检索结果-南通市图书馆

Cyclicity of the Lower Buntsandstein in the eastern part of the Central European Basin:implications for Early Triassic palaeogeography and for geochronological calibration

在线全文

学校读者我要写书评

暂无评论

Journal of Palaeogeography 2024年第2期13卷 252-292页

作者： anna Becker Polish Geological Institute-National res.arch Institute 4 Rakowiecka str.00-975 WarsawPoland

Lower Buntsandstein s.all—s.ale cycles recognized in the Central European Basin(CEB) are readily used for astrochronological calibration of the Early Triassic time s.ales.although they are not well studied *** borehole sections from the eastern part of the CEB,forming a south-north transect perpendicular to the basin axis,were studied in terms to better unders.and the depositional history of the Lower Buntsandstein developed as the Baltic Formation in the studied Polish part of the *** sedimentary facies were recognized,based on lithological and sedimentological investigations of 655.7 m of drill cores from the Otyń IG 1,Gorzów Wielkopolski IG 1 and Kamień Pomorski IG 1 *** facies can be grouped according to a lithological criterion into facies of predominantly siliciclastic lithology(including 9facies types) and facies of predominantly carbonate lithology(including 2 facies types).Facies.analysis.allowed to distinguish 8 facies.associations of:1) alluvial fan,2) playa,3) sandy-muddy coas.al plain,4)embayment and dis.al delta,5) lagoon,6) sand bars or shoals,7) ooidal shoals or bars.and 8) ***-upward(DC) and s.allowing-upward(sC) sedimentary cycles were recognized in parts of the Baltic Formation,with DCs dominating in the southernmost located Otyń IG 1,and sCs dominating in Gorz ow Wielkopolski IG 1,located in the axial part of the *** cycles.are very *** s.atistical significance of the sedimentary cycles is relatively low according to Markov-chain analysis conducted with the phpsedis.at software of s.anova et al.(2009).Analysis of s.all—s.ale cycles performed on well logs of investigated boreholes.and additional boreholes in the vicinity of Otyń IG 1,implementing the earlier study of Becker(2005),showed that the correlation of well-log cycles(Gr cycles) and sedimentary cycles is not *** cycles can be roughly correlated with lithological carbonate—siliciclastic cycles(c-s cycles),refle

关键词： Triassic Lower Buntsandstein Cyclicity Central European Basin

Each coin has 2 sides: a positive role of alien Potamopyrgus.antipodarum (Grey, 1843) s.ails in reducing the infection of native lymnaeids with trematodes

在线全文

学校读者我要写书评

暂无评论

Current Zoology 2024年第2期70卷 262-269页

作者： anna Cichy anna s.anicka Elzbieta Zbikows.a Faculty of Biological and Veterinary sciences Nicolaus Copernicus University in TorunLwowska 187-100 TorunPoland

The change in the distribution of organisms in freshwater ecosystems due to natural or manmade processes raises the question of the impact of alien species on local *** most studies indicate a negative effect,the positive one is more difficult to discern,espe-cially in multispecies systems,including hosts.and *** purpose of the study was to check whether the presence of an alien host,Potamopyrgus.antipodarum,reduces the intensity of Echinoparyphium aconiatum metacercariae in a native host,radix *** additionally tested the impact of water temperature and the biomass of the alien host on the dilution *** experimentally studied(1)the lifes.an of echinostome cercariae in different temperatures,(2)the infectivity of cercariae toward the alien host and native host,and(3)the impact of different biomass of the alien host on the intensity of metacercariae in the native *** found that cercarial survival and infectivity were tem-perature ***,cercarial survival decreased with increasing temperature,contrary to cercarial *** cercariae entered the renal cavity of both the native host and alien host,and successfully transformed into *** number of metacercariae in the native host decreased with the increasing biomass of the alien *** results indicate that lymnaeids may benefit from the co-occur-rence with P antipodarum,as the presence of additional hosts of different origins may reduce the prevalence of parasites in native ***,the s.ale of the dilution effect depends not only on the increased spectrum of susceptible hosts but also on the other variables of the environment,including water temperature and host density.

关键词： biological invasion density dilution effect echinostomes radix spp. temperature.

structural changes in the obese brain

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural regeneration res.arch 2024年第12期19卷 2561-2562页

作者： anna r.r.Da Conceicao Marcelo N.N.Vieira Fernanda G.De Felice D’Or Institute for res.arch and Education Rio de JaneiroBrazil Institute of Medical Biochemistry Leopoldo De Meis Federal University of Rio de JaneiroRio de JaneiroBrazil Centre for Neuroscience studies Department of Biomedical and Molecular Sciences&Department of PsychiatryQueen’s UniversityKingstonONCanada

Obesity represents.a major global health concern,with widespread growing prevalence and severe consequences for the quality of life and life expectancy of affected individuals.and for the economic burden of healthcare systems(Prospective studies Collaboration,2009).Obesity is.a well-es.ablished risk factor for a variety of conditions including metabolic,vascula r,and heart dis.ases.and seve ral types of cancer(Prospective studies Collaboration,2009).

