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Blockchain Energy: Blockchain in Future Energy Systems

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Journal of Electronic Science and Technology 2019年第4期17卷 317-331页

作者： Bernd Teufel anton Sentic Mathias Barmet international institute of management in technology University of Fribourg

The ongoing,in-depth transformation of the electricity sector towards increased use of alternative,renewable energy sources extends beyond a simple decentralisation drive in the electricity *** transformation process is characterised by the interplay of old and new technologies from the energy sector as well as structural coupling with other sectors,such as the information and communications technology(ICT),enabling the technology transfer as well as market entry by information technology(IT)***-based technologies have the potential to play a key role in this transition by offering decentralised interfaces and systems as well as an alternative approach to the current organisation form of the energy *** paper discusses the applicability and prospects for blockchain-based technologies in the energy sector,which are described using the term“blockchain energy”.For the purposes of this study,blockchain energy encompasses all socio-technical and organisational configurations in the energy sector based on the utilisation of the blockchain principle for energy trading,information storage,and/or increased transparency of energy flows and energy *** the following chapters,the authors present and discuss the current transformation in the electricity market,followed by a review of the different utilisation possibilities for blockchain technologies in the energy sector and a discussion of the barriers and potential for blockchain energy using a transition studies ***,the opportunities and risks of blockchain energy are discussed.

关键词： Blockchain energy management crowd energy transition research.

Polypeptide Brushes Grown via Surface-initiated Ring-opening Polymerization of α-Amino Acid N-Carboxyanhydrides

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Chinese Journal of Polymer Science 2015年第7期33卷 931-931,932-946页

作者： Yong Shen 李志波 Harm-anton Klok Laboratory of Polymer Physics and Chemistry Institute of Chemistry Chinese Academy of Sciences School of Polymer Science and Engineering Qingdao University of Science and Technology cole Polytechnique Fédérale de Lausanne (EPFL) Institut des Matériaux and Institut des Sciences et Ingénierie Chimiques Laboratoire des Polymères Batiment MXD Station 12 CH-1015 Lausanne Switzerland

Polypeptide brushes are attractive platforms to generate functional and responsive interfaces that are of potential interest due to their possible biodegradability, biocompatibility and tunable secondary structures. Surface-initiated ringopening polymerization（SI-ROP） of α-amino acid N-carboxyanhydrides represents a powerful and versatile strategy to generate polypeptide brushes. This review is an attempt to capture the state-of-the-art in this field and highlights the latest developments in several selected areas. In addition to presenting an overview of the synthetic methods that have been used to generate polypeptide brushes via SI-ROP, this article will discuss the preparation of patterned polypeptide brushes, the conformational properties of surface-tethered polypeptides, ways to control chain orientation at surfaces as well as properties and applications of these thin polymer films.

关键词： Polypeptide brushes Surface α-Amino acid N-carboxyanhydrides Ring-opening polymerization Secondary structure

Polyethylene glycol fusion repair of severed rat sciatic nerves reestablishes axonal continuity and reorganizes sensory terminal fields in the spinal cord

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Neural Regeneration Research 2025年第7期20卷 2095-2107页

作者： Emily A.Hibbard Liwen Zhou Cathy Z.Yang Karthik Venkudusamy Yessenia Montoya Alexa Olivarez George d.Bittner dale R.Sengelaub Program in Neuroscience Indiana UniversityBloomingtonINUSA department of Neuroscience University of Texas at AustinAustinTXUSA

Peripheral nerve injuries result in the rapid degeneration of distal nerve segments and immediate loss of motor and sensory functions;behavioral recovery is typically *** used a plasmalemmal fusogen,polyethylene glycol(PEG),to immediately fuse closely apposed open ends of severed proximal and distal axons in rat sciatic *** have previously reported that sciatic nerve axons repaired by PEG-fusion do not undergo Wallerian degeneration,and PEG-fused animals exhibit rapid(within 2–6 weeks)and extensive locomotor ***,our previous report showed that PEG-fusion of severed sciatic motor axons was non-specific,i.e.,spinal motoneurons in PEG-fused animals were found to project to appropriate as well as inappropriate target *** this study,we examined the consequences of PEG-fusion for sensory axons of the sciatic *** adult male and female rats(Sprague–dawley)received either a unilateral single cut or ablation injury to the sciatic nerve and subsequent repair with or without(Negative Control)the application of *** action potentials recorded immediately after PEG-fusion repair confirmed conduction across the injury *** success of PEG-fusion was confirmed through Sciatic Functional Index testing with PEG-fused animals showing improvement in locomotor function beginning at 35 days *** 2–42 days postoperatively,we anterogradely labeled sensory afferents from the dorsal aspect of the hindpaw following bilateral intradermal injection of wheat germ agglutinin conjugated horseradish ***-fusion repair reestablished axonal *** to unoperated animals,labeled sensory afferents ipsilateral to the injury in PEG-fused animals were found in the appropriate area of the dorsal horn,as well as inappropriate mediolateral and rostrocaudal ***,despite having intact peripheral nerves,similar reorganizations of labeled sensory afferents were also observed contralateral to the injury and repa

