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Pressure pain sensitivity: A new stress measure in children and adolescents with type 1 diabetes?

第15届世界禽病大会、中国畜牧兽医学会2007年学术年会

作者： annemarie bouma Ermias Woldemariam Hans Vernooij Arjan Stegeman 宋立 Department of Farm Animal Health Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands Department of Farm Animal Health Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands Department of Farm Animal Health Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands Department of Farm Animal Health Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands

荷兰采用一种粪便和盲肠样品标准培养程序作为肉鸡嗜热空肠弯曲菌的日常监测,本项研究的目的是量化这种非金标准检测方法的特异性和敏感性。数据的分析来自1600份肉鸡样品,一部分样品既有粪

关键词：空肠弯曲菌培养敏感性特异性贝氏统计学

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World Journal of Clinical Pediatrics 2024年第1期13卷 150-154页

作者： annemarie Cecilie Grauslund Emilie Bundgaard Lindkvist Steffen Ullitz Thorsen Søren Ballegaard Jens Faber Jannet Svensson Anna Korsgaard Berg Department of Pediatrics Herlev and Gentofte HospitalHerlev 2730Denmark Copenhagen University Hospital Steno Diabetes Center CopenhagenHerlev 2730Denmark Department of Clinical Immunology RigshospitaletUniversity of CopenhagenCopenhagen 2100Denmark Department of Endocrinology Herlev and Gentofte HospitalHerlev 2730Denmark Department of Clinical Medicine Faculty of Health and Medical SciencesUniversity of CopenhagenCopenhagen 2200Denmark

Type 1 diabetes(T1D)is associated with general-and diabetes-specific stress which has multiple adverse *** measuring stress is of great *** algometer measuring pressure pain sensitivity(PPS)has been shown to correlate to certain stress measures in ***,it has never been investigated in children and *** aim of our study was to examine associations between PPS and glycated hemoglobin(HbA1c),salivary cortisol and two questionnaires as well as to identify whether the algometer can be used as a clinical tool among children and adolescents with ***-three participants aged 6-18 years and diagnosed with T1D were included in this study with data from two study *** cortisol,PPS and questionnaires were collected,measured,and answered on ***1c was collected from medical *** found correlations between PPS and HbA1c(rho=0.35,P=0.046),cortisol(rho=-0.25,P=0.02)and Perceived Stress Scale(rho=-0.44,P=0.02)in different subgroups based on *** scored higher in PPS than females(P<0.001).We found PPS to be correlated to HbA1c but otherwise inconsistent in *** PPS values indicated either measurement difficulties or hypersensibility towards pain.

关键词： Stress Children and adolescents Type 1 diabetes Autonomic dysfunction

Surgical approach affecting long-term urinary continence status after robot-assisted laparoscopic prostatectomy prospectively evaluated using self-reported functional status(Expanded Prostate Cancer Index Composite,EPIC-26)

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New Replacement Name for Rana paradoxa Mocquard,1890 with Designations of Lectotypes for Rana paradoxa and Rana conspicillata Günther,1872:Both Synonymized with Limnonectes kuhlii (Tschudi,1838) (Dicroglossidae:Dicroglossinae)

当代泌尿学（英文） 2024年第1期18卷 61-65页

作者： Mathias Reichert Ame Strauß Joost Wilhelm Voß Hans Christoph von Knobloch Hannah Maria Neuenhofer annemarie Uhlig Lutz Trojan Mirjam Naomi Mohr Department of Urology University Medical CenterGoettingenGermany Department of Pediatrics University HospitalBonnGermany

Purpose:The aim of the study was to examine the influence of the surgical approach for robot-assisted laparoscopic prostatectomy(RALP)on long-term urinary continence status in the era of self-reported functional status measures using the Expanded Prostate Can-cer Index Composite 26.Materials and methods:This is a prospective evaluation of 232 patients undergoing RALP between September,2019 and September,*** continence status and postoperative incontinence(pad usage)were evaluated 12 months after RALP using Expanded Prostate Cancer Index Composite 26 *** were categorized according to their surgical approach and outcome into the following groups:successful nerve sparing(NS),primarily without nerve sparing(***),and no nerve sparing by secondary resection(NNS by SR).The median levels of their questionnaire outcomes were evaluated and compared using the Wilcoxon rank sum test with continuity correction.Results:Urinary continence status 12 months after RALP differed significantly between the NS and ***(p=0.0071)and the NS and NNS by SR(p=0.0076)*** was no significant difference between the *** and NNS by SR(p=0.53)*** usage 12 months after RALP had no significant difference with regard to SR of the neurovascular bundle(p=0.14).Conclusions:Patient-reported outcomes of long-term urinary continence status seem to show no difference in postoperative conti-nence,regardless of whether a non-nerve-sparing result was planned or reached through ***,preservation of neurovascular bundle seems to lead to better long-term continence rates.

