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Application of Pomegranate Rind Extract for Improvement of Functional Properties of Various Materials—A Critical Review

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Open Journal of Composite Materials 2024年第2期14卷 71-90页

作者： Habeebunissa Nooman Narayanan Gokarneshan Murugan Umamaheswari Muthumani Dhiliphan Kumar Usha Kumari Ratna Jayagopal Lavanya Senthamarai Kannan Umamageshwari Sona mohandas Anton Zahurudeen Shahanaz Venkatesan Sathya David Piriadarshani Chokkanathan Kayalvizhi Department of Knitwear Design National Institute of Fashion Technology Chennai India Department of Textile Chemistry SSM College of Engineering Komarapallayam India Department of Management Studies Dr. SNS Rajalakshmi College of Arts and Science Coimbatore India Department of Business Administration Kalasalingam Business School Kalasalingam Academy of Research and Education Srivilliputhur India Department of Textiles and Clothing Avinashi Lingam Institute for Home Science and Higher Education for Women Coimbatore India Department of Fashion Design SRM Institute of Science and Technology (Kattankalathur) Chennai India Department of Fashion Design Hindustan Institute of Technology and Science Chennai India Department of Fashion Design SRM Institute of Science and Technology (Ramapuram) Chennai India Department of Mathematics Hindustan Institute of Technology and Science Chennai India Department of Textile Technology Jaya Engineering College Tiruninravur India

Pomegranate rind is abundantly available as a waste material. Pomegranate Rind Extract (PRE) can be applied to cotton fabrics for its natural colours, as a mordanting agent and also for imparting certain functional properties such as fire retardancy and antimicrobial properties. This paper reviews the feasibility of Pomegranate Rind Extract to improve the functional properties of cellulosic fabrics. Studies show that varying concentrations and higher temperatures that were used to apply the extract on the fabric, resulted in enhanced functional properties. At a particular concentration, the treated fabric showed a 15 times lower burning rate in comparison with the control fabric. Also, antimicrobial efficacy has been observed against Gram-positive and Gram-negative bacteria. Due to the natural colouring material, it can be used as a natural dye on cotton material. The fire retardancy of pomegranate rind extract was tested on jute material under varying alkalinity. Research has indicated that pomegranate rind extract could be used to dye polyamide as well. The rubbing and wash fastness of the finished fabrics is good. The light fastness was fair, and its antibacterial efficiency against tested bacteria was good.

关键词： Natural Polymers Synthetic Polymers Pomegranate Rind Extract (PRE) Dyeing Functional Property

Role of pregnane X-receptor in regulating bacterial translocation in chronic liver diseases

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World Journal of Hepatology 2017年第32期9卷 1210-1226页

作者： Sundhar mohandas Balasubramaniyan Vairappan Liver Diseases Research Lab Department of BiochemistryJawaharlal Institute of Postgraduate Medical Education and ResearchDhanvantari NagarPondicherry 605006India

Bacterial translocation(BT) has been impeccably implicated as a driving factor in the pathogenesis of a spectrum of chronic liver diseases(CLD). Scientific evidence accumulated over the last four decades has implied that the disease pathologies in CLD and BT are connected as a loop in the gut-liver axis and exacerbate each other. Pregnane X receptor(PXR) is a ligandactivated transcription factor and nuclear receptor that is expressed ubiquitously along the gut-liver-axis. PXR has been intricately associated with the regulation of various mechanisms attributed in causing BT. The importance of PXR as the mechanistic linker molecule in the gutliver axis and its role in regulating bacterial interactions with the host in CLD has not been explored. Pub Med was used to perform an extensive literature search using the keywords PXR and bacterial translocation, PXR and chronic liver disease including cirrhosis. In an adequate expression state, PXR acts as a sensor for bile acid dysregulation and bacterial derived metabolites, and in response shapes the immune profile beneficial to the host. Activation of PXR could be therapeutic in CLD as it counter-regulates endotoxin mediated inflammation and maintains the integrity of intestinal epithelium. This review mainly focuses PXR function and its regulation in BT in the context of chronic liver diseases.

