检索结果-南通市图书馆

Monitoring hepatitis C virus treatment rates in an Opioid Treatment Program:A longitudinal study

World Journal of Gastroenterology 2020年第38期26卷 5874-5883页

作者： Arantza Sanvisens Inmaculada Rivas Eva Faure Néstor Espinach anna hernandez-rubio Xavier Majó Joan Colom Robert Muga Department of Internal Medicine Hospital Universitari Germans Trias i PujolBadalona 08916Spain Mental Health and Addiction Service Badalona Serveis Assistencials-BSABadalona 08911Spain Department of Internal Medicine Hospital Universitari Germans Trias i PujolUniversitat Autònoma de BarcelonaBadalona 08916Spain Program on HIV STIs and Viral Hepatitis-PCAVIHV Public Health Agency of CataloniaGeneralitat de CatalunyaBarcelona 08005Spain

BACKGROUND Direct-acting antivirals(DAAs)are recommended for the treatment of hepatitis C virus(HCV)infection in patients treated with methadone or *** To assess HCV treatment rates in an Opioid Treatment Program(OTP).METHODS This longitudinal study included 501 patients(81.4%men,median age:45 years;interquartile range:39-50 years)enrolled in an OTP between October 2015 and September *** were followed until September *** on sociodemographics,substance use,HCV infection,human immunodeficiency virus(HIV)infection and laboratory parameters were collected at *** analyzed medical records to evaluate HCV ***-Meier methods and Cox regression models were used to analyze the DAA treatment uptake and to identify treatment *** Prevalence of HCV and HIV infection was 70%and 34%,*** anti-HCV-positive(n=336)patients,47.2%,41.3%,and 31.9%used alcohol,cannabis,and cocaine,***-RNA tests were positive in 233(69.3%)*** patients(8.3%)cleared the infection,and 59/308(19.1%)had received interferon-based treatment regimens before *** 249 patients eligible,111(44.6%)received *** rates significantly increased over time from 7.8/100 person-years(p-y)(95%CI:5.0-12.3)in 2015 to 18.9/100 p-y(95%CI:11.7-30.3)in *** a multivariate analysis,patients with HIV co-infection were twice as likely to receive DAAs(HR=1.94,95%CI:1.21-3.12)than patients with HCV *** drug use was an independent risk factor for not receiving treatment against infection(HR=0.48,95%CI:0.29-0.80).CONCLUSION HCV treatment is evolving in patients with HCV-HIV *** drug use while in an OTP might negatively impact the readiness to treat infection.

关键词： Direct-acting antiviral agents Opioid Treatment Program Opioid agonist therapy Hepatitis C virus infection Human immunodeficiency virus infection Drug use

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

引用

Current Zoology 2020年第5期66卷 493-503页

作者： Francesc rubio-Gracia Emili Garcia-Berthou Helena Guasch Lluis Zamora anna Vila-Gispert Institute of Aquatic Ecology University of Girona17003 GironaSpain Integrative Freshwater Ecology Group Centre d'Tstudis Avanqats de BlanesCSIC17300 BlanesSpain

Energy metabolism fuels swimming and other biological *** compared the swimming performance and energy metabolism within and across eight freshwater fish *** swim tunnel respirometers,we measured the standard metabolic rate(SMR)and maximum metabolic rate(MMR)and calculated the critical swimming speed(Ucrit).We accounted for body size,metabolic traits,and some morphometric ratios in an effort to understand the extent and underlying causes of *** mass was largely the best predictor of swimming capacity and metabolic traits within ***,we found that predictive models using total length or SMR,in addition to body mass,signicantly in creased the explained variation of Ucrit and MMR in certain fish *** predictive models also underlined that,once body mass has been accounted for,Ucrit can be independently affected by total length or *** study exemplifies the utility of multiple regression models to assess within-species *** interspecific level,our results showed that variation in UcriX can partly be explained by the variation in the interrelated traits of MMR,finen ess,and muscle *** the species studied,bleak Al burn us alburnus performed best in terms of swimming performance and *** contrast,pumpkinseed Lepomis gibbosus showed very poor swimming performance,but attained lower mass-specific cost of transport(MCOT)than some rheophilic species,possibly reflecting a cost reduction strategy to compensate for hydrod yn amic *** con elusion,this study provides insight into the key factors in fluenci ng the swimming performa nee of fish at both intra-and in terspecific levels.

关键词： body size maximal metabolic rate morphology swimming efficiency

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

引用

Health 2020年第10期12卷 1360-1370页

作者： Lucas Lima de Carvalho Lucas Rodrigues Claro Amanda dos Santos Cabral Marcela Pereira da Silva Mello Bruna Liane Passos Lucas Marcelly Valadares Souza Simone Fonseca Lucas Alexandre Oliveira Tellles Ravini Fernandez dos Santos Vieira dos Santos Marcia Augusta Pereira dos Santos Claudia Lima Campos Alzuguir Maria Cristina Dias da Silva Antonio Eduardo Vieira dos Santos Maria Antonieta rubio Tyrrell Eduardo Alexander Júlio César Fonseca Lucas anna Nery School of Nursing Federal University of Rio de Janeiro Rio de Janeiro Brazil Celso Lisboa University Center Rio de Janeiro Brazil State Secretariat of Education of Rio de Janeiro Rio de Janeiro Brazil Department of Medicine in Primary Health Care Faculty of Medicine Federal University of Rio de Janeiro Rio de Janeiro Brazil Department of Maternal and Child Nursing Faculty of Nursing State University of Rio de Janeiro Rio de Janeiro Brazil Department of Maternal-Child Nursing Faculty of Nursing Fernandez Figueira Institute of the Oswaldo Cruz Foundation State University of Rio de Janeiro Rio de Janeiro Brazil

This documentary research aimed to describe the results of an epidemiological survey that sought to determine the prevalence of Infections Related to Health Care (IRHC) in newborns admitted to a Neonatal Intensive Care Unit (NICU) at the city of Rio de Janeiro. For methodology, the existing data in the original research database were used as the primary source. The method used was the case study in a quantitative approach. The data have been statistically arranged by odds ratio, which measured the possibility of IRHC development at the 102 newborns, by exposition at the risk factors. Results: IRHC prevalence with pneumonias, sepsis, navel’s infection and ocular infections predominance rises. Prematures are 4.10 more susceptible. Twelve hours after amniotic rupture there are 1.77 more chances of infections. Babies with more than 10 days of hospitalization are 4.70 more susceptible than those with 10 days. The registers examined were incipient at the IRHC’s characterization, beginning and duration, which make the IRHC’s diagnostic/notification difficult.

关键词： Neonatal Nursing Cross Infection Data Interpretation Statistical

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：