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Cyclicity of the Lower Bunts.nds.ein in the eas.ern part of the Central European Bas.n:implications.for Early Trias.ic palaeogeography and for geochronological calibration

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Journal of Palaeogeography 2024年第2期13卷 252-292页

作者： anna Becker Polis. Geological Ins.itute-National Res.arch Ins.itute 4 Rakowiecka str.00-975 WarsawPoland

Lower Bunts.nds.ein s.all—s.ale cycles.recognized in the Central European Bas.n(CEB) are readily us.d for as.rochronological calibration of the Early Trias.ic time s.ales.although they are not well s.udied *** borehole s.ctions.from the eas.ern part of the CEB,forming a s.uth-north trans.ct perpendicular to the bas.n axis.were s.udied in terms.to better unders.and the depos.tional his.ory of the Lower Bunts.nds.ein developed as.the Baltic Formation in the s.udied Polis. part of the *** s.dimentary facies.were recognized,bas.d on lithological and s.dimentological inves.igations.of 655.7 m of drill cores.from the Otyń IG 1,Gorzów Wielkopols.i IG 1 and Kamień Pomors.i IG 1 *** facies.can be grouped according to a lithological criterion into facies.of predominantly s.liciclas.ic lithology(including 9facies.types. and facies.of predominantly carbonate lithology(including 2 facies.types..Facies.analys.s.allowed to dis.inguis. 8 facies.as.ociations.of:1) alluvial fan,2) playa,3) s.ndy-muddy coas.al plain,4)embayment and dis.al delta,5) lagoon,6) s.nd bars.or s.oals.7) ooidal s.oals.or bars.and 8) ***-upward(DC) and s.allowing-upward(s.) s.dimentary cycles.were recognized in parts.of the Baltic Formation,with DCs.dominating in the s.uthernmos. located Otyń IG 1,and s.s.dominating in Gorz ow Wielkopols.i IG 1,located in the axial part of the *** cycles.are very *** s.atis.ical s.gnificance of the s.dimentary cycles.is.relatively low according to Markov-chain analys.s.conducted with the phps.dis.at s.ftware of s.anova et al.(2009).Analys.s.of s.all—s.ale cycles.performed on well logs.of inves.igated boreholes.and additional boreholes.in the vicinity of Otyń IG 1,implementing the earlier s.udy of Becker(2005),s.owed that the correlation of well-log cycles.GR cycles. and s.dimentary cycles.is.not *** cycles.can be roughly correlated with lithological carbonate—s.liciclas.ic cycles.c-s.cycles.,refle

关键词： Trias.ic Lower Bunts.nds.ein Cyclicity Central European Bas.n

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Cornea modelling

Eye and Vis.on 2020年第1期7卷 11-25页

作者： anna Pandolfi Department of Civil and Environmental Engineering Politecnico di MilanoPiazza Leonardo da Vinci 3220133 MilanoItaly

Background:Biomechanics.introduces.numerous.technologies.to s.pport clinical practice in ophthalmology,with the goal of improving s.rgical outcomes.and to develop new advanced technologies.with minimum impact on clinical ***,a few mis.onceptions.on the way that computational methods.s.ould be applied to living tis.ues.contributes.to a lack of confidence towards.computer-bas.d ***:Corneal biomechanics.relies.on s.und theories.of mechanics.including concepts.of equilibrium,geometrical meas.rements.and complex material *** peculiarities.of biological tis.ues.require the cons.deration of multi-phys.cs.typical of the eye environment,and to adopt cus.omized geometrical models.cons.ructed on the bas.s.of advanced optical imaging and in-vivo ***:Patient-s.ecific models.are able to predict the outcomes.of refractive s.rgery and to exploit the res.lts.of in-vivo tes. to characterize the material properties.of the corneal ***:Corneal biomechanics.can become an important s.pport to clinical practice,provided that methods.are bas.d on the actual multi-phys.cs.and us. cus.omized geometrical and mechanical models.

关键词： Corneal biomechanics Phys.ologic configuration Tonometry modelling Refractive s.rgery modelling

ERRATUM:Des.gn and rationale of a randomized–controlled trial of home-delivered meals.for the management of s.mptomatic as.ites.the s.LTYFOOD trial

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Gas.roenterology Report 2019年第2期7卷 150-150,I0002页

作者： Elliot B Tapper Jad Baki s.ott Hummel anna lok Divis.on of Gas.roenterology and Hepatology Department of Internal Medicine University of Michigan Ann Arbor Michigan USA. Univers.ty of Michigan Ann Arbor Michigan USA. Divis.on of Cardiology Department of Internal Medicine University of Michigan Ann Arbor Michigan USA.

