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Journal of Forestry Research 2022年第4期33卷 1365-1375页

作者： Cecilia Laurell Torkel Berglund anna B.Ohlsson Department of Industrial Biotechnology School of Engineering Sciences in ChemistryBiotechnology and Health(CBH)KTH Royal Institute of Technology10691 StockholmSweden

Nicotinamide treatment of plants and plant cell cultures has been shown to promote defense and decrease levels of DNA *** the present study,we used RNA-seq technology to study overall changes in gene expression induced in roots of 3-month-old spruce(Picea abies)seedlings grown from nicotinamide-treated seeds to examine the molecular mechanisms underlying the defense *** 350 genes were identified as differentially expressed in roots after the seed *** response genes,including transcription factors MYB77 and LHY and two chitinase enzymes,were generally upregulated,whereas genes thought to be involved in epigenetic regulation such as DDM1,known to promote DNA methylation,were present at high frequency among the downregulated *** all samples,the expression of downregulated epigenetic-related genes was highly correlated with the nicotinamide treatment,indicating a common *** results support an earlier hypothesis regarding a potential role of nicotinamide as a defense-signal mediator.

关键词： DNA methylation Large-scale gene expression analysis Nicotinamide Picea abies Seed treatment

Borderline resectable pancreatic cancer and vascular resections in the era of neoadjuvant therapy

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World Journal of Clinical Cases 2021年第20期9卷 5398-5407页

作者： Danko Mikulic anna Mrzljak Department of Surgery University Hospital MerkurZagreb 10000Croatia Department of Gastroenterology and Hepatology University Hospital Center ZagrebZagreb 10000Croatia

While pancreatic cancer is still characterized by early systemic spread and poor outcomes,the treatment of this disease has changed significantly in recent years due to major advancements in systemic therapy and advanced surgical *** use of effective neoadjuvant approaches combined with aggressive surgical operations within a multidisciplinary setting has improved *** resectable pancreatic cancer is characterized by tumor vascular invasion,and is a setting where the combination of potent neoadjuvant chemotherapy and aggressive surgical methods,including vascular resections and reconstructions,shows its full ***,this will lead to improved local control and curative treatment in a number of patients with this aggressive malignancy.

关键词： Pancreatic adenocarcinoma Borderline resectable Neoadjuvant therapy Venous resection Arterial resection Vascular reconstruction

Thermal Efficiency Optimization of a Ground Source Heat Pump System by Assistant Preheating/Precooling: A Case Study on a Heating-Load Dominated Building

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Journal of Thermal Science 2022年第6期31卷 1948-1958页

作者： LUO Jin ZHANG Qi PRIESS anna ROHN Joachim Faculty of Engineering China University of Geosciences(Wuhan)Wuhan 430074China GeoZentrum Nordbayern University of Erlangen-NürnbergSchlossgarten 591054 ErlangenGermany

Operation strategies of Ground Source Heat Pump System(GSHPS) such as continuous or intermittent approaches have been extensively studied. In this work, a novel strategy was proposed to maximize the energy efficiency of GSHPS. In this approach, the buildings was first air-conditioned by the preheating/precooling mode and the rest thermal load was covered by the heat pump(HP) mode. The system performance can then be optimized by considering the combination of these two operating modes. A case study was made to examine the thermal performance of a GSHPS installed in Nuremberg, Germany. Thermal performance of the HP and the preheating/precooling operating modes was examined. The system was optimized by deploying the assistant preheating/precooling approach and over one-year period monitoring showed that the seasonal Coefficient of Performance(COP) of the GSHPS was 4.12 in winter and 5.01 in summer. These COP values are higher than that of the conventional GSHPS. Thus, this proposed strategy could be an efficient way to improve the thermal performance of GSHPS.

关键词： ground source heat pump system ground-air heat exchanger ground temperature response preheating and precooling

Polymerization of 1,3-Butadiene with Catalysts Based on Cobalt Dichloride Complexes with Aminophosphines: Switching the Regioselectivity by Varying the MAO/Co Molar Ratio

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Chinese Journal of Polymer Science 2024年第4期42卷 501-510页

作者： Giovanni Ricci anna Sommazzi Francesco Masi Alessandra Forni CNR-Istituto di Scienze e Tecnologie Molecolari“Giulio Natta”(SCITEC) via A.Corti 1220133MilanoItaly Viale Giovanni XXIII 34 I-28100NovaraNOItaly Via Galvani 7 I-26866Sant’Angelo LodigianoLOItaly CNR-Istituto di Scienze e Tecnologie Molecolari“Giulio Natta”(SCITEC) via C.Golgi 1920133MilanoItaly

