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Research on a New Type of Diamond Saw Plate

厦门大学学报（自然科学版） 2002年第S1期41卷 294-295页

作者： SHI Xiao-liang, DUAN Long-chen, TANG Feng-lin, YANG Kai- hua (Engineering Faculty, China University of Geosciences, Wuhan 430074, Ch ina)

With the developing of stone material, diamond saw pl ate is used widely, and in order to increase cutting efficiency and life-span o f diamond saw plate, there are a lot of research jobs of segment for diamond saw plate. Layered segment for diamond saw plate is to divide single segment into s everal cutting tools by its structure, then increases rock-cutting faces. For i mpregnated man-made diamond saw plate, the bonding strength of diamonds with ma trix material has great effect on its life and service. Diamond is a kind of non metal and there is such high interface energy between diamond and common metals or alloys that diamond surface can’t be soaked by low melt-point metal or allo y. Diamonds are hold in metal matrix of working layer only mechanically, rather than bonded chemically, so the usage rate of diamonds in working layer is very l ow. Weakly impregnated method refers to covering diamonds with a thin layer of tu ngsten carbide mechanically by physical method, and chemical plating membrane re fers to coating a layer of carbide, which can react with the carbon atoms on the surface of diamond by chemical method and be soaked by matrix metal. In this pa per it analyses working mechanism and sintering process of layered segment of di amond saw plate by means of resistor hot-pressing sintering, it points out shor tages of layered structure, and raises using weakly impregnated layer instead of pure matrix layer, then overcomes the pure matrix layer slipping by pulling out diamonds earlier to improve cutting efficiency of saw plate, in the same time u ses diamond grains of chemical plating membrane proposed then preventing the hea t-hurting to diamond grains in working layer during the process of welding and sintering and improving the bonding strength of diamond with matrix, then improv ing life-span and aging of diamond saw. The theory of the design of mixed holding of diamonds by matrix of saw plate assures that chemical plating diamonds in working layer cut

关键词： diamond saw plate layered segment weakly impre gnated plating membrane slipping

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Expression of matrix metalloproteinase-11 is increased under conditions of insulin resistance

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World Journal of Diabetes 2017年第9期8卷 422-428页

作者： Biagio Arcidiacono Eusebio Chiefari anna Elisa Laria Sebastiano Messineo Francesco Luciano Bilotta Domenico Britti Daniela Patrizia Foti anna Foryst-Ludwig Ulrich Kintscher Antonio Brunetti Department of Health Sciences University"Magna Gr█cia"of Catanzaro Institute of Phar-macology Center for Cardiovascular Research

AIM To investigate matrix metalloproteinase-11(MMP-11) expression in adipose tissue dysfunction, using in vitro and in vivo models of insulin *** Culture of mouse 3T3-L1 preadipocytes were induced to differentiation into mature 3T3-L1 adipocytes. Cellular insulin resistance was induced by treating differentiated cultured adipocytes with hypoxia and/or tumor necrosis factor(TNF)-α, and transcriptional changes were analyzed in each condition thereafter. For the in vivo studies, MMP-11 expression levels were measured in white adipose tissue(WAT) from C57BL/6J mice that underwent low fat diet or high-fat feeding in order to induce obesity and obesity-related insulin resistance. Statistical analysis was carried out with GraphP ad Prism *** MMP-11 m RNA expression levels were significantly higher in insulin resistant 3T3-L1 adipocytes compared to control cells(1.46±0.49vs0.83±0.21, respectively;P<0.00036). The increase in MMP-11 expression was observed even in the presence of TNF-α alone(3.79±1.11vs1±0.17, P<0.01) or hypoxia alone(1.79±0.7vs0.88±0.1, P<0.00023). The results obtained in in vitro experiments were confirmed in the in vivo model of insulin resistance. In particular, MMP-11 m RNA was upregulated in WAT from obese mice compared to lean mice(5.5±2.8vs1.1±0.7, respectively; P<3.72E-08). The increase in MMP-11 levels in obese mice was accompanied by the increase in typical markers of fibrosis, such as collagen type Ⅵ alpha 3(Col6_α3), and fibroblast-specific protein *** Our results indicate that dysregulation of MMP-11 expression is an early process in the adipose tissue dysfunction, which leads to obesity and obesity-related insulin resistance.

