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Anti-inflammatory and membrane stabilizing properties of methyl jasmonate in rats

Chinese Journal of Natural Medicines 2017年第3期15卷 202-209页

作者： UMUKORO Solomon ALABI Akinyinka Oladipo eDUVIeRe anthony Taghogho AJAYI Abidemi Mayowa OLUWOLe Oluwafemi Gabriel Department of Pharmacology and Therapeutics Faculty of Basic Medical Sciences University of lbadanIbadanNigeria Department of Pharmacology Faculty of Basic Medical SciencesOlabisi Onabanjo UniversityAgo-IwoyeNigeria Department of Pharmacology and Therapeutics College of Medicine and Health SciencesAfe Babalola UniversityAdo-Ekiti Nigeria

The present investigation was carried out to evaluate anti-inflammatory and membrane stabilizing properties of methyl jasmonate(MJ) in experimental rat models of acute and chronic *** effects of MJ on acute inflammation were assessed using carrageenan-induced rat's paw edema *** granuloma air pouch model was employed to evaluate the effects of MJ on chronic inflammation produced by carrageenan in *** number of white blood cells(WBC) in pouch exudates was estimated using light *** levels of biomarkers of oxidative stress,such as malondialdehyde(MDA),glutathione(GSH) and activity of antioxidant enzymes in the exudates,were determined using *** membrane stabilizing property of MJ was assessed based on inhibition of hemolysis of rat red blood cells(RBC) exposed to hypotonic *** results indicated that MJ(25-100 mg·kg-1,i.p.) produced significant anti-inflammatory activity in carrageenan-induced paw edema in rats(P educed the volume of pouch exudates and the number of WBC in carrageenan-induced granulomatous *** also exhibited potent antioxidant and membrane stabilizing *** conclusion,these findings suggest the therapeutic potentials of methyl jasmonate in disease conditions associated with inflammation and its anti-inflammatory activity may be related to its antioxidant and membrane stabilizing activities.

关键词： Methyl jasmonate Granuloma air pouch model Anti-inflammatory Antioxidant Membrane stabilizing property

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Flow fields and particle trajectories beneath a tidal bore:A numerical study

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International Journal of Sediment Research 2018年第3期33卷 351-370页

作者： Adrien Berchet Bruno Simon anthony Beaudoin Pierre Lubin Germain Rousseaux Serge Huberson Institut Pprime Université de Bordeaux

Tidal bores may appear in some estuaries when the tides quickly reach a high level. This phenomenon is rare but has a strong impact during its short duration: i.e. the river bed is significantly eroded and sediments are then transported. In this paper, the trajectories of suspended particles induced by this flow are numerically studied. Four undular bores with Froude numbers between 1.1 and 1.2 are *** similar Froude numbers, various initial flow conditions were selected to produce or not an inversion of the flow direction during the bore passage. The particle trajectories associated with each distinct flow configuration are presented and analyzed. These trajectories, estimated by solving the Maxey-Riley equation, appear to be very different even though the Froude numbers of flows are *** observations are important because the Froude number is often used to characterize a tidal bore as it describes well the free surface, however, it cannot describe the sediment transport. Finally, Chen’s model of wave-current interactions is adapted to fit the cases studied and is applied to the four bores simulated. The results highlight that this latter model can reproduce the observed trajectories and dissociate their different components. From this model, it is shown that the inertial and Basset history effects can be neglected compared to the gravity and flow entrainment effects due to the viscous drag when one wants to determine the long-term trajectories of suspended particles.

