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Impact of pre-existing cardiometabolic diseases on metastatic cancer stage at diagnosis:a prospective multinational cohort study

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Cancer Communications 2024年第5期44卷 593-597页

作者： Anna Jansana Aviane Auguste Marina Kvaskoff Agnès Fournier Emma Fontvieille Laia Peruchet-Noray Carine Biessy Reynalda Cordova Kristina Elin Nielsen Petersen anne Tjoneland Verena Katzke Rudolf Kaaks Fulvio Ricceri Salvatore Panico Paolo Contiero Maria-Jose Sánchez Jesus Castilla Marta Crous-Bou Alicia Heath Elom Kouassivi Aglago Elisabete Weiderpass Marc James Gunter Pietro Ferrari Elio Riboli Vivian Viallon Heinz Freisling International Agency for Research on Cancer(IARC-WHO) LyonFrance Paris-Saclay University University of Versailles-Saint-Quentin-en-YvelineUniversity Paris-SudFrench National Institute for Health and Medical Research(Inserm)Gustave Roussy“Exposome and Heredity”TeamCESPVillejuifFrance Department of Nutritional Sciences University of ViennaViennaAustria Danish Cancer Society Research Center CopenhagenDenmark Department of Public Health University of CopenhagenCopenhagenDenmark Division of Cancer Epidemiology German Cancer Research CentreHeidelbergGermany Department of Clinical and Biological Sciences University of TurinTurinItaly Unit of Epidemiology Regional Health Service ASL TO3GrugliascoTurinItaly Department of Clinical Medicine and Surgery Federico II UniversityNaplesItaly Environmental Epidemiology Unit Istituto di Ricovero e Cura a Carattere Scientifico(IRCCS)-Istituto Nazionale dei TumoriMilanItaly Cancer Registry of Granada Institute for Biosanitary Research of Granada(ibs.GRANADA)GranadaSpain Epidemiology and Control of Chronic Diseases Group Epidemiology and Public Health Networking Biomedical Research CentreMadridSpain Navarra Public Health Institute PamplonaSpain Unit of Nutrition and Cancer Cancer Epidemiology Research ProgramCatalan Institute of Oncology(ICO)-Bellvitge Biomedical Research Institute(IDIBELL)L’Hospitalet de LlobregatBarcelonaSpain Department of Epidemiology Harvard Tseng-Hsi Chan School of Public HealthBostonMassachusettsUSA Department of Epidemiology and Biostatistics School of Public HealthImperial College LondonSt Mary’s CampusNorfolk PlaceLondonUK

Owing to shared risk factors between cardiometabolic diseases(CMDs)and cancer,coupled with population aging,the lifetime risk of an individual developing cancer after a CMD is ***,biological mechanisms such as insulin resistance or inflammation may not only predispose individuals withCMDto an elevated risk of certain types of cancer but also to a diagnosis of cancer at an advanced stage[1,2].

关键词： diagnosis diseases cancer

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Cellulose Synthases and Synthesis in Arabidopsis

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Molecular Plant 2011年第2期4卷 199-211页

作者： anne Endler Staffan Persson Max-Planck-Institute for Molecular Plant Physiology Am M6hlenberg 1 14476 Potsdam Germany

Plant cell walls are complex structures composed of high-molecular-weight polysaccharides, proteins, and lignins. Among the wall polysaccharides, cellulose, a hydrogen-bonded β-1,4-1inked glucan microfibril, is the main load-bearing wall component and a key precursor for industrial applications. Cellulose is synthesized by large multi-meric cellulose synthase （CesA） complexes, tracking along cortical microtubules at the plasma membrane. The only known components of these complexes are the cellulose synthase proteins. Recent studies have identified tentative interaction partners for the CesAs and shown that the migratory patterns of the CesA complexes depend on phosphorylation status. These advances may become good platforms for expanding our knowledge about cellulose synthesis in the near future. In addition, our current understanding of cellulose chain polymerization in the context of the CesA complex is discussed.

关键词： Cell expansion cell walls cytoskeleton-cell wall interactions Arabidopsis.

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Angular Dependence of the Second Harmonic Generation Induced by Femtosecond Laser Irradiation in Silica-Based Glasses:Variation with Writing Speed and Pulse Energy

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World Journal of Nano Science and Engineering 2015年第3期5卷 96-106页

作者： Jing Cao Bertrand Poumellec Fran?ois Brisset anne-laure Helbert Matthieu Lancry Institut de Chimie Moléculaire et des Matériaux d’Orsay(ICMMO) CNRS-UniversitéParis SudUniversitéParis SaclayBat.420Campus Orsay91405 OrsayFrance

To control second harmonic generation (SHG) in silica-based glasses is crucial for fabricating photonic devices, such as frequency doubling waveguides. Here, we investigated SHG of laser induced nonlinear optical crystals in silica-based glasses, according to writing speed and pulse energy. We observed two regions with different probing laser polarization angular dependence: a) a well-defined cosine-like curve with period of 180° at low pulse energy (0.8 μJ) whatever the writing speed or at high pulse energy (1.4 μJ) with high writing speed (25 μm/s). This is accounted for by a well-defined texture for the nano crystals with their polar axis oriented perpendicular to the writing laser polarization;and b) a double cosine-like curve revealing a second texture of the crystals at high pulse energy (1.4 μJ) with low writing speed (5 μm/s) and with the polar axis oriented closer parallel to the writing laser polarization. Therefore, a SHG dependence on probing laser polarization angle may show high contrast by a correct choice of the writing speed and pulse energy. These results pave the way for elaboration of nonlinear optical devices.