Several novel cobalt dichloride complexes with amino-phosphine bidentate ligands were synthesized and *** some of them single crystals were obtained and their molecular structure was determined by X-ray diffraction *** the complexes were then used in combination with MAO for the polymerization of 1,3-butadiene,obtaining polymers with different structures(i.e.,predominantly 1,2 or cis-1,4)mainly depending on the type of ligand and on the MAO/Co molar *** behavior of these novel catalysts was compared with that exhibited,in the polymerization of the same monomer,by the systems CoCl_(2)(PR3)2-MAO and CoCl_(2)(PRPh2)2-MAO(R=alkyl or cycloalkyl group),and by the systems based on cobalt dichloride complexes with various bi-and tridentate ligands(e.g.,diphosphines,bis-imines,pyridyl-imines,bis-iminopyridines).The comparison between the different systems allowed us to make some clarity about the actual and effective role played by the various types of ligands in the polymerization of conjugated dienes with catalytic systems CoCl_(2)(L)-MAO,in which L=mono-,bi-,or tri-dentate ligand.

关键词： 1,3-Butadiene Stereospecific polymerization Cobalt catalysts Regioselectivity Aminophosphine ligands Crystal structures Chelate rings

Task-resource Scheduling Problem

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International Journal of Automation and computing 2012年第4期9卷 429-441页

作者： anna Gorbenko Vladimir Popov Department of Intelligent Systems and Robotics Ural State University

Cloud computing is a new and rapidly emerging computing paradigm where applications, data and IT services are provided over the Internet. The task-resource management is the key role in cloud computing systems. Task-resource scheduling problems are premier which relate to the efficiency of the whole cloud computing facilities. Task-resource scheduling problem is NP-complete. In this paper, we consider an approach to solve this problem optimally. This approach is based on constructing a logical model for the problem. Using this model, we can apply algorithms for the satisfiability problem (SAT) to solve the task-resource scheduling problem. Also, this model allows us to create a testbed for particle swarm optimization algorithms for scheduling workflows.

关键词： Clouds complexity theory scheduling satisfiability problem genetic algorithms

Imposing temporal consistency on deep monocular body shape and pose estimation

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Computational Visual Media 2023年第1期9卷 123-139页

作者： Alexandra Zimmer anna Hilsmann Wieland Morgenstern Peter Eisert Fraunhofer Heinrich-Hertz-Institut 10587 BerlinGermany Technische Universit¨at Berlin 10623 BerlinGermany Humboldt Universit¨at zu Berlin 10117 BerlinGermany

Accurate and temporally consistent modeling of human bodies is essential for a wide range of applications,including character animation,understanding human social behavior,and AR/VR *** human motion accurately from a monocular image sequence remains challenging;modeling quality is strongly influenced by temporal consistency of the captured body *** work presents an elegant solution to integrating temporal constraints during *** increases both temporal consistency and robustness during *** detail,we derive parameters of a sequence of body models,representing shape and motion of a *** optimize these parameters over the complete image sequence,fitting a single consistent body shape while imposing temporal consistency on the body motion,assuming body joint trajectories to be linear over short *** approach enables the derivation of realistic 3D body models from image sequences,including jaw pose,facial expression,and articulated *** experiments show that our approach accurately estimates body shape and motion,even for challenging movements and ***,we apply it to the particular application of sign language analysis,where accurate and temporally consistent motion modelling is essential,and show that the approach is well-suited to this kind of application.

关键词： motion capture surface reconstruction face modeling body model estimation

Magnesium acetyltaurate prevents retinal damage and visual impairment in rats through suppression of NMDA-induced upregulation of NF-κB,p53 and AP-1(c-Jun/c-Fos)

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Neural Regeneration Research 2021年第11期16卷 2330-2344页

作者： Lidawani Lambuk Igor Iezhitsa Renu Agarwal Puneet Agarwal anna Peresypkina anna Pobeda Nafeeza Mohd Ismail Center for Neuroscience Research(NeuRon) Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSelangorMalaysia School of Medicine International Medical UniversityKuala LumpurMalaysia Department of Pharmacology and Clinical Pharmacology Institute of MedicineBelgorod State National Research UniversityBelgorodRussia

