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Galápagos land iguana(Conolophus subcristatus)as a seed disperser

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Integrative Zoology 2016年第3期11卷 207-213页

作者： anna TRAVESET manuel NOGALES Pablo VARGAS Beatriz RUmEU Jens m.OLESEN Esporles Mallorca 07190Balearic IslandsSpain Island Ecology and Evolution Research Group(CSIC-IPNA) Instituto de Productos Naturales y Agrobiología38206 TenerifeCanary IslandsSpain Real Jardín Botánico(CSIC-RJB) Department of Biodiversity and ConservationPlaza de Murillo 228014 MadridSpain Centre for Functional Ecology Department of Life SciencesUniversity of CoimbraCalçada Martim de FreitasCoimbra 3000-456Portugal Institute of Bioscience Aarhus UniversityAarhusDenmark and 6Charles Darwin FoundationPuerto AyoraSanta CruzGalápagosQuitoEcuador

The role of the most common land iguana(Conolophus subcristatus)in the Galápagos Islands as an effective seed disperser is explored in this study.A total of 5705 seeds of 32 plant species were identified from 160 scats,4545 of which(80%)appeared visually *** trials of 849 seeds from 29 species revealed that at least 10 species remained viable after passing through the iguana’s gut,although only a small proportion of those seeds(4%)*** any case,we argue that *** exerts an important role on the 7 Galapagos islands where it occurs because of its abundance and capacity to ingest and disperse seeds at long *** results strongly suggest that the Galápagos *** plays an important role as a seed disperser of not only of native species but also some introduced plants in the Galápagos Islands.

关键词： Conolophus subcristatus Fernandina Island Galápagos Islands Saurochory seed dispersal

Using compositional data analysis to explore accumulation of sedentary behavior,physical activity and youth health

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Journal of Sport and Health Science 2022年第2期11卷 234-243页

作者： Simone J.J.m.Verswijveren Karen E.Lamb Josep A.martín-Fernández Elisabeth Winkler Rebecca m.Leech anna Timperio Jo Salmon Robin m.Daly Ester Cerin David W.Dunstan Rohan m.Telford Richard D.Telford Lisa S.Olive Nicola D.Ridgers Institute for Physical Activity and Nutrition School of Exercise and Nutrition SciencesDeakin UniversityGeelongVIC 3216Australia melbourne School of Population and Global Health University of MelbourneParkvilleVIC 3053Australia Department of Computer Science Applied Mathematics and StatisticsUniversity of GironaGirona 17003Spain School of Public Health University of QueenslandHerstonQLD 4006Australia mary macKillop Institute for Health Research Australian Catholic UniversityFitzroyVIC 3065Australia School of Public Health University of Hong KongHong KongChina Baker Heart and Diabetes Institute MelbourneVIC 3004Australia Research Institute for Sport and Exercise University of CanberraBruceACT 2617Australia School of Psychology Deakin UniversityBurwoodVIC 3125Australia ImPACT Research Institute Deakin UniversityBurwoodVIC 3125Australia ANU medical School Australian National UniversityGarranACT 2605Australia

Purpose:The study aimed to describe youth time-use compositions,focusing on time spent in shorter and longer bouts of sedentary behavior and physical activity(PA),and to examine associations of these time-use compositions with cardiometabolic ***:Accelerometer and cardiometabolic biomarker data from 2 Australian studies involving youths 7-13 years old were pooled(complete cases with accelerometry and adiposity marker data,n=782).A 9-component time-use composition was formed using compositional data analysis:time in shorter and longer bouts of sedentary behavior;time in shorter and longer bouts of light-,moderate-,or vigorous-intensity PA;and"other time"(i.e.,non-wear/sleep).Shorter and longer bouts of sedentary time were defined asmin and>5 min,*** bouts of light-,moderate-,and vigorous-intensity PA were defined asmin;longer bouts were defined as≥1 *** models examined associations between overall time-use composition and cardiometabolic ***,associations were derived between ratios of longer activity patterns relative to shorter activity patterns,and of each intensity level relative to the other intensity levels and"other time",and cardiometabolic ***:Confounder-adjusted models showed that the overall time-use composition was associated with adiposity,blood pressure,lipids,and the summary ***,more time in longer bouts of light-intensity PA relative to shorter bouts of light-intensity PA was significantly associated with greater body mass index z-score(zBmI)(β=1.79;SE=0.68)and waist circumference(β=18.35,SE=4.78).When each activity intensity was considered relative to all higher intensities and"other time",more time in light-and vigorous-intensity PA,and less time in sedentary behavior and moderate-intensity PA,were associated with lower waist ***:Accumulating PA,particularly light-intensity PA,in frequent short bursts may be more beneficial for limiting adi