关键词： Nonlinear Optical Crystal Glass Ceramics Direct Writing Ultrafast Processes Waveguide

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Lithium mapping in a Mg-9Li-4Al-1Zn alloy using electron energy-loss spectroscopy

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Journal of Magnesium and Alloys 2023年第4期11卷 1170-1179页

作者： Yu Zhang laure Bourgeois Yu Chen Zhuoran Zeng Nick Birbilis Philip N.H.Nakashima Department of Materials Science and Engineering Monash UniversityVIC 3800Australia Monash Centre for Electron Microscopy Monash UniversityVIC 3800Australia College of Engineering and Computer Science Australian National UniversityACT 2601Australia Faculty of Science Engineering and Built EnvironmentDeakin UniversityVIC 3125Australia

Magnesium-lithium alloys with high lithium content have been attracting significant attention because of their low density,high formability and corrosion *** properties are dependent on the distribution of lithium,which is difficult to map in the presence of *** this work,a ratio spectrum-imaging method with electron energy-loss spectroscopy(EELS)is demonstrated,which enables the mapping of *** application to LAZ941(Mg-9Li-4Al-1Zn in wt.%),this technique revealed that a key precipitate in the microstructure,previously thought by some to be Mg_(17)Al_(12),is in fact rich in *** result was corroborated with a structural investigation by high-angle annular dark-field scanning transmission electron microscopy(HAADF-STEM),showing this phase to be Al_(1-x)Zn_(x)Li,with x<<*** work indicates the potential offered by this technique for mapping lithium in materials.

关键词： Lithium mapping Magnesium alloys Electron energy-loss spectroscopy(EELS) High-angle annular dark-field scanning transmission electron microscopy(HAADF-STEM)

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Erratum to:Microstructure and texture evolution of nonoriented silicon steel during the punching process

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International Journal of Minerals,Metallurgy and Materials 2023年第6期30卷 1225-1225页

作者： Xiang Fang Wei Wang François Brisset anne-laure Helbert Thierry Baudin School of Automotive Engineering Wuhan University of TechnologyWuhan 430070China Hubei Key Laboratory of Advanced Technology for Automotive Components Wuhan University of TechnologyWuhan 430070China Hubei Collaborative Innovation Center for Automotive Components Technology Wuhan University of TechnologyWuhan 430070China Hubei Research Center for New Energy&Intelligent Connected Vehicle Wuhan University of TechnologyWuhan 430070China Institut de Chimie Moléculaire et des Matériaux d’Orsay UniversitéParis-SaclayCNRS91405 OrsayFrance

The original online version of this article unfortunately contained a *** author’s name in the original online version is incorrect,which is:Xiang Fang,Wei Wang,François Brisset,anne-laure Helberg,and Thierry Baudin ... 详细信息

关键词： Microstructure steel evolution

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Extended Evolutionary Fast Learn-to-Walk Approach for Four-Legged Robots

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Journal of Bionic Engineering 2007年第4期4卷 255-263页

作者： Muh. Anshar Mary-anne Williams Innovation and Technology Research Laboratory Faculty of Information Technology University of Technology Sydney City Campus 15 Broadway Ultimo NSW 2007 Australia

Robot locomotion is an active research area. In this paper we focus on the locomotion of quadruped robots. An effective walking gait of quadruped robots is mainly concerned with two key aspects, namely speed and stability. The large search space of potential parameter settings for leg joints means that hand tuning is not feasible in general. As a result walking parameters are typically determined using machine learning techniques. A major shortcoming of using machine learning techniques is the significant wear and tear of robots since many parameter combinations need to be evaluated before an optimal solution is found. This paper proposes a direct walking gait learning approach, which is specifically designed to reduce wear and tear of robot motors, joints and other hardware. In essence we provide an effective learning mechanism that leads to a solution in a faster convergence time than previous algorithms. The results demonstrate that the new learning algorithm obtains a faster convergence to the best solutions in a short run. This approach is significant in obtaining faster walking gaits which will be useful for a wide range of applications where speed and stability are important. Future work will extend our methods so that the faster convergence algorithm can be applied to a two legged humanoid and lead to less wear and tear whilst still developing a fast and stable gait.

