检索结果-南通市图书馆

Optic nerve injury-induced regeneration in the adult zebrafish is accompanied by spatiotemporal changes in mitochondrial dynamics

引用

Neural Regeneration Research 2023年第1期18卷 219-225页

作者： An Beckers Luca Masin annelies van dyck Steven Bergmans Sophie vanhunsel Anyi Zhang Tine Verreet Fabienne EPoulain Karl Farrow Lieve Moons Neural Circuit Development and Regeneration Research Group Animal Physiology and Neurobiology SectionDepartment of BiologyKatholieke Universiteit LeuvenLeuvenBelgium Poulain Lab Department of Biological SciencesUniversity of South CarolinaColumbiaSCUSA Neuro-Electronics Research Flanders Vlaams Instituut voor Biotechnologie(VIB)LeuvenBelgium Leuven Brain Institute LeuvenBelgium Imec LeuvenBelgium

Axonal regeneration in the central nervous system is an energy-intensive *** contrast to mammals,adult zebrafish can functionally recover from neuronal *** raises the question of how zebrafish can cope with this high energy *** previously showed that in adult zebrafish,subjected to an optic nerve crush,an antagonistic axon-dendrite interplay exists wherein the retraction of retinal ganglion cell dendrites is a prerequisite for effective axonal *** postulate a‘dendrites for regeneration’paradigm that might be linked to intraneuronal mitochondrial reshuffling,as ganglion cells likely have insufficient resources to maintain dendrites and restore axons ***,we characterized both mitochondrial distribution and mitochondrial dynamics within the different ganglion cell compartments(dendrites,somas,and axons)during the regenerative *** nerve crush resulted in a reduction of mitochondria in the dendrites during dendritic retraction,whereafter enlarged mitochondria appeared in the optic nerve/tract during axonal *** dendritic regrowth in the retina,mitochondrial density inside the retinal dendrites returned to baseline ***,a transient increase in mitochondrial fission and biogenesis was observed in retinal ganglion cell somas after optic nerve *** together,these findings suggest that during optic nerve injury-induced regeneration,mitochondria shift from the dendrites to the axons and back again and that temporary changes in mitochondrial dynamics support axonal and dendritic regrowth after optic nerve crush.

关键词： axonal regeneration central nervous system dendrite remodeling energy metabolism fission mitochondria mitochondrial trafficking optic nerve crush retina zebrafish

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Artificial intelligence meets body sense: task-driven neural networks reveal computational principles of the proprioceptive pathway

引用

Signal Transduction and Targeted Therapy 2024年第8期9卷 3147-3149页

作者： Leonard E.van dyck Frank Bremmer Katharina Dobs Department of Psychology Justus Liebig University GiessenGiessenGermany Max Planck Institute for Human Cognitive and Brain Sciences LeipzigGermany Center for Mind Brain and BehaviorUniversities of MarburgGiessenand DarmstadtMarburgGermany Department of Neurophysics Philipps-Universitat MarburgMarburgGermany

In a recent study published in Cell,Marin Vargas and Bisi et al.1 present an innovative approach to unravel the computational principles underlying proprioceptive processing in non-human *** findings showcase the utility of task-driven modeling in advancing neuroscience and offer translational potential by providing seminal insights into the goals and mechanisms by which the brain encodes body position and movements.

关键词： networks neural principles

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The future of high resolution electron microscopy

引用

电子显微学报 2000年第5期19卷 667-678页

作者： D van dyck Department of Physics,University of Antwerp (RUCA),Groenenborgerlaan 171,B-2020 Antwerpen,Belgium University of Antwerp 比利时 Antwerpen B- 2 0 2 0

The state of the art and the future in quantitative high resolution electron microscopy are discussed in the framework of parameter estimation. Reconstruction methods are then to be considered as direct methods to yield a starting structure for further refinement. With the increasing flexibility of the instruments, computer aided experimental strategy will become important.

关键词：高分辨率电子显微镜发展前景

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

FUTURE PROSPECTS FOR DIRECT STRUCTURE RETRIEVAL IN HIGH RESOLUTION ELECTRON MICROSCOPY

FUTURE PROSPECTS FOR DIRECT STRUCTURE RETRIEVAL IN HIGH RESO...

