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Journal of Environmental Sciences 2019年第8期31卷 179-191页

作者： Niloy Chandra Sarker Md Borhan ann-marie fortuna Shafiqur Rahman Agricultural and Biosystems Engineering Department North Dakota State University USDA-ARS Grazinglands Research Laboratory

Manure is an impending source of carbon(C), sulfur(S) and water(H_2 O). Consequently,microbial populations utilize these constituents to produce methane(CH4), carbon dioxide(CO_2), greenhouse gases(GHGs), and hydrogen sulfide(H_2 S). Application of nanoparticles(NPs) to stored manure is an emerging GHG mitigation technique. In this study, two NPs: nano zinc oxide(nZnO) and nano silver(nAg) were tested in swine manure stored under anaerobic conditions to determine their effectiveness in mitigating gaseous emissions and total gas production. The biological sources of gas production, i.e., microbial populations were characterized via Quantitative Polymerase Chain Reaction(qPCR) analysis. Additionally, pH, redox, and VFAs were determined using standard methods. Each treatment of the experiment was replicated three times and NPs were applied at a dose of 3 g/L of manure. Also, headspace gas from all treatment replicates were analyzed for CH_4 and CO_2 gas concentrations using an SRI-8610 Gas Chromatograph and H_2 S concentrations were measured using a Jerome 631 X meter. Nanoparticles tested in this study reduced the cumulative gas volume by 16%–79% compared to the control. Among the NPs tested, only nZnO consistently reduced GHG concentrations by 37%–97%. Reductions in H_2 S concentrations ranged from 87% to97%. Gaseous reductions were likely due to decreases in the activity and numbers of specific gas producing methanogenic archaea and sulfate reducing bacterial(SRB)species.

关键词： Swine manure Nanoparticles Greenhouse gas Methanogen Sulfate reducing bacteria(SRB)

Fever of unknown origin:a retrospective review of pediatric patients from an urban,tertiary care center in Washington,DC

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World Journal of Pediatrics 2020年第2期16卷 177-184页

作者： ann marie Szymanski Hugo Clifford Tova Ronis Division of Pediatric Rheumatology Children's National Health SystemWashingtonDCUSA National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institutes of HealthBuilding 10Rm 12S251 MSC 156010 Center DriveBethesdaMD 20814USA The School of Medicine and Health Sciences The George Washington UniversityWashingtonDCUSA

Background Fever of unknown origin(FUO)continues to challenge clinicians to determine an etiology and the need for *** study explored the most common etiologies,characteristics,and average cost of hospitalization for FUO in a pediatric population at an urban,tertiary care hospital in Washington,*** Records from patients admitted to Children's National Health System between September 2008 and April 2014 with an admission ICD-9 code for fever(780.6)were *** charts of patients 2-18 years of age with no underlying diagnosis and a temperature greater than 38.3℃for 7 days or more at time of hospitalization were *** diagnoses,features of admission,and total hospital charges were *** 110 patients qualified for this *** majority of patients(n=42,38.2%)were discharged without a *** was followed closely by infection,accounting for 37.2%(n=41)of *** disease was next(n=16,14.5%),followed by miscellaneous(n=6,5.4%)and oncologic diagnoses(n=5,4.5%).The average cost of hospitalization was 40,295 US *** This study aligns with some of the most recent publications which report undiagnosed cases as the most common outcome in patients hospitalized with *** that,often no diagnosis is found may reassure patients,families,and *** cost associated with hospitalization for FUO may cause clinicians to reconsider inpatient admission for diagnostic work-up of fever,particularly given the evidence demonstrating that many patients are discharged without a diagnosis.

关键词： Fever Fever of unknown origin Infection Healthcare costs

Development of a brownfield inventory for prioritizing funding outreach in Tucson,Arizona

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Geo-Spatial Information Science 2021年第4期24卷 742-754页

作者： Theresa Foley ann marie Wolf Chloe Jackson Ryan Stephenson Sonora Environmental Research Institute Inc.(SERI)TucsonAZUSA Pima County ITD/GIS TucsonAZUSA Pima County Community Development&Neighborhood Conservation TucsonAZUS

Fear of liability from the 1980 Comprehensive Environmental Response,Compensation,and Liability Act(CERCLA or Superfund)has prompted developers to build preferentially upon undeveloped green space rather than potentially contaminated former industrial sites,leading to urban sprawl in the suburban areas while blighted properties in the urban core remain vacant.A brownfield is defined as a property in which the presence or potential presence of a hazardous substance or contaminant poses a barrier to *** often create brownfield inventories by performing a site suitability analysis,using distinguishing features such as ecolo-gically and culturally significant areas or neighborhoods that need *** County,Arizona and the Sonora Environmental Research Institute,Inc.(SERI)developed a brownfield inventory of the large,industrial area directly to the west of Davis-Monthan Air Force *** the brownfield target area has few residential neighborhoods and lacks the distinguish-ing features usually used in a brownfield site suitability analysis,the county and SERI used the official tax assessor database and 11 federal,state and county environmental databases to develop a brownfield *** goal of the project was to prioritize properties that stood to benefit from the grant *** final brownfield inventory contained 531 parcels.

