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Prediction of the seismic behavior of an underground railway station and a tunnel in Napoli(Italy)

Underground Space 2017年第2期2卷 88-105页

作者： S.Fabozzi V.Licata S.Autuori e.Bilotta G.Russo F.Silvestri University of Napoli Federico II NapoliItaly

The assessment of the seismic safety of underground structures,either tunnels or large station boxes,should not be overlooked especially in densely populated areas,even with low to moderate *** underground structures,an important issue is the estimation of the seismic actions acting on the structure;only few experimental evidences are available for multi-level propped *** tunnels,it is generally assumed that their seismic behavior in soft ground is governed by the surrounding soil,while the inertial load contribution of the underground structure itself is *** both cases,recent numerical studies proved that advanced dynamic analyses can provide satisfactory interpretation of non-linear soil-structure interaction during *** this paper,a real case study,represented by a large open multi-propped excavation and a circular segmented tunnel in a densely urbanized area of the city center in Napoli,has been used to investigate some of the mentioned *** geotechnical characterization and choice of the reference input motions lead to a first estimate of the free-field ground motion,which was subsequently used for pseudo-static decoupled *** the complexity of both excavation geometry and staged construction,a full dynamic analysis was considered neither affordable nor reliable for the multi-propped station box;thus two conventional pseudo-static analyses,applying either a displacement-based or a force-based approach,were carried *** the case of the tunnel,the seismic increments of internal forces in the lining could be calculated through both a simplified pseudostatic analysis and a full dynamic analysis,showing a satisfying ***,the results of the study demonstrated that the seismic increments of internal forces in the diaphragm walls of the station and in the segmented lining of the tunnel were quite *** case study encourages improving the reliability of simplified methods based on the more

关键词： Underground structures Tunnels Diaphragm walls Seismic behavior Pseudo-static analysis Dynamic analysis Soil-Structure interaction

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Verification of the 2019 GloSea5 Seasonal Tropical Cyclone Landfall Forecast for east China

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Journal of Meteorological Research 2020年第5期34卷 917-925页

作者： Joanne CAMP Philip e.BeTT Nicola GOLDING Chris D.HeWITT Timothy D.MITCHeLL Adam A.SCAIFe Met Office Hadley Centre Exeter EX 13PBUK University of Southern Queensland Toowoomba QLD 4350Australia College of engineering Mathematics and Physical SciencesUniversity of ExeterDevon EX44QFUK

A prototype climate service was developed and trialled in early 2019 to provide seasonal forecast of the June–July–August(JJA) tropical cyclone(TC) landfall risk for the east China region ahead of the forthcoming typhoon *** forecasts were produced in both March and April 2019 and a final forecast was released to the China Meteorological Administration(CMA) on 1 May 2019. The trial service was produced by using the Met Office Global Seasonal forecast system(GloSea5), and a forecast of the western Pacific subtropical high(WPSH) index was used to infer the TC landfall risk based on a simple linear regression between historical model WPSH indices and observed TC landfalls in east China. The forecast method shows significant skill for forecasting the JJA TC landfall risk in east China with up to three-month lead time, with the greatest skill for predictions initialized in May. The 2019 forecast provided good guidance of the near-average TC activity observed in east China in JJA 2019. Success of the forecast adds confidence to an improved climate service ahead of the 2020 typhoon season.

关键词： seasonal forecasting typhoons tropical cyclones(TCs) landfall risk east China western Pacific subtropical high(WPSH)

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Probable benign paroxysmal positional vertigo, spontaneously resolved:Incidence in medical practice, patients’ characteristics and the natural course

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Journal of Otology 2019年第3期14卷 111-116页

作者： M.G.Alvarez-Morujo de Sande R. Gonzalez-Aguado G. Guerra-Jimenez e. Domenech-Vadillo H. Galera-Ruiz e. Figuerola-Massana A. Ramos-Macías C. Morales-Angulo A.J. Martín-Mateos e. Domínguez-Duran Hospital Universitario Puerta del Mar Cadiz Spain Hospital Universitario Marques de Valdecilla Santander Spain Complejo Hospitalario Universitario Insular Materno-Infantil Las Palmas de Gran Canaria Spain Hospital Universitari Joan XXIII Tarragona Spain Hospital Infanta Luisa Sevilla Spain