关键词： Tidal bores Sediment transport Trajectories Physical modeling Numerical modeling

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Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation

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Bone Research 2022年第4期10卷 826-837页

作者： Yugo Morita Motoo Saito Javier Rangel-Moreno anthony M.Franchini John R.Owen John C.Martinez John L.Daiss Karen L.de Mesy Bentley Stephen L.Kates edward M.Schwarz Gowrishankar Muthukrishnan Center for Musculoskeletal Research University of Rochester Medical CenterRochesterNYUSA Division of Allergy Immunology and RheumatologyDepartment of MedicineUniversity of Rochester Medical CenterRochesterNYUSA Department of environmental Medicine University of Rochester School of Medicine and DentistryRochesterNYUSA Department of Orthopedic Surgery Virginia Commonwealth UniversityRichmondVAUSA Department of Orthopedics University of Rochester Medical CenterRochesterNYUSA Department of Pathology and Laboratory Medicine University of Rochester Medical CenterRochesterNYUSA

Interleukin-27 is a pleiotropic cytokine whose functions during bacterial infections remain controversial,and its role in patients with *** osteomyelitis is *** address this knowledge gap,we completed a clinical study and observed elevated serum IL-27 levels(20-fold higher,Pents compared with healthy ***,IL-27 serum levels were 60-fold higher in patients immediately following septic death than in uninfected patients(Pesting a pathogenic role of *** test this hypothesis,we evaluated *** osteomyelitis in WT and IL-27Rα^(−/−)mice with and without exogenous IL27 induction by intramuscular injection of rAAV-IL-27p28 or rAAV-GFP,*** found that IL-27 was induced at the surgical site within 1 day of *** infection of bone and was expressed by M0,M1 and M2 macrophages and osteoblasts but not by ***,exogenous IL-27p28(~2 ng·mL^(−1) in serum)delivery ameliorated soft tissue abscesses and periimplant bone loss during infection,accompanied by enhanced local IL-27 expression,significant accumulation of RORγt^(+)neutrophils at the infection site,a decrease in RANK^(+) cells,and compromised osteoclast *** effects were not observed in IL-27Rα^(−/−)mice compared with WT mice,suggesting that IL-27 is dispensable for immunity but mediates redundant immune and bone cell functions during *** vitro studies and bulk RNA-seq of infected tibiae showed that IL-27 increased nos1,nos2,il17α,il17f,and rorc expression but did not directly stimulate ***,these results identify a novel phenomenon of IL-27 expression by osteoblasts immediately following *** infection of bone and suggest a protective role of systemic IL-27 in osteomyelitis.

关键词： abscess protective immunity

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Investigation of the torsional deformation of the complete upper denture: A pilot study

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Journal of Biomedical Science and engineering 2013年第4期6卷 443-448页

作者： anthony e. Prombonas Maria A. Paralika Nikolas A. Poulis Department of Dental Technology Technological and Educational Institute of Athens Athens Greece Department of Mechanical engineering and Civil Work Technological and Educational Institute of Athens Athens Greece

The aim of this research is to clarify whether the midline axis of the complete upper denture (CUD) is the axis of its torsion during loading, apart from the known bending deflection. Furthermore the present study is intended to estimate the influence of the anterior notches on the torsional deformation of the CUD. Using commercial edentulous molds and standardized procedures, six identical CUDs were fabricated with an initial fraenal notch of 5 mm. Two additional notch conditions were produced by deepening the notch to a total depth of 9 mm and by creating an incisal diastema of 7 mm. Five biaxial (also known as “fish bone”) strain gauges were cemented onto the palatal section of the dentures so that their middle axis coincided with the midline axis of the outer surface of the denture. For the denture specimen used in this study, the specific point of torsion was detected 2 cm from the point of contact of the two artificial central incisors. The presence of a deep fraenal notch and the combination of the deep fraenal notch with the presence of an incisal diastema increased the torsion of the CUD to a significant level (P = 0.006 and P = 0.05, respectively). It was shown that the midline can be the CUD’s axis of torsion. Biaxial strain gauges could be a reliable method of measuring the torsional deformation of the CUD.