关键词： Metalloproteinase-11 Insulin resistance Type 2 diabetes Fibrosis Hypoxia Tumor necrosis factor-α Inflammation

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A fermented rapeseed meal additive:Effects on production performance,nutrient digestibility,colostrum immunoglobulin content and microbial flora in sows

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Animal Nutrition 2019年第4期5卷 373-379页

作者： Eugeniusz R.Grela anna Czech Martyna Kiesz Lukasz Wlazlo Bozena Nowakowicz-Debek Institute of Animal Nutrition and Bromatology University of Life Sciences in LublinLublin20-950Poland Department of Biochemistry and Toxicology Faculty of BiologyAnimal Sciences and BioeconomyUniversity of Life Sciences in LublinLublin20-950Poland Department of Animal Hygiene and Environment Faculty of Biology and Animal BreedingUniversity of Life Sciences in LublinLublin20-950Poland

This study was to assess the effect of fermented rapeseed meal(FRSM) in the diet of sows,taking into account the physiological period(pregnancy or lactation) and reproductive cycle(primiparous or multiparous sows),on production performance,nutrient digestibility,colostrum immunoglobulin content,and microbial flora in *** experimental material included 30 primiparous gilts and 30 multiparous sows after their second *** animals in the control groups C_G(gilts) and Cs(sows)received a standard diet for pregnant or lactating sows,depending on the reproductive *** groups E_G and E_S comprised gilts and multiparous sows,respectively,receiving a diet with a 4%share of FRSM in place of soybean meal up to 100 d of *** addition,from 100 d of gestation to7 d of lactation,the sows in experimental groups received a diet with a 9% share of FRSM,and then again a diet with a 4% share of FRSM until the end of *** addition of 4% to 9% share of a FRSM component in feed significantly improves production parameters,mainly in primiparous gilts,leading to an increase in litter size and in litter weight at 28 d of *** also helps to improve the digestibility of crude protein,fat,and crude fiber,and positively affects the gut microbiota of *** of rapeseed meal is an effective way to reduce anti-nutrients and to increase the level of lactic acid in the diet It also stimulates the immune system,which improves piglet health,reducing the severity of diarrhoea and mortality.

关键词： Fermented rapeseed meal Sows Microbiota Digestibility Colostrum

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Inhibiting WNT secretion reduces high bone mass caused by Sost loss-of-function or gain-of-function mutations in Lrp5

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骨研究:英文版 2023年第3期11卷 595-606页

作者： Cassandra R.Diegel ina Kramer Charles Moes Gabrielle E.Foxa Mitchell J.McDonald Zachary B.Madaj Sabine Guth Jun Liu Jennifer L.Harris Michaela Kneissel Bart O.Williams Department of Cell Biology Van Andel Institute333 Bostwick Ave.NEGrand RapidsMI 49503USA Diseases of Aging and Regenerative Medicine Novartis Institutes for Biomedical ResearchCH-4002 BaselSwitzerland Bioinformatics and Biostatistics Core Van Andel Institute333 Bostwick Ave.NEGrand RapidsMI 49503USA Oncology Novartis Institutes for Biomedical ResearchSan DiegoCA 92121USA

Proper regulation of Wnt signaling is critical for normal bone development and *** in several Wnt signaling components,which increase the activity of the pathway in the skeleton,cause high bone mass in human subjects and mouse *** bone mass is often accompanied by severe headaches from increased intracranial pressure,which can lead to fatality and loss of vision or hearing due to the entrapment of cranial *** addition,progressive forehead bossing and mandibular overgrowth occur in almost all *** that would provide symptomatic relief in these subjects are ***-mediated palmitoylation is necessary for Wnt secretion and binding to the frizzled *** inhibition of porcupine is a highly selective method of Wnt signaling *** treated three different mouse models of high bone mass caused by aberrant Wnt signaling,including homozygosity for loss-of-function in Sost,which models sclerosteosis,and two strains of mice carrying different point mutations in Lrp5(equivalent to human G171V and A214V),at 3 months of age with porcupine inhibitors for 5–6 *** significantly reduced both trabecular and cortical bone mass in all three *** demonstrates that porcupine inhibition is potentially therapeutic for symptomatic relief in subjects who suffer from these disorders and further establishes that the continued production of Wnts is necessary for sustaining high bone mass in these models.

