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Squamous Cell Carcinoma of the Middle Ear Mimicking CSOM with Intracranial Complications: A Diagnostic Dilemma

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International Journal of Otolaryngology and Head & Neck Surgery 2014年第6期3卷 376-381页

作者： anoop attakkil Vandana Thorawade Mohan Jagade Rajesh Kar Kartik Parelkar Poonam Khairnar Reshma Hanowate Devkumar Rangaraja Department of ENT Grant Medical College & Sir J.J. Hospital Mumbai India

Cancer of the external auditory canal (EAC) and middle ear (ME) is rare, accounting for less than 1% of all head-and-neck malignancies [1] [2] of which squamous cell carcinoma (SCC) is the most common. Even though squamous cell carcinoma [SCC] of the middle ear and chronic suppurative otitis media (CSOM) co-exist, no definitive correlation has been proven. Here we are presenting a case of squamous cell carcinoma of the middle ear who presented with headache, fever and vomiting with a background history of chronic suppurative otitis media since childhood. A provisional diagnosis of mastoid abscess with intracranial complications secondary to chronic suppurative otitis me dia was made and modified radical mastoidectomy was done but histology of the mastoid specimen revealed well differentiated keratinizing squamous cell carcinoma, which was treated with radical radiotherapy. Objective of this presentation is to bring attention to the coexistence of CSOM and squamous cell carcinoma ear and also the importance to detect these lesions at an early stage. This report also highlights the requirement of histopathological analysis in mastoidectomy and discusses the aetiology and management of squamous cell carcinoma of the middle ear with review of literature.

关键词： Squamous Cell Carcinoma Mastoid Otitis Media

Tracheal Leiomyoma: A Rare Entity &Role of Diode Laser in Its Management

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International Journal of Otolaryngology and Head & Neck Surgery 2014年第4期3卷 143-148页

作者： anoop attakkil Vandana Thorawade Mohan Jagade Rajesh Kar Kartik Parelkar Dnyaneswar Rohe Rohini Kashide Poonam Khairnar Department of ENT Grant Medical College & Sir J.J. Hospital Mumbai India

Primary leiomyoma of the trachea is a rare disease which is of smooth muscle in origin. Presenting symptoms depend on the location and size of the tumor. Here we are presenting a 45-year-old female, who was misdiagnosed and being treated for bronchial asthma presented to our institution with stridor. Her x-ray and Computed Tomography of neck showed tracheal mass & biopsy reported leiomyoma. Objective of this presentation is to report tracheal leiomyoma which is a rare clinical entity and how endoscopic resection of the tumor with diode laser helped us in attaining complete resection of tumor with minimal intra-operative and post-operative complications.

关键词： Leiomyoma Diode Laser Trachea

Chondroma of Tongue: A Rare Case Report &Review of Literature

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International Journal of Otolaryngology and Head & Neck Surgery 2014年第6期3卷 359-363页

作者： anoop attakkil Vandana Thorawade Mohan Jagade Rajesh Kar Kartik Parelkar Dnyaneswar Rohe Poonam Khairnar Reshma Hanowate Department of ENT Grant Medical College & Sir J.J. Hospital Mumbai India

Chondromas are common benign cartilaginous tumours in the skeletal system usually found in extremities. Extra skeletal chondromas are relatively uncommon of which those in head and neck regions are rarely documented. Although the tongue is one of the most common sites of oral soft tissue chondroma, lingual chondromas are rare as evidenced by the fact that only 33 cases are identified in the review of literature till now. This report has the objective of presenting a rare case of lingual enchondroma in a 26-year-old male which was excised with no evidence of recovery during follow up. We have also tried to present a concise review of the relevant literature.

关键词： Soft Tissue Chondroma Tongue

Our Experience with Embryonal Rhabdomyosarcoma Presenting as Aural Polyp

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International Journal of Otolaryngology and Head & Neck Surgery 2015年第1期4卷 1-5页

作者： anoop attakkil Vandana Thorawade Mohan Jagade Rajesh Kar Dnyaneswar Rohe Reshma Hanowate Devkumar Rangaraja Kartik Parelkar Department of ENT Grant Medical College & Sir J.J. Hospital Mumbai India

Aural polyps are a common clinical entity encountered by otorhinolaryngologist in daily practice. Polyps are frequently seen in paediatric patients, usually inflammatory in nature. In children rhabdomyosarcomas (RMS) can mimic all the cinical features of chronic suppurative otitis media which usually present as external auditory canal mass or polyp. Here we present a case where a male child presented with recurrence of polyp in left ear which was finally diagnosed as embryonal rhabdomyosarcoma which is a rare and invariably fatal disease in children. Through this article we intend to highlight the failures and delay committed in attaining diagnosis in this patient in spite of multispecialty evaluation involving repeated imaging and histopathological correlation. Our experience with embryonal rhabdomyosarcoma throws light on the high vigilance required in handling the aural polyps in pediatric population as early diagnosis and treatment are the key elements for successful outcomes.