关键词： axotomy dorsal horn peripheral nerve injury plasticity polyethylene glycol(PEG) sciatic nerve sensory terminals wheat germ agglutinin horseradish peroxidase

differential effects of adulterated versus unadulterated forms of linoleic acid on cardiovascular health

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Journal of Integrative Medicine 2013年第1期11卷 2-10页

作者： Stephen d. anton Kacey Heekin Carrah Simkins Andres Acosta department of Aging and Geriatric Research University of FloridaGainesville Florida 32611 USA department of Medicine University of FloridaGainesville Florida 32611 USA

According to the classic ＂diet-heart＂ hypothesis, high dietary intake of saturated fats and cholesterol combined with low intake of polyunsaturated fats can increase levels of serum cholesterol and lead to the development of atherogenic plaques and ultimately cardio- vascular diseases. Recently, the beneficial health effects of omega-6 polyunsaturated fatty acids, particularly linoleic acid （LA）, on cardiovascular health have been called into question with some scientists suggesting that consumption of LA should be reduced in Western countries. The focus of this critical review is on the controversy surrounding the effects of dietary intake of LA on cardiovascular health. Specifically, we critically examined the effects of both unadulterated and adulterated forms of LA on cardiovascular health outcomes based on findings from epidemiological studies and randomized controlled trials. Additionally, we address common concems surrounding dietary intake of LA regarding its relationship with arachidonic acid, the ratio of omega-6 to omega-3 fatty acids, and its relationship with inflammation. Our critical review indicates that unadulterated forms of LA are cardioprotective and should be consumed as part of a healthy diet. In contrast, abundant evidence now indicates that adulterated forms of LA, predominantly hydrogenated vegetable oils, are atherogenic and should not be considered part of a healthy diet. The ability to adulterate the natural omega-6 fatty acid, LA, has contributed to mixed findings regarding the effects of this fatty acid on cardiovascular health. Thus, it is critical that the source of LA be taken into account when drawing conclusions about the physiological effects of this fatty acid. The findings of the present review are in line with current dietary recommendations of the American Heart Association.

关键词： diet fatty acids linoleic acids cardiovascular diseases review

Surgery for obstructed defecation syndrome-is there an ideal technique

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World Journal of Gastroenterology 2015年第1期21卷 1-5页

作者： Stefan Riss anton Stift department of General Surgery Medical University of ViennaA-1090 ViennaAustria

Obstructive defecation syndrome(OdS) is a common disorder with a considerable impact on the quality of life of affected *** for OdS remains a challenging *** exists a great variety of operative techniques to treat patients with *** to the surgeon's preference the approach can be transanal,transvaginal,transperineal or *** techniques have its advantages and ***,high evidence based studies are significantly lacking in literature,thus making accurate assessments *** patient's selection is crucial to achieveoptimal functional *** is mandatory to assess not only defecation disorders but also evaluate overall pelvic floor symptoms,such as fecal incontinence and urinary disorders for choosing an appropriate and tailored *** investigation is essential but may not explain complaints of every patient.

关键词： Obstructive defecation syndrome defecatory disorde

Acetabular cup version modelling and its clinical applying on plain radiograms

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World Journal of Orthopedics 2017年第12期8卷 929-934页

作者： anton denisov Stanislav Bilyk anton Kovalenko Orthopedic department Vreden Russian Research Institute of Traumatology and Orthopedics