关键词： homeostasis function mass

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Effects of protein and mineral supplementation on the performance of lactating dairy cows gobra and crossbreed guzerat during the dry season in senegal

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Open Journal of Animal Sciences 2014年第1期4卷 18-22页

作者： fat Cheikh Ndione Emile Codjo Agbangba Ousmane Ndiaye Idrissa Sane Abdou Diouf Amadou Tamsir Diop Centre de Recherches Zootechniques de Dahra Institut Sénégalais de Recherches Agricoles Dahra Sénégal Département de Biologie Végétale Université Cheikh Anta Diop Dakar Sénégal Laboratoire national D’élevage et de Recherche Vétérinaire (LNERV) Institut Sénégalais de Recherches Agricoles Dakar Sénégal

The purpose of this study carried out in the township of Dahra was to access the effect of dry season protein and mineral supplementation of Gobra and Crossbreed Guzerat cows on milk production. The experimental design is a completely randomized block. The treatments were: supplement of molasse-urea blocks with supplement of hay;supplement of molasse-urea blocks without any hay;no supplement of molasse-urea blocks and supplement of hay;no supplement of molasse-urea block without any hay. For each breed, the treatments were replicated three times on a lot of cows with the similar zootechnic parameters. A total of twelve lactating cows per breed were then used. The supplement of block + hay has significantly (p < 5%) allowed obtaining the largest average daily quantity of milk: 1.9 ± 0.7L/day/cow and 2.4 ± 0.8 L/day/cow respectively in Gobra and Crossbreed Gobra*Guzerat. The increases in production compared to the control treatment (without supplement) are 52.63% and 100% respectively in the breed Gobra and Gobra*Guzerat. The supplement of hay comes in the second place and contributes to an additional production of 66.66% in both breeds of cow. Then, the supplement of block follows and it allows increasing the production of 44.44% and 50% respectively in Gobra and Crossbreed. In both races, the supplement of block + hay has allowed obtaining the highest profits of $1.6/L/day/cow for Gobra and $ 2.8/L/day/cow for the Crossbreed, that equals to an increase by $ 0.3 and $ 0.9 compared to the control treatment. The supplement of hay and the block supplement have respectively given a profit of 0.4 and $ 0.3/L/day/cow in Gobra and 0.6 and $ 0.4/L/day/cow in the Crossbreed. The adoption of supplementation molasse-urea block + hay by producers appears an alternative to boost milk production in dry season.

关键词： Milk Yield Supplements Gobra Guzerat Dry Season

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神阙穴隔盐灸治疗儿童遗尿的临床观察

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针灸临床杂志 2007年第8期23卷 55-56页

作者：林桂君 fatǘ Camará 成都市温江区人民医院四川成都611130 几内亚比绍圣门德斯国家医院

目的:观察神阙穴隔盐灸合并针灸对非洲儿童遗尿的疗效。方法:将70例遗尿患儿随机分为治疗组(38例);对照组(32例),分别进行神阙穴隔盐灸合并针灸和针刺治疗。按《中医病症诊断疗效标准》中判效标准评定疗效。结果:神阙穴隔盐灸合并针灸... 详细信息

目的:观察神阙穴隔盐灸合并针灸对非洲儿童遗尿的疗效。方法:将70例遗尿患儿随机分为治疗组(38例);对照组(32例),分别进行神阙穴隔盐灸合并针灸和针刺治疗。按《中医病症诊断疗效标准》中判效标准评定疗效。结果:神阙穴隔盐灸合并针灸组患儿痊愈平均治疗次数与对照组差异有统计学意义,结论:神阙穴隔盐灸合并针灸对改善非洲儿童遗尿有明显作用,机制需进一步探讨。

关键词：儿童遗尿神阙穴隔盐灸针灸治疗随机对照

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Effects of liraglutide on metabolic syndrome in WBN/Kob diabetic fatty rats supplemented with a high-fat diet

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Animal Models and Experimental Medicine 2020年第1期3卷 62-68页

作者： Noriyuki Kaji Yoshiichi Takagi Satomi Matsuda anna Takahashi Sakurako Fujio Fumitoshi Asai Laboratory of Veterinary Pharmacology School of Veterinary MedicineAzabu UniversityKanagawaJapan

Background:Liraglutide,a GLP-1 receptor agonist,has recently been used to treat metabolic syndrome(MS)because of its anti-diabetic and anti-obesity *** have previously shown that Wistar Bonn Kobori diabetic and fatty(WBN/Kob-Leprfa,WBKDF)rats fed a high-fat diet(HFD)developed MS including marked obesity,hyperglycemia,and *** obtain further information on WBKDF-HFD rats as a severe MS model,we performed a pharmacological investigation into the anti-MS effects of liraglutide in this ***:Seven-week-old male WBKDF-HFD rats were allocated to three groups(n=8 in each group):a vehicle group,a low-dose liraglutide group,and a high-dose liraglutide *** received subcutaneous injections of either saline or liraglutide at doses of 75 or 300μg/kg body weight once daily for 4 ***:Results showed that liraglutide treatment reduced body weight gain and food intake in a dose-dependent *** marked hyperglycemia and the glucose tolerance were also significantly ameliorated in the liraglutide-treated ***,liraglutide also reduced the plasma triglyceride concentration and liver fat ***:The present study demonstrated that liraglutide could significantly alleviate MS in WBKDF-HFD rats,and the reaction to liraglutide is similar to human patients with ***-HFD rats are therefore considered to be a useful model for research on severe human MS.