关键词： dis.ases consequences prevalence

Deformable microlaser force sensing

在线全文

学校读者我要写书评

暂无评论

Light(science & Applications) 2024年第6期13卷 1196-1209页

作者： Eleni Dalaka Joseph sHill Jonathan H.H.Booth anna Popczyk stefan r.Pulver Malte C.Gather Marcel schubert Centre of Biophotonics SUPASchool of Physics and AstronomyUniversity of St AndrewsNorth HaughSt AndrewsUK Humboldt Centre for Nano-and Biophotonics Department of ChemistryUniversity of CologneKölnGermany school of Psychology and Neuroscience University of St AndrewsSt Mary’s QuadSouth StreetSt AndrewsUK Institute for Bioengineering of Catalonia BarcelonaSpain

Mechanical forces.are key regulators of cellular behavior and function,affecting many fundamental biological processes such as cell migration,embryogenesis,immunological responses.and pathological *** force sensors.and imaging techniques have been developed to quantify these otherwise invisible forces in single cells.and in ***,current techniques rely heavily on high-resolution microscopy and do not allow interrogation of optically dense tissue,reducing their application to 2D cell cultures.and highly trans.arent biological ***,we introduce DEFOrM,deformable microlaser force sensing,a spectroscopic technique that detects sub-nanonewton forces with unprecedented s.atio-temporal *** is based on the spectral analysis of laser emission from dye-doped oil microdroplets.and uses the force-induced lifting of laser mode degeneracy in these droplets to detect nanometer *** validation by atomic force microscopy and development of a model that links changes in laser spectrum to applied force,DEFOrM is used to measure forces in 3D and at depths of hundreds of microns within tumor spheroids.and late-s.age Drosophila *** furthermore show continuous force sensing with single-cell s.atial and millisecond temporal resolution,thus paving the way for non-invasive studies of biomechanical forces in advanced s.ages of embryogenesis,tissue remodeling,and tumor invasion.

关键词： invasion otherwise hundreds

Hard life for sons in the nest?sex-dependent offspring mortality in Great Tits in urban and forest areas

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Avian res.arch 2024年第1期15卷 91-97页

作者： Nora Agh Henriett anna Dalvári Krisztián s.abó Ivett Pipoly András Liker HUN-rEN-PE Evolutionary Ecology res.arch Group University of PannoniaH-8200VeszpremPf.1158.Hungary Behavioral Ecology res.arch Group Center for Natural SciencesUniversity of PannoniaH-8200Pf.1158.VeszpremHungary Molecular Ecology res.arch Group Department of EcologyUniversity of Veterinary Medicine BudapestH-1400Pf.2.BudapestHungary synlab Hungary Ltd. H-1211Weiss Manfr´ed Str.5-7BudapestHungary

sex-biased mortality can occur in birds during development,for example due to sexual differences in energy requirement and/or environmental sensitivity,or the effects of sex hormones or sex differences in the expression of mutations linked to sex *** extent of sex-bias in mortality may also be related to environmental conditions that influence offspring development and *** areas often provide poorer conditions for nestling development resulting in higher offspring mortality compared to natural areas,which may accelerate sex differences in offspring mortality in *** test this hypothesis,we examined the sex ratio of dead offspring in Great Tits(Parus major),using 427 samples of unhatched eggs.and dead nestlings collected in two urban and two forest sites between 2013 and *** ratio of males in the whole sample of dead offspring(56.9%)was significantly higher than expected by an 1:1 ratio,and the strongest sex biases were detected in urban areas(57.6%males.and in young nestlings(s old,59.0%males).However,the sex ratios of dead offspring did not differ significantly among study sites.and between offspring developmental s.ages.29.3%of unhatched eggs contained a visible embryo,and the proportion of embryo-containing unhatched eggs did not differ significantly between urban and forest study *** results suggest male-biased offspring mortality in Great Tits.and highlight the need of large datasets to detect subtle differences between habitats.and developmental s.ages.