关键词： Pregnane X receptor Bacterial translocation Chronic liver disease Intestinal permeability Inflammation Tight junctions

Surviving the odds: From perception to survival of fungal phytopathogens under host-generated oxidative burst

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Plant Communications 2021年第3期2卷 38-54页

作者： Yeshveer Singh Athira mohandas Nair Praveen Kumar Verma Plant Immunity Laboratory National Institute of Plant Genome ResearchAruna Asaf Ali MargNew Delhi 110067India School of Life Sciences Jawaharlal Nehru UniversityNew Delhi 110067India

Fungal phytopathogens pose a serious threat to global crop *** a handful of strategies are available to combat these fungal infections,and the increasing incidence of fungicide resistance is making the situation ***,the molecular understanding of plant–fungus interactions remains a primary focus of plant *** of the hallmarks of host–pathogen interactions is the overproduction of reactive oxygen species(ROS)as a plant defense mechanism,collectively termed the oxidative *** general,high accumulation of ROS restricts the growth of pathogenic organisms by causing localized cell death around the site of *** survive the oxidative burst and achieve successful host colonization,fungal phytopathogens employ intricate mechanisms for ROS perception,ROS neutralization,and protection from ROS-mediated ***,these countermeasures maintain the physiological redox homeostasis that is essential for cell *** addition to intracellular antioxidant systems,phytopathogenic fungi also deploy interesting effector-mediated mechanisms for extracellular ROS *** aspect of plant–pathogen interactions is significantly under-studied and provides enormous scope for future *** adaptive responses,broadly categorized into“escape”and“exploitation”mechanisms,are poorly *** this review,we discuss the oxidative stress response of filamentous fungi,their perception signaling,and recent insights that provide a comprehensive understanding of the distinct survival mechanisms of fungal pathogens in response to the host-generated oxidative burst.

关键词： reactive oxygen species(ROS) oxidative stress response fungal effectors stress signaling plant-pathogen interactions

Factors Influencing the Direct Electrochemical Reduction of Nb_2O_5 Pellets to Nb Metal in Molten Chloride Salts

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Acta Metallurgica Sinica(English Letters) 2017年第3期30卷 218-227页

作者： D.Sri Maha Vishnu N.Sanil K.S.mohandas K.Nagarajan Chemistry Group Indira Gandhi Centre for Atomic Research Materials Chemistry Group Department of Materials Science and MetallurgyUniversity of Cambridge

Powder compacted and sintered Nb205 pellets were cathodically polarised against graphite anode in calcium chloride melt at 1173 K to study the influence of various factors on the electrochemical reduction of the oxide. The parameters were; duration and temperature of electrolysis, open porosity of pellets, nature of anode, mode of electrolysis and configuration of the oxide cathode. The experiments were also conducted in KC1, KC1-25 tool% CaC12 and NaC1 melts to understand the effect of melt composition on the electroreduction. Different Ca-Nb-O and Nb-O intermediates were found in the pellets electrolysed for different durations of time in CaC12 melt which eventually reduced to Nb. The current efficiency of the process decreased with increasing duration of electrolysis. Decrease in electrolysis temperature from 1 173 to 1073 K led to the decrease in the rate of reduction of the oxide pellets. Pellets with high open porosity reduced faster. Carbon contamination of the melt was relatively less when pyrolytic graphite was used as anode. Of all the melts studied, the reduction was found to be better in calcium chloride melt, that too when alumina crucible was used as container of the melt.

关键词： Fray-Farthing-Chen (FFC) Cambridge process Electrochemical reduction Open porosity Niobium pentoxide Calcium chloride

Interplay between cofactors and transcription factors in hematopoiesis and hematological malignancies

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Signal Transduction and Targeted Therapy 2021年第2期6卷 409-424页

作者： Zi Wang Pan Wang Yanan Li Hongling Peng Yu Zhu Narla mohandas Jing Liu Department of Hematology Istitute of Molecular HematologyThe Second Xiangya HospitalCentral South University41001 ChangShaHunanChina Molecular Biology Research Center and Hunan Province Key Laboratory of Basic and Applied Hematology School of Life SciencesCentral South University410078 ChangshaHunanChina Red Cell Physiology Laboratory New York Blood CenterNew YorkNYUSA

Hematopoiesis requires finely tuned regulation of gene expression at each stage of *** regulation of gene transcription involves not only individual transcription factors(TFs)but also transcription complexes(TCs)composed of transcription factor(s)and multisubunit *** their normal compositions,TCs orchestrate lineage-specific patterns of gene expression and ensure the production of the correct proportions of individual cell lineages during *** integration of posttranslational and conformational modifcations in the chromatin landscape,nucleosomes,histones and interacting components via the cofactor-TF interplay is critical to optimal TF *** or translocations of cofactor genes are expected to alter cofactor-TF interactions,which may be causative for the pathogenesis of various hematologic *** TF oncogenic activity in hematologic disorders through targeting cofactors in aberrant complexes has been an exciting therapeutic *** this review,we summarize the current knowledge regarding the models and functions of cofactor-TF interplay in physiological hematopoiesis and highlight their implications in the etiology of hematological *** review presents a deep insight into the physiological and pathological implications of transcription machinery in the blood system.

关键词： hematopoiesis cofactor landscape

Influence of process parameters on physical dimensions of AA6063 aluminium alloy coating on mild steel in friction surfacing

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Defence Technology（防务技术） 2015年第3期11卷 275-281页

作者： B.VIJAYA KUMAR G.MADHUSUDHAN REDDY T.mohandas Department of Mechanical Engineering Guru Nanak Institute of Technology Defence Metallurgical Research Laboratory Department of Mechanical Engineering Nalla Malla Reddy Engineering College

An attempt is made in the present study to obtain the relationships among process parameters and physical dimensions of AA6063 aluminium alloy coating on IS2062 mild steel obtained through friction surfacing and their impact on strength and ductility of the coating. Factorial experimental design technique was used to investigate and select the parameter combination to achieve a coating with adequate strength and ductility. Spindle speed, axial force and table traverse speed were observed to be the most significant factors on physical dimensions. It was observed that the thickness of the coating decreased as the coating width increased. In addition, the width and thickness of the coatings are higher at low and high torques. At intermediate torque values, when the force is high, the width of the coating is high, and its thickness is thin; and when the force is low, the width and thickness are low. The interaction effect between axial force(F)-table traverse speed(Vx) and spindle speed(N)-table traverse speed(Vx) produced an increasing effect on coating width and thickness, but other interactions exhibited decreasing influence. It has also been observed that sound coatings could be obtained in a narrow set of parameter range as the substrate-coating materials are metallurgically incompatible and have a propensity to form brittle intermetallics.

关键词：合金涂层摩擦表面尺寸物理工艺参数碳钢涂层厚度试验设计技术

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临床心电学杂志 2024年第2期33卷 F0003-F0003页

作者：圣雄甘地不详

Is the erythropoietin receptor the key to the identification of the central macrophage in erythroblastic islands?

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Blood Science 2020年第1期2卷 38-39页

作者： Lionel Blanc Narla mohandas Laboratory of Developmental Erythropoiesis Department of Molecular Medicine and PediatricsThe Feinstein Institute for Medical ResearchZucker School of Medicine at Hofstra/NorthwellManhassetNY 11030USA Red Cell Physiology Laboratory New York Blood CenterNew YorkNY 10065USA

Erythroblastic islands(EBI)are niches for mammalian erythropoiesis.1 They were first identified in 1958 by Marcel Bessis and consist of a group of differentiating erythroblasts surrounding a central macrophage.2 Over the years,a lot of attention has been paid to understand the role of the central macrophage in regulating the differentiation of the maturing erythroblasts within these islands and in defining the surface proteins thatmediate the interaction between the erythroblasts and the centralmacrophage.3–14While some progress has beenmade in these areas of investigation,the definitive identity of this central macrophage and its function is yet to be fully characterized.

关键词： macrophage. blastic interaction

Efficient Data Integrity Using Enhanced Secret Sharing Scheme for MANET

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Circuits and Systems 2016年第10期7卷 3174-3182页

作者： R. mohandas Rengaraju K. Krishnamoorthi Department of Electronics and Communication Engineering Jayaram College of Engineering Trichy India Department of Electrical Engineering Sona College of Technology Salem India

Mobile Ad Hoc Networks consist of nodes which are wireless and get organized based on the transmission requirement. These nodes are mobile nodes, so they communicate with each other without any fixed access point. This type of network faces several attacks because of its mobility nature. In MANET, black hole attacks may cause packet dropping or misrouting of packets during transmission from sender to receiver. This may lead to performance degradation in the network. To surmount this issue, we propose the modified secret sharing scheme to provide the data protection from unauthorized nodes, consistency of data and genuineness. In this algorithm, initially the identification of black hole attacks is achieved and followed by data protection from malicious nodes and also this scheme checks for the reality of the data. Here, we detect the misbehaviour that is dropping or misrouting using verifiable secret sharing scheme. The proposed algorithm achieves the better packet delivery ratio, misbehaviour detection efficiency, fewer packets overhead and end-to-end delay than the existing schemes. These can be viewed in the simulation results.

关键词： MANET Verifiable Secret Sharing Modified Proactive Secret Sharing Scheme End-to-End Delay Overhead Misbehaviour Detection Efficiency and Delivery Ratio