Magnesium acetyltaurate(MgAT)has been shown to have a protective effect against N-methyl-D-aspartate(NMDA)-induced retinal cell *** current study investigated the involvement of nuclear factor kappa-B(NF-κB),p53 and AP-1 family members(c-Jun/c-Fos)in neuroprotection by MgAT against NMDA-induced retinal *** this study,Sprague-Dawley rats were randomized to undergo intravitreal injection of vehicle,NMDA or MgAT as pre-treatment to *** days after injections,retinal ganglion cells survival was detected using retrograde labelling with fluorogold and BRN3A *** outcome of retinal damage was assessed using electroretinography,and the mechanisms underlying antiapoptotic effect of MgAT were investigated through assessment of retinal gene expression of NF-κB,p53 and AP-1 family members(c-Jun/c-Fos)using reverse transcription-polymerase chain *** phospho-NF-κB,phospho-p53 and AP-1 levels were evaluated using western blot *** visual functions were evaluated using visual object recognition *** retrograde labelling and BRN3A immunostaining revealed a significant increase in the number of retinal ganglion cells in rats receiving intravitreal injection of MgAT compared with the rats receiving intravitreal injection of *** indicated that pre-treatment with MgAT partially preserved the functional activity of NMDA-exposed *** abolished NMDA-induced increase of retinal phospho-NF-κB,phospho-p53 and AP-1 expression and suppressed NMDA-induced transcriptional activity of NF-κB,p53 and AP-1 family members(c-Jun/c-Fos).Visual object recognition tests showed that MgAT reduced difficulties in recognizing the visual cues(*** with different shapes)after NMDA exposure,suggesting that visual functions of rats were relatively preserved by pre-treatment with *** conclusion,pre-treatment with MgAT prevents NMDA induced retinal injury by inhibiting NMDA-induced neuronal apoptosis via downr

关键词： AP-1(c-Jun/c-Fos) electroretinography magnesium acetyltaurate neuroprotection NF-κB N-methyl-D-aspartate object recognition tasks p53 retinal excitotoxicity retrograde labelling

Resilience:Lessons to be learned from safety and acceptable risk

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Journal of Safety Science and Resilience 2021年第4期2卷 253-257页

作者： Kosovac anna Tom McLeod Logan Faculty of Engineering and Information Technology The University of MelbourneAustralia Civil and Natural Resources Engineering The University of CanterburyNew Zealand

It is not unusual to see the concept of resilience housed in binary terms:Your city is either‘resilient’or *** contrast,being‘safe’is widely recognized as a statement based on‘acceptable risk’where absolute safety is *** why do we treat resilience and,as an example,the idea of“Resilient Cities”as a distinct endpoint?In this paper,we argue that this mindset is not only incongruent with current understandings of safety and risk but could create a false sense of security for systems that otherwise have been judged‘resilient’.An alternative is that we can and should consider framing resilience in the same manner as we do to *** benefit of doing this is that we can learn from the safety literature and appreciate that,like for safety,there is no such thing as absolute ***,we should be striving to constantly identify and reduce the risks to our systems and society.

关键词： Risk analysis Safety Risk assessment Resilient Resilience Urban Cities Disaster management

Functional and cognitive grammars

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外语教学与研究 2011年第5期43卷 643-664页

作者： anna Siewierska Lancaster University

This paper presents a comprehensive review of the functional approach and cognitive approach to the nature of language and its relation to other aspects of human *** paper starts with a brief discussion of the origins and the core tenets of the two approaches in Section *** 2 discusses the similarities and differences between the three full-fledged structural functional grammars subsumed in the functional approach:Halliday's Systemic Functional Grammar(SFG),Dik's Functional Grammar(FG),and Van Valin's Role and Reference Grammar(RRG).Section 3 deals with the major features of the three cognitive frameworks:Langacker's Cognitive Grammar(CG),Goldberg's Cognitive Construction Grammar(CCG),and Croft's Radical Construction Grammar(RCG).Section 4 compares the two approaches and attempts to provide a unified functional-cognitive *** the last section,the author concludes the paper with remarks on the unidirectional shift from functional grammar to cognitive grammar that may indicate a reinterpretation of the traditional relationship between functional and cognitive models of grammar.

关键词： functional grammar cognitive grammar

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中小学中国特色社会主义文化教育的实践路径

林区教学 2025年第1期 101-105页

作者：马安娜李传实山东中医药大学马克思主义学院

中小学中国特色社会主义文化教育，是推动中国特色社会主义文化建设的重要一环。根据中国特色社会主义文化的核心要义，中小学生文化教育应从价值引导力、文化凝聚力、精神推动力三个维度入手，在巩固社会主义核心价值观教育基础上，突... 详细信息

中小学中国特色社会主义文化教育，是推动中国特色社会主义文化建设的重要一环。根据中国特色社会主义文化的核心要义，中小学生文化教育应从价值引导力、文化凝聚力、精神推动力三个维度入手，在巩固社会主义核心价值观教育基础上，突出文化的自信自强精神，从学校、个人、社会三个方面强化中国特色社会主义文化教育。对中小学生进行中国特色社会主义文化教育，有助于学生培育和践行社会主义核心价值观，扎根中华优秀传统文化，增强文化自信，为建设社会主义文化强国奠定坚实基础。

关键词：中国特色社会主义文化中小学教育自信自强