关键词： Accumulation patterns Cardiometabolic health Children Compositional data analysis Time-use

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神经损伤与功能重建 2024年第8期19卷 F0003-F0003页

作者： Adina N macmahon Copas Sarah F mcComish Andreea Petrasca Rachel mcCormack Daniel Ivers anna Stricker Jean m Fletcher maeve A Caldwell 唐颖馨 Discipline of Physiology School of MedicineTrinity Biomedical Sciences InstituteTrinity College DublinDublinIreland Trinity College Institute for Neuroscience Trinity CollegeDublinIreland School of Biochemistry and Immunology Trinity Biomedical Sciences InstituteTrinity College DublinDublinIreland School of medicine Trinity Biomedical Sciences InstituteTrinity College DublinDublinIreland 不详

星形胶质细胞是维持稳态的介质,但在帕金森病(Parkinson’s disease,PD)中参与神经炎症。越来越多的证据表明外周免疫细胞参与了PD的发病机制。因此,本研究旨在确定外周免疫细胞分泌的细胞因子在调节中脑星形胶质细胞反应性中的潜在作... 详细信息

星形胶质细胞是维持稳态的介质,但在帕金森病(Parkinson’s disease,PD)中参与神经炎症。越来越多的证据表明外周免疫细胞参与了PD的发病机制。因此,本研究旨在确定外周免疫细胞分泌的细胞因子在调节中脑星形胶质细胞反应性中的潜在作用。人类诱导性多能干细胞(iPSC)衍生的中脑星形胶质细胞暴露于5%和10%的CD4^(+)T细胞条件培养基(CD4Cm)24小时、72小时和7天,以评估长期暴露的影响。此外,星形胶质细胞还暴露于Th17细胞细胞因子IL-17A(10 ng/mL),单独或与TNF-α(0.3 ng/mL)结合,在24小时、72小时和7天评估2种细胞因子可能的协同效应。CD4Cm在中脑星形胶质细胞中引起了急性及长期的变化。观察到了NFκB向细胞核的转移增加,以及在24小时时促炎基因IL-1β和CXCL10的表达增加;在24小时和48小时时C3、LCN2和IL-6的表达增加;同时在这些时间点促炎细胞因子IL-6和CXCL10的释放也有所增加。IL-17A和TNF-α的组合对增加促炎基因表达和细胞因子释放产生了协同效应。IL-17A和TNF-α在24小时时增加了S100β的强度,在72小时时减少了细胞核面积并增加了星形胶质细胞的圆度。在72小时时观察到了γH2AX强度的协同效应,并且在7天时观察到了乳酸脱氢酶(LDH)释放的增加。我们的结果表明,IL-17A和TNF-α协同作用,增强了中脑星形胶质细胞的反应性,其程度类似于CD4Cm。这突出了外周免疫细胞分泌的细胞因子在增强中脑星形胶质细胞反应状态方面的重要性,并提示了它们在PD发病机制中的可能作用。

关键词：帕金森病星形胶质细胞细胞因子诱导性多能干细胞神经炎症反应性星形胶质细胞

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Trihalomethane concentrations in tap water as determinant of bottled water use in the city of Barcelona

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Journal of Environmental Sciences 2017年第8期29卷 77-92页

作者： Laia Font-Ribera Jordi Colomer Cotta anna Gómez-Gutiérrez Cristina m.Villanueva ISGlobal Centre for Research in Environmental Epidemiology (CREAL) 08003 Barcelona Spain ImIm (Hospital del mar medical Research Institute) 08003 Barcelona Spain Uniuersitat Pompeu Fabra (UPF) 08003 Barcelona Spain CIBER Epidemiologfa y Salud Publica (CIBERESP) 28029 Madrid Spain Public Health Agency of Barcelona (ASPB) 08023 Barcelona Spain

Bottled water consumption is increasing worldwide, despite its huge economic and environmental cost. We aim to describe personal and tap water quality determinants of bottled water use in the city of Barcelona. This cross-sectional study used data from the Health Survey of Barcelona in 2006（N = 5417 adults）. The use of bottled water to drink and to cook was evaluated in relation to age, gender, educational level, district and levels of trihalomethanes（THms）, free chlorine, conductivity, chloride, sodium, p H, nitrate and aluminium in municipal tap water using Robust Poisson Regression. The prevalence of bottled water use to drink and cook was 53.9% and 6.7%, respectively. Chemical parameters in water had a large variability（interquartile range of THms concentrations： 83.2–200.8 μg/L）and were correlated between them, except aluminium. Drinking bottled water increased with educational level, while cooking with bottled water was higher among men than among women and decreased with age. After adjusting by these personal determinants, a dose–response relationship was found between concentrations of all chemicals except aluminium in tap water and bottled water use. The highest association was found for THms,with a Prevalence Ratio of 2.00（95%CI = 1.86, 2.15） for drinking bottled water and 2.80（95%CI = 1.72, 4.58） for cooking with bottled water, among those with 〉 150 μg/L vs. 〈 100 μg/L THms in tap water. Conclusion： more than half of Barcelona residents regularly drank bottled water, and the main determinant was the chemical composition of tap water,particularly THm level.