AIM To measure the sensitivity and specificity of the cup version assessment by using only anteroposterior hip and pelvis views, evaluate the incidence of inadequate cup version in patients with repeated dislocations after total hip arthroplasty(THA). METHOdS Radiographic retrospective analysis of 2 groups of patients, with follow up of 6-60 mo, after undergoing primary THA. First group of 32 patients(20 female, 12 male) with unilateral THA(32 hips) required early revision arthroplasty for reasons of dislocation. The mean age and mode were 59(from 38 to 83) and 66 ages respectively. The average body mass index(BMI) was 24.2(from 17.7 to 36.3), mode 23.9. Second group was consisted of 164 patients(101 female, 63 male) without dislocations during the follow-up period(170 hips). Among them 6 patients required bilateral THA. The mean age was 60(from 38 to 84) and mode 59. BMI was 24.8(17.2-36.8), mode 25.2. Clinical significance of the cup anteversion sign was estimated with cross tabulation 2 × 2. RESULTS The value of the χ~2 yates was 10.668(P d specificity was 92%(95%CI: 88%-96%). Relative risk of dislocation in patients with SAI was 3.4(95%CI: 1.8-6.3). CONCLUSION This method provides the surgeons with the ability to perform a reliable and simple qualitative assessment of the acetabular component version. It can be useful during patient examination with early loosening of the implant, dislocations, and impingement. Additionally, it can provide necessary information during planning of revision surgery, especially when considering question about cup replacement, although final assessment of the cup position should be done with a computed tomography scan.

关键词： Hip arthroplasty Acetabular component Retroversion dislocation

Controlling flowering of Medicago sativa(alfalfa)by inducing dominant mutations

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Journal of Integrative Plant Biology 2022年第2期64卷 205-214页

作者： Maurizio Junior Chiurazzi anton Frisgaard Nørrevang Pedro García Pablo d.Cerdán Michael Palmgren Stephan Wenkel NovoCrops Center University of CopenhagenThorvaldsensvej 40Frederiksberg C1871 Denmark Copenhagen Plant Science Centre University of CopenhagenThorvaldsensvej 40Frederiksberg C1871 Denmark department of Plant and Environmental Sciences University of CopenhagenThorvaldsensvej 40Frederiksberg C1871 Denmark Fundación Instituto Leloir IIBBA-CONICETAvenida Patricias Argentinas 435Buenos Aires1405 Argentina

Breeding plants with polyploid genomes is challenging because functional redundancy hampers the identification of loss-of-function *** sativa is tetraploid and obligate outcrossing,which together with inbreeding depression complicates traditional breeding approaches in obtaining plants with a stable growth *** dominant mutations would provide an alternative strategy to introduce domestication traits in plants with high gene *** we describe two complementary strategies to induce dominant mutations in the *** genome and how they can be relevant in the control of flowering ***,we outline a genome-engineering strategy that harnesses the use of microProteins as developmental *** are small proteins that appeared during genome evolution from genes encoding larger *** allows us to retrace evolution and create microProtein-coding genes de ***,we provide an inventory of genes regulated by microRNAs that control plant *** respective gene transcripts microRNA-resistant by inducing point mutations can uncouple microRNA ***,we investigated the recently published genomes of *** and provide an inventory of breeding targets,some of which,when mutated,are likely to result in dominant traits.

关键词： flowering time genome-engineering Medicago sativa microProtein microRNA

Weak-strong uniqueness for the compressible Navier-Stokes equations with a hard-sphere pressure law

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Science China Mathematics 2018年第11期61卷 2003-2016页

作者： Eduard Feireisl Yong Lu antonín Novotny Institute of Mathematics Academy of Sciences of the Czech Republic department of Mathematics Nanjing University IMATH University of Toulon

We consider the Navier-Stokes equations with a pressure function satisfying a hard-sphere *** means the pressure,as a function of the density,becomes infinite when the density approaches a finite critical *** some structural constraints imposed on the pressure law,we show a weak-strong uniqueness principle in periodic spatial *** method is based on a modified relative entropy inequality for the *** main difficulty is that the pressure potential associated with the internal energy of the system is largely dominated by the pressure itself in the area close to the critical *** a result,several terms appearing in the relative energy inequality cannot be controlled by the total energy.

关键词： Navier-Stokes equations hard-sphere pressure weak-strong uniqueness

Machine-learning the configurational energy of multicomponent crystalline solids

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npj Computational Materials 2018年第1期4卷 191-197页

作者： Anirudh Raju Natarajan anton Van der Ven Materials department University of CaliforniaSanta Barbara 93106 CAUSA

Machine learning tools such as neural networks and Gaussian process regression are increasingly being implemented in the development of atomistic ***,we develop a formalism to leverage such non-linear interpolation tools in describing properties dependent on occupation degrees of freedom in multicomponent ***-adapted cluster functions are used to differentiate distinct local *** local features are used as input to neural networks that reproduce local properties such as the site *** apply the technique to reproduce a synthetic cluster expansion Hamiltonian with multi-body interactions,as well as the formation energies calculated from first-principles for the intercalation of lithium into *** formalism and results presented here show that complex multi-body interactions may be approximated by non-linear models involving smaller clusters.

关键词： solids cluster multicomponent