引用

Sixteenth Congress of the International Union of Crystallography

作者： D.van dyck University of Antwerp（RUCA） Belgium

＜正＞We are living in a very exciting period for structural research using high resolution electron microscopy（HREM）.Indeed,the possibility to "see" the individual atoms of which matter is constructed seems within *** technological improvements allow to obtain a resolution of" about O.I ***,the potential power of the technique is still severely limited by the problem of quantitative interpretation of the *** far the only method to extract

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Selecting a Strategic Logistics Service Provider for Subsea Engineering Companies on the Tweneboa, Enyenra and Ntomme （TEN） Project in Ghana

引用

Journal of Shipping and Ocean Engineering 2016年第2期6卷 95-104页

作者： Emmanuel Sena Gohoho Jonas Aryee George Kobina van dyck Department of Ports and Shipping Regional Maritime University P. 0 Box GP 1115 Accra Ghana School of Economics and Management Shanghai Maritime University Shanghai 201306 China

The research dealt with assessment of logistics service providers＇ capabilities in SECs （supporting subsea engineering companies） on the Tweneboa, Enyenra and Ntomme （TEN） project in Ghana. SECs need logistics service providers who offer consolidated services for project optimization and fulfillment of local content requirements of the project. Relevant Staffof7 SECs and 10 logistics service providers in Ghana formed part of the target group. The weighted scoring model was used in selecting a logistics service provider based on certain criteria. The selection criteria included Quality, Health, Safety and Environmental （QHSE） policies [Q], Compliance to regulations （GRA, Work permit, petroleum regulation） [C], Delivery of goods on time and response rate to deliver [D], Vessel, Cargo attendance and transportation （sea freight and air freight） [V], and Logistics （Personal logistics and Logistics base facilities） [L]. The study concluded Consolidated Shipping Agency （Conship） was the best Logistics Service Provider to offer the best consolidated services for project optimization under the TEN project.

关键词： Logistics service providers analytical hierarchy process subsea engineering weighted scoring model.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

软下疳、性病性淋巴肉芽肿和腹股沟肉芽肿的实验室检查技术

引用

国外医学（皮肤性病学分册） 1993年第3期19卷 153-154页

作者： van dyck E 王千秋

概述了三种以生殖器溃疡为主要表现的性传播疾病——软下疳、性病性淋巴肉芽肿和腹股沟肉芽肿的实验室检查技术.

关键词：下疳淋巴肉芽肿腹股沟肉芽肿

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An Empirical Assessment of Marine Debris, Seawater Quality and Littering in Ghana

引用

Journal of Geoscience and Environment Protection 2016年第5期4卷 21-36页

作者： Irene P. van dyck Francis K. E. Nunoo Elaine T. Lawson Institute for Environment and Sanitation Studies University of Ghana Accra Ghana Department of Marine & Fisheries Sciences University of Ghana Accra Ghana

A baseline survey was carried out at four beaches along Ghana’s Accra-Tema coastline over a period of sixteen weeks to determine beach quality, seawater quality and the perception of beach users towards littering. A total of 18,241 items of marine debris which weighed 297.59 kg were collected. Plastic materials were the dominant debris, accounting for 63.72% of total debris. Land-based marine debris formed the largest proportion of debris collected (93% of items/m2 and 85 kg/m2). Water quality analysis revealed high mean levels of coliforms and E. coli above World Health Organization (WHO) levels on all four beach locations. A social survey that targeted beach users and some stakeholders revealed a habit of littering and beach users as the main source of litter generation on Ghana’s beaches. Intensive education, continuous monitoring and the enforcement of appropriate policy initiatives remain vital to addressing beach and water quality issues along Ghana’s coastline.

关键词： Marine Debris Accra-Tema Coastline Ghana Plastics Seawater Quality Littering Perception

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Manifold learning of four-dimensional scanning transmission electron microscopy

引用

npj Computational Materials 2019年第1期5卷 1097-1104页

作者： Xin Li Ondrej E.dyck Mark P.Oxley Andrew R.Lupini Leland McInnes John Healy Stephen Jesse Sergei V.Kalinin Center for Nanophase Materials Sciences Oak Ridge National LaboratoryOak RidgeTN 37831USA Institute for Functional Imaging of Materials Oak Ridge National LaboratoryOak RidgeTN 37831USA Tutte Institute for Mathematics and Computing OttawaCanada