关键词： Tap water Drinking water Trihalomethanes Organoleptics Determinants Prevalence

Catalyzing Singlet Fission by Transition metals:Second versus Third Row Effects

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Precision Chemistry 2023年第9期1卷 555-564页

作者： Yuxuan Hou Ilias Papadopoulos Yifan Bo anna-Sophie Wollny michael J.Ferguson Lukas A.mai Rik R.Tykwinski Dirk m.Guldi Department of Chemistry University of AlbertaEdmontonAlberta T6G 2G2Canada Department of Chemistry and Pharmacy&Interdisciplinary Center for molecular materials(ICmm) Friedrich-Alexander-University Erlangen-Nuremberg91058 ErlangenGermany Department of Applied Chemistry Graduate School of EngineeringCenter for Molecular Systems(CMS)Kyushu University744 Moto-okaNishi-kuFukuoka 819-0395Japan

The synthesis and characterization of platinum(II)and palladium(II)complexes bearing two(dimers Pt(L_(pc))_(2)Cl_(2)and Pd(L_(pc))_(2)Cl_(2)),one(monomers Pt(L_(pc))(L_(ref))Cl_(2)and Pd(L_(pc))(L_(ref))-Cl_(2)),or no(reference compounds Pt(L_(ref))_(2)Cl_(2)and Pd(L_(ref))_(2)Cl_(2))pentacene-based pyridyl ligands are *** properties of the dimers are probed by means of steady-state and time-resolved transient absorption measurements in compar-ison to the monomer and model *** results document that despite enhanced spin−orbit coupling from the presence of heavy atoms,intramolecular singlet fission(iSF)is not challenged by intersystem *** thus yields correlated triplet pairs and even uncorrelated triplet excited states upon ***,significant separation of the two pentacenyl groups facilitates decoupling of the two ***,the mechanism of iSF is altered depending on the respective metal center,that is,Pt(II)versus Pd(II).The dimer based on Pt(II),Pt(L_(pc))2Cl_(2),exhibits a direct pathway for the iSF and forms a correlated triplet pair with singlet−quintet spin-mixing within 10 ns in variable *** the other hand,the dimer based on Pd(II),Pd(L_(pc))_(2)Cl_(2),leads to charge transfer mixing during the population of the correlated triplet pair that is dependent on solvent ***,Pd(L_(pc))_(2)Cl_(2)gives rise to a stable equilibrium between singlet and quintet correlated triplet pairs with lifetimes of up to 170 *** differences in the size and polarizability,when contrasting platinum(II)with palladium(II),are the most likely rationale for the underlying trends.

关键词： metal complexes singlet fission pentacene dimers ultrafast spectroscopy electronic coupling

Reduced formation of peroxide and radical species stabilises iron-based hybrid catalysts in polymer electrolyte membrane fuel cells

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Journal of Energy Chemistry 2022年第2期31卷 433-438页

作者： Dongyoon Shin Sabita Bhandari marc FTesch Shannon ABonke Frédéric Jaouen Sonia Chabbra Christoph Pratsch Alexander Schnegg anna K.mechler max Planck Institute for Chemical Energy Conversion Stiftstr.34–3645470 Mülheim an der RuhrGermany ICGm Univ.MontpellierCNRSENSCMMontpellierFrance Fritz Haber Institute of the max Planck Society Department of Inorganic ChemistryFaradayweg 4-614195 BerlinGermany

The incorporation of Pt into an iron-nitrogen-carbon(Fe NC)catalyst for the oxygen reduction reaction(ORR)was recently shown to enhance catalyst stability without Pt directly contributing to the ORR ***,the mechanistic origin of this stabilisation remained *** is established herein with rotating ring disc experiments that the side product,H_(2)O_(2),which is known to damage FeNC catalysts,is suppressed by the presence of *** formation of reactive oxygen species is additionally inhibited,independent of intrinsic H_(2)O_(2) formation,as determined by electron paramagnetic *** electron microscopy identifies an oxidised Fe-rich layer covering the Pt particles,thus explaining the inactivity of the latter towards the *** insights develop understanding of Fe NC degradation mechanisms during ORR catalysis,and crucially establish the required properties of a precious metal free protective catalyst to improve Fe NC stability in acidic media.