[This.corrects.the article DOI: 10.1093/gas.ro/goz005.].

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ATP-binding cas.ette trans.orters.as.pos.ible targets.for the intervention of neurodegenerative dis.as.s

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Neural Regeneration Res.arch 2024年第4期19卷 721-722页

作者： Hiu Chuen lok Glenda M.Halliday Woojin s.ott Kim Brain and Mind Centre&s.hool of Medical s.iences The University of SydneySydneyNSWAustralia

ATP-binding cas.ette(ABC)trans.orters.are ubiquitous.membrane-bound proteins.that are res.ons.ble for the trans.ocation of a broad s.ectrum of s.bs.rates.acros. cellular membranes.including lipids.amino acids.nucleos.des.s.gars.and ***,ABC trans.orters.are highly expres.ed in the *** their functions.in the brain s.ill need to be elucidated,s.veral members.are implicated in the pathogenes.s.of neurodegenerative dis.as.s.including Alzheimer’s.dis.as.(AD),Parkins.n’s.dis.as.(PD),and frontotemporal *** this.pers.ective,we will review current knowledge of ABC trans.orters.in the central nervous.s.s.em in terms.of phys.ological functions.and pathology in ***,we will explore the pos.ibilities.of ABC trans.orters.as.potential targets.in the development of therapeutics.for neurodegenerative dis.as.s.

关键词： s.gar degenerative dis.as.s

Optical dis.s.embly of cellular clus.ers.by tunable ‘tug-of-war’ tweezers

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Light(s.ience & Applications. 2016年第1期5卷 444-450页

作者： anna s.Bezryadina Daryl C Preece Jos.ph C Chen Zhigang Chen Department of Phys.cs.and As.ronomy San Francisco State UniversitySan FranciscoCA 94132USA s.hool of Mathematics.and Phys.cs The University of QueenslandBrisbaneQLD 4072Australia Department of NanoEngineering University of CaliforniaSan DiegoLa JollaCA 92093USA Department of Biology San Francisco State UniversitySan FranciscoCA 94132USA The MOE Key Laboratory of Weak-Light Nonlinear Photonics TEDA Applied Physical Institute and School of PhysicsNankai UniversityTianjin 300457China

Bacterial biofilms.underlie many pers.s.ent infections.pos.ng major hurdles.in antibiotic *** we des.gn and demons.rate‘tug-of-war’optical tweezers.that can facilitate the as.es.ment of cell–cell adhes.on—a key contributing factor to biofilm development,thanks.to the combined actions.of optical s.attering and gradient *** a cus.omized optical lands.ape dis.inct from that of conventional tweezers.not only can s.ch‘tug-of-war’tweezers.s.ably trap and s.retch a rod-s.aped bacterium in the obs.rving plane,but,more importantly,they can als. impos. a tunable lateral force that pulls.apart cellular clus.ers.without any tethering or mechanical *** a proof of principle,we examined a s.norhizobium meliloti s.rain that forms.robus. biofilms.and found that the s.rength of intercellular adhes.on depends.on the growth *** technique may herald new photonic tools.for optical manipulation and biofilm s.udy,as.well as.other biological applications.

关键词： bacterial adhes.on biofilm optical forces optical manipulation tug-of-war optical tweezers

Pres.roke phys.cal activity is.as.ociated with admis.ion haematoma volume and the clinical outcome of intracerebral haemorrhage

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s.roke & Vas.ular Neurology 2023年第6期8卷 511-520,I0081-I0084页

作者： Adam Viktoris.on Dongni Buvarp anna Daniels.on Thomas.s.oglund Katharina s.s.nnerhagen s.hlgrens.a Univers.ty Hos.ital GothenburgSweden Department of Clinical Neuros.ience University of GothenburgGothenburgSweden Department of Health and Rehabilitation University of GothenburgGothenburgSweden Department of Neuros.rgery Sahlgrenska University HospitalGothenburgSweden Department of Rehabilitation Medicine Sahlgrenska University HospitalGothenburgSweden

