检索结果-南通市图书馆

Aza-BODIPY dye with unexpected bromination and high singlet oxygen quantum yield for photoacoustic imaging-guided synergetic photodynamic/photothermal therapy

引用

Chinese Chemical Letters 2024年第6期35卷 445-450页

作者： Leichen Wang anqing mei Na Li Xiaohong Ruan Xu Sun Yu Cai Jinjun Shao Xiaochen Dong Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(IAM) Nanjing Tech University(NanjingTech)Nanjing 211800China School of Chemistry&Materials Science Jiangsu Normal UniversityXuzhou 221116China Center for Rehabilitation Medicine Rehabilitation&Sports Medicine Research Institute of Zhejiang ProvinceDepartment of Rehabilitation MedicineZhejiang Provincial People’s Hospital(Affiliated People’s HospitalHangzhou Medical College)Hangzhou 310014China

Introducing heavy halogen atoms into organic small molecules is a practical strategy for efficient singlet oxygen(^(1)O_(2))***,bromine or iodine atoms are introduced on the aza-borondipyrromethene(aza-BODIPY)core,rather than on the periphery aryl rings for efficient~1O_(2) ***,an aza-BODIPY dye NBDPBr with unexpected bromination on the periphery aryl rings was synthesized for photoacoustic(PA)imaging-guided synergistic photothermal therapy(PTT)and photodynamic therapy(PDT)in tumor *** to unexcepted bromination at the periphery aryl rings,NBDPBr demonstrated an outstanding singlet oxygen quantum yield(Φ_(Δ))of 66% which was superior to similar brominated photosensitizers previously *** encapsulation with amphiphilic polymer F-127,hydrophilic NBDPBr nanoparticles(NPs)were fabricated and exhibited an excellent photothermal conversion efficiency(η)of 43.0% under 660 nm *** vivo PA imaging results demonstrated that NBDPBr NPs could specifically accumulate at tumor sites and realized the maximum tumor retention at 7 h *** the in vitro and in vivo results indicated the significant potence of NBDPBr with unexpected bis-bromination for PA imaging-guided synergetic PDT/PTT.

关键词： Unexpected bromination Aza-BODIPY Photodynamic therapy Photothermal therapy Synergetic therapy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

DYNAMIC CHARACTERISTICS OF LIQUID SLOSHING IN A RECTANGULAR TANK UNDER LOW GRAVITY

引用

Journal of Hydrodynamics 2006年第2期18卷 170-176页

作者： CHENG Xu-duo HU mei-zhu LIU Zhi-yun School of Food Science and Engineering Nanjing University of Finance and Economics Nanjing 210003 China Department of Physics Anqing Teachers College Anqing 246011 China School of Food Science and Engineering Nanjing University of Finance and Economics Nanjing 210003 China

In this paper, the dynamics of liquid sloshing in a rectangular tank under low gravity was investigated. The basic frequencies and the velocity potentials of sloshing of liquid were obtained by expansion of the Fourier series. The characteristics of force and moment of the liquid acting on a rectangular tank were analyzed. The equivalent mechanical models of spring-vibrator-damper of sloshing of liquid were established with mechanical equivalent principle and numerical results were given. The numerical results show that the equivalent sloshing mass increases with the increase of gravity, and that the basic frequency and the equivalent sloshing mass increase with the increase of the liquid depth.

关键词： low gravity liquid sloshing equivalent mechanical model

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

THE EQUIVALENT MECHANICAL MODELS OF LIQUID SLOSHING IN A SPHERICAL TANK WITH SPACER UNDER LOW GRAVITY

引用

Journal of Hydrodynamics 2005年第1期17卷 110-116页

作者： CHENGXu-duo HUmei-zhu WENJi-hua SchoolofFoodScienceandEngineering NanjingUniversityofFinanceandEconomics.Nanjing210003China／／DepartmentofPhysicsAnqingTeachersCollegeAnqing246011China SchoolofFoodScienceandEngineering NanjingUniversityofFinanceandEconomicsNanjing210003China

The dynamics of liquid sloshing in a spherical tank with spacer under low gravity was investigated. By extending the characteristic functions, the frequencies of liquid free sloshing, reaction force and moments on the wall of tank were obtained. By mechanical equivalent principle, the equivalent models of spring vibrator damper of liquid sloshing were given. The numerical results obtained show when a spacer is inserted in the tank, the sloshing frequency of liquid and the sloshing mass of liquid will decrease.

