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Systematic review of noninvasive treatments to arrest dentin non-cavitated caries lesions

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World Journal of Clinical Cases 2014年第5期2卷 137-141页

作者： Isauremi Vieira de Assun??o Giovanna de Fátima alves da Costa Boniek Castillo Dutra Borges Department of Dentistry Federal University of Rio Grande do NorteNatal59056-000Brazil

AIM: To systematically review the literature on the efficacy of noninvasive methods of arresting the progression of non-cavitated occlusal carious lesions in ***: The Medline/Pub Med,LILACS,Sci ELO and Scopus databases were searched to identify relevant publications through to November *** clinical trials evaluating the ability of noninvasive methods to arrest the progression of occlusal non-cavitated carious lesions in dentin were ***,data extraction and quality assessment were conducted independently and in ***: Of 167 citations identified,nine full text articles were screened and five were included in the *** papers reported on occlusal fissure sealing using a self-curing glass ionomer(n = 1) or resin-based(n = 4) *** the use of resin-based sealant to obliterate occlusal fissures arrested the progression of non-cavitated occlusal carious lesions in ***: Occlusal fissure sealing with a resin-based sealant may arrest the progression of non-cavitated occlusal dentinal *** clinical trials with longer follow-up times should be performed to increase scientific evidence.

关键词： Dentin Dental caries Fissure sealants Preventive therapy Dental restoration

Non-Hodgkin’s Lymphoma Associated with Metastatic Lung Cancer: Case Report

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Advances in Lung Cancer 2021年第3期10卷 40-47页

作者： Miriam Viviane Baron Gabriela Di Lorenzo Garcia Scherer Célia Regina Martins Korzenieski Julia Braga da Silveira Carolina Boeira Soares Carina Marangoni Marcus Vinicius de Mello Pinto Aline Ronis Sampaio Alexandre Gomes Sancho Esteban Fortuny Pacheco Felice Picariello Joice Nedel Ott Isabel Cristina Reinheimer Carolina gonçalves Pinheiro Nathália Ken Pereira Iketani Cristine Brandenburg Danielle de Mello Florentino Patrícia Froes Meyer Bartira Ercília Pinheiro da Costa Postgraduate Program in Medicine and Health Sciences of the Pontifical Catholic University of Rio Grande do Sul (PUC/RS) Porto Alegre Brazil School of Medicine of the Pontifical Catholic University of Rio Grande do Sul (PUC/RS) Porto Alegre Brazil School of Health and Life Sciences of the Pontifical Catholic University of Rio Grande do Sul (PUC/RS) Porto Alegre Brazil Celulare Institute Rio de Janeiro Brazil Unigranrio Rio de Janeiro Brazil Universidad Finis Terrae Santiago Chile Università degli Studi di Napoli Federico II Napoli Italy Postgraduate Program in Health Sciences of the Faculty of Medicine of ABC (FMABC) S&#227 o Paulo Brazil Hospital Beneficiente Portuguesa of Belém Pará Brazil Federal University of Ceará (UFC) Fortaleza Brazil Uniredentor University Rio de Janeiro Brazil Centro Universitário do Rio Grande do Norte Natal RN Brazil

Lymphomas are neoplastic transformations that affect lymphoid cells. Diffuse large B-cell non-Hodgkin’s lymphoma has a high degree of cell proliferation, accounting for 30% of all lymphomas. Lung cancer is the leading cause of death worldwide and the recommended treatment is chemotherapy. Among the main complications resulting from non-Hodgkin’s lymphoma, lung cancer and chemotherapy used in their treatment, we can mention sepsis, acute kidney injury and febrile neutropenia. Febrile neutropenia can occur by suppressing the production of neutrophils. Sepsis, a widespread infection, is the main cause of acute kidney injury, which can also be caused by hydroelectrolytic complications or by nephrotoxicity. This is a report of a smoking patient with metastatic lung cancer who sought care due to progressive dysphagia, cough with chest pain, fever, and lower airways critical obstruction due to mediastinal lymphadenopathy, being diagnosed with diffuse large B-cell non-Hodgkin’s lymphoma. The patient evolved to death because of a significant worsening of the ventilatory pattern of multifactorial cause, mainly due to sepsis, acute kidney injury, and febrile neutropenia. The patient had mostly classic characteristics of her comorbidities, however, the overlapping of interrelated comorbidities led to the outcome of death. What is unusual about the present case report is that the patient’s characteristics, such as age, sex, and ethnicity, are opposite to those described as risk factors for diffuse large B-cell non-Hodgkin’s lymphoma.

