检索结果-南通市图书馆

Volumetric helical additive manufacturing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Advanced Manufacturing) 2023年第2期4卷 48-56页

作者： antoine Boniface Florian Mattre Jorge Madrid-Wolff Christophe Moser Laboratory of Applied Photonics Devices School of EngineeringEcole Polytechnique Fédérale de LausanneCH-1015 LausanneSwitzerland

3D printing has revolutionized the manufacturing of volumetric components and structures for various *** to the advent of photocurable resins,several fully volumetric light-based techniques have been recently developed to push further the current limitations of 3D *** fast,this new generation of printers cannot fabricate objects whose typical size exceeds the centimeter without severely affecting the final *** on tomographic volumetric additive manufacturing,we propose a method for volumetric helical additive manufacturing(VHAM)multi-cm scale structures without magnifying the projected *** consists of illuminating the photoresist while the latter follows a helical *** movement allows to increase the printable object’s ***,we off-center the modulator used for projecting the light patterns to double the object’s lateral *** demonstrate experimentally the interest of using these two tricks for printing larger objects(up to 3 cm×3 cm×5 cm)with fine details(650μm)and short print time(<10 min).

关键词： Volumetric additive manufacturing Photolithography Light-based 3D printing Tomography

Specific alterations of regional myocardial work in strength-trained athletes using anabolic androgenic steroids compared to athletes with genetic hypertrophic cardiomyopathy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2023年第4期12卷 477-485页

作者： antoine Grandperrin Frédéric Schnell Erwan Donal Elena Galli Christophe Hedon Olivier Cazorla Stéphane Nottin Avignon University LaPEC UPR 4278Avignon F-84000France Rennes University CHU RennesInsermLTSI-UMR 1099Rennes F-35000France Montpellier University PhyMedExpINSERMCNRSPhysiology and Experimental Heart and Muscle MedicineMontpellier 34295France

Background:Strength-trained athletes using anabolic androgenic steroids(AAS)have left ventricular(LV)hypertrophy and myocardial fibrosis that can lead to sudden cardiac death.A similar feature was described in athletes with hypertrophic cardiomyopathy(HCM),which complicates the diagnosis for *** this context,we aimed to compare the LV function of the 2 populations by measuring global and regional strain and myocardial work using speckle-tracking ***:Twenty-four strength-trained asymptomatic athletes using AAS(AAS-Athletes),22 athletes diagnosed with HCM(HCM-Athletes),and 20 healthy control athletes(Ctrl-Athletes)underwent a resting echocardiography to assess LV *** evaluated LV global and regional strains and myocardial work,with an evaluation of the constructive work(CW),wasted work,and work efficiency(WE).Results:Compared to Ctrl-Athletes,both AAS-Athletes and HCM-Athletes had a thicker interventricular septum,with maj ored values in *** strain was reduced in AAS-Athletes and even more in ***,global WE was significantly diminished in both AAS and HCM-Athletes(93%±2%in Ctrl-Athletes,90%±4%in AAS-Athletes,and 90%±5%in HCM-Athletes(mean±SD);p<0.05).Constructive work and WE regional analysis showed specific alterations,with the basal septal segments preferentially affected in AAS-Athletes,and both septal and apical segments affected in ***:The regional evaluation of myocardial work reported specific alterations of the major LV hypertrophy induced by the regular use of AAS compared to the LV hypertrophy due to *** finding could help clinicians to differentiate between these 2 forms of pathological hypertrophy.

关键词： Anabolic androgenic steroids Hypertrophic cardiomyopathy Left ventricular function Myocardial work Speckle-tracking echocardiography

Trends in incidence and management of cancer of the ampulla of Vater

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第29期20卷 10144-10150页

作者： Florian Rostain Samia Hamza antoine Drouillard Jean Faivre Anne-Marie Bouvier C?me Lepage Registre Bourguignon des Cancers Digestifs INSERM U866CHU de DijonFaculté de Médecine21079 Dijon CedexFrance

AIM: To provide trends in incidence, management and survival of cancer of the ampulla of Vater in a well-defined French population.