关键词： low gravity liquid sloshing equivalent mechanical models

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Identification of Mulberry Bacterial Blight Caused by Klebsiella oxytoca in Bazhong,Sichuan,China

引用

Phyton-International Journal of Experimental Botany 2024年第8期93卷 1995-2008页

作者： Yuan Huang Jia Wei Peigang Liu Yan Zhu Tianbao Lin Zhiqiang Lv Yijun Li mei Zong Yun Zhou Junshan Gao Zilong Xu School of Life Science Anhui Agricultural UniversityHefei230036China Institute of Sericulture and Tea Zhejiang Academy of Agricultural SciencesHangzhou310021China School of Life Science Anqing Normal UniversityAnqing246133China

To provide a scientific basis for controlling mulberry bacterial blight in Bazhong,Sichuan,China(BSC),this study aimed to isolate and purify pathogenic bacteria from diseased branches of mulberry trees in the region and to clarify their taxonomic status using morphological observation,physiological and biochemical detection,molecular-level identification,and the construction of a phylogenetic tree.A total of 218 bacterial strains were isolated from samples of diseased mulberry *** these,7 strains were identified as pathogenic bacteria based on pathogenicity tests conducted in accordance with Koch’s *** findings from the analysis of the 16S rRNA sequence indicated that the 7 pathogenic bacteria are members of Klebsiella *** observation revealed that the pathogenic bacteria were oval-shaped and had capsules but no *** could secrete pectinase,cellulase,and protease and were able to utilize D-glucose,D-mannose,D-maltose,and *** 7 strains of pathogenic bacteria exhibited the highest homology with Klebsiella *** study identifies Klebsiella oxytoca as the causative agent of mulberry bacterial blight in BSC,laying the foundation for the prevention and control of this pathogen and further investigation into its pathogenic mechanism.

关键词： Mulberry bacterial blight pathogenic identiﬁcation Klebsiella spp. Klebsiella oxytoca

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

DYNAMIC CHARACTERISTICS OF LIQUID SLOSHING IN A TRANSVERSELY VIBRATING SPHERICAL TANK WITH A SPACER UNDER LOW GRAVITY

引用

Journal of Hydrodynamics 2008年第6期20卷 762-769页

作者： CHENG Xu-duo HU mei-zhu WEN Ji-hua School of Food Science and Engineering Nanjing University of Finance and Economics Nanjing 210003 China Department of Physics Anqing Teachers College Anqing 246011 China

The dynamic characteristics of liquid sloshing in a transversely vibrating spherical tank with spacer under low gravity were investigated. By expanding the characteristic functions, the frequencies and velocity potentials of liquid free-sloshing were obtained. The dynamic equations and boundary conditions of liquid sloshing in the traverse vibrational spherical tank with spacer under low gravity were derived. By modifying the velocity potentials of liquid free-sloshing, the velocity potentials of liquid sloshing in the traverse vibrating spherical tank with a spacer were obtained. Furthermore, the forces and the moments acting on tank wall were given. The numerical results show when a spacer is inserted in the tank, the sloshing frequencies of liquid and the forces acting on tank wall will decrease, but the moment of force to the centre of the tank which is caused by the force of liquid acting on the spacer will occur.

关键词： low gravity liquid forced sloshing sloshing suppression

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

黄梅戏中的安庆官话研究

引用

语言研究 2024年第3期44卷 102-108页

作者：宋瑾陈淑梅黄冈师范学院音乐学院湖北黄冈438000 黄冈师范学院文学院湖北黄冈438000

黄梅戏起源于湖北黄梅的采茶歌,是清朝道光年间在鄂、皖、赣三省毗邻地区形成的一种民间小戏。其中一支逐渐东移到安徽省怀宁县为中心的安庆地区,其语言基调是黄梅方言,又受到安庆方言和民歌的渗透,形成了独具特色的语言——黄梅戏官话... 详细信息

黄梅戏起源于湖北黄梅的采茶歌,是清朝道光年间在鄂、皖、赣三省毗邻地区形成的一种民间小戏。其中一支逐渐东移到安徽省怀宁县为中心的安庆地区,其语言基调是黄梅方言,又受到安庆方言和民歌的渗透,形成了独具特色的语言——黄梅戏官话。黄梅戏官话在语音、词语、语法等方面很有特色,与黄梅方言不完全相同,与安庆方言存在着一定的差异。黄梅戏官话可助力黄梅戏的传承,黄梅戏是保护安庆官话重要途径。文章提出地方戏曲和方言保护的新路径:通过地方戏曲的传播来保护地方方言,通过地方方言来助力地方戏曲的发展。

关键词：黄梅戏地方戏曲安庆官话方言唱词声腔

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

DYNAMIC CHARACTERISTICS OF LIQUID FORCED SLOSHING IN A TURNING SPHERICAL TANK WITH A SPACER UNDER LOW GRAVITY

引用

Journal of Hydrodynamics 2008年第2期20卷 202-209页

作者： CHENG Xu-duo HU mei-zhu WEN Ji-hua School of Food Science and Engineering Nanjing University of Finance and Economics Nanjing 210003China Department of Physics Anqing Teachers College Anging 246011 China

Under the condition of low gravity the characteristics of liquid forced sloshing in a turning spherical tank with a spacer were investigated. The static shape of the liquid surface was analyzed. By expanding the characteristic functions, the frequencies and velocity potential of liquid free-sloshing were derived. The governing equations and boundary conditions for the forced sloshing of liquid under the tank turning were established. The transverse force of liquid acting on the tank and the moment of force to the centre of the tank which is caused by the force of liquid acting on the spacer were given. Numerical results were compared with the ones of the spherical tank without a spacer. The results show that when a spacer is inserted in the tank, the sloshing frequency of liquid and the transverse force of liquid acting on the tank will decrease, but the moment of force to the centre of the tank which is caused by the force of liquid acting on the spacer will occur.