关键词： legged-robots locomotion learning genetic convergence walking gaits

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Science Fiction as a Manifestation of Culture in America

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外国文学研究 2005年第6期27卷 41-47页

作者： Elizabeth anne Hull William Rainey Harper College USA

Culture is broadly viewed as all the human activities that define us as a species. ″Sturgeon’s Law″ (that 90% of everything is inferior) is introduced to defend the study of fiction, and science fiction in particular, in higher education as a way of understanding ourselves better, and perhaps improving the world through the increased understanding of tomorrow’s leaders. Several ways of reading particular works of science fiction are examined, like providing historical contexts for readers, close reading and structural analysis, and application of theories based on particular ideologies or from other disciplines in the social and political sciences (such as feminist theory, Marxist theory, psychological theory, etc.). A conclusion is drawn that for literary analysis, a hybrid methodology, one devised individually for each text, works best.

关键词：科学小说美国文学研究文化背景

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Matrix Roots and Embedding Conditions for Three-State Discrete-Time Markov Chains with Complex Eigenvalues

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Communications in Mathematics and Statistics 2022年第3期10卷 435-450页

作者： Marie-anne Guerry Department of Business Technology and Operations Vrije Universiteit Brussel(VUB)Pleinlaan 21050 BrusselsBelgium

The present paper examines matrix root properties and embedding conditions for discrete-time Markov chains with three states and a transition matrix having complex *** as well as sufficient conditions for the existence of an m-th stochastic root of the transition matrix are *** roots are expressed in analytical form based on the spectral decomposition of the transition matrix,and properties of these matrix roots are proved.

关键词： Markov chain Embedding problem Matrix root Complex eigenvalues

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Application of the Point-Descriptor-Precedence representation for micro-scale traffic analysis at a non-signalized T-junction

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Geo-Spatial Information Science 2023年第3期26卷 406-430页

作者： Amna Qayyum Bernard De Baets laure De Cock Frank Witlox Guy De Tré Nico Van de Weghe Department of Geography Ghent UniversityGhentBelgium Department of Data Analysis and Mathematical Modelling Ghent UniversityGhentBelgium Department of Telecommunications and Information Processing Ghent UniversityGhentBelgium

An intersection of two or more roads poses a risk for potential conflicts among *** the reasons triggering such conflicts are not clear,as they might be too subtle for the human *** environment also plays a part in understanding where,when,and why a particular vehicle interaction has occurred in a certain ***,it is of paramount importance to dive deeper into the vehicle interaction at a micro-scale within the embedded geographical environment,particularly at the *** would in turn assist in evaluating the association of vehicle interactions with conflict risks and near-miss ***,detection of such micro traffic interactions could also be used to improvise the complexity of the already established transport ***,traffic at intersections has been explored mainly for flow estimation,capacity and width measurements,and traffic congestion,etc.,whereas the detection of micro-scale traffic interactions at intersections remains relatively *** this paper,we present a novel approach to retrieve and represent micro-scale traffic movement interactions at a non-signalized T-junction by extending a recently introduced qualitative spatiotemporal Point-Descriptor-Precedence(PDP)*** study how the PDP representation offers a fine solution to study the interaction of traffic flows at *** permits tracking the micro-movement of vehicles in much finer detail,which is used later to retrieve movement patterns from a motion *** conventional approaches,we start our approach with the actual movements before modeling the static intersection ***,with the aid of illustrative examples,we discuss how the length,width,and speed of the vehicles can be exploited in our approach to detect specific patterns more ***,we address the potential benefits of our approach for traffic safety assessment and how it can be extended to a network of

关键词： Vehicle interaction traffic research pattern identification traffic safety spatiotemporal representation movement pattern

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Texture of Rotary-Friction-Welded from Dissimilar Medium Carbon Steels

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World Journal of Condensed Matter Physics 2020年第4期10卷 178-190页

作者： Zakaria Boumerzoug Elena Priymak Anna Stepanchukova anne-laure Helbert François Brisset Thierry Baudin Department of Mechanical Engineering LMSM University of Biskra Biskra Algeria Orenburg State University Orenburg Russia ZBO Drill Industries Orenburg Russia Université Paris-Saclay CNRS Institut de chimie moléculaire et des matériaux d’Orsay Orsay France

The purpose of the present study was to investigate the texture in dissimilar medium carbon steels welded by rotary friction technique. The Electron Backscatter Diffraction (EBSD) technique was the main technique used to investigate the effect of welding on grain size and grain crystallographic orientation in the welded joint. Moreover, the effect of isothermal heat treatment at 600°C on welded joint has been studied knowing that this annealing allows to decrease the residual stresses. EBSD results revealed different subzones in welded joint. The texture in the weld is essentially composed of three components: Goss {110} , Rotated Cube {100} , and Rotated Goss {110} orientation. The heat treatments applied on welded material had a slight effect on texture and grain size.

关键词： Texture Rotary Friction Welding Medium Carbon Steels

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