关键词： Acute Kidney Injury Febrile Neutropenia Sepsis Chemotherapy

Early Hepatic Encephalopathy after a Transjugular Intrahepatic Portosystemic Shunt Procedure: Case Report

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Open Journal of Gastroenterology 2021年第6期11卷 81-88页

作者： Miriam Viviane Baron Gabriela Di Lorenzo Garcia Scherer Michele Paula dos Santos Andres Felipe Mantilla Santamaria Cristine Brandenburg Isabel Cristina Reinheimer Marcus Vinicius de Mello Pinto Aline Ronis Sampaio Alexandre Gomes Sancho Alexandre Gomes Sancho Esteban Fortuny Pacheco Felice Picariello Danielle de Mello Florentino Joice Nedel Ott Carolina gonçalves Pinheiro Nathália Ken Pereira Iketani Sonia Carvalho Patrícia Froes Meyer Bartira Ercília Pinheiro da Costa Postgraduate Program in Medicine and Health Sciences of the Pontifical Catholic University of Rio Grande do Sul (PUC/RS) Porto Alegre Rio Grande do Sul Brazil School of Medicine of the Pontifical Catholic University of Rio Grande do Sul (PUC/RS) Porto Alegre Rio Grande do Sul Brazil Industrial University of Santander (UIS) Bucaramanga Colombia University of Vale do Acaraú (IDJ/UVA) Ceará Brazil Celulare Institute Rio de Janeiro Brazil Unigranrio Rio de Janeiro Brazil Universidad Finis Terrae Santiago Chile Università degli Studi di Napoli Federico II Napoli Italy Uniredentor University Rio de Janeiro Brazil Postgraduate Program in Health Sciences of the Faculty of Medicine of ABC (FABC) S&#227o Paulo Brazil Hospital Beneficiente Portuguesa of Belém Pará Brazil Rigshospital Copenhagen East K&#248benhavn Denmark Centro Universitário do Rio Grande do Norte Natal Brazil

Patients with decompensated hepatic cirrhosis may present systemic alterations and dysfunction of multiple organs. Ascites, portal hypertension, esophageal varices, and hepatic encephalopathy are common complications arising from cirrhosis. The aim of this paper is to report a case of a patient with liver cirrhosis and the complications of a transjugular intrahepatic portosystemic shunt. Male, elderly, and ex-alcoholic, diagnosed with liver cirrhosis, ascites, and esophageal varices. He underwent transjugular intrahepatic portosystemic shunt due to portal hypertension and returned to the hospital after 24 hours with agitation and mental confusion. He had a bowel movement stop, neurological worsening, loss of renal function, hepatic hydrothorax, hepatic encephalopathy, hypernatremia, hypocalcemia, and hypophosphatemia. He underwent a new procedure to occlude the transjugular intrahepatic portosystemic shunt, showing improvement of the mental status and ascites. However, continued with decompensation and hydro-electrolytic disorders. He evolved with worsening of the ventilatory pattern, and neurological and renal function, with a fatal outcome. Esophageal varices due to portal hypertension can be corrected with the transjugular intrahepatic portosystemic shunt. However, complications such as hypernatremia, hepatic hydrothorax, and hepatic encephalopathy may occur. Therefore, there is a need for reintervention to shunt or reduce its caliber. Thus, for patients with advanced age and decompensated cirrhosis, the potential risks and benefits of this procedure should be carefully evaluated due to the risk of complications and death.

