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Laboratory markers in ulcerative colitis: Current insights and future advances

World Journal of Gastrointestinal Pathophysiology 2015年第1期6卷 13-22页

作者： Michele Cioffi antonella de rosa rosalba Serao Ilaria Picone Maria Teresa Vietri department of Biochemistry Biophysics and General PathologySecond Medical School Naples

Ulcerative colitis(UC)and Crohn’s disease(CD)are the major forms of inflammatory bowel diseases(IBD)in *** some common features,these forms can be distinguished by different genetic predisposition,risk factors and clinical,endoscopic and histological *** aetiology of both CD and UC remains unknown,but several evidences suggest that CD and perhaps UC are due to an excessive immuneresponse directed against normal constituents of the intestinal bacterial *** sometimes invasive are routine for the diagnosis and care of patients with *** of UC is based on clinical symptoms combined with radiological and endoscopic *** employment of non-invasive biomarkers is *** biomarkers have the potential to avoid invasive diagnostic tests that may result in discomfort and potential *** ability to determine the type,severity,prognosis and response to therapy of UC,using biomarkers has long been a goal of clinical *** describe the biomarkers assessed in UC,with special reference to acute-phase proteins and serologic markers and thereafter,we describe the new biological markers and the biological markers could be developed in the future:(1)serum markers of acute phase response:The laboratory tests most used to measure the acute-phase proteins in clinical practice are the serum concentration of C-reactive protein and the erythrocyte sedimentation *** biomarkers of inflammation in UC include platelet count,leukocyte count,and serum albumin and serum orosomucoid concentrations;(2)serologic markers/antibodies:In the last decades serological and immunologic biomarkers have been studied extensively in immunology and have been used in clinical practice to detect specific *** UC,the presence of these antibodies can aid as surrogate markers for the aberrant host immune response;and(3)future biomarkers:The development of biomarkers in UC will be very important in the *** progress of

关键词： Inflammatory bowel diseases Ulcerative colitis Crohn’s disease Serologic markers Acute phase response

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EFFECTS OF RIVER NETWORK WORKS AND SOIL CONSERVATION MEASURES ON RESERVOIR SILTATION

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International Journal of Sediment Research 2007年第4期22卷 273-281页

作者： Bruno MOLINO rosa VIPARELLI Annamaria de VINCENZO Prof. Department of Environmental Physics and Engineering University of Basilicata 85100 Potenza Italy

Knowledge of the morphological dynamics of a water course is essential for management of reservoir siltation. With an example of sedimentation in a reservoir in Basilicata, Italy, this paper demonstrates the effect on reservoir siltation of the hydraulic works, which are aimed to reduce sediment transport along the fluvial network and to prevent part of the sediment discharge from reaching the lake. The effect depends on the river type and on the the geological features of river basin slopes. The paper also shows how mass erosion can significantly contribute to development of reservoir siltation. Finally, preliminary results are provided about the time needed for river training works to be effective.

关键词： Water resources management River hydraulic works Soil erosion Landslide Reservoir siltation

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Assessment of lead pollution in topsoils of a southern Italy area: Analysis of urban and peri-urban environment

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Journal of Environmental Sciences 2015年第7期27卷 179-187页

作者： Ilaria Guagliardi Domenico Cicchella rosanna de rosa Gabriele Buttafuoco department of Biology Ecology and Earth Sciences University of Calabria department of Science and Technology University of Sannio National Research Council of Italy Institute for Agricultural and Forest Systems in the Mediterranean (ISAFOM)

Exposure to lead（Pb） may affect adversely human health. Mapping soil Pb contents is essential to obtain a quantitative estimate of potential risk of Pb contamination. The main aim of this paper was to determine the soil Pb concentrations in the urban and peri-urban area of Cosenza-Rende to map their spatial distribution and assess the probability that soil Pb concentration exceeds a critical threshold that might cause concern for human *** were collected at 149 locations from residual and non-residual topsoil in gardens,parks, flower-beds, and agricultural fields. Fine earth fraction of soil samples was analyzed by X-ray Fluorescence spectrometry. Stochastic images generated by the sequential Gaussian simulation were jointly combined to calculate the probability of exceeding the critical threshold that could be used to delineate the potentially risky areas. Results showed areas in which Pb concentration values were higher to the Italian regulatory values. These polluted areas were quite large and likely, they could create a significant health risk for human beings and vegetation in the near future. The results demonstrated that the proposed approach can be used to study soil contamination to produce geochemical maps,and identify hot-spot areas for soil Pb concentration.