关键词： Complete Upper Denture Torsional Deformation Biaxial Strain Gauge

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OFDM-WDM LR-PON with ultra-bendable fiber for last-mile distribution of quintuple-play service

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Chinese Optics Letters 2013年第8期11卷 18-23页

作者： Tiago M. F. Alves Rakesh Sambaraju Adolfo V. T. Cartaxo anthony Ng'oma Instituto de Telecomunicao es Department of Electrical and Computer Engineering Instituto Superior Tcnico Technical University of Lisbon1049-001 Lisbon Portugal Science and Technology Department Corning Incorporated One Riverfront PlazaCorning NY 14831 USA

The provision of quintuple-play services along wavelength division multiplexed （WDM） long-reach passive optical networks （LR-PONs） employing an ultra-bendable fiber in last-mile distribution is demonstrated experimentally. Particularly, the simultaneous transmission of three 100-GHz-spaced optical channels for the provision of double sideband orthogonal frequency-division multiplexing （OFDM） wireless and wired quintuple-play services to the premises of users located at 75, 85, and 100 km away from the central office is demonstrated. The OFDM-WDM LR-PON is tested considering the last-mile fiber distribution suffering from severe bending conditions without optical dispersion compensation. The experiments are performed for a worst last-mile fiber bending case emulated by considering a Corning ClearCurve fiber experiencing 20 bends and a bend radius of 7.5 mm. All the OFDM signals received at the premises of users present error vector magnitude （eVM） levels compliant with the eVM thresholds of the corresponding standards. An eVM degradation in the OFDM signals received by each user not exceeding 0.8 dB due to the last-mile distribution fiber is achieved.

关键词： WDM PON OFDM-WDM LR-PON with ultra-bendable fiber for last-mile distribution of quintuple-play service LR

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基于红外相机数据评估华南地区豹猫的种群密度和活动节律

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生物多样性 2022年第9期30卷 89-99页

作者：杨剑焕李敬华杨浩炫欧梓键郑玺 anthony J.Giordano 陈辈乐嘉道理农场暨植物园中国香港999077 Society for the Preservation of endangered Carnivores&Their International ecological Study VenturaCA 93006USA

可靠的种群密度数据对野生动物的保护和管理十分重要。豹猫(Prionailurus bengalensis)是中国分布最广且常见的猫科动物,但野生种群密度估算的研究并不多。本研究于2020年6月至2021年5月在香港新界嘉道理农场暨植物园开展红外相机调查,... 详细信息

可靠的种群密度数据对野生动物的保护和管理十分重要。豹猫(Prionailurus bengalensis)是中国分布最广且常见的猫科动物,但野生种群密度估算的研究并不多。本研究于2020年6月至2021年5月在香港新界嘉道理农场暨植物园开展红外相机调查,利用空间标记-重捕法估算当地豹猫的种群密度并用核密度估计方法分析其活动节律。本次调查以网格方式布置红外相机,在约1.5 km^(2)的研究范围之内设置了19个相机位点,每个位点安装2台相机以获取豹猫身体两侧花纹来进行个体识别。连续12个月调查共捕获113次有效的豹猫拍摄事件,当中仅61次事件的照片足够清晰以进行个体识别。基于种群封闭的要求,我们以2个月为单位将12个月的数据分为6个采样期去分析豹猫种群密度,结果显示仅两个采样期的估算值最为准确,分别为0.64±0.31(0.26–1.55)只/km^(2)和0.87±0.48(0.31–2.40)只/km^(2),是已知全球豹猫密度最高的地点之一。结果还发现,雨季研究地点的豹猫并无明显的日活动节律,在旱季则偏夜行-晨昏行性多一些,但也有一定的日间活动;雨季和旱季的日活动节律无显著差异。本研究是首次以个体识别配以空间标记-重捕模型对中国大陆地区豹猫种群密度调查的研究;我们也提出一些关于红外相机架设方法的建议,以提高照片个体识别的准确度并增加重捕次数,最后提高密度估算的准确度。本研究也进一步证明豹猫适应性极强,在活动节律上表现出极高的可塑性,在严格保护下可以恢复健康的种群。

关键词：空间标记-重捕模型种群密度活动节律相机陷阱小型猫科动物食肉目香港

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Size matters: wintering ducks stay longer and use fewer habitats on largest Chinese lakes

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Avian Research 2019年第4期10卷 415-422页

