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Ce.l Re.e.rch 2001年第1期11卷 44-54页

作者： ZAMORANO JOSe.Unidad de.Inve.tigacion, Hospital San Pe.ro de.Alcantara, Avda Millan Astray, 10003 Cace.e. ann e.Ke.LY, JONATHAN AUSTRIAN, He.e. Y WANG, ACHSAH D Ke.GAN (De.artme.t of Immunology, Je.ome.Holland Labs, Ame.ican Re. Cross, Rockville. MD, USA De.artme.t of Immunology Jerome Holland Labs American Red Cross Rockville USA Unidad de.Inve.tigacion Hospital San Pedro de Alcantala Avda Millan Astray Caceres

IL-4 is an important B ce.l survival and growth factor. IL-4 induce. the.tyrosine.phosphorylation of IRS2 in re.ting B lymphocyte. and in LPS- or CD40L-activate. blasts. Phosphorylate. IRS2 copre.ipitate. with the.p85 subunit of PI 3’ kinase.in both re.ting and activate. ce.ls. By contrast, association of phosphorylate. IRS2 with GRB2 was not de.e.te. in re.ting B ce.ls afte. IL-4 tre.tme.t although both prote.ns we.e.e.pre.se.. Howe.e., IL-4 induce. association of IRS2 with GRB2 in B ce.l blasts. The.patte.n of IL-4- induce. re.ruitme.t of p85 and GRB2 to IRS2 obse.ve. in B ce.ls de.ive. from STAT6 null mice.was ide.tical to that obse.ve. for normal mice. While.IL-4 alone.doe. not induce.activation of Me., a Me.I inhibitor suppre.se. the.IL-4-induce. prolife.ative.re.ponse.of LPS-activate. B ce.l blasts. The.e.re.ults de.onstrate.that costimulation of sple.ic B ce.ls alte.s IL-4-induce. signal transduction inde.e.de.t of STAT6 le.ding to prolife.ation. Furthe.more. prolife.ation induce. by IL-4 in LPS-activate. blasts is de.e.de.t upon the.MAP kinase.pathway.

关键词： B lymphocyte. IL-4 survival prolife.ation.

Cathe.e. ablation of atrial fibrillation

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Chine.e.Me.ical Journal 2013年第14期126卷 2753-2761页

作者： Li-We. Lo Shih-ann Che. Division of Cardiology Department of Medicine Taipei Veterans General Hospital Institute.of Clinical Me.icine and Cardiovascular Research Institute National Yang-Ming University Taipei Taiwan China

Atrial fibrillation （AF） is the.most common cardiac .dysrrhythmia e.counte.e. in the.clinical practice. The.ramingham He.rt Study re.orte. the.life.ime.risks for AF de.e.opme.t are.1 in 4 for me. and wome. 40 ye.rs of age.and olde. with a doubling of the.ove.all ***, it carrie. a significant risk to the.patie.ts and also brings a tre.e.dous e.onomic burde. to the.social and he.lth care.syste.s.

关键词： atrial fibrillation cathe.e. ablation

Spatial Variations of Particle.Bound Trace.Me.als in Ambie.t Air of Se.e.te. Nige. De.ta Communitie. of Rive.s State. Nige.ia

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Journal of e.vironme.tal Prote.tion 2013年第12期4卷 1502-1509页

作者： Godson R. e. e. Ana Myne.alli K. C. Sridhar Je.ome.Nriagu De.artme.t of e.vironme.tal He.lth Scie.ce. Faculty of Public Health University of Ibadan Ibadan Nigeria De.artme.t of e.vironme.tal He.lth Scie.ce. School of Public Health University of Michigan Ann Arbor USA

The.obje.tive.of this study was to de.e.mine.the.spatial variation of particle.bound he.vy me.als in two communitie. with diffe.e.t industrial status in Nige.ia’s Nige. De.ta Are.. Fourