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Phosphorus mobility in dam reservoir affected by redox oscillations:An experimental study

Journal of Environmental Sciences 2019年第3期31卷 250-263页

作者： anne Rapin Malgorzata Grybos Marion Rabiet brice Mourier Véronique Deluchat Université de Limoges PEIRENE EA 7500 Faculté des Sciences et Techniques Université de Lyon UMR5023 Laboratoire d'Ecologie des Hydrosystèmes Naturels et Anthropisés Université Lyon 1ENTPE CNRS

The internal sedimentary phosphorus(P) load of aquatic systems is able to support eutrophication, especially in dam–reservoir systems where sedimentary P stock is high and where temporary anaerobic conditions occur. The aim of this study therefore is to examine the response of sedimentary P exposed to redox oscillations. Surface sediments collected in the Champsanglard dam–reservoir(on the Creuse River, France) were subjected to two aerobic phases(10 and 12 days) alternated with two anaerobic periods(21 and 27 days)through batch incubations. The studied sediment contained 77 ± 3 μmol/g DW of P, mainly associated with the ascorbate fraction(amorphous Fe/Mn oxyhydroxides). The used sediment was rich in organic matter(OM)(21% ± 1%) with primarily allochthone *** results showed that redox oscillations enhance dissolved inorganic phosphorus release at sediment/water interface. During the first anaerobic stage, the P release was mainly controlled by the dissolution/precipitation of iron minerals. The more pronounced increase of P release during the second anaerobic stage(44%) was due to various mechanisms related to the change in quality of dissolved organic matter(DOM), namely a higher SUVA254 and humification indices. The release of more refractory DOM(rDOM) served to lower the microbial metabolism activity, possibly favored iron oxyhydroxide aggregation and thus limiting iron reduction. In addition, rDOM is able to compete for mineral P sorption sites,leading to a greater P release. In reservoir with predominant allochthone OM input, the release of more aromatic DOM therefore plays an important role in P mobility.

关键词： Phosphorus Sediment Redox Iron Organic matter

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将医疗保健干预措施从试验转化为实践

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英国医学杂志中文版 2010年第6期13卷 361-365页

作者： Paul Glasziou Iain Chalmers Douglas G Altman Hilda Bastian IsabeUe Boutron anne brice Gro Jamtvedt Andrew Farmer Davina Ghersi Trish Groves Carl Heneghan Sophie Hill Simon Lewin Susan Michie Rafael Perera Valerie Pomeroy Julie Tilson Sasha Shepperd John W Williams 周久顺(译) 张孔来(校) Department of Public Health and Primary Care University of Oxford Oxford OX3 7LF James Lind Initiative Oxford OX2 7LG Centre for Statistics in Medicine Oxford OX2 6UD German Institute for Quality and Efficiency in Health Care Cologne Germany INSERM Universite Paris Paris France Norwegian Knowledge Centre for the Health Services Oslo Norway Department of Research Policy and Cooperation World Health Organization Geneva BMJ London Centre for Health Communication and Participation Australian Institute for Primary Care La Trobe University Victoria Australia Division of Psychology and Language Sciences University Coflege London London WC1E 7HB Health and Social Sciences Research Institute Faculty of Health University of East Anglia Norwich Division of Biokinesiology and Physical Therapy University of Southern California Los Angeles CA USA Duke Evidence -based Practice Center Duke University and Durham VA Medical Center Durham NC USA 中国医学科学院基础医学研究所流行病与卫生统计学教研室

成千上万的试验结果从未被用于实践，因为其发表的报告未能详细地描述具体的干预措施。如何才能改进这些报告呢？

关键词：干预措施医疗保健试验转化

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Heterogeneity of mature oligodendrocytes in the central nervous system

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Neural Regeneration Research 2025年第5期20卷 1336-1349页

作者： Chao Weng Adam M.R.Groh Moein Yaqubi Qiao-Ling Cui Jo anne Stratton G.R.Wayne Moore Jack P.Antel Neuroimmunology Unit Montreal Neurological Institute-HospitalDepartment of Neurology and NeurosurgeryMcGill UniversityMontrealQCCanada Department of Neurology Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous *** evidence has challenged the classical view of the functionally static mature oligodendrocyte and revealed a gamut of dynamic functions such as the ability to modulate neuronal circuitry and provide metabolic support to *** the recognition of potential heterogeneity in mature oligodendrocyte function,a comprehensive summary of mature oligodendrocyte diversity is *** delve into early 20th-century studies by Robertson and Río-Hortega that laid the foundation for the modern identification of regional and morphological heterogeneity in mature ***,recent morphologic and functional studies call into question the long-assumed homogeneity of mature oligodendrocyte function through the identification of distinct subtypes with varying myelination ***,modern molecular investigations,employing techniques such as single cell/nucleus RNA sequencing,consistently unveil at least six mature oligodendrocyte subpopulations in the human central nervous system that are highly transcriptomically diverse and vary with central nervous system *** and disease related mature oligodendrocyte variation denotes the impact of pathological conditions such as multiple sclerosis,Alzheimer's disease,and psychiatric ***,caution is warranted when subclassifying mature oligodendrocytes because of the simplification needed to make conclusions about cell identity from temporally confined *** studies leveraging advanced techniques like spatial transcriptomics and single-cell proteomics promise a more nuanced understanding of mature oligodendrocyte *** research avenues that precisely evaluate mature oligodendrocyte heterogeneity with care to understand the mitigating influence of species,sex,central nervous system region,age,and disease,

