University of Foggia Foggia 71122Italy Department of Urology and Renal Transplantation Policlinico of FoggiaFoggia 71122Italy Department of Urology Human Reproduction SectionFederal University of Sao PauloSao Paulo 05403-000Brazil Alfasigma Healthscience Utrecht 3528 BGThe Netherlands Urology Unit “G.Tatarella”HospitalCerignola 71042Italy Urology Unit European Institute of Oncology(IEO)IRCCSMilan 20142Italy University of Naples Federico II Naples80126Italy Department of Oncological Urology Veneto Institute of Oncology(IOV)IRCCSPadua 35039Italy Urology Unit “L.Bonomo”HospitalAndria 70031Italy Global Andrology Forum Moreland HillsOH 44022USA

Oxidative stress is one of the main mechanisms responsible for male *** conditions such as varicocele,obesity,advanced age,and lifestyle can lead to an increase in reactive oxygen species,causing an oxidative imbalance in the *** are sensitive to reactive oxygen species and require energy to carry out their main function of fertilizingthe *** reactive oxygen species can affect sperm metabolism,leading to immobility,impaired acrosome reaction,and celldeath,thereby impairing reproductive *** double-blind randomized study evaluated the effect of supplementation withL-carnitine,acetyl-L-carnitine,vitamins,and other nutrients on semen quality in 104 infertile patients with or without varicocele,while also investigating the impact of factors such as obesity and advanced age on *** concentration significantlyincreased in the supplemented group compared to the placebo group(P=0.0186).Total sperm count also significantly increasedin the supplemented group(P=0.0117),as did sperm motility(P=0.0120).The treatment had a positive effect on patients upto 35 years of age in terms of sperm concentration(P=0.0352),while a body mass index(BMI)above 25 kg m^(−2) had a negativeeffect on sperm concentration(P=0.0110).Results were not showing a net benefit in stratifying patients in accordance withtheir BMI since sperm quality increase was not affected by this *** conclusion,antioxidant supplementation may bebeneficial for infertile patients and has a more positive effect on younger patients with a normal weight.

关键词： aging antioxidants body mass index oligoasthenoteratozoospermia varicocele

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Statistical Analysis of Abilities to Give Consent to Health Data Processing

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Applied Mathematics 2024年第8期15卷 508-542页

作者： antonella Massari Biagio Solarino Paola Perchinunno Angela Maria D’Uggento Marcello Benevento Viviana D’Addosio Vittoria Claudia De Nicolò Samuela L’Abbate Department of Economics Management and Business Law University of Bari Aldo Moro Bari Italy Institute of Legal Medicine Department of Interdisciplinary Medicine University of Bari Aldo Moro Bari Italy Department of Economics and Finance University of Bari Aldo Moro Bari Italy

The recent pandemic crisis has highlighted the importance of the availability and management of health data to respond quickly and effectively to health emergencies, while respecting the fundamental rights of every individual. In this context, it is essential to find a balance between the protection of privacy and the safeguarding of public health, using tools that guarantee transparency and consent to the processing of data by the population. This work, starting from a pilot investigation conducted in the Polyclinic of Bari as part of the Horizon Europe Seeds project entitled “Multidisciplinary analysis of technological tracing models of contagion: the protection of rights in the management of health data”, has the objective of promoting greater patient awareness regarding the processing of their health data and the protection of privacy. The methodology used the PHICAT (Personal Health Information Competence Assessment Tool) as a tool and, through the administration of a questionnaire, the aim was to evaluate the patients’ ability to express their consent to the release and processing of health data. The results that emerged were analyzed in relation to the 4 domains in which the process is divided which allows evaluating the patients’ ability to express a conscious choice and, also, in relation to the socio-demographic and clinical characteristics of the patients themselves. This study can contribute to understanding patients’ ability to give their consent and improve information regarding the management of health data by increasing confidence in granting the use of their data for research and clinical management.