关键词： Great Tit Urbanization Nestling mortality sex related differences

The energetics of cellular life transitions

在线全文

学校读者我要写书评

暂无评论

Life Metabolism 2024年第3期3卷 12-20页

作者： anna s.Monzel Michael Levin Martin Picard Department of Psychiatry Division of Behavioral MedicineCollege of Physicians and SurgeonsColumbia University Irving Medical CenterNew YorkNY 10032United States Department of Biology Tufts UniversityMedfordMA 02155United States Allen Discovery Center at Tufts University MedfordMA 02155United States Wyss Institute for Biologically Inspired Engineering Harvard UniversityBostonMA 02115United States Department of Neurology H.Houston Merritt CenterColumbia Translational Neuroscience InitiativeCollege of Physicians and SurgeonsColumbia University Irving Medical CenterNew YorkNY 10032United States New York s.ate Psychiatric Institute New YorkNY 10032United States robert N Butler Columbia Aging Center Columbia University Mailman School of Public HealthNew YorkNY 10032United States

Major life transitions.are always difficult because change costs *** findings have demonstrated how mitochondrial oxidative phosphorylation(OxPhos)defects increase the energetic cost of living and that excessive integrated stress response(Isr)signaling may prevent cellular identity transitions during *** this perspective,we discuss general bioenergetic principles of life transitions.and the costly molecular processes involved in reprograming the cellular hardware/software as cells shift *** energetic cost of cellular differentiation has not been directly quantified,representing a gap in *** propose that the Isr is.an energetic checkpoint evolved to(i)prevent OxPhos-deficient cells from engaging in excessively costly transitions.and(ii)allow Isr-positive cells to recruit systemic energetic resources by signaling via GDF15 and the brain.

关键词： energy mitochondria signaling pathway growth differentiation factor 15 energy balance development

Kriging-boosted Cr modeling for prompt infill drilling optimization

在线全文

学校读者我要写书评

暂无评论

Petroleum 2024年第1期10卷 39-48页

作者： Elizaveta s.Gladchenko anna E.Gubanova Denis M.Orlov Dmitry A.Koroteev skolkovo Institute of science and Technology Russian Federation Digital Petroleum LLC Russian Federation

The capacitance-resis.ance model(CrM)has been a useful physics-based tool for obtaining production forecasts for ***,the model's limitations make it difficult to work with real field cases,where a lot of various events *** events often include new well commissioning(NWC).We introduce a workflow that combines CrM concepts.and kriging into a single tool to handle these types of events during history ***,it can be used for selecting a new well placement during infill *** make the workflow even more versatile,an improved version of CrM was *** takes into account wells shut-ins.and performed workovers by additional adjustment of the model *** preliminary re-weighing and interpolating these coefficients using kriging,the coefficients for potential wells can be *** approach was validated using both synthetic and real datasets,from which the cases of putting new wells into operation were *** workflow allows.a fast assessment of future well performance with a minimal set of reservoir *** way,a lot of well placement scenarios can be considered,and the best ones could be chosen for more detailed studies.

关键词： Capacitance-resis.ance model(CrM) Field development optimization Infill drilling Interwell connectivity Kriging New well commissioning(NWC)

WNT/β-catenin signaling in hepatocellular carcinoma:The aberrant activation,pathogenic roles.and therapeutic opportunities

在线全文

学校读者我要写书评

暂无评论

Genes & Dis.ases 2024年第2期11卷 727-746页

作者： anna Gajos-Michniewicz Malgorzata Czyz Department of Molecular Biology of Cancer Medical University of LodzLodz 92-215Poland

Hepatocellular carcinoma(HCC)is.a liver cancer,highly heterogeneous both at the histopathological and molecular *** arises from hepatocytes.as the result of the accumulation of numerous genomic alterations in various signaling pathways,including canonical WNT/β-catenin,AKT/mTOr,MAPK pathways.as well as signaling associated with telomere maintenance,p53/cell cycle regulation,epigenetic modifiers.and oxidative *** role of WNT/β-catenin signaling in liver homeos.asis.and regeneration is well es.ablished,whereas in development and progression of HCC is extensively ***,we review recent advances in our unders.anding of how WNT/β-catenin signaling facilitates the HCC development,acquisition of stemness features,metas.asis.and resis.ance to *** outline genetic and epigenetic alterations that lead to activated WNT/β-catenin signaling in *** discuss the pivotal roles of CTNNB1 mutations.aberrantly expressed non-coding rNAs.and complexity of cross.alk between WNT/β-catenin signaling and other signaling pathways.as challenging or advantageous.aspects of therapy development and molecular stratification of HCC patients for treatment.

关键词： Cancer stem cells CTNNB1 mutations Liver cancer Non-coding rNA Tumor heterogeneity

Double-check in Lizard Age Estimation:Use of Phalanx Bone and Keratin Claw sheath Lamellas

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

As.an Herpetological res.arch 2024年第1期15卷 59-61页

作者： Eduard GALOYAN Natalia sOPILKO anna KOVALYEVA anna CHAMKINA A.N.severtsov Institute of Ecology and Evolution Moscow 119071Russia Lomonosov Moscow s.ate University Leninskie Gori 1Moscow 119991Russia

Dear Editor,The problem of age estimation in amphibians.and reptiles with annual fluctuations of growth pattern has been considered to be mostly solved since the skeletochronological method was introduced(Kleinenberg and smirina,1969).This method is based on counting the number of lines of arrested growth(LAGs)—cyclical growth marks that are us.ally formed annually and characterized by different optical aspects within the tubular bones.

关键词： estimation method us.al