关键词： Urban and peri-urban soils Geochemistry Lead Soil pollution Stochastic simulation

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Antiplatelet therapy in very elderly and comorbid patients with acute coronary syndromes

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Journal of Geriatric Cardiology 2019年第2期16卷 103-113页

作者： Roberta de rosa Federico Piscione Gennaro Galasso Stefano de Servi Stefano Savonitto department of Medicine Surgery and DentistrySchola Medica SalemitanaUniversity of SalernoItaly IRCCS Multimedica Sesto San Giovanni(MI)Italy Cardiovascular department Alessandro Manzoni HospitalLeccoItaly

With population ageing and rise of life expectancy,a progressively increasing proportion of patients presenting with an acute coronary syndrome(ACS)are older adults,including those at extreme chronological *** amounts of data,including randomized clinical trials,have shown that the benefits of an early revascularization are maintained also at very old age,resulting in improved outcome after an acute coronary *** the contrary,the optimal antiplatelet therapy(APT)remains unclear in these patients,because of both safety and efficacy ***,age-related multiple organ dysfunction and high prevalence of comorbidities may on the one hand reduce the therapeutic effects of administered drugs;on the other hand,it leads to increased vulnerability to drug toxicity and side ***,management of APT is particularly challenging in elderly patients because of higher risk of both ischemic and bleeding *** aim of the present paper is to review the current evidence,gaps in knowledge and ongoing research regarding APT in the setting of an ACS in elderly and very elderly patients,and in those with significant comorbidities including chronic kidney disease,diabetes mellitus and frailty.

关键词： Acute coronary syndrome Antiplatelet therapy The elderly

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Rheological and stability analysis of cement pastes incorporating silica-based wastes

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Particuology 2024年第6期89卷 144-152页

作者： Julia da rosa Martins Janaíde Cavalcante Rocha Dachamir Hotza Luciano Senff Graduate Program in Materials Science and Engineering(PPGMAT) Federal University of Santa Catarina(UFSC)Florianópolis88040-900SCBrazil Graduate Program in Civil Engineering(PPGEC) Federal University of Santa Catarina(UFSC)Florianópolis88040-900SCBrazil Graduate Program in Chemical Engineering(POSENQ) Federal University of Santa Catarina(UFSC)Florianópolis88040-900SCBrazil department of Mobility Engineering Federal University of Santa Catarina(UFSC)Joinville89219-600SCBrazil

This study investigates the influence of waste characteristics,especially zeta potential,on the properties of cement pastes and *** focus is to evaluate the impact of the zeta potential of cement particles and waste materials on the sedimentation speed,rheology,and hardening time of stabilized cement *** Cement II F 40,retarder additive,silica,and fly ash were used in the *** pastes were prepared,and during the stabilization period,their rheological properties and pH were *** zeta potential and sedimentation speed of the cement and waste particles were measured at the pH that the pastes presented during the entire stabilization *** the stabilization period,the pastes were subjected to the hardening time *** zeta potential analyses revealed diverse values for the different powder types,with the cement particles exhibiting a zeta potential of−3.0 mV,the silica particles exhibiting−10.5 mV,and the fly ash particles exhibiting−20.3 *** influence of the high zeta potential modulus was observed on the sedimentation speed,with the solution containing fly ash exhibiting a speed of 40.01μm/s,whereas the solution containing only cement exhibited a speed of 99.38μm/*** the pastes,the results indicate that the presence of fly ash particles with a significantly negative zeta potential led to a 16%reduction in hardening time compared to particles with a lower modulus of zeta *** tests showed that the inclusion of fly ash particles prevented the formation of *** the zeta potential influenced agglomerate formation and hardening time,it was found to have no effect on yield stress or viscosity.

关键词： Wastes Zeta potential Setting time Rheometry

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Bipartite liver: an incidental rare anomaly of the liver

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Hepatobiliary Surgery and Nutrition 2022年第4期11卷 649-650页

作者： Michele de rosa Graziano Ceccarelli department of General Surgery “San Giovanni Battista”HospitalFolignoPerugiaItaly

Bipartite liver is a rare congenital anomaly without phylogenetic significance,which needs to be known for the potential risk of torsion or internal gastrointestinal herniation and also in the pre-operative planning o... 详细信息

关键词： liver operative rare

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Environmental degradation through mining for energy resources:The case of the shrinking Laguna Santa rosa wetland in the Atacama Region of Chile

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Energy Geoscience 2022年第2期3卷 182-190页

作者： Mohammad Ayaz Alam rosa Sepúlveda departamento de Geología Facultad de IngenieríaUniversidad de AtacamaAvenida Copayapu 485CopiapoRegion de AtacamaChile

