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基于Fe3O4@AuNPs/MWCNTs-COOH纳米免疫传感器快速测定水产品的呋喃它酮代谢产物

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食品科学 2025年第2期46卷 222-230页

作者：李亭何欢歌鲁航李书国河北科技大学食品与生物学院河北石家庄050018

采用磁性四氧化三铁(Fe3O4)、纳米金(gold nanoparticles,AuNPs)、羧基化多壁碳纳米管(carboxylated multi-walled carbon nanotubes,MWCNTs-COOH)复合纳米材料固定化呋喃它酮代谢产物3-氨基-5-多酚甲基-2-恶唑烷酮(3-amino-5-methylmorpholino-2-oxazolidinone,AMOZ)抗体制备磁性纳米免疫传感器,建立一种快速检测水产品中呋喃它酮代谢产物的方法。利用紫外-可见光谱和红外光谱技术对制备的纳米Fe3O4和纳米复合材料Fe3O4@AuNPs的结构进行分析,利用扫描电子显微镜和透射电子显微镜对纳米材料的微观形貌进行表征;运用循环伏安法、电化学交流阻抗法对传感器的电化学性能进行表征,以[Fe(CN)6]^(3-/4-)为探针,用微分脉冲伏安法对实验条件进行优化,优化结果如下:Fe3O4@AuNPs和MWCNTs-COOH体积比为1∶2,电解质溶液pH值为7.0,抗体质量浓度为80μg/mL,孵育温度为37℃,孵育时间为30 min。在此条件下,该免疫响应电流与lg C[AMOZ]在1.0×10^(-10)~8.0×10^(-7)mol/L范围内具有良好的线性关系,检出限为2.4×10^(-11)mol/L,在鲫鱼样品实际检测中,加标回收率为92.78%~102.61%,与高效液相色谱-串联质谱法检测结果基本一致,但该法具有前处理简便、检测速度快的优势,可用于实际水产品中呋喃它酮代谢产物AMOZ的快速检测。

关键词：食品安全呋喃它酮代谢产物纳米免疫传感器水产品快速检测

双相障碍患者的风险决策偏好:来自三水平元分析的证据

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心理学报 2025年第1期57卷 100-124,I0001-I0010页

作者：陆嘉琦李雨斯何贵兵浙江大学心理与行为科学系杭州310058 杭州师范大学经亨颐教育学院杭州311121

本研究采用三水平元分析定量估计双相患者与健康个体的风险决策偏好差异,并检验该差异是否受到样本特征和测量特征的调节。基于71篇文献和176个效应量的元分析发现,双相患者比健康个体更偏好风险寻求(Hedges'g=0.301),且这一偏好在风险... 详细信息

本研究采用三水平元分析定量估计双相患者与健康个体的风险决策偏好差异,并检验该差异是否受到样本特征和测量特征的调节。基于71篇文献和176个效应量的元分析发现,双相患者比健康个体更偏好风险寻求(Hedges'g=0.301),且这一偏好在风险态度量表(Hedges'g=0.624)、行为实验任务(Hedges'g=0.252)和日常风险行为(Hedges'g=0.312)中都稳定存在。同时,该差异还受到年龄(β=0.009)和心境阶段的调节,其中不论心境阶段如何,双相患者均比健康个体更偏好风险寻求(缓解期:Hedges'g=0.245;躁狂期:Hedges'g=0.604;重性抑郁期:Hedges'g=0.417)。此外,在行为实验任务中,该差异受到年龄(β=0.012)和地区的调节。特别是欧洲(Hedges'g=0.419)和南美洲(Hedges'g=0.420)的患者,以及在爱荷华赌博任务(Hedges'g=0.396)和剑桥赌博任务(Hedges'g=0.220)中的患者,均比健康个体更偏好风险寻求;而在日常态度和行为中,该差异仅受到心境阶段的调节,躁狂期患者(Hedges'g=0.747)比健康个体更偏好风险寻求。本研究首次通过多种风险决策偏好测量类型探讨双相障碍与风险决策的关系,得出了较稳定的结果,并提出未来研究应充分考虑心境阶段、任务类型等因素的影响,深入挖掘双相障碍影响风险决策的心理机制,为双相障碍的临床管理和心理教育提供参考。

关键词：双相障碍风险决策元分析决策范式跨心境特异性

A novel flexible nerve guidance conduit promotes nerve regeneration while providing excellent mechanical properties

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Neural Regeneration Research 2025年第7期20卷 2084-2094页