关键词： Ascites Hypernatremia Portasystemic Shunt Transjugular Intrahepatic Hepatic Encephalopathy

High-power non-perturbative laser delivery diagnostics at the final focus of 100-TW-class laser pulses

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High Power Laser Science and Engineering 2021年第2期9卷 174-183页

作者： Fumika Isono Jeroen van Tilborg Samuel K.Barber Joseph natal Curtis Berger Hai-En Tsai Tobias Ostermayr anthony gonsalves Cameron Geddes Eric Esarey Lawrence Berkeley National Laboratory BerkeleyCAUSA University of California BerkeleyCAUSA

Controlling the delivery of multi-terawatt and petawatt laser pulses to final focus,both in position and angle,is critical to many laser applications such as optical guiding,laser–plasma acceleration,and laser-produced secondary *** present an online,non-destructive laser diagnostic,capable of measuring the transverse position and pointing angle at *** diagnostic is based on a unique double-surface-coated wedged-mirror design for the final steering optic in the laser line,producing a witness beam highly correlated with the main *** propagating low-power kilohertz pulses to focus,we observed spectra of focus position and pointing angle fluctuations dominated by frequencies below 70 *** setup was also used to characterize the excellent position and pointing angle correlation of the 1 Hz high-power laser pulses to this low-power kilohertz pulse train,opening a promising path to fast non-perturbative feedback concepts even on few-hertz-class high-power laser systems.

关键词： high-power lasers laser diagnostics laser stabilization

用Rifabutin治疗近期诊断的肺结核:该药对利福平的多国随机比较性研究

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国际结核病与肺部疾病杂志 1996年第3期 99-106页

作者： L.J.gonzalez-Montaner S.natal P.Yongchaiyud P.Olliaro the Rifabutin Study Group 李荣德 Division of Phthisiopeumonology Hospital MunizBuenos AiresArgentina Campanha Nacional Contra a Tuberculose Rio de JaneiroBrazil Department of Medicine Siriaj HospitalBangkokThailand Farmitalia Carlo Erba MilanItaly

背景:在阿根廷、巴西、泰国的6个中心征集到的新近诊断、对药物敏感、X线片活动、经细菌学证实的肺结核病人。目标:评价两个含有不同每日剂量的rifabufin的用药方案与利福平的功效、耐受性和毒性的比较。设计:多中心、随机、比较性研究... 详细信息

背景:在阿根廷、巴西、泰国的6个中心征集到的新近诊断、对药物敏感、X线片活动、经细菌学证实的肺结核病人。目标:评价两个含有不同每日剂量的rifabufin的用药方案与利福平的功效、耐受性和毒性的比较。设计:多中心、随机、比较性研究。在各组中,研究药物均为每日服用,共6个月,搭配异烟肼(6个月),和吡嗪酰胺与乙胺丁醇(二者均为2个月后停药)。治疗成功的病人被追踪观察长达2年。结果:登记参加病人共520名,随机分别接受利福平(n=175),或rifabutin 150mg(n=174)或rifabutin 300mg(n=171)。在全部基线培养阳性病人中,利福平、rifabutin150mg和rifabutin 300mg各组每一病人最后一次有效观察时治疗成功率分别为89％、94％和92％。三个组培养阴转所需时间的中值具可比性,利福平为34天,两个rifabutin组均为37天。在停药观察期间,利福平组1例复发,两个rifabutin组各有2例复发。三种治疗方案似皆能被很好地耐受。rifabutin 150mg组中,无一例因不良反应而需停止治疗,与之相比,利福平组中有1例,rifabutin 300mg组中有5例发生此种情况。结论:三种给药方案都证明有效,且能很好耐受。Rifabutin每日150mg表明有最佳风险收益比,因该组完成治疗的病人比率最高,细菌阴转率最高,而不良反应发生率最低。