As the world strives to replace fossil fuels with clean energy e reflected by global surge in the number of electric vehicles e the environmental impact of mining all the lithium(Li)needed to enable such a transformation has become a problem in its own *** South America,the biggest problem is the excessive use of water in Li extraction process in one of the driest areas in the *** from causing severe friction over water rights between local communities and mining companies,it puts enormous pressure on the region's fragile and poorly understood wetland *** are one of the most threatened ecosystems on the Earth,despite their great importance as habitats for a vast number of species and corresponding to one of the most productive *** work is the outcome of an investigation on Laguna Santa rosa's(LSR)vulnerability resulting from ongoing metal mining operations in its surroundings that require a large volume of water extracted from local aquifers,in addition to a high evaporation rate in the *** groundwater-dependent wetland will soon be further vulnerable with the commencement of water-intensive Li mining at Salar de Maricunga,with the extraction project already having an environmental impact study *** of this wetland protected under the Ramsar Convention and home to numerous wildlife species habiting this highland sector of the Andean Cordillera is vital for the associated *** variation in the water surface area of LSR has been deciphered through the application of a Landsat-5 Thematic Mapper(TM)satellite image *** has been done both for the hydrological year 2016e2017 and 1993-2014 period.A decreasing trend in the water surface area of LSR,a hypersaline lake at the southern extreme of Salar de Maricunga,a salt flat in the Atacama Region of Chile,was observed through the study of satellite images between 1993 and 2014,showing shrinking of this ***,this shrinking t

关键词： Laguna Santa rosa Salar de Maricunga Lithium Water Wetland Ecosystem

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Ocular ultrasound evaluation of optic nerve sheath diameter in military environments

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Military Medical Research 2019年第3期6卷 272-274页

作者： Maddalena de Bernardo Livio Vitiello Palmiro Cornetta Nicola rosa department of Medicine Surgery and Dentistry "Scuola Medica Salernitana" University of Salerno

In this letter to the Editor, we would like to comment on the article by Betcher et al., concerning the possibility of teaching military trainees to obtain accurate optic nerve sheath diameter measurements, using a brief didactic and a hands-on training session. In particular, this letter notes the importance of the measurement of optic nerve sheath diameter in detecting the eventual elevated intracranial pressure following traumatic brain injury, highlights several limitations in the use of B-scan for such a purpose and suggests a more accurate evaluation with the standardized A-scan.

关键词： Blooming effect Intracranial pressure Optic nerve sheath diameter

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Thermally stable ultrafine grained copper induced by CrB/CrB_(2) microparticles with surface nanofeatures via regular casting

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Journal of Materials Science & Technology 2020年第23期58卷 55-62页

作者： Gongcheng Yao Chezheng Cao Shuaihang Pan Jie Yuan Igor de rosa Xiaochun Li department of Materials Science and Engineering University of CaliforniaLos AngelesCA 90095USA department of Mechanical and Aerospace Engineering University of CaliforniaLos AngelesCA 90095USA

Ultrafine-grained(UFG)/nanocrystalline materials possess novel properties. Refining as-solidified grains of metals to the ultrafine and even nanometer scale by nanoparticles via slow cooling has been recently discovered. Here, we report that microparticles(CrB and CrB_(2)) with surface nanofeatures can also enable ultrafine/nano grains via slow cooling. CrB/CrB_(2) microparticles, formed by coalescence of nanoparticles in Cu matrix, display surface nanofeatures, which induce substantial grain refinement and stabilization down to the ultrafine/nano scale. The UFG Cu/Cr B and Cu/CrB_(2) samples exhibit exceptional thermal stability, comparable to UFG Cu induced by nanoparticles, without coarsening after annealing at 600°C for 1 h. The microhardness, strengths, and Young's moduli of the Cu/Cr B and Cu/CrB_(2) samples are significantly enhanced over pure Cu. This discovery has great potential to advance the mass production UFG/nanocrystalline for widespread applications.

关键词： Copper Microparticles with nanofeatures Casting Ultrafine grains Thermal stability

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A methodological approach for estimating turbidity in a river

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International Journal of Sediment Research 2011年第1期26卷 112-119页

作者： Annamaria de VINCENZO Bruno MOLINO rosa VIPARELLI Pompilio CARAMUSCIO department of Environmental Physics and Engineering University of Basilicata85100 PotenzaItaly SAVA department University of Molise86100 CompobassoItaly 3. ENEL R&D Department72020 Tutorano(Br)Italy

During the operations of purging and disposal of sediments of a reservoir it is necessary to know the values of turbidity in the river downstream in natural condition,in the absence of dams or river training *** paper shows that under these conditions the ratio of the average values of sediment discharge to the annual maximum value of water discharge is a function of the average annual *** can be considered as representative synthetic index of the climatic conditions,the lithological features and the land cover of the basin,and the geometric characteristics of the river *** proposed relationship of sediment discharge as a function of water discharge were validated on the basis of data collected from different Italian regions that have very different morphological,geo-lithological and rainfall features and that are characterised by a basin area changing between a few dozen and thousands of square *** results can be considered satisfying.

关键词： Soil erosion Reservoir siltation Flushing Turbidity Sediment transportation

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