作者： Fanjuan Meng Hongbin Li Xin Wang Lei Fang Xianghuang Li Lei Cao anthony David Fox State Key Laboratory of Urban and Regional ecology Research Center for Eco‑Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China School of Life Sciences University of Science and Technology of ChinaHefei 230026China Department of Bioscience Aarhus UniversityAarhusDenmark

Background:evidence suggests that wintering waterbirds have become conspicuously more concentrated at two largest lakes of the Yangtze River Floodplain,east Dong Ting Lake(Hunan Province,29°20′N,113°e)and Poyang Lake(Jiangxi Province,29°N,116°20′e),relative to other lakes,despite the establishment of reserves *** this relationship is likely due to greater extent of undisturbed habitats in larger lakes,we understand little of the drivers affecting individual behaviours behind this ***:We tracked wintering movements of three duck species(eurasian Wigeon Mareca penelope,Falcated Duck *** and Northern Pintail Anas acuta)using GPS transmitters,examining differences between the two largest lakes and other smaller lakes in ducks’habitat use,duration of stay at each lake and the daily distances moved by the tagged birds while at these ***:The eurasian Wigeon and Falcated Duck stayed five times longer and almost exclusively used natural habitat types at the two large lakes(91‒95%of positions)compared to length of stay time at smaller lakes,where they spent 28‒33 days on average(excluding the capture site)and exploited many more different habitats(including c.50%outside lakes).Conclusions:Our study is the first to show that shorter length of stay and more varied habitat use by ducks at small lakes may contribute to explaining the apparent regional concentration of numbers present of these and other species at the largest lakes in recent *** compares with their declining abundance at smaller lakes,where habitat loss and degradation has been more manifest than on the larger lakes.

关键词： Anas acuta GPS/GSM telemetry Mareca falcata Mareca penelope Winter residency time Yangtze River Floodplain

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Wintering Swan Geese maximize energy intake through substrate foraging depth when feeding on buried Vallisneria natans tubers

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Avian Research 2019年第2期10卷 163-170页

作者： Yan Chen Yong Zhang Lei Cao Willem F.de Boer anthony D.Fox School of Life Sciences University of Science and Technology of ChinaHefei 230027China Co-Innovation Center for Sustainable Forestry in Southern China College of Biology and the EnvironmentNanjing Forestry UniversityNanjing 210037China Research Center for eco-environmental Science Chinese Academic of Sciences18 Shuangqing RoadBeijing 100085China University of Chinese Academy of Sciences 19 Yuquan RoadShijingshan DistrictBeijing 100049China Resource ecology Group Wageningen UniversityDroevendaalsesteeg3a6708 PB WageningenThe Netherlands Department of Bioscience Aarhus UniversityKalφGrenavej 148410 RφndeDenmark

Background: Foraging theory predicts that animals select patches that offer the highest net rate of energy gain. Hence, prey distribution patterns and spatiotemporal heterogeneity play important roles in determining animal feeding patch selection. For waterfowl foraging on buried aquatic plant tubers, the distribution and biomass of these plant organs vary with depth in the substrate. Since excavation costs also increase with depth, the energy intake of the animals foraging on these plants is highly sediment depth dependent. Methods: Here, using observations of Swan Geese (Anser cygnoides) foraging on Vallisneria natans tubers, we test our hypothesis that geese feeding on tubers buried at intermediate sediment depth maximize their daily energy intake because of the interaction between tuber size and abundance with depth. To do this, we measured the distribution patterns of buried Vallisneria tubers under both undisturbed conditions and post-exploitation by geese (i.e. giving-up conditions). We investigated the relationship between tuber size and burial depth, and total tuber biomass within each sediment layer in undisturbed and exploited plots. Finally, we compared modelled Swan Goose daily energy intake feeding on Vallisneria tubers buried at different sediment layers (1–10, 11–20 and 21–30 cm below the surface). Results: Dry weight of Vallisneria tubers linearly increased with burial depth, while average total dry weight density of tubers showed a unimodal relationship, peaking at intermediate levels. Not surprisingly, Swan Geese foraged most intensively on tubers buried at intermediate sediment depths, where they maximize their daily energy intake. Our results support our hypothesis that Swan Geese feeding on tubers at intermediate depths maximize their daily energy intake. Conclusions: Our study is the first to quantify foraging strategies of Swan Geese during the wintering period, emphasizing the importance of plant traits on foraging selection of belowground f