关键词： GIS site suitability analysis brownfield urban planning brownfield inventory

Silkworm silk biomaterials for spinal cord repair: promise for combinatorial therapies

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Neural Regeneration Research 2018年第5期13卷 809-810页

作者： anna Varone ann marie Rajnicek Wenlong Huang Institute of Medical Sciences University of Aberdeen

Background：Traumatic injury to the adult mammalian spinal cord results in minimal axonal regrowth,cystic cavity formation at the injury site,poor functional recovery and there is no cure *** to the complex nature of spinal cord injury（SCI）,a combination of therapeutic strategies may offer the most promise for successful regeneration（Ahuja et al.,2017）.

关键词： SCI Figure Silkworm silk biomaterials for spinal cord repair promise for combinatorial therapies

Respiratory supercomplexes:structure,function and assembly

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Protein & Cell 2013年第8期4卷 582-590页

作者： Rasika Vartak Christina ann-marie Porras Yidong Bai Department of Cellular and Structural Biology University of Texas Health Science Center at San AntonioSan AntonioTX 78229USA

The mitochondrial respiratory chain consists of 5 enzyme complexes that are responsible for ATP *** paradigm of the electron transport chain as discrete enzymes diffused in the inner mitochondrial membrane has been replaced by the solid state supercomplex model wherein the respiratory complexes associate with each other to form supramolecular *** in these supercomplexes,which have been shown to be functionally active and required for forming stable respiratory complexes,have been associated with many genetic and neurodegenerative disorders demonstrating their biomedical signifi *** this review,we will summarize the functional and structural signifi cance of supercomplexes and provide a comprehensive review of their assembly and the assembly factors currently known to play a role in this process.

关键词： supercomplex mitochondrial respiration

Monomer-activated Copolymerization of Ethylene Oxide and Epichlorohydrin: In Situ Kinetics Evidences Tapered Block Copolymer Formation

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Chinese Journal of Polymer Science 2019年第9期37卷 912-918页

作者： ann-Kathrin Danner Daniel Leibig Lea-marie Vogt Holger Frey Institute of Organic Chemistry Johannes Gutenberg- Universitat Mainz Duesbergweg 10-14 55128 Mainz Germany Graduate School Materials Science in Mainz Staudinger Weg 9 55128 Mainz Germany

The monomer-activated anionic ring-opening copolymerization (AROP) of ethylene oxide (EO) and epichlorohydrin (ECH) using tetraoctylammonium bromide as an initiator and triisobutylaluminum (i-Bu3Al) as an activator was studied. The properties of the copolymers as well as the microstructure have been analyzed in detail via an in situ NMR kinetics study. The statistical copolymers exhibited molecular weights ranging from 2350 g·mol^-1 to 38000 g·mol^-1 (measured by SEC, PEG-standards) and moderate dispersities of 1.27-1.44. The thermal property tests revealed both a glass transition and melting for all copolymers, supporting a block-like nature. Applying in situ NMR kinetic measurements, the reactivity ratios of EO and ECH were determined to be strongly disparate, i.e., rEo = 9.2 and rECH = 0.10. This shows that the simple one-pot statistical anionic copolymerization of EO and ECH via the monomer-activated AROP resulted in the formation of strongly tapered, block-like structures. Furthermore, post-polymerization functionalization of the reactive chloromethyl groups by nucleophilic displacement was investigated for the copolymers. Copolymerization of EO and ECH offers a broad platform for further functionalization and therefore the possibility to prepare a variety of multifunctional PEGs.

关键词： Epichlorohydrin Polymerization Ring-opening Copolymerization Reactivity ratios Epoxide

Surrogate-based modeling and dimension reduction techniques for multi-scale mechanics problems

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Acta Mechanica Sinica 2011年第6期27卷 845-865页

作者： Wei Shyy Young-Chang Cho Wenbo Du Amit Gupta Chien-Chou Tseng ann marie Sastry Hong Kong University of Science and Technology Clear Water Bay Hong Kong China University of Michigan Ann Arbor MI USA National Taiwan Sun Yat-Sen University Kaohsiung Taiwan China

Successful modeling and/or design of engineering systems often requires one to address the impact of multiple ＂design variables＂ on the prescribed *** are often multiple,competing objectives based on which we assess the outcome of *** accurate,high fidelity models are typically time consuming and computationally expensive,comprehensive evaluations can be conducted only if an efficient framework is ***,informed decisions of the model/hardware＇s overall performance rely on an adequate understanding of the global,not local,sensitivity of the individual design variables on the *** surrogate-based approach,which involves approximating the objectives as continuous functions of design variables from limited data,offers a rational framework to reduce the number of important input variables,i.e.,the dimension of a design or modeling *** this paper,we review the fundamental issues that arise in surrogate-based analysis and optimization,highlighting concepts,methods,techniques,as well as modeling implications for mechanics *** aid the discussions of the issues involved,we summarize recent efforts in investigating cryogenic cavitating flows,active flow control based on dielectric barrier discharge concepts,and lithium（Li）-ion *** is also stressed that many multi-scale mechanics problems can naturally benefit from the surrogate approach for ＂scale bridging.＂