关键词： aging central nervous system diseases electron microscopy heterogeneity immunohistochemistry myelin sheath natural history neuroglia oligodendroglia single-cell gene expression analysis

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Poverty and Agroforestry Adoption： The Cases of Mucuna pruriens and Acacia auriculiformis in Godohou Village （Southern Benin）

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Journal of Life Sciences 2012年第7期6卷 794-800页

作者： Emile N. Houngbo anne Floquet brice Sinsin National Higher School of Agriculture (ENSTA-Ketou) University of Abomey-Calavi 05 BP 774 Cotonou Benin Faculty of Agriculture University of Abomey-Calavi 05 BP 774 Cotonou Benin

The decomposition of the environmental degradation cost in Benin Republic revealed that the agricultural activities are responsible of the greatest amount of this cost （76.1%）. This situation is strengthened by the fallow periods shortening （and even suppression） in the southern Benin in general, because of demographic pressure. The promotion of some improved fallow technologies （IFT） was then launched some decades ago. This study focused on two IFT of high agro-ecological value, Mucuna pruriens and Acacia auriculiformis, in order to determine the influence of the farmers＇ wellbeing state on their farming systems in general, and on the adoption level of these two technologies in Godohou village （southern Benin）. The data analysis revealed that： There was no significant difference between the farmers＇ amount knowing the agronomic and ecological value of Mucuna pruriens and Acacia auriculiformis from a level of prosperity to another; Three wealth levels were distinguished： The poor class （Ayatonon class）, the less poor class （Metchivo-Houedeka class） and the non poor class （Hotonon class） which represented respectively 35.4%, 55.9% and 8.7%;The adoption rate of Mucuna and Acacia fallow was globally low in Godohou village （25.7%）, but this adoption rate was lesser in the poorest class than in all other classes. This trend was confirmed if we integrate a global agro-ecological analysis of the farming systems practiced by the farmers.

关键词： Godohou poverty environment mucuna acacia adoption level of prosperity.

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Combinatorial Complexity in a Transcriptionally Centered Signaling Hub in Arabidopsis

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Molecular Plant 2014年第11期7卷 1598-1618页

作者： anne Pfeiffer Department of Plant and Microbial Biology University of California Berkeley CA 94720 USA United States Department of Agriculture Plant Gene Expression Center Albany CA 94710 USA

A subfamily of four Phytochrome （phy）-Interacting bHLH transcription Factors （PIFs） collectively promote skotomorphogenic development in dark-grown seedlings. This activity is reversed upon exposure to light, by photoacti- vated phy molecules that induce degradation of the PIFs, thereby triggering the transcriptional changes that drive a tran- sition to photomorphogenesis. The PIFs function both redundantly and partially differentially at the morphogenic level in this process, To identify the direct targets of PIF transcriptional regulation genome-wide, we analyzed the DNA-binding sites for all four PIFs by ChlP-seq analysis, and defined the genes transcriptionally regulated by each PIF, using RNA-seq analysis of pif mutants. Despite the absence of detectable differences in DNA-binding-motif recognition between the PIFs, the data show a spectrum of regulatory patterns, ranging from single PIF dominance to equal contributions by all four. Similarly, a broad array of promoter architectures was found, ranging from single PIF-binding sites, containing single sequence motifs, through multiple PIF-binding sites, each containing one or more motifs, with each site occupied prefer- entially by one to multiple PIFs. Quantitative analysis of the promoter occupancy and expression level induced by each PIF revealed an intriguing pattern. Although there is no robust correlation broadly across the target-gene population, examination of individual genes that are shared targets of multiple PIFs shows a gradation in correlation from strongly positive, through uncorrelated, to negative. This finding suggests a dual-layered mechanism of transcriptional regulation, comprising both a continuum of binding-site occupancy by each PIF and a superimposed layer of local regulation that acts differentially on each PIF, to modulate its intrinsic transcriptional activation capacity at each site, in a quantitative pattern that varies between the individual PIFs from gene to gene. These findings pr

关键词： phytochromes light-signaling PIFs bHLH transcription factors promoter occupancy Arabidopsis transcrip-tional regulation ChlP-seq RNA-seq.