关键词： Cancer of the ampulla of Vater Incidence Survival Treatment Epidemiology

Genetics of seed flavonoid content and antioxidant activity in cowpea(Vigna unguiculata L. Walp.)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Crop Journal 2016年第5期4卷 391-397页

作者： Maina antoine Nassourou Yanou Nicolas Njintang Tchiagam Jean-Baptiste Noubissié Richard Marcel Nguimbou Joseph Martin Bell Department of Biological Sciences Faculty of Science University of Ngaoundéré Department of Food Science and Nutrition ENSAI University of Ngaoundéré Genetics and Plant Breeding Unit Department of Plant Biology Faculty of Science University of Yaoundé I

Information about the type of gene action governing the inheritance of cowpea seed flavonoid content and antioxidant activity is prerequisite for starting an effective breeding program for developing improved varieties. For this purpose, half-diallel crosses among seven diverse parents were made. The homozygous parents and 21 F1 hybrids were evaluated at Maroua in the Sudano-Sahelian zone of Cameroon using a randomized complete block design with three replicates. Flour samples produced from decorticated seeds were used for biochemical analysis. Analysis of variance showed significant differences(P < 0.001) among genotypes for the studied traits with ranges of 363.6–453.9 mg rutin equivalent per 100 g dry weight(DW) for total flavonoids, 13.38–30.73 mg ascorbic acid equivalent per 1 g DW for ferric iron reducing activity, 70.98–266.93 mg trolox equivalent per 100 g DW for 2,2-diphenyl-1-picrylhydrazyl(DPPH) free radical scavenging activity, and 90.93–370.62 mg trolox equivalent per 100 g DW for 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)(ABTS) free radical scavenging activity. Both additive and non-additive gene effects were significant in the genetic control of these traits, but dominance variance was greater than additive variance. The traits were mainly controlled by overdominance model suggesting a selection in the delayed ***- and narrow-sense heritability estimates varied from 0.90 to 0.99 and from 0.12 to 0.45,respectively. The variances due to both general and specific combining ability were highly significant for all studied traits. Recessive alleles had positive effects on DPPH and ABTS scavenging activities, whereas dominant alleles had positive effects on flavonoid content and ferric iron reducing activity. These results could help cowpea breeders to improve the antioxidant potential of cowpea seeds by appropriate selection.

关键词： Cowpea Genetic improvement Diallel analysis Antioxidant properties

The boys are back in town: Rethinking the function of ribosomal DNA repeats in the genomic era

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2023年第3期16卷 514-516页

作者： Francesca B.Lopez Peter C.McKeown antoine Fort Galina Brychkova Charles Spillane Genetics and Biotechnology Laboratory Plant&AgriBiosciences Research Centre(PABC)Ryan InstituteUniversity of GalwayH91 REW4 GalwayIreland Present address:Department of Plant Biology and Genome Center University of CaliforniaDavisUC Davis Genome CenterDavisCA 95616USA

Next-generation sequencing technological advances,affording high-throughput,scalable,and fast assemblies,have enabled genome editing techniques that allow us to remove,insert,and modify genes for rapid and precise fun... 详细信息

关键词： remove precise function

Dyslipidemia in Adults with Type 2 Diabetes in a Rural Community in Ganadougou, Mali: A Cross-Sectional Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Diabetes Mellitus 2024年第2期14卷 133-152页

作者： Abdoulaye Diawara Djibril Mamadou Coulibaly Drissa Kone Mama A. Traore Drissa Konaté Dicko S. Bazi Oumar Kassogue Djeneba Sylla Fatoumata Gniné Fofana Oudou Diabaté Mariam Traore Ibrahim antoine Nieantao Kaly Keїta Mamadou Diarra Olivia Smith Jian Li Cheickna Cisse Talib Yusuf Abbas Crystal Zheng Segun Fatumo Kassim Traore Mamadou Wele Mahamadou Diakité Seydou O. Doumbia Jeffrey G. Shaffer University of Sciences Techniques and Technologies of Bamako Bamako Mali National Federation of Community Health Associations Bamako Mali Department of Tropical Medicine Medical Microbiology & Pharmacology John A. Burns School of Medicine University of Hawaii Manoa Honolulu USA Department Biostatistics and Data Science School of Public Health and Tropical Medicine Tulane University New Orleans USA Department of Biotechnology and Computer Science Burhani College Mazgaon Mumbai India School of Medicine Tulane University New Orleans USA Medical Research Council Uganda Virus Research Institute Entebbe Uganda London School of Hygiene and Tropical Medicine London UK Departement of Biochemistry and Genetics Duquesne University College of Medicine Pittsburgh USA