关键词： Multi-scale mechanics ~ Cryogenic cavitating flow Surrogate-based modeling Active flow control Engineering system

Fulminant liver failure models with subsequent encephalopathy in the mouse

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Hepatobiliary & Pancreatic Diseases International 2011年第6期10卷 611-619页

作者： ann-marie T Baine Tomohide Hori Lindsay B Gardner Shinji Uemoto Justin H Nguyen Department of Neuroscience Mayo Clinic in Florida JacksonvilleFL 32224USA Divisions of Hepato-Pancreato-Biliary Transplant and Pediatric SurgeryDepartment of SurgeryKyoto University Graduate School of MedicineKyoto 606-8507Japan Division of Transplant Surgery Department of TransplantationMayo Clinic in FloridaJacksonvilleFL 32224USA

BACKGROUND:A reliable model of fulminant liver failure (FLF) is urgently required in this research *** study aimed to develop a murine FLF ***:We used three groups of male C57BL/6 mice:control,with azoxymethane treatment (AOM group),and with galactosamine and tumor necrosis factor-alpha treatment (Gal+TNF-α group).The effects of body temperature (BT) control on survival in all three groups were investigated Using BT control,we compared the survival,histopathological findings and biochemical/coagulation profiles between the two experimental *** effects of hydration on international normalized ratios of prothrombin time (PT INRs) were also ***-dependent survival curves were constructed for both experimental *** behavior was assessed using a coma ***:No unexpected BT effects were seen in the control *** AOM group,but not the Gal+TNF-α group showed a significant difference in survival curves between those with and without BT *** assessment showed consistent FLF findings in both experimental groups with BT *** were significant differences between the experimental groups in aspartate aminotransferase levels and PT-INRs,and significant differences in PT-INRs between the sufficiently and insufficiently hydrated *** were significant differences between FLF models in the duration of each coma stage,with significant differences in stages 1 and 3 as percentages of the disease state (stages 1-4).The two FLF models with BT care showed different survival curves in the dose-dependent survival ***:AOM provides a good FLF model,but requires a specialized environment and careful BT *** FLF models may also be useful,depending on the research *** attention to caregiving and close observation are indispensable for successful FLF models.

关键词： animal model acute liver failure azoxymethane galactosamine tumor necrosis factor-alpha

Continued circulation of a single genotype of dengue virus serotype 2 in the Philippines

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Asian Pacific Journal of Tropical Medicine 2014年第1期7卷 30-33页

作者： Joy ann G Petronio Ricky B Vinarao Kristine marie G Flores Raul V Destura Institute of Molecular Biology and Biotechnology National Institutes of Health-University of the PhilippinesManila Section of Molecular Diagnostics The Medical CityPhilippines

Objective:To obtain descriptive information of behavioral pattern in Chinese school-aged children with cleft lip and ***:A total of 93 cleft lip and palate patients between the age of 6-11 year-old and treated at West China Stomatology Hospital were *** another100 unaffected controls,matched for age and gender,were recruited randomly from a common primary school in *** review of medical records was used to obtain psychosocial *** were compared with published norms and controls to evaluate the risk of problems,separately for three diagnostic ***:The patients group had lower scores of social and academic competencies,especially those with facial deformity or speech *** difference was found in the aspect of activity *** patients showed elevations in behavior *** the type of behavior problems varied in different ***:Chinese school-aged children with cleft lip and palate are at raised risk for social and academic *** pattern of behavior problems displays differently depending on gender of the patient.

关键词： Cleft lip and palate CBCL Psychosocial adjustment Behavior problems

Mobilities, Identities and Diversities: Contemporary Interpretations of a Canonical Chinese Play in Singapore

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Sociology Study 2020年第3期10卷 141-148页

作者： ann-marie Hsiung Department of Applied English I-Shou UniversityTaiwan

Globalization increases mobilities and multiplies identities in ***,a city state with diverse Asian communities,amplifies this *** the 1990s,Singapore recruited large numbers of Western educated Chinese scholars,who formed new diasporas across Asia and became catalyst for further cultural *** multifaceted Asian phenomenon can be best exemplified in Chinese scholar-director Grant Shen’s contemporary productions of the traditional Chinese opera—The West Wing(2008,2016).This study discusses issues of mobilities,identities,and diversities through The West Wing,in which the performers are predominantly from Asian *** mobility of Grant Shen from China to Singapore via the US diversifies his cultural identity,at once rooted deeply in Chinese culture while openly embracing Western liberalism and Singaporean *** theatre productions,boldly adopting pop music,employing trendy language,and recreating pro-feminist scenes,vividly attest to cultural *** issues come to the fore when this well-received play in Singapore toured Shanghai,where it was welcomed by the young but frowned upon by others as subversive to Chinese *** study views the multiplicity of Singapore as a fertile land for productions foretelling the plural future Asia.

关键词： mobilities identities cultural diversities scholar-director canonic drama