关键词： Expanded Prostate Cancer Index Composite 26 Nerve sparing Prostate cancer Robot-assisted radical prostatectomy Surgical approach Urinary incontinence

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Asian Herpetological Research 2013年第3期4卷 187-189页

作者： Masafumi MATSUI Alain DUBOIS annemarie OHLER Graduate School of Human and Environmental Studies Kyoto UniversitySakyoKyoto 606-8501Japan Vertébrés:Reptiles et Amphibiens UMR 7205 OSEBDépartement Systématique et EvolutionMuséum National d'Histoire NaturelleCP 3025 rue Cuvier75005 ParisFrance

Fanged frogs, now called Limnonectes kuhlii, from Borneo are remotely related to true Javanese L. kuhliL For future taxonomy of Bornean fanged frogs, we fix the nomenclatural status of two existing names, Rana conspicillata Giunther, 1872 and Rana paradoxa Mocquard, 1890. Morphological comparison of the type-series revealed heterospecific relationships of the two species. For R. conspicillata, we designate BMNH 1947.***.29.20 as the lectotype, and for R. para doxa, we also designate MNHN 1889.222 as the lectotype and propose a replacement name Limnonectes mocquardi, in order to stabilize their nomenclature.

关键词： fanged frogs Limnonectes kuhlii Borneo nomenclature lectotype replacement name

Specific changes in the expression of imprinted genes in prostate cancer--implications for cancer progression and epigenetic regulation

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Asian Journal of Andrology 2012年第3期14卷 436-450,I0007页

作者： Teodora Ribarska Klaus-Marius Bastian annemarie Koch Wolfgang A Schulz Department of Urology Heinrich Heine University 40225 Duesseldorf Germany 1

Epigenetic dysregulation comprising DNA hypermethylation and hypomethylation, enhancer of zeste homologue 2 （EZH2） overexpression and altered patterns of histone modifications is associated with the progression of prostate cancer. DNA methylation, EZH2 and histone modifications also ensure the parental-specific monoallelic expression of at least 62 imprinted genes. Although it is therefore tempting to speculate that epigenetic dysregulation may extend to imprinted genes, expression changes in cancerous prostates are only well documented for insulin-like growth factor 2 （IGF2）. A literature and database survey on imprinted genes in prostate cancer suggests that the expression of most imprinted genes remains unchanged despite global disturbances in epigenetic mechanisms. Instead, selective genetic and epigenetic changes appear to lead to the inactivation of a sub-network of imprinted genes, which might function in the prostate to limit cell growth induced via the PI3K/Akt pathway, modulate androgen responses and regulate differentiation. Whereas dysregulation of IGF2 may constitute an early change in prostate carcinogenesis, inactivation of this imprinted gene network is rather associated with cancer progression.

关键词： androgen signalling imprinted genes loss of imprinting PI3K signalling prostate cancer

Sap flow for beech(Fagus sylvatica L.)in a natural and a managed forest—effect of spatial heterogeneity

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Journal of Plant Ecology 2011年第1期4卷 23-35页

作者： Lise Dalsgaard Teis Nørgaard Mikkelsen annemarie Bastrup-Birk Forest and Landscape Faculty of Life SciencesUniversity of CopenhagenRolighedsvej 231958 Frederiksberg CDenmark RisøNational Laboratory for Sustainable Energy Technical University of DenmarkFrederiksborgvej 399P.O.Box 494000 RoskildeDenmark