作者： Tong Li Quhan Cheng Jingai Zhang Boxin Liu Yu Shi Haoxue Wang Lijie Huang Su Zhang Ruixin Zhang Song Wang Guangxu lu Peifu Tang Zhongyang Liu Kai Wang Department of Orthopedics the Fourth Medical Center of Chinese PLA General HospitalBeijingChina Department of Training and Sports Medicine Characteristic Medical Center of Chinese People’s Armed Police ForceTianjinChina Medical School of Chinese PLA BeijingChina Key Laboratory of Bioactive Materials for the Ministry of Education College of Life SciencesNankai UniversityTianjinChina Department of Orthopedics Tianjin HospitalTianjinChina Department of Rehabilitation Medicine Er Quan Hospital of PAPWuxiJiangsu ProvinceChina

Autografting is the gold standard for surgical repair of nerve defects>5 mm in length;however,autografting is associated with potential complications at the nerve donor *** an alternative,nerve guidance conduits may be *** ideal conduit should be flexible,resistant to kinks and lumen collapse,and provide physical cues to guide nerve *** designed a novel flexible conduit using electrospinning technology to create fibers on the innermost surface of the nerve guidance conduit and employed melt spinning to align ***,we prepared disordered electrospun fibers outside the aligned fibers and helical melt-spun fibers on the outer wall of the electrospun fiber *** presence of aligned fibers on the inner surface can promote the extension of nerve cells along the *** helical melt-spun fibers on the outer surface can enhance resistance to kinking and compression and provide *** novel conduit promoted nerve regeneration and functional recovery in a rat sciatic nerve defect model,suggesting that it has potential for clinical use in human nerve injuries.

关键词： aligned fibers anti-kinking helical fibers nerve guidance conduit nerve regeneration peripheral nerve injury topological guidance

Role of nutrition in diabetes mellitus and infections

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World Journal of Clinical Cases 2025年第3期13卷 1-8页

作者： Xue-lu Yu Li-Yun Zhou Xiao Huang Xin-Yue Li Ming-Ke Wang Ji-Shun Yang Naval Medical Center of PLA Naval Medical UniversityShanghai 200052China

In this editorial,we have commented on the article that has been published in the recent issue of World Journal of Clinical *** authors have described a case of unilateral thyroid cyst and have opined that the acute onset of infection may be linked to diabetes mellitus(DM).We have focused on the role of nutrition in the association between DM and *** with DM are at a high risk of infection,which could also be attributed to nutrition-related *** interventions for patients with diabetes are mainly based on a low-calorie diet,which can be achieved by adhering to a low-carbohydrate ***,dietary fiber supplementation is recommended to maintain the diversity of the gut ***,high-quality protein can prevent the increased risk of infection due to *** of vitamins C,vitamins A,vitamins D,and folic acid improves blood sugar control and facilitates immune *** deficiencies augment the risk of infection,but the relationship with diabetes is mostly U-shaped and a good intake should be maintained.

关键词： Diabetes mellitus Infection Macronutrients Vitamins Minerals

Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

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Traditional Medicine Research 2025年第2期10卷 1-15页

作者： Xu Liang Ni-Hui Zhang Zhi-Lai Zhan Guang-lu Chang Yan Gao Xia Li Wen-Yuan Gao School of Pharmaceutical Science and Technology Faculty of MedicineTianjin UniversityTianjin 300193China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300402China

Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon

关键词： Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics chemometrics multiple component quantification quality evaluation

社会福利水平与资源消耗耦合协调的时空演化及驱动因素

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生态经济 2025年第1期41卷 185-194页

作者：王璐方行明成都大学马克思主义学院四川成都610100 西南财经大学中国西部经济研究院四川成都611100

基于2004—2020年中国省级面板数据,通过构建耦合协调度模型测算社会福利水平与资源消耗之间的协调程度。然后,构建空间杜宾模型实证检验两者耦合协调发展的驱动机制并对各驱动因素的空间效应进行分解。研究结果显示:(1)研究期间内,中... 详细信息

基于2004—2020年中国省级面板数据,通过构建耦合协调度模型测算社会福利水平与资源消耗之间的协调程度。然后,构建空间杜宾模型实证检验两者耦合协调发展的驱动机制并对各驱动因素的空间效应进行分解。研究结果显示:(1)研究期间内,中国社会福利水平与资源消耗之间的耦合协调度整体呈上升趋势,仅个别年份存在回落现象;西部地区耦合协调度低于东、中部地区,而中部地区后来居上,于2017年反超东部地区;上海、北京耦合协调度一直处于领先水平,天津2015年后耦合协调度递减明显。(2)经济规模、产业结构、技术进步、能源消费结构、能源强度、外商投资以及政府规模显著驱动社会福利水平与资源消耗耦合协调发展。(3)社会福利水平与资源消耗耦合协调发展的过程中对周边地区存在正向空间溢出效应,各驱动因素对耦合协调度的影响也存在空间溢出效应。其中,产业结构、技术进步与能源消费结构的直接效应与间接效应方向相反。