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ESTIMATION AND UNCERTAINTY QUANTIFICATION FOR PIECEWISE SMOOTH SIGNAL RECOVERY

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Journal of Computational Mathematics 2023年第2期41卷 246-262页

作者： Victor Churchill anne Gelb Department of Mathematics The Ohio State UniversityColumbusOHUSA Department of Mathematics Dartmouth CollegeHanoverNHUSA

This paper presents an application of the sparse Bayesian learning(SBL)algorithm to linear inverse problems with a high order total variation(HOTV)sparsity *** the problem of sparse signal recovery,SBL often produces more accurate estimates than maximum a posteriori estimates,including those that useℓ1 ***,rather than a single signal estimate,SBL yields a full posterior density estimate which can be used for uncertainty ***,SBL is only immediately applicable to problems having a direct sparsity prior,or to those that can be formed via *** paper demonstrates how a problem with an HOTV sparsity prior can be formulated via synthesis,and then utilizes *** expands the class of problems available to Bayesian learning to include,e.g.,inverse problems dealing with the recovery of piecewise smooth functions or signals from *** examples are provided to demonstrate how this new technique is effectively employed.

关键词： High order total variation regularization Sparse Bayesian learning Analysis and synthesis Piecewise smooth function recovery

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GREEN ROOFING IN INDIANA: CASE STUDIES AND DESIGN NOTES

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Journal of Green Building 2010年第3期5卷 50-68页

作者： anne Altor Tierra Verde Consulting

Green roof technology and implementation are taking root in North America at an accelerating *** recogni-tion of the benefits of green roofs and increasing interest in green infrastructure are leading to expansion of green roof tech-nologies that have been in use for decades in Europe and *** some regions have adopted the use of green roofs on a large scale,other areas are warming up to the concept more ***-scale implementation of green roofs has not yet occurred in Indiana,but a number of exemplary projects have been constructed,and there are signs that interest in the technology is increasing in the *** purpose of this article is to provide an overview of green roof technology,analyze selected green roofs in Indiana,explore trends in the state,and address issues for future development of green roof technol-ogy in the region.A variety of green roofs were investigated throughout the *** were held with individuals involved in each project to obtain technical and logistical details of green roof design,installation,and performance.

关键词： green roof technology green roof design and installation green roof maintenance and performance stormwater management modular versus loose laid systems energy efficiency

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Cellulose Synthases and Synthesis in Arabidopsis

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Molecular Plant 2011年第2期4卷 199-211页

作者： anne Endler Staffan Persson Max-Planck-Institute for Molecular Plant Physiology Am M6hlenberg 1 14476 Potsdam Germany

Plant cell walls are complex structures composed of high-molecular-weight polysaccharides, proteins, and lignins. Among the wall polysaccharides, cellulose, a hydrogen-bonded β-1,4-1inked glucan microfibril, is the main load-bearing wall component and a key precursor for industrial applications. Cellulose is synthesized by large multi-meric cellulose synthase （CesA） complexes, tracking along cortical microtubules at the plasma membrane. The only known components of these complexes are the cellulose synthase proteins. Recent studies have identified tentative interaction partners for the CesAs and shown that the migratory patterns of the CesA complexes depend on phosphorylation status. These advances may become good platforms for expanding our knowledge about cellulose synthesis in the near future. In addition, our current understanding of cellulose chain polymerization in the context of the CesA complex is discussed.

关键词： Cell expansion cell walls cytoskeleton-cell wall interactions Arabidopsis.

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Isoform-and cell-state-specific APOE homeostasis and function

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Neural Regeneration Research 2024年第11期19卷 2456-2466页

作者： Karina Lindner anne-Claude Gavin Department of Cell Physiology and Metabolism Faculty of MedicineUniversity of GenevaGenevaSwitzerland Diabetes Center Faculty of MedicineUniversity of GenevaGenevaSwitzerland

Apolipoprotein E is the major lipid transporter in the brain and an important player in neuron-astrocyte metabolic *** ensures the survival of neurons under stressful conditions and hyperactivity by nourishing and detoxifying *** E polymorphism,combined with environmental stresses and/or age-related alterations,influences the risk of developing late-onset Alzheimer’s *** this review,we discuss our current knowledge of how apolipoprotein E homeostasis,*** synthesis,secretion,degradation,and lipidation,is affected in Alzheimer’s disease.

关键词： Alzheimer’s disease apolipoprotein E autophagy cholesterol lipid detoxification lipid transport lysosomal failure metabolic impairment triacylglycerol

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Science Fiction as a Manifestation of Culture in America

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外国文学研究 2005年第6期27卷 41-47页

作者： Elizabeth anne Hull William Rainey Harper College USA

Culture is broadly viewed as all the human activities that define us as a species. ″Sturgeon’s Law″ (that 90% of everything is inferior) is introduced to defend the study of fiction, and science fiction in particular, in higher education as a way of understanding ourselves better, and perhaps improving the world through the increased understanding of tomorrow’s leaders. Several ways of reading particular works of science fiction are examined, like providing historical contexts for readers, close reading and structural analysis, and application of theories based on particular ideologies or from other disciplines in the social and political sciences (such as feminist theory, Marxist theory, psychological theory, etc.). A conclusion is drawn that for literary analysis, a hybrid methodology, one devised individually for each text, works best.

关键词：科学小说美国文学研究文化背景

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