关键词： energetic trade-off Optimal foraging Shengjin Lake Substrate Tuber burial depth Yangtze River

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Flood Mitigation Parameters of Apiti Wetlands Soil in a Segment of Mamu River Basin, Nigeria

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Journal of environmental Protection 2015年第2期6卷 129-137页

作者： Nkiru A. ezenwaji emma e. ezenwaji anthony C. Okoye Department of Zoology Nnamdi Azikiwe University Awka Nigeria Department of Geography and Meteorology Nnamdi Azikiwe University Awka Nigeria Department of environmental Management Nnamdi Azikiwe University Awka Nigeria

Wetlands are essential components of our global ecosystem. They have important functions which include maintenance of the environment through mitigating the degree of flooding, regulating the local and global climate and lessening the degree of erosion by trapping sediments. The aim of this research is therefore to investigate how relevant wetland parameters mitigate flood in Apiti wetland soil of middle River Mamu basin of Nigeria. For the purpose of the study, the wetland was divided into three;A (the upland region), B (the flood plain), and C (the raffia palm area). The soil flood mitigation parameters examined are bulk weight, moisture content, and saturation water content. These were employed to calculate the volume of flood mitigation within three sub-sites of the wetland. The statistical methods employed were One Way ANOVA and Students t-Test to see whether differences occur in the flood mitigating ability of the soil. Results obtained show that flood mitigation was highest within study site B (flood plain) with 6.4 × 106 m3 volume of flood mitigation and lowest in site A (upland region) with 1.5 × 106 m3. In conclusion we recommended that the study be scaled up to other wetlands in Nigeria.

关键词： Component Apiti Basin Flood Mitigation Wetland

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Freestanding hierarchical porous carbon film derived from hybrid nanocellulose for high-power supercapacitors

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Nano Research 2017年第5期10卷 1847-1860页

作者： Zhi Li Kaveh Ahadi Keren Jiang Behzad Ahvazi Peng Li anthony O. Anyia Ken Cadien Thomas Thundat Chemical and Materials engineering University of Alberta Edmonton Alberta T6G 2V4 Canada Biomass Conversion & Processing Technologies InnoTech Alberta Innovates-Technology Futures Edmonton Alberta T6N 1E4 Canada nanoFAB University of Alberta Edmonton Alberta T6G 2V4 Canada National Research Council of Canada 100 Sussex Drive Ottawa Ontario K1A OR6 Canada

Nanocellulose is a sustainable and eco-friendly nanomaterial derived from renewable biomass. In this study, we utilized the structural advantages of two types of nanocellulose and fabricated freestanding carbonized hybrid nanocellulose films as electrode materials for supercapacitors. The long cellulose nanofibrils （CNFs） formed a macroporous framework, and the short cellulose nanocrystals were assembled around the CNF framework and generated micro/mesopores. This two-level hierarchical porous structure was successfully preserved during carbonization because of a thin atomic layer deposited （ALD） A1203 conformal coating, which effectively prevented the aggregation of nanocellulose. These carbonized, partially graphitized nanocellulose fibers were interconnected, forming an integrated and highly conductive network with a large specific surface area of 1,244 m2·g-1. The two-level hierarchical porous structure facilitated fast ion transport in the film. When tested as an electrode material with a high mass loading of 4 mg·cm-2 for supercapacitors, the hierarchical porous carbon film derived from hybrid nanocellulose exhibited a specific capacitance of 170 F·g-1 and extraordinary performance at high current densities. even at a very high current of 50 A-g-l, it retained 65% of its original specific capacitance, which makes it a promising electrode material for high-power applications.

关键词： nanocellulose supercapacitors hierarchical structure atomic layer deposition(ALD) integrated structure

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