关键词： Privacy Health Data Consent Cluster Analysis Logit

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一种新型口服选择性雄激素受体调节药enobosarm在雄激素受体阳性、雌激素受体阳性和HER2阴性晚期乳腺癌中的活性和安全性(研究G200802):一项随机、开放标签、多中心、多国、平行设计的2期试验

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中国临床药理学杂志 2024年第9期40卷 1371-1371页

作者： palmieri C LINDEN H BIRRELL S N 王超群

雄激素受体在雌激素受体阳性乳腺癌中具有抑制肿瘤的作用。本研究评估了enobosarm(一种口服选择性雄激素受体调节剂)在雌激素受体(ER)阳性、人类表皮生长因子受体2(HER2)阴性和雄激素受体(AR)阳性疾病的妇女中的活性和安全性。

关键词：激素受体阳性晚期乳腺癌抑制肿瘤 G200 平行设计

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Children are not little adults:blood transfusion in children with burn injury

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Burns & Trauma 2017年第3期5卷 158-163页

作者： Tina L. palmieri Shriners Hospital for Children Northern California and the University of California Davis 2425 Stockton Blvd Suite 718 Sacramento CA 95817 USA

Blood transfusion in burns larger than 20%total body surface area (TBSA) are frequent due to operative procedures, blood sampling, and physiologic response to burn injury. Optimizing the use of blood transfusions requires an understanding of the physiology of burn injury, the risks and benefits of blood transfusion, and the indications for transfusion. Age also plays a role in determining blood transfusion requirements. Children in particular have a different physiology than adults, which needs to be considered prior to transfusing blood and blood products. This article describes the physiologic differences between children and adults in general and after burn injury and describes how these differences impact blood transfusion practices in children.

关键词： Blood transfusion Pediatric Burn injury

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Probabilistic Quantitative Temporal Constraints:Representing,Reasoning,and Query Answering

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Journal of Electronic Science and Technology 2018年第1期16卷 1-10页

作者： Paolo Terenziani antonella Andolina Dipartimento di Scienze e Innovazione Tecnologica University of Eastern PiedmontAlessandria 15121 Istituto Tecnico Commerciale Sommeiller Torino 10129

In many applications and domains,temporal constraints between actions, and their probabilities play an important role. We propose the first approach in the literature coping with probabilistic quantitative constraints. To achieve such a challenging goal, we extend the widely used simple temporal problem(STP) framework to consider ***,we propose i) a formal representation of probabilistic quantitative constraints, ii) an algorithm,based on the operations of intersection and composition,for the propagation of such temporal constraints, and iii) facilities to support query answering on a set of such constraints. As a result, we provide users with the first homogeneous method supporting the treatment(representing,reasoning,and querying) of probabilistic quantitative constraints, as required by many applications and domains.

关键词： Artificial intelligence(AI) probabilities query answering quantitative temporal constraints temporal reasoning

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100 years of high GEM concentration in the Central Italian Herbarium and Tropical Herbarium Studies Centre(Florence,Italy)

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Journal of Environmental Sciences 2020年第1期32卷 377-388页

作者： Jacopo Cabassi Valentina Rimondi Zhang Yeqing antonella Vacca Orlando Vaselli antonella Buccianti Pilario Costagliola Department of Earth Sciences University of FlorenceVia G.La Pira4-50121 FlorenceItaly CNR-Institute of Geosciences and Earth Resources Via G.La Pira4-50121 FlorenceItaly

Up to 1980 s,the most used preservative for herbaria specimens was HgCl2,sublimating at ambient air conditions;ionic Hg then reduces to Hg0(gaseous elemental mercury,GEM)and diffuses throughout poor ventilated *** GEM levels may indeed persist for decades,representing a health *** this study,we present new GEM data from the Central Italian Herbarium and Tropical Herbarium Studies Centre of the University of Florence(Italy).These herbaria host one of the largest collection of plants in the ***,HgCl2 was documented as plant preservative up to the 1920 *** surveys were conducted in July 2013 and July and December 2017,to account for temporal and seasonal *** show GEM concentrations well above those of external locations,with peak levels within specimen storage cabinets,exceeding 50,000 ng/*** concentrations up to^7800 ng/m3 were observed where the most ancient collections are stored and no ventilation systems were *** the contrary,lower GEM concentrations were observed at the first ***,lower and more homogeneously distributed GEM concentrations were measured in 2017 than in 2013 since the air-conditioning system was updated in *** concentrations were similar to other herbaria worldwide and lower than Italian permissible exposure limit of 20,000 ng/m3(8-hr working day).Our results indicate that after a century from the latest HgCl2 treatment GEM concentrations are still high,i.e.,the treatment itself is almost *** conditioning and renewing is probably the less expensive and more effective method for GEM lowering.

关键词： Gaseous elemental mercury(GEM) Mercuric chloride Herbaria Florence Health safety

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