Four-dimensional scanning transmission electron microscopy(4D-STEM)of local atomic diffraction patterns is emerging as a powerful technique for probing intricate details of atomic structure and atomic electric ***,efficient processing and interpretation of large volumes of data remain challenging,especially for two-dimensional or light materials because the diffraction signal recorded on the pixelated arrays is *** we employ data-driven manifold leaning approaches for straightforward visualization and exploration analysis of 4D-STEM datasets,distilling real-space neighboring effects on atomically resolved deflection patterns from single-layer graphene,with single dopant atoms,as recorded on a pixelated *** extracted patterns relate to both individual atom sites and sublattice structures,effectively discriminating single dopant anomalies via multimode *** believe manifold learning analysis will accelerate physics discoveries coupled between data-rich imaging mechanisms and materials such as ferroelectric,topological spin,and van der Waals heterostructures.

关键词： manifold straight details

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

有特殊保健需求儿童的数量和特征

引用

世界核心医学期刊文摘（儿科学分册） 2005年第2期1卷 32-33页

作者： van dyck P.C. Kogan M.D. McPherson M.G. 刘莉 Dr.Maternal and Child Health BureauHlth.Rsrc.and Serv.Administration 5600 Fishers LaneRockvilleMD20857United States

背景:从保健服务、经济和政策前景角度看,有特殊保健需求(SHCNs)的儿童是一个很重要的群体。然而,迄今为止还没有全国范围内关于这类人群数量的资料,也没有能被普遍接受的健康护理方面的标准。目的:提供全国SHCNs儿童的数量及其特征。

关键词：保健需求健康护理保健服务人群数量学龄期电话调查社会经济学意度保健模式乔治亚州

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

雌激素替代疗法治疗轻到中度Alzheimer病：随机对照试验

引用

美国医学会杂志（中文版） 2000年第6期19卷 282-290页

作者： Ruth A. Mulnard, RN, DNSc Anthony Gamst, PhD Michael Grundman, MD,MPH Ronald Thomas, PhD Leon J. Thal, MD Alzheimer病协作组 Carl W. Cotman, PhD Claudia Kawas, MD Christopher H. van dyck, MD Mary Sano, PhD Rachelle Doody, MD, PhD Elizabeth Koss, PhD Eric Pfeiffer, MD Shelia Jin, MD, MPH

背景：几项小型临床试验提示雌激素替代疗法可能有助于女性Alzheimer病（AD）患者的治疗。　　目的：确定雌激素替代疗法能否改善轻到中度女性AD患者总体功能、认知或日常生活能力。　　设计：Alzheimer病协作组于1995年10月至1999年1... 详细信息

背景：几项小型临床试验提示雌激素替代疗法可能有助于女性Alzheimer病（AD）患者的治疗。　　目的：确定雌激素替代疗法能否改善轻到中度女性AD患者总体功能、认知或日常生活能力。　　设计：Alzheimer病协作组于1995年10月至1999年1月进行的一项随机、双盲、安慰剂对照临床试验。　　参加单位：美国32个研究中心。　　受试对象：总共120例轻到中度女性AD患者。细微精神状态检查评分介于12～28分间，既往已行子宫切除术。　　干预：受试者随机服用雌激素0.625 mg/d（n=42）、1.25 mg/d（n=39）或者剂型相同的安慰剂（n=39）。1例患者于随机后接受药物治疗前退出试验；97例完成试验。　　主要结果评定：主要结果评定指标为临床整体印象的改变（CGIC），分值为7分，采用意向治疗(intent-to-treat)分析。次要指标包括其他总评估以及情绪、特殊认知功能（记忆、注意力和语言）、运动功能和日常生活能力；于随访 2、6、12和15个月时，对雌激素组与安慰剂组进行比较。　　结果：雌激素组与安慰剂组CGIC评分为5.1比5.0 (P=0.43)；雌激素组80%的患者恶化，而安慰剂组74%恶化(P=0.48)。除临床痴呆评分提示雌激素组恶化外(雌激素组与安慰剂组相比治疗后平均变化为0.5比0.2，P=0.01)，两组次要结果指标无显著差异。　　结论：雌激素替代治疗1年不能延缓轻、中度女性AD患者病情的进展，整体功能、认知和功能预后亦无改善。研究结果不支持雌激素对这种疾病有治疗作用的结论。雌激素对AD的潜在预防作用尚需进一步研究。

关键词：早老性痴呆雌激素替代疗法

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：