Background: Probable benign paroxysmal positional vertigo, spontaneously resolved (pBPPVsr), is a variant of benign paroxysmal positional vertigo (BPPV) in which there is no observable nystagmus and no vertigo with any positional maneuver. Objectives: To calculate the incidence pBPPVsr, compare the characteristics of the patients with pBPPVsr and BPPV not spontaneously resolved and describe the spontaneous resolution in the natural course of BPPV. Methods: Multicenter prospective descriptive study. During a one-year period, all patients with suspected BPPV that presented to the Neurotology Units of five participating centers were recruited. The incidence of pBPPVsr was calculated as a percentage of the total number of patients with BPPV. The prevalence of several variables was compared between pBPPVsr and BPPV not spontaneously resolved. The timing of spontaneous resolution was estimated using Kaplan-Meier curves. Results: 457 patients met the inclusion criteria. The incidence of pBPPVsr was 33.5%. It was significantly higher in males, in patients with normal bone mass and in patients who were not taking sulpiride. A rate of 18% of spontaneous resolution after the first month and 51% after the first year was found. This percentage did not change in a significant way after this moment. The curves for males, patients under 50 and patients with normal blood pressure decreased significantly faster. Conclusions: In our serie, BPPV spontaneously resolved in half of the patients with BPPV during the first year. This seemed to occur more commonly in males and could have been hindered by sulpiride intake, osteoporosis, advanced age and high blood pressure.

关键词： Benign paroxysmal positional vertigo Probable benign paroxysmal positional vertigo, spontaneously resolved Osteoporosis Sulpiride Hypertension

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Ti Coating on Magnesium Alloy by Arc-Added Glow Discharge Plasma Penetrating Technique

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材料热处理学报 2004年第05B期25卷 684-687页

作者： CUICai-e MIAOQiang PANJun-de ZHANGPing-ze ZHANGGao-hui ResearchInstituteofSurfaceengineering TaiyuanUniversityofTechnologyTaiyuan030024China ResearchInstituteofSurfaceengineering TaiyuanUniversityofTechnologyTaiyuan030024China／／No.2ResearchInstituteofChinaElectronicsTechnologyGroupCorporationTaiyuan030024China

Arc-added glow discharge plasma penetrating technique is a new surface coating method. With the help of vacuum arc discharge, a cold cathode arc source continually emits ion beams of coating elements with high currency density and high ionizing ratio. As the ion bombard and diffusion working on, the surface of the parts form deposited layer, penetrated layer and hybrid layer. Under lab condition, a commercial magnesium alloy Az91 had been coated with Ti film layer with the aim of improving its’ anti-corrosion performance. This paper mainly summarized our studies on the testing and analyzing of the coating layer. The composition and microstructure of the coating layer had been analyzed by means of X-ray diffraction (XRD) and glow discharge spectrum (GDS), and the surface appearance had been surveyed by scanning electronic microscope (SeM). The adhesion strength between film and matrix had been evaluated by experiments of sticking-tearing. The results indicated that the coated layer on magnesium alloy were homogeneous, dense and robustly adhered.

关键词：钛涂层镁合金电弧辉光放电等离子穿透粘附强度

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Post-Mortem MRI and Histopathology in Neurologic Disease:A Translational Approach

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Neuroscience Bulletin 2019年第2期35卷 229-243页

作者： Laura e.Jonkman Boyd Kenkhuis Jeroen J.G.Geurts Wilma D.J.van de Berg Department of Anatomy and Neurosciences Amsterdam Neuroscience Amsterdam UMC Vrije Universiteit Amsterdam Department of Human Genetics Leiden University Medical Center Department of Radiology Leiden University Medical Center

In this review, combined post-mortem brain magnetic resonance imaging(MRI) and histology studies are highlighted, illustrating the relevance of translational approaches to de?ne novel MRI signatures of neuropathological lesions in neuroin?ammatory and neurodegenerative disorders. Initial studies combining post-mortem MRI and histology have validated various MRI sequences,assessing their sensitivity and speci?city as diagnostic biomarkers in neurologic disease. More recent studies have focused on de?ning new radiological(bio)markers and implementing them in the clinical(research) setting. By combining neurological and neuroanatomical expertise with radiological development and pathological validation,a cycle emerges that allows for the discovery of novel MRI biomarkers to be implemented in vivo. examples of this cycle are presented for multiple sclerosis, Alzheimer's disease, Parkinson's disease, and traumatic brain *** applications have been shown to be successful, while others require further validation. In conclusion, there is much to explore with post-mortem MRI and histology studies, which can eventually be of high relevance for clinical practice.