Dyslipidemia is a disorder where abnormally lipid concentrations circulate in the bloodstream. The disorder is common in type 2 diabetics (T2D) and is linked with T2D comorbidities, particularly cardiovascular disease. Dyslipidemia in T2D is typically characterized by elevated plasma triglyceride and low high-density lipoprotein cholesterol (HDL-C) levels. There is a significant gap in the literature regarding dyslipidemia in rural parts of Africa, where lipid profiles may not be captured through routine surveillance. This study aimed to characterize the prevalence and demo-graphic profile of dyslipidemia in T2D in the rural community of Ganadougou, Mali. We performed a cross-sectional study of 104 subjects with T2D in Ganadougou between November 2021 and March 2022. Demographic and lipid profiles were collected through cross-sectional surveys and serological analyses. The overall prevalence of dyslipidemia in T2D patients was 87.5% (91/104), which did not differ by sex (P = .368). High low-density lipoprotein cholesterol (LDL-C) was the most common lipid abnormality (78.9%, [82/104]). Dyslipidemia was associated with age and hypertension status (P = .013 and.036, respectively). High total and high LDL-C parameters were significantly associated with hypertension (P = .029 and .006, respectively). In low-resource settings such as rural Mali, there is a critical need to improve infrastructure for routine dyslipidemia screening to guide its prevention and intervention approaches. The high rates of dyslipidemia observed in Gandadougou, consistent with concomitant increases in cardiovascular diseases in Africa suggest that lipid profile assessments should be incorporated into routine medical care for T2D patients in African rural settings.

关键词： Cholesterol Cross-Sectional Study Dyslipidemia Lipids Mali Type 2 Diabetes

A novel route for the synthesis of androgen receptor antagonist enzalutamide

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2023年第6期34卷 449-453页

作者： Xiangguo Meng Siju Bi Shixin Jin Kai Wu Shanchao Wu Lei Shao Pierre-antoine Bonnet Chunquan Sheng College of Pharmacy Shanghai University of Medicine and Health SciencesShanghai 201318China Department of Medicinal Chemistry School of PharmacySecond Military Medical UniversityShanghai 200433China State Key Lab of Anti-Infectives Shanghai Institute of Pharmaceutical IndustryChina State Institute of Pharmaceutical IndustryShanghai 201203China IBMM Faculty of PharmacyMontpellier UniversityCNRSENSCM34093 Montpellier Cedex 5France

A novel route of enzalutamide was developed in five *** from 4-amino-2-(trifluoromethyl)benzonitrile(7)and Boc-2-aminoisobutyric acid(16),condensation,deprotection,Ullmann coupling,cyclization and amination provided enzalutamide in 41.0%total *** route avoids the using of toxic chemical,unstable intermediate and high-risk *** is a potential efficient and economical procedure for industrialization.

关键词： Enzalutamide Condensation Deprotection Ullmann coupling Cyclization Amination

Disruption of biofilms from sewage pipes under physical and chemical conditioning

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2009年第1期21卷 120-126页

作者： Charbel Mahfoud antoine El Samrani Rita Mouawad Walid Hleihel Rim El Khatib Bruno S. Lartiges Nam Ouani Holy Spirit University of Kaslik(USEK) Faculty of Sciences and Computer Engineering Department of Chemistry and Life SciencesWater and Environment Laboratory. P.B. 446JouniehLebanon Nancy University LEM-ENSG/INPL-CNRSPole de l'Eau15Avenue du CharmoisBP 40-F-54501 Vandoeuvre CedexFrance

Biofilms grown inside two sewage collecting pipes located in industrial and residential areas are studied. Bacterial biomass inside three layers of biofilms was evaluated. Biofilm cohesion under different mixing rate and ionic strength was also investigated. Effects of physical and chemical parameters in the biofilms were evaluated by monitoring turbidity, chemical and biochemical oxygen demands. Extracted organic matter from biofilms was partitioned to polar, aromatic and saturated fractions using activated silica column chromatography. Results revealed that bacterial biomass growth depending on biofilm thickness and stratification. The most loaded stratum in bacteria/biomass was the sewage-biofilm interface stratum that represented 51% of the total bacteria/biomass. Stirring rate and ionic strength of mono- and bivalent salts showed a major influence in biofilm disruption. The stirring time enhanced the exchange dynamic and matter capture between biofilm fragments at the critical stirring rate 90 r/min. Sodium chloride showed the dispersing effect on biofilms in suspension, and decreased the BOD5 （biochemical oxygen demand） beyond the physiological salt concentration.

关键词： biofilms, biochemical oxygen demand (BODs) chemical oxygen demand (COD) biomass ionic strength

Amenability and the Extension Property

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics 2014年第19期5卷 2945-2951页

作者： antoine Derighetti EPFL SB-DO MA A1 354 Station 8 CH-1015 Lausanne Switzerland

Let G be a locally compact group, H a closed amenable subgroup and u an element of the Herz Figà-Talamanca algebra of H with compact support, we prove the existence of an extension of u to G, with a good control of t... 详细信息

关键词： Convolution Operators Locally Compact Groups Abstract Harmonic Analysis Amenable Groups