关键词： Embryonal Rhabdomyosarcoma Aural Polyp CSOM

An Unusal Case of Epidermal Cyst in Submandibular Space

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International Journal of Otolaryngology and Head & Neck Surgery 2014年第5期3卷 213-215页

作者： Rajesh Kar Vandana Thorawade Mohan Jagade anoop attakkil Shubhangi Kedar Dnyaneshwar Rohe Kartik Parelkar Rajanala Nataraj Devkumar Rengaraja Department of ENT & Head & Neck Surgery Grant Government Medical College & Sir J.J. Group of Hospitals Mumbai India

Epidermal cysts are very common skin lesions and 1.6% are seen in oral cavity. But epidermal cyst in submandibular region is extremely rare with only 3 such reported cases in last 25 years. Here we present a rare case... 详细信息

关键词： Epidermal Cyst Submandibular Space Epidermoid Cyst

ESTIMATION OF A SUBSET OF REGRESSION COEFFICIENTS OF INTEREST IN A MODEL WITH NON-SPHERICAL DISTURBANCES

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Journal of Systems Science & Complexity 2013年第2期26卷 209-231页

作者： CHATURVEDI anoop KESARWANI Suchita Department of Statistics University of Allahabad

This paper considers the estimation of a subset of regression coefficients in a linear regression model with non-spherical disturbances,when other regression coefficients are of no interest.A family of estimators is considered and its asymptotic distribution is *** proposed family of improved estimators is compared with the usual unrestricted FGLS estimator,and dominance conditions are obtained with respect to risk under quadratic loss as well as the Pitman nearness *** results of a numerical simulation are presented to illustrate the risk performance of various estimators.

关键词： Large sample asymptotic minimum mean square error non-spherical disturbances pitman nearness criterion quadratic loss risk.

Tackling imbalanced data in cybersecurity with transfer learning: a case with ROP payload detection

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Cybersecurity 2023年第2期6卷 29-43页

作者： Haizhou Wang anoop Singhal Peng Liu College of Information Sciences and Technology The Pennsylvania State UniversityState CollegeUSA The National Institute of Standards and Technology GaithersburgUSA

In recent years,deep learning gained proliferating popularity in the cybersecurity application domain,since when being compared to traditional machine learning methods,it usually involves less human efforts,produces better results,and provides better ***,the imbalanced data issue is very common in cybersecurity,which can substantially deteriorate the performance of the deep learning *** paper introduces a transfer learning based method to tackle the imbalanced data issue in cybersecurity using return-oriented programming payload detection as a case *** achieved 0.0290 average false positive rate,0.9705 average F1 score and 0.9521 average detection rate on 3 different target domain programs using 2 different source domain programs,with 0 benign training data sample in the target *** performance improvement compared to the baseline is a trade-off between false positive rate and detection *** our approach,the total number of false positives is reduced by 23.16%,and as a trade-off,the number of detected malicious samples decreases by 0.68%.

关键词： Domain adaptation Return-oriented programming Imbalanced dataset

Climate change detection and attribution in the Ganga-Brahmaputra-Meghna river basins

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Geoscience Frontiers 2021年第5期12卷 192-201页

作者： Chetan Sharma anoop Kumar Shukla Yongqiang Zhang Civil Engineering Department JIETJodhpurRajasthanIndia Key Laboratory of Water Cycle and Related Land Surface Processes Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China

Ganga-Brahmaputra-Meghna(GBM)river basin is the third-largest and one of the most populated river basins in the *** climate change is affecting most of the hydrometeorological variables across the globe,this study investigated the existence of climate change signal in all four climatological seasons in the GBM river basin and assessed the contribution of anthropogenic activities,i.e.,Greenhouse Gases(GHGs)emission in the *** decreasing trends in the monsoon and a small increase in pre-monsoon precipitation were *** change was detected in post-monsoon and winter season ***5 GCMs were used for climate change detection,change point estimation,and attribution *** Vector Machine(SVM)regression method was adopted to downscale GCM variables at the local ***-Carlo simulation approach was used to detect changes in different *** climate change‘signals’were detectable after the year 1980 using Signal to Noise ratio(SNR)method in the majority of central and north-western *** change point was detectable only in annual monsoon precipitation at the basin *** analysis indicated>50%contribution of anthropogenic activities(GHGs)to annual monsoon precipitation ***,there is high confidence that monsoon precipitation in GBM has significantly changed due to anthropogenic *** mitigation and adaption measures are also suggested,which may be adopted to manage the growing demand and water availability in the basin.

关键词： Ganga-Brahmaputra-Meghna(GBM) Climate change Support vector machine Signal to noise ratio Anthropogenic activities

AN INVESTIGATION OF TURBULENT RECTANGULAR JET DISCHARGED INTO A NARROW CHANNEL WEAK CROSSFLOW

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Journal of Hydrodynamics 2008年第2期20卷 154-163页

作者： PATHAK Manabendra DASS anoop K. DEWAN Anupam Department of Mechanical Engineering Indian Institute of Technology Guwahati Guwahati - 781039 India

A computational investigation of the mean flow field of turbulent rectangular jets issuing into a narrow channel crossflow is presented. The length of the jet slot spans more than 55% of the crossflow channel bed, leaving a small clearance between the jet edge and sidewalls. A finite volume code employing the standard k-εmodel is used to predict the mean, three-dimensional flow field. The mean flow field is investigated for two velocity ratios （6 and 9）. Important flow features, such as the formation of different vortical structures and their characteristics owing to different values of the velocity ratio, are discussed. Some predicted results are compared with the experimental data reported in the literature. The predicted mean and turbulent flow properties are shown to be in good agreement with the experimental data.

关键词： turbulent jet crossflow narrow charmel velocity ratio vortices