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Peritoneal carcinosis of ovarian origin

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World Journal of Gastrointestinal Oncology 2010年第2期2卷 102-108页

作者： anna fagotti Valerio Gallotta Federico Romano Francesco Fanfani Cristiano Rossitto Angelica Naldini Massimo Vigliotta Giovanni Scambia Department of Obstetrics and Gynecology Catholic University of the Sacred Heart

Epithelial ovarian cancer (EOC) is the second most common genital malignancy in women and is the most lethal gynecological malignancy,with an estimated five-year survival rate of 39%.Despite efforts to develop an effective ovarian cancer screening method,60% of patients still present with advanced *** management using surgical cytoreduction to decrease the tumor load to aminimum,and intraperitoneal chemotherapy to eliminate microscopic disease on peritoneal surface,has the potential to greatly improve quality of life and to have an impact on survival in ovarian cancer *** achieving clinical remission after completion of initial treatment,most patients (60%) with advanced EOC will ultimately develop recurrent disease or show drug resistance;the eventual rate of curability is less than 30%.Given the poor outcome of women with advanced EOC,it is imperative to continue to explore novel therapies.

关键词： Peritoneal carcinosis Ovarian cancer Intraperitoneal hyperthermic chemotherapy Cytoreduction

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借助ODS分析对压缩机壳体优化降噪研究

电器 2013年第S1期 780-785页

作者：徐建文 Fabian fagotti 北京恩布拉科雪花压缩机有限公司 101312

无论对压缩机或冰箱,噪声均是一个重要的产品声学性能参数。持续不断地改善压缩机的噪声和声品质,是实现产品性能不断优化及增大差异化市场竞争的关键所在。文中压缩机噪声的降低研究主要集中于壳体优化的环节,工作振型(ODS)是主要运用... 详细信息

无论对压缩机或冰箱,噪声均是一个重要的产品声学性能参数。持续不断地改善压缩机的噪声和声品质,是实现产品性能不断优化及增大差异化市场竞争的关键所在。文中压缩机噪声的降低研究主要集中于壳体优化的环节,工作振型(ODS)是主要运用的优化分析手段。ODS分析关注于机器或结构的实际运行情况,单独利用工作状态或环境激励下的响应信号识别出工作模态参数,其符合实际工况及边界条件,能真实地反映结构在工作状态下的动力学特性。通过此方法,可获得压缩机在实际运行工况的关键分析频率处每一个分析位置的动态特性。对壳体的最大振动变形区域采取优化措施后,压缩机噪声获得明显降低,声品质获得极大优化。

关键词：压缩机壳体优化降噪工作振型

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借助ODS分析对压缩机壳体优化降噪研究

借助ODS分析对压缩机壳体优化降噪研究

腹腔镜评估晚期卵巢癌患者能否行满意的肿瘤细胞减灭术:初步研究

2013年中国家用电器技术大会

作者：徐建文 Fabian fagotti 北京恩布拉科雪花压缩机有限公司

关键词：压缩机壳体优化降噪工作振型

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世界核心医学期刊文摘（妇产科学分册） 2005年第7期1卷 33-34页

作者： fagotti A. Fanfani F. Ludovisi M. G.Scambia 石菁菁 Division of Gynecologic Oncology Cathol. Univ. of the Sacred Heart Largo Agostino Gemelli 8 00168 CampobassoRome Italy

Objective. To investigate whether laparoscopy can be considered as adequate and reliable as standard laparotomy in predicting optimal cytoreduction (RT ≤ .1 cm) in patients with advanced ovarian cancer. Methods. From March to November 2003, 95 patients with suspected advanced ovarian or peritoneal cancer have been evaluated. Thirty- one cases were excluded due to an anesthesiological class of risk ASA III- IV (51.6% ) and for the presence of a large size mass reaching the xiphoid (48.4% ). Sixty- four patients completed the study. All patients were submitted to preoperative clinico- radiological evaluation and then to both laparoscopy and standard longitudinal laparotomy, sequentially. Some specific preoperatively defined parameters were analyzed during each procedure in order to obtain the most accurate evaluation on the possibility to get an optimal cytoreduction. Results. The overall accuracy rate of laparoscopy in assessing optimal cytoreduction was 90% .The negative predictive value (NPV) of the clinical- radio- logic evaluation corresponded to 73% , whereas in no case was the judgment of unresectable disease obtained by laparoscopy changed by the laparotomic approach (NPV 100% ). On the contrary, an optimal debulking was achievable in 34 of 39 cases (87% ) selected as completely resectable by explorative laparoscopy. Conclusions. Laparoscopy can be considered super imposable to standard longitudinal laparotomy in identifying not optimally resectable advanced ovarian cancer patients.

关键词：肿瘤细胞减灭术晚期卵巢癌腔镜腹膜癌开腹手术腹腔镜手术影像学评价临床影像学麻醉学阴性预测值

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小切口开腹术在良性妇科疾病治疗中的应用

世界核心医学期刊文摘（妇产科学分册） 2005年第8期1卷 6-6页

作者： Fanfani F. fagotti A. Longo R. G.Scambia 张剑萍 Dept.Obstet. Gynecol. Intensive C. Cathol. Univ. of the Sacred Heart L.go A. Gemelli 8Rome 00168 Italy

Background: Considering the enormous advantages of minimally invasive surgery, attempts to explore less invasive trans-abdominal incisions could represent an alternative to laparoscopic gynecologic surgery. The aim of this study was to assess the feasibility and clinical outcome of minilaparotomy in a large series of patients. Methods: In this retrospective study we describe our 6-year experience on 252 patients undergoing surgery by minilaparotomy for benign adnexal or uterine disease. Surgical treatments included total abdominal hysterectomy, myomectomy, mono or bilateral salpingo-oophorectomy and adnexal surgery. Results: The mean population age and BMI were 39.2 years (±13.2 S.D.) and 23.6 (±3.31 S.D.), respectively. The mean operative time was 75.4 min (±31.8) and the estimated blood loss was never significant except in two cases (0.8%). The mean duration of ileus was 1.58 days (±0.6 S.D.) and the mean days until discharge were 3.06 (±1.14 S.D.), with a significantly lower duration of recovery in the group of simple adnexal surgery with respect to the others (P = 0.0001). No severe early post-operative morbidity was observed. Conclusions: The current report describes minilaparotomy as a feasible surgical approach in benign gynecological diseases. The operative time is quite similar or shorter than reported for laparoscopy, laparotomy and vaginal surgery. The estimated blood loss is not significant as well as the duration of the ileus and discharge. Moreover, a prospective randomised study, already ongoing in our department, will better answer the question of whether minilaparotomy could be an alternative to laparoscopic and vaginal surgery.

关键词：小切口开腹术妇科疾病附件手术腹腔镜手术经阴道手术剖腹术剥除术临床结局全子宫切除术术中失血量