关键词： MRI Histology Biomarkers Multiple sclerosis Alzheimer’s disease Parkinson’s disease

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Transitions in health service use among women with poor mental health:a 7-year follow-up

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Family Medicine and Community Health 2022年第2期10卷 1-10页

作者： Xenia Dolja-Gore Deborah Loxton Catherine D'este Julie e Byles Research Centre of Gender Health and AgeingThe University of NewcastleCallaghanNew South WalesAustralia The Australian Longitudinal Study on Women's Health The University of NewcastleCallaghanNew South WalesAustralia National Centre for epidemiology and Population Health(NCePH) Australian National UniversityCanberraAustralian Capital TerritoryAustralia

Objective Women suffering from mental health problems require varied needs of mental health service *** between general practitioner and mental health services use are available through the Better Access Scheme initiative,for those in need of *** study’s aim was to identify trajectories of mental health service utilisation by Australian *** The Australian Longitudinal Study on Women’s Health data linked to the administrative medical claims dataset were used to identify subgroups of women profiled by their mental health service use from 2006 to *** growth mixture model is a statistical method to profile subgroups of individuals based on their responses to a set of observed variables allowing for changes over *** class groups were identified,and used to examine predisposing factors associated with patterns of mental health service use change over *** This study was conducted in *** National representative sample of women of born in 1973-1978,who were aged between 28 and 33 years at the start of our study *** Six latent class trajectories of women’s mental health service use were identified over the period ***,one-quarter of the sample were classified as the most recent users,while approximate equal proportions were identified as either early users,late/low user or late-high ***,subgroups were defined as the consistent-reduced user and the late-high users,over *** 7.2%of the sample was classified as consistent high users who potentially used the services each *** These findings suggest that use of the Better Access Scheme mental health services through primary care was varied over time and may be tailored to each individual’s needs for the treatment of depressive symptoms.

关键词： service services Transition

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Terahertz aqueous photonics

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Frontiers of Optoelectronics 2021年第1期14卷 37-63页

作者： Qi JIN Yiwen e Xi-Cheng ZHANG The Institute of Optics University of RochesterRochesterNY 14627USA

Developing efficient and robust terahertz(THz)sources is of incessant interest in the THz community for their wide *** successive effort in past decades,numerous groups have achieved THz wave generation from solids,gases,and ***,liquid,especially liquid water has never been demonstrated as a THz *** main reason leading the impediment is that water has strong absorption characteristics in the THz frequency regime.A thin water film under intense laser excitation was introduced as the THz source to mitigate the considerable loss of THz waves from the ***-induced plasma formation associated with a ponderomotive forceinduced dipole model was proposed to explain the generation *** the one-color excitation scheme,the water film generates a higher THz electric field than the air does under the identical experimental *** the case of air,THz wave generation from liquid water prefers a sub-picosecond(200-800 fs)laser pulse rather than a femtosecond pulse(~50 fs).This observation results from the plasma generation process in *** the two-color excitation scheme,the THz electric field is enhanced by one-order of magnitude in comparison with the one-color ***,coherent control of the THz field is achieved by adjusting the relative phase between the fundamental pulse and the second-harmonic *** eliminate the total internal reflection of THz waves at the water-air interface of a water film,a water line produced by a syringe needle was used to emit THz *** expected,more THz radiation can be coupled out and *** wave generation from other liquids were also tested.

关键词： terahertz(THz)wave generation liquid water laser-induced plasma

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Neurochemical metabolites in the medial prefrontal cortex in bipolar disorder A proton magnetic resonance spectroscopy study

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Neural Regeneration Research 2012年第36期7卷 2929-2936页

作者： Osman zdel Demet Kalayci Gülfizar Szeri-Varma Yilmaz Kiroglu Selim Tümkaya Tuge Toker-Ugurlu Department of Psychiatry Faculty of MedicinePamukkale University Department of Psychiatry Antalya Training and Research Hospital Department of Radiology Faculty of MedicinePamukkale University

The aim of this study was to investigate proton magnetic resonance spectroscopy metabolite values in the medial prefrontal cortex of individuals with euthymic bipolar disorder. The subjects consisted of 15 patients with euthymic bipolar disorder type I and 15 healthy controls. We performed proton magnetic resonance spectroscopy of the bilateral medial prefrontal cortex and measured levels of N-acetyl aspartate, choline and creatine. Levels of these three metabolites in the medial prefrontal cortex were found to be lower in patients with bipolar disorder compared with healthy controls. A positive correlation was found between illness duration and choline levels in the right medial prefrontal cortex. Our study suggests that during the euthymic period, there are abnormalities in cellular energy and membrane phospholipid metabolism in the medial prefrontal cortex, and that this may impair neuronal activity and integrity.