Aims Beech(Fagus sylvatica L.)is an important species in natural and managed forests in *** drought-sensitive species dominates even-aged stands as well more natural stands composed of a mixture of tree species,age and size *** study evaluates the extent that heterogeneity in spacing and tree diameter affect the seasonal availability and use of *** Two stands were evaluated:(i)a heterogeneous forest remnant(NAT)with trees up to;300 years old,a mean top height of 28.4 m and a total of 733 stems ha1with stem diameters averaging 18 cm and(ii)an even-aged 80-year old stand(MAN),with a height of 25 m,and a total of 283 stems ha1 with diameters averaging 38 *** sap flow,Js(g m2 s1),was continuously measured in 12(MAN)and 13(NAT)trees using 20-mm long heat dissipation *** tree measures of sap flow were correlated using non-linear statistical methods with air vapour pressure deficit(D,hPa)and global radiation(Rg,J m2 day1),along with constraints imposed by reductions in soil water content(SWC).SWC was measured as volumetric%using time domain *** Findings The daily integrated Js(Js-sum)for trees growing in the evenly spaced MAN stand and trees in canopy and closed forest positions in NAT stand decreased as the availability of soil moisture was *** the heterogeneous NAT stand,SWC in a recently formed canopy gap remained high throughout the vegetation *** on regression models,the predicted relative decrease in Js-sum for dry relative to moist soil water conditions in the closed forest(at mean daily D=10 hPa)was 7–11%for trees near the gap and 39–42%for trees in the closed *** MAN,the reduction in Js-sum was 29%in dry relative to moist ***-sum in the outer 20 mm of the xylem in NAT was lower than that in MAN and the rate of decline in Js with xylem depth was less in NAT than in *** MAN,Js-sum in deep and outer xylem was negatively affected at low soil moisture availability

关键词： canopy gap canopy structure tree size tree water use

Acute hepatitis induced by an Aloe vera preparation: A case report

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World Journal of Gastroenterology 2005年第2期11卷 303-304页

作者： Christian Rabe annemarie Musch Peter Schirmacher Wolfgang Kruis Robert Hoffmann Department of Medicine Evangelisches Krankenhaus Koeln KalkCologneGermany Institute of Pathology University of CologneCologneGermany

AIM: Aloe vera, plant extracts of Aloe barbadensis miller,is widely used in phytomedicine. The first case of acute hepatitis due to this compound was ***: Description of a clinical ***: Hepatitis in a 57-year old female could be linked to the ingestion of Aloe barbadensis miller compounds. The patient's hepatitis resolved completely after discontinuing this ***: The case emphasizes the importance of considering phytopharmaceutical over-the-counter drugs as causative agents of hepatitis.

关键词： Hepatitis Aloe vera Acute diseases

High demand for firewood leads to overuse of walnut-fruit forests in Kyrgyzstan

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Journal of Forestry Research 2013年第4期24卷 797-800页

作者： Maik Rehnus annemarie Nazarek Davlet Mamadzhanov Bronislav Ivanovitch Venglovsky Jean-Pierre Sorg Groupe de foresterie pour le développement Department of Environmental SciencesETH Zurich Forest Research Institute Laboratory of forest resources Fund "Forest protection"

After Kyrgyzstan gained independence in 1991, the importance of the primary sector for food- and energy-supply increased significantly. This has led to a discussion about the sustainability of current firewood use. We investigated firewood collection and use practices in three selected villages and analysed differences between the annual increment of woody biomass and firewood consumption for heating during winter months. The calculated individual firewood consumption is on average 3.90 kg/capita/heating day and the calculation of differences between increment and consumption shows that in minimum one village the surrounding forests are overused for firewood collection. Pressure on the forest and the overuse of preferred tree species for firewood can lead to an overuse of the resource and to a decrease in the genetic diversity of these species in the walnut-fruit forests which are considered as a biodiversity hotspot of international significance due to the diversity of woody.

关键词： swalnut Juglans regia firewood consumption overexploitation

Tapping the tree-ring archive for studying effects of resin extraction on the growth and climate sensitivity of Scots pine

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Forest Ecosystems 2017年第3期4卷 167-173页

作者： Ernst van der Maaten annemarie Mehl Martin Wilmking Marieke van der Maaten-Theunissen Institute of Botany and Landscape Ecology University of Greifswald

Background： In the German Democratic Republic（GDR）, resin tapping in Scots pine（Pinus sylvestris L.） forests was a major economic activity, and resin-tapped stands are frequently found up until this day. In this study, we investigate how the mechanical damage caused by resin tapping affects the growth and climate sensitivity of Scots pine using a dendroecological ***： Tree-ring samples were collected from resin-tapped and non-tapped trees in two forest areas in northeastern Germany, and tree-growth patterns were analyzed. For elucidating effects of resin tapping on the climate sensitivity of pine growth, climate-growth relationships and pointer years were ***： We observed that resin tapping positively affects tree growth at breast height, likely as wood formation is concentrated on the living part of the bole（i.e. after tapping there is no growth taking place on the tapping face due to the mechanical damage done to the cambium）. We observed no differences in the climate sensitivity of tapped and non-tapped trees, nor in the occurrence of extreme growth ***： Our results highlight that resin extraction is, apart from inflicting mechanical damage, not altering the sensitivity of Scots pine growth to climatic conditions.

关键词： Climate-growth relationships Dendroecology Mechanical damage