关键词： Electrochemistry Fuel cells Oxygen reduction reaction Non-precious metal catalyst Hybrid catalyst Stability

Stabilization and visual analysis of video-recorded sailing sessions

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Visual Computing for Industry,Biomedicine,and Art 2021年第1期4卷 258-267页

作者： Gijs m.W.Reichert marcos Pieras Ricardo marroquim anna Vilanova Computer Graphics and Visualization Technical University DelftDelft 2628CDThe Netherlands Visualization Group Technical University EindhovenEindhovenAZ 5612The Netherlands

One common way to aid coaching and seek to improve athletes’performance is by recording training sessions for posterior *** the case of sailing,coaches record videos from another boat,but usually rely on handheld devices,which may lead to issues with the footage and missing important *** the other hand,by autonomously recording the entire session with a fixed camera,the analysis becomes challenging owing to the length of the video and possible stabilization *** this work,we aim to facilitate the analysis of such full-session videos by automatically extracting maneuvers and providing a visualization framework to readily locate interesting ***,we address issues related to image ***,an evaluation of the framework points to the benefits of video stabilization in this scenario and an appropriate accuracy of the maneuver detection method.

关键词： Visualization Sports Visual-analytics

Transplanted kidney loss during colorectal cancer chemotherapy:A case report

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World Journal of Clinical Cases 2022年第19期10卷 6647-6655页

作者： marta Pośpiech Aureliusz Kolonko Teresa Nieszporek Sylwia Kozak anna Kozaczka Henryk Karkoszka mateusz Winder Jerzy Chudek Department of Internal Diseases and Oncological Chemotherapy Medical University of Silesia in KatowiceKatowice 40-027Poland Department of Nephrology Transplantation and Internal MedicineMedical University of Silesia in KatowiceKatowice 40-027Poland Department of Nephrology Transplantation and Internal MedicineMielecki Clinical Hospital of the Medical University of SilesiaKatowice 40-027Poland Department of Internal Diseases and Oncological Chemotherapy Mielecki Clinical HospitalKatowice 40-027Poland Department of Radiology and Nuclear medicine Medical University of Silesia in KatowiceKatowice 40-752Poland

BACKGROUND The overall risk of de novo malignancies in kidney transplant recipients(KTRs)is higher than that in the general *** is associated with long-lasting exposure to immunosuppressive agents and impaired oncological vigilance due to chronic kidney *** cancer(CRC),frequently diagnosed in an advanced stage,is one of the most common malignancies in this cohort and is associated with poor ***,because of the scarcity of data concerning adjuvant chemotherapy in this group,there are no clear guidelines for the specific management of the CRCs in *** present a patient who lost her transplanted kidney shortly after initiation of adjuvant chemotherapy for colon *** SUmmARY A 36-year-old woman with a medical history of kidney transplantation(2005)because of end-stage kidney disease,secondary to chronic glomerular nephritis,and long-term immunosuppression was diagnosed with locally advanced pT_(4A)N_(1B) m_(0)(clinical stage Ⅲ)colon adenocarcinoma *** right hemicolectomy,the patient was qualified to receive adjuvant chemotherapy that consisted of oxaliplatin,leucovorin and 5-fluorouracil(FOLFOX-4).The deterioration of kidney graft function after two cycles caused chemotherapy cessation and initiation ofhemodialysis therapy after a few months. Shortly after that, the patient started palliativechemotherapy because of cancer recurrence with intraperitoneal *** of adjuvant chemotherapy for colon cancer increases the risk of rapid kidney graft lossdriven also by under-immunosuppression。

关键词： Kidney transplantation Colorectal cancer Adjuvant chemotherapy Graft loss Complications Case report

Crystal structure and thermal expansion of perovskites containing uranium(VI) and rare-earth elements

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Journal of Rare Earths 2009年第1期27卷 4-11页

作者： Aleksandr Knyazev anna Ershova Nikolai Chernorukov Nizhny Novgorod State University

By the method of high-temperature reactions in solid phase, compounds with the general formula mⅡ（AⅢ2/3U1/3）O3（mⅡ=Sr, AⅢ=Sc, In;mⅡ=Ba, AⅢ=Sc, In, Y, Nd-Lu） were *** structures（space groups Fm 3 m and Pnma） were refined by the Rietveld method and morphotropic transition in Ba（Ln2/3U1/3）O3 on the border of Gd-Tb was *** means of high-temperature X-ray diffraction, phase transitions were studied and thermal expansion coefficients were determined.

关键词： perovskite uranium X-ray diffraction Rietveld structure thermal expansion rare earths