关键词：社会福利水平资源消耗耦合协调度驱动因素空间效应分解

2022年泸定6.8级地震房屋震害及其统计分析

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地震研究 2025年第1期48卷 123-131页

作者：孙路刘金龙湖州职业技术学院建筑工程学院浙江湖州313000 湖州市绿色建筑技术重点实验室浙江湖州313000 中国地震局工程力学研究所中国地震局地震工程与工程振动重点实验室黑龙江哈尔滨150080

2022年四川省甘孜州泸定县发生6.8级地震。依据现场调查资料,介绍了震区房屋的主要结构类型及其建造特点,总结了各类房屋结构的典型震害现象,探讨了各类房屋典型震害特征的产生机理。通过震害数据的统计分析,建立了本次地震中各类结构... 详细信息

2022年四川省甘孜州泸定县发生6.8级地震。依据现场调查资料,介绍了震区房屋的主要结构类型及其建造特点,总结了各类房屋结构的典型震害现象,探讨了各类房屋典型震害特征的产生机理。通过震害数据的统计分析,建立了本次地震中各类结构房屋的震害矩阵,并与其他学者的研究成果进行了对比,研究了不同房屋类型各地震破坏等级分布规律,给出了砖混结构房屋的地震易损性曲线。根据本次地震的震害特点,给出了提升房屋抗震能力的建议。

关键词：泸定6.8级地震房屋震害抗震能力

数字赋能乡村公共文化事业高质量发展——以乡村图书馆建设为例

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三峡大学学报（人文社会科学版） 2025年第1期47卷 65-71页

作者：卢迪曲阜师范大学马克思主义学院山东济宁273100

数字赋能乡村公共文化事业高质量发展是全面推进乡村振兴战略的基本要求,也是逐步实现人民群众精神文化生活共同富裕的题中之义。乡村图书馆是乡村公共文化服务体系的重要组成部分,在数字赋能过程中要以民需导向的服务理念、技术支撑的... 详细信息

数字赋能乡村公共文化事业高质量发展是全面推进乡村振兴战略的基本要求,也是逐步实现人民群众精神文化生活共同富裕的题中之义。乡村图书馆是乡村公共文化服务体系的重要组成部分,在数字赋能过程中要以民需导向的服务理念、技术支撑的转型升级、人文铸魂的角色定位、数字乡村的建设助力作为建设的数智图景,同时在基础设施、智慧人才、数字素养、长效机制等方面存在着发展的现实梗阻。因此,在数字赋能乡村图书馆建设过程中要从推进数字化基础设施建设、加强智慧人才的人力储备、全方位提升乡村数字素养、优化数字转型的顶层设计这四个方面入手。

关键词：数字赋能乡村公共文化乡村图书馆

Lipomatous ependymoma with ZFTA:RELA fusion-positive:A case report

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World Journal of Clinical Cases 2025年第1期13卷 48-55页

作者： Xiao-Yu Zhao Juan-Han Yu Yi-Hua Wang Yi-Xin Liu lu Xu Lin Fu Ning Yi China Medical University The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Pathology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Anshan Cancer Hospital Anshan 114000Liaoning ProvinceChina

BACKGROUND Ependymoma with lipomatous differentiation is a rare type of *** ZFTA fusion-positive supratentorial ependymoma is a novel tumor type in the 2021 World Health Organization classification of central nervous system *** fusion-positive lipomatous ependymoma has not been reported to *** SUMMARY We reported a case of a 15-year-old Chinese male who had a sudden convulsion lasting approximately six *** resonance imaging showed a round cystic shadow of approximately 1.9 cm×1.5 cm×1.9 cm under the right parieto-occipital *** examination showed characteristic perivascular pseudorosettes and adipose differentiation in the ***-chemical staining showed that the tumor cells were negative for cytokeratin,NeuN,Syn and p53,but positive for GFAP,vimentin and S-100 ***-ficant punctate intracytoplasmic EMA immunoreactivity was *** level of Ki-67 was about 5%.Genetic analysis revealed ZFTA:RELA fusion.A cranio-tomy with total excision of the tumor was *** follow-up time was 36 months,no evidence of disease recurrence was found in magnetic resonance *** Based on these findings,the patient was diagnosed as a ependymoma with ZFTA fusion and lipomatous *** case report provides information on the microscopic morphological features of ependymoma with ZFTA fusion and lipomatous differentiation,which can help pathologists to make a definitive diagnosis of this tumor.

关键词： Ependymoma Lipomatous Molecular classification Supratentorial ZFTA:RELA fusion Case report