关键词：比较性研究不良反应细菌学追踪观察耐受性治疗方案药物敏感利福平成功率泰国

前苏联远东南部的中生代增生楔地体及增生方式

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世界地质 1993年第1期 85-85页

作者： B.A natal'in 陈华

中生代增生楔地体在其大洋与大陆边缘源岩石的年代和岩性,在泥砾混杂堆积与混杂岩基质的年代以及在构造特点诸方面都有差别。它们的分布及其与岩浆岩弧的可能关系、对古动物、古植物残迹的古地理分析、对碰撞变形作用及区域构造分带的... 详细信息

中生代增生楔地体在其大洋与大陆边缘源岩石的年代和岩性,在泥砾混杂堆积与混杂岩基质的年代以及在构造特点诸方面都有差别。它们的分布及其与岩浆岩弧的可能关系、对古动物、古植物残迹的古地理分析、对碰撞变形作用及区域构造分带的分析等都是确定中生代增生方式的基础。 Tukuringra-Dzhagdinsk(TD),Galamak(GL)和Ulbansk(UL)地体都是增生楔,它们是由古生代至中侏罗世向西伯利亚板块南缘的俯冲作用产生的。俯冲作用的消失是由

关键词：中生代大陆边缘中生界地质年代大洋边缘地体增生楔斜向碰撞

Health, Aging and Quality of Life: An Evaluation of Experience in Family Health Unit through Popular Education

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Health 2014年第15期6卷 1959-1963页

作者： Cristina Katya Torres Teixeira Mendes Fabia Barbosa de Andrade Danielle Nóbrega de Castro Maria do Socorro Feitosa alves Gilson de Vasconcelos Torres Maria Adelaide Paredes Moreira antonia Oliveira Silva Department of Dentistry Federal University of Rio Grande do Norte Natal Brazil Department of Nursing FACISA Federal University of Rio Grande do Norte Natal Brazil Department of Nursing Federal University of Rio Grande do Norte Natal Brazil Department of Public Health and Psychiatry Federal University of Paraíba Jo&atilde o Pessoa Brazil Municipal Health Joã o Pessoa Paraíba Brazil Nursing Federal University of Paraíba Jo&atilde o Pessoa Brazil Nursing Federal University of Rio Grande do Norte Natal Brazil

This study aims to assess the implementation of the Health, Aging and Quality of Life. The specific objectives were executed by conducting activities with the elderly through generative themes with an emphasis on health, aging and quality of life;evaluation of the experience of older people in Unity Family Health with Popular Education;analyzing the evolution of indicators of health and quality of life of elderly patients after two years and ascertaining the effectiveness of Popular Education in the elderly group in the Family Health Unit. This is an exploratory study approved by the Ethics and Research Committee UFPB/CCS, number 0598/08 held on Primary Health Care. The project consists of two lines of integrated activities: Group Active Ageing (GEA), which brings together seniors for addressing issues related to healthy aging and the Multidimensional Health Assessment and Quality of Life through the WHOQOL-BREF. The activities were built in fortnightly meetings from the dialogue where experiences are shared and collective needs. Thus, relevant topics were suggested for the group: guidelines on physical activity, nutrition, chronic disease prevention, self-esteem, among others, and group dynamics as body stretching, stretching exercises, respiratory, metabolic and relaxation. The observed results are the very satisfactions group, reported through testimonies and translated by the enthusiasm and diligence in participation. This project promoted a better bio-psycho-social development of the elderly, reinforcing its identity by promoting and facilitating the expression of their potential positive and arousing them to a better future life prospects and community socialization feelings.