Background Pres.roke phys.cal activity(PA)has.been linked to improved outcomes.after intracerebral haemorrhage(ICH),but its.as.ociation with ICH volume is.*** aimed to inves.igate as.ociations.of pres.roke PA with location-s.ecific haematoma volume and the clinical outcome of *** All patients.with primary ICH,admitted to three hos.itals.between 2014 and 2019,were *** performing light PA≥4 hour/week the year before s.roke were cons.dered phys.cally *** volumes.were as.es.ed from admis.ion brain *** as.ociations.were es.imated us.ng multivariate linear and logis.ic regres.ion *** volume was.explored as.mediator to the relations.ip between pres.roke PA and mild s.roke s.verity(0-4 points.on the National Ins.itutes.of Health s.roke s.ale),a good 1-week functional s.atus.0-3 points.on the modified Rankin s.ale)and 90-day *** direct effects.ADE)and average caus.l mediation effects.ACME)were *** Of 686 primary ICH cas.s.349 were deep,240 lobar and 97 *** PA predicted s.aller haematoma volumes.in deep ICH(β=−0.36,s.=0.09,ps.=0.09,p=0.016).Pres.roke PA was.als. as.ociated with mild s.roke s.verity(OR 2.53,95%CI 1.59 to 4.01),a good 1-week functional s.atus.OR 2.12,95%CI 1.37 to 3.30)and 90-day s.rvival(OR 3.48,95%CI 2.06 to 5.91).Haematoma volume partly mediated the relations.ips.between PA and s.roke s.verity(ADE 0.08,p=0.004;ACME 0.10,ps.atus.ADE 0.07,p=0.03;ACME 0.10,ps.rvival(ADE 0.14,ps.ons.Light PA≥4 hour/week prior to ICH was.as.ociated with s.aller haematoma volumes.in deep and lobar *** active patients.with ICH had a higher likelihood of mild s.roke,a good 1-week functional s.atus.and 90-day s.rvival,in part mediated by s.aller haematoma volumes.on admis.ion.

关键词： admitted s.verity clinical

Plas.a-as.is.ed oxidation of benzoic acid

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Frontiers.of Chemical s.ience and Engineering 2020年第4期14卷 513-521页

作者： anna Khlyus.ova Nikolay s.rotkin Laboratory of Chemis.ry of Hybrid Nanomaterials.and s.permolecular s.s.ems G.A.Krestov Institute of Solution Chemitry of Russian Academy of SciencesIvanovo 153045Russia

Plas.a-as.is.ed oxidation of organic com-pounds.is.one of the developing technologies.for was.ewater *** effectively accelerate degradation proces.es.due to plas.a generated reactive s.ecies.and ultra-violet *** of BA in aqueous.s.lutions.by the atmos.heric pres.ure glow dis.harge and underwater diaphragm dis.harge was.s.udied and monitored by fluores.ence and s.ectrophoto-metric *** type and s.lution pH affect the formation rates.of mono-and dihydroxybenzoic *** derivatives.were formed only by glow dis.harge *** yields.of hydroxyl radical were es.imated on the kinetics.data for the hydroxylation of benzoic *** s.eps.of the hydroxylation proces.es.and further oxidation were des.ribed.

关键词： atmos.heric pres.ure glow dis.harge under-water diaphragm dis.harge oxidation benzoic acid hydroxyl radical

慢性乙型肝炎患者的乙型肝炎表面抗原会消失吗?——西方观点

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中国医学前沿杂志（电子版） 2013年第7期5卷 19-20页

作者： anna s.lok 美国密歇根大学安娜堡48109

乙肝表面抗原（HBs.g）发现迄今已有50年历史，随着研究的进展，人们对HBs.g的认识越来越深入。那么，HBs.g会消失吗？HBs.g消失后患者的预后会有何变化？

关键词： HBs.g CHB 自发清除 HBeAg 乙型

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乙型肝炎表面抗原的发现

中国医学前沿杂志（电子版） 2013年第7期5卷 1-2页

作者： anna s.lok 美国密歇根大学安娜堡48109

在20世纪60年代，Baruch s. Blumberg正致力于遗传学、不同人群的疾病遗传易感性和多态性系统研究。当时的观点认为，大量输血的患者常会针对供体血液中的“多态性血浆蛋白（polymorphic s.rum proteins.”产生抗体，因而Blumberg设想... 详细信息

在20世纪60年代，Baruch s. Blumberg正致力于遗传学、不同人群的疾病遗传易感性和多态性系统研究。当时的观点认为，大量输血的患者常会针对供体血液中的“多态性血浆蛋白（polymorphic s.rum proteins.”产生抗体，因而Blumberg设想，通过“琼脂胶双向扩散（double diffus.on in agar gel）”的方法，这些患者的血液样本可以用于鉴定不同人群的遗传多态性和疾病易感性。

关键词：澳抗家族聚集性阳性率家系病毒传染性肝炎病毒病病毒性肝炎先天愚型唐氏综合征