关键词： diabetes mellitus liraglutide metabolic syndrome models animal obesity

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Body weight, lifestyle, dietary habits and gastroesophageal reflux disease

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World Journal of Gastroenterology 2009年第14期15卷 1690-1701页

作者： Davide Festi Eleonora Scaioli Fabio Baldi Amanda Vestito Francesca Pasqui anna Rita Di Biase Antonio Colecchia Department of Clinical Medicine University of Bologna Bologna Department of Pediatrics University of Modena Modena Italy

While lifestyle modifications are currently used as firstline treatment for subjects with gastroesophageal reflux disease (GERD), the pathogenetic role of lifestyle factors and consequently, the efficacy of lifestyle measures is controversial. Our aim was to systematically review the pathogenetic link between overweight/ obesity, dietary habits, physical activity and GERD, and the beneficial effect of specific recommended changes, by means of the available literature from the 1999 to the present. Obesity, in particular, abdominal obesity, plays a key role in determining GERD symptoms and complications through mechanical and metabolic effects. Controlled weight loss (by diet or surgery) is effective in improving GERD symptoms. No definitive data exist regarding the role of diet and, in particular, of specific foods or drinks, in influencing GERD clinical manifestations. Moderate physical activity seems to be beneficial for GERD, while vigorous activity may be dangerous in predisposed individuals. In conclusion, being obese/overweight and GERD-specific symptoms and endoscopic features are related, and weight loss significantly improves GERD clinical-endoscopic manifestations. The role of dietary behavior, mainly in terms of specific dietary components, remains controversial. Mild routine physical activity in association with diet modifications, i.e. a diet rich in fiber and low in fat, is advisable in preventing reflux symptoms.

关键词： Food intake Food questionnaire Heartburn Obesity Physical activity

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钨的世界需求与供应

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中国钨业 1994年第7期9卷 1-7页

作者： fat-Chun Leung Ki 罗英浩联合国贸易与发展会议

第六次国际钨讨论会结束后,我刊从今年第2期开始陆续刊出11篇论文,为使会议论文尽快与读者见面,现将余下的7篇在本期和下期全部刊出。在编辑过程中,得到论文作者、译者和中国有色金属学会有关同志的大力支持和协作,在此特表示诚挚的谢... 详细信息

第六次国际钨讨论会结束后,我刊从今年第2期开始陆续刊出11篇论文,为使会议论文尽快与读者见面,现将余下的7篇在本期和下期全部刊出。在编辑过程中,得到论文作者、译者和中国有色金属学会有关同志的大力支持和协作,在此特表示诚挚的谢意。我们拟在近期将会议论文集中成专集出版,欢迎订阅。

关键词：会议论文集编辑过程金属制品钨矿石消费国家经济改革设备部门钨市场中间产品市场经济国家

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面向海外华人的广府文化传播分析 ——以广东广播电视台为例

面向海外华人的广府文化传播分析 ——以广东广播电视台为例

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作者：谢马驹（TSE ONE fat Mathieu）广东外语外贸大学

学位级别：硕士

本文以广东电视台国际频道面向海外华人的广府文化传播为研究对象,旨在回答以下的问题:广东广播电视台国际频道传播其内容过程中对海外华人产生什么影响?本研究以传播学经典理论拉斯韦尔5W模式为理论框架,分析笔者从2018年6月到11月在... 详细信息

本文以广东电视台国际频道面向海外华人的广府文化传播为研究对象,旨在回答以下的问题:广东广播电视台国际频道传播其内容过程中对海外华人产生什么影响?本研究以传播学经典理论拉斯韦尔5W模式为理论框架,分析笔者从2018年6月到11月在广东电视台国际频道以实习生身份调查采集和观察到的数据。研究结果表明,广东广播电视台国际频道面向海外华人传播广府文化的节目以《今日广东》和《小马大哈》为代表,通过传统媒体和社交新媒体相结合的方式进行传播,报导广府传统节庆、广府美食和广东社会热点的题材最受关注。

关键词：广府文化海外华人广东广播电视台拉斯韦尔5W模式

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