关键词： low gravity forced sloshing of liquid sloshing suppression

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

华佗文化记忆的媒介呈现与建构

引用

安庆师范大学学报（社会科学版） 2024年第3期43卷 36-44页

作者：孙文马梅亳州学院中文与传媒系安徽亳州236800 安徽师范大学新闻与传播学院安徽芜湖241000

安徽亳州是我国著名的“四大药都”之一,也是“神医”华佗的故乡,当地民众对华佗文化记忆拥有独特的文化基因。媒介对集体记忆具有呈现、延续和强化的作用,立足亳州本土文化,对当地民众华佗文化记忆的媒介呈现方式进行探究,深入讨论了... 详细信息

安徽亳州是我国著名的“四大药都”之一,也是“神医”华佗的故乡,当地民众对华佗文化记忆拥有独特的文化基因。媒介对集体记忆具有呈现、延续和强化的作用,立足亳州本土文化,对当地民众华佗文化记忆的媒介呈现方式进行探究,深入讨论了社交媒介对集体记忆建构与传播过程中所带来的记忆创伤和“信息疲惫”等影响,尝试为如何延续和强化当地民众的华佗文化记忆,聚力共建“世界中医药之都”,提供支撑与参考。

关键词：华佗集体记忆中医药文化媒介建构

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于A-ECMS的增程式电动汽车能量管理策略设计及应用

引用

安庆师范大学学报（自然科学版） 2024年第2期30卷 47-51页

作者：张光洲梅琳合肥学院先进制造工程学院安徽合肥230601

增程式电动汽车因其电驱效率高、无里程焦虑等优点,在新能源汽车市场备受青睐。为了进一步提升其综合性能,本研究在MATLAB/Simulink环境下构建了增程式电动汽车仿真模型,并利用等效自适应因子以改进燃油消耗最小化算法,形成了基于A-ECM... 详细信息

增程式电动汽车因其电驱效率高、无里程焦虑等优点,在新能源汽车市场备受青睐。为了进一步提升其综合性能,本研究在MATLAB/Simulink环境下构建了增程式电动汽车仿真模型,并利用等效自适应因子以改进燃油消耗最小化算法,形成了基于A-ECMS的能量管理策略。结果表明,在WLTC循环工况测试中,A-ECMS能量管理策略的百公里综合油耗为6.42 L,综合燃油消耗量为0.71 L,均低于其他方法。最终的电池充电状态(SOC)为31.1%,与目标SOC的偏差仅为1.1%。该策略显著提升了燃油经济性和电池使用寿命,为增程式电动汽车性能优化提供了新的参考方法。

关键词：增程式电动汽车能量管理策略设计 ECMS

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

初治HER2阳性乳腺癌患者新辅助治疗后达tpCR的预测模型构建

引用

中国普外基础与临床杂志 2024年第4期31卷 455-459页

作者：邵佳梅林夏明林海军安庆医院肿瘤科安徽安庆246000

目的探讨初治人表皮生长因子受体2(human epidermal growth factor receptor 2,HER2)阳性乳腺癌患者新辅助治疗后达完全病理完全缓解(total pathological complete response,tpCR)的影响因素,旨在为手术方案制定及预后评估提供更多参考... 详细信息

目的探讨初治人表皮生长因子受体2(human epidermal growth factor receptor 2,HER2)阳性乳腺癌患者新辅助治疗后达完全病理完全缓解(total pathological complete response,tpCR)的影响因素,旨在为手术方案制定及预后评估提供更多参考。方法回顾性纳入2021年1月至2023年1月于海军安庆医院接受新辅助治疗的95例初治HER2阳性乳腺癌患者的临床资料,采用多因素logistic回归模型探索初治HER2阳性乳腺癌患者新辅助治疗后达tpCR的影响因素。结果95例患者新辅助治疗后达tpCR 51例,未达tpCR 44例。多因素logistic回归模型分析结果显示,HER23+(OR=6.102,P=0.014)、分子分型为HER2+/激素受体–(HER2+/激素受体+OR=0.129,P=0.006)及采用曲妥珠单抗+帕妥珠单抗方案(OR=6.582,P=0.014)者的tpCR率更高,雌激素受体3+(OR=0.122,P=0.033)、孕激素受体3+(OR=0.179,P=0.020)、Ki-67指数为15%~30%(OR=0.088,P=0.030)和31%~60%(OR=0.066,P=0.017)者的tpCR率较低。该模型的预测曲线下面积为0.881[95%CI(0.815,0.947)]。结论初治HER2阳性乳腺癌患者新辅助治疗后达tpCR与免疫组织化学HER2表达水平、分子分型、新辅助靶向治疗方案等有关,同时基于这些影响因素构建的预测模型能够一定程度预测患者新辅助治疗后的tpCR效果。

关键词：乳腺癌完全病理完全缓解人表皮生长因子受体2 阳性表达新辅助治疗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：