关键词： Health Aging Quality of Life

Comparative Study of Collagen Stimulation Using Semi-Ablative and Non-Ablative Radiofrequency

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Journal of Biosciences and Medicines 2022年第6期10卷 79-89页

作者： Patrícia Froes Meyer Rodrigo Marcel Valentim da Silva Eneida De Morais Carreiro Rafaella Rêgo Maia Stephany Luanna Queiroga Farias Ciro Dantas Soares Yuri Alexander Afonso Gustavo Felipe Pasqual Silene Bazi Ribeiro Roberto Tiago alves Pinheiro University Centre of Rio Grande do Norte (UNIRN) Natal Brazil Estácio de Sá University Natal Brazil Federal University of Rio Grande do Norte Natal Brazil Potiguar University (UNP) Natal Brazil Campinas State University (UNICAMP) Campinas Brazil Brazilian Society of Plastic Surgery Brazil FSG University Centre of Serra Gaúcha Caxias do Sul Brazil MARC Institute Miami USA

Objective: Comparison between semi-ablative and non-ablative radiofrequency for collagen stimulation. Method: Three volunteers with scheduled surgical procedures of abdominoplasty were selected. After the evaluation, the abdominal area was divided into three quadrants, with the right region receiving monopolar non-ablative radiofrequency (RF) application. In contrast, the left region received fractionated radiofrequency (FRF) application, using three different needle sizes (0.5, 1.5, and 3.0 mm), and the intermediate area was kept as a control. After 24 hours, surgery was performed, and the skin flaps were collected for histological and immunohistochemical analyses. Results: An increase in total collagen and type I collagen was observed in the treated groups. There was also an increase in the expression of COX-2, CD68 positive cells (macrophages), and lymphocyte markers (CD3, CD20, and NK-CD57). Furthermore, it was seen that only the use of 3.0-mm needles kept the channels open in the superficial tissue after 24 hours. There were no significant differences between the modalities. Conclusion: Non-ablative and sub-ablative radiofrequency have positive and effective results for flaccidity, demonstrating the success in collagen production. Furthermore, this study is the first to present channel opening and permanence time, which are important to optimize the action of drug delivery.

关键词： Collagen Flaccidity Radiofrequency Drug Delivery

On the Impact of Brazil's Largest Recent Oil Spill on Regional Oceans

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Sustainable Marine Structures 2021年第2期3卷 1-14页

作者： Liana de Figueiredo Mendes Patricia Pinheiro Beck Eichler Tatiana Leite Ana Beatriz alves Bennemann Clara de Souza Melo Andressa Lima Ferreira Khalil Bow Ltaif Garcia Luzia Liniane do Nascimento Silva Christofer Paul Barker Helenice Vital Moab Praxedes Gomes Priscila F.M.Lopes Department of Ecology Federal University of Rio Grande do Norte(UFRN)University CampusLagoa Nova59072-970 NatalRNBrazil Graduate Program in Geodynamics and Geophysics(PPGG) Laboratory of Marine Geology and Geophysics and Environmental MonitoringFederal University of Rio Grande do Norte 0JFRN)University CamposLagoa Nova59072-970 NatalRNBrazil ***(California USA) Department of Ecology and Zoology Federal University of Santa CatarinaTrindade88040-900FlorianopolisSCBrazil

In 2019,an oil spill in Brazil,of unknown origin,severely impacted coastal environs with the worst environmental disaster ever recorded in any tropical coastal region globally severely damaging South Pirangi Reef area in the state of Rio Grande do Norte(RN).Here we discuss acute and chronic impacts including chemical contamination and economic consequences all over the world and show some evidence of the oil spill in this biodiverse ***,the lapse between the moment of the disastei;and the action to manage it,was hampered by a political agenda coinciding with local and global tragedies that redirected public *** almost 2 years have passed still without the offending party identification or culpability;and poor communities may continue to absorb its deleterious impacts for decades without consideration or *** disaster occurred during the Brazilian government's current issues involving extensive environmental mismanagement,resulting in a slow response from an inept *** is with urgent necessity to spotlight this tragedy in this unique and sensitive reef habitat experiencing the ongoing damaging effects that include socio-economic losses not yet addressed.

关键词： Environmental impacts Socioeconomic losses Government Brazilian coast Oil spill Disaster