关键词： bipolar disorder proton magnetic resonance spectroscopy medial prefrontal cortex N-asetylaspartate choline creatine degradation mood disorder neurochemical metabolite illness duration neural regeneration

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Characteristics of S/L Interface evolution during High Rate Directional Solidification

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Journal of Materials Science & Technology 2001年第3期17卷 299-302页

作者： Hengzhi FU and Xingguo GeNG StateKey Laboratory of Solidification Processing, Northwestern Polytechnical University, Xi’an 710072, China e-mail: fhzh@*** Lab. of Solidification Proc. Northwestern Polytech. Univ. Xi'an 710072 China

The present paper aims to the characterization of high rate direction solidification on AI-Mn and AI-Cu alloys. It is indicated that the relevant cooling rate of high rate directional solidification is defined within 10(0)similar to 10(3) K/s that is located in the region between near-equilibrium slow growth rate and rapid solidification rate beyond equilibrium condition, and at the meantime there occurred a series of turning effect of interface stability and morphologies. With the increase of growth velocity the interface with planar front evolved to cells and dendrites at the stage of near-equilibrium and with further increase of growth rate they transformed reversely from dendrites to cell structure and then to absolute stability of planar interface. An explanation based on effective constitutional supercooling about the evolution of interface morphologies with the change of growth rate was proposed.

关键词： rate

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Manipulation of bicarbonate concentration in sperm capacitation media improves in vitro fertilisation output in porcine species

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Journal of Animal Science and Biotechnology 2019年第2期10卷 375-389页

作者： Cristina Soriano-úbeda Jon Romero-Aguirregomezcorta Carmen Matás Pablo e.Visconti Francisco A.García-Vázquez Department of Physiology Faculty of Veterinary ScienceInternational Excellence Campus for Higher Education and Research“Campus Mare Nostrum”University of Murcia30100 MurciaSpain Institute for Biomedical Research of Murcia(IMIB-Arrixaca) MurciaSpain Department of Physiology Faculty of Medicine and NursingUniversity of the Basque Country UPV/EHULeioaBizkaiaSpain.4Department of Veterinary and Animal SciencesUniversity of MassachusettsAmherstMAUSA.

Background: The in vivo concentration of bicarbonate(HCO3-), one of the essential sperm capacitating effectors,varies greatly in the different environments sperm go through from cauda epididymis to the fertilisation site. On the contrary, porcine in vitro sperm capacitation and fertilisation media usually contains a standard concentration of25 mmol/L, and one of the main problems presented is the unacceptable high incidence of polyspermy. This work hypothesised that by modifying the HCO3-concentration of the medium, the output of in vitro sperm capacitation and fertilisation could be ***: Once exposed to the capacitation medium, the intracellular pH(pHi) of spermatozoa increased immediately even at low concentrations of HCO3-, but only extracellular concentrations of and above 15 mmol/L increased the substrates protein kinase A phosphorylation(pPKAs). Although with a significant delay, 15 mmol/L of HCO3-stimulated sperm linear motility and increased other late events in capacitation such as tyrosine phosphorylation(Tyr-P) to levels similar to those obtained with 25 mmol/L. This information allowed the establishment of a new in vitro fertilisation(IVF)system based on the optimization of HCO3-concentration to 15 mmol/L, which led to a 25.3% increment of the viable zygotes(8.6% in the standard system vs. 33.9%).Conclusions: Optimising HCO3-concentrations allows for establishing an IVF method that significantly reduced porcine polyspermy and increased the production of viable zygotes. A concentration of 15 mmol/L of HCO3-in the medium is sufficient to trigger the in vitro sperm capacitation and increase the fertilisation efficiency in porcine.

关键词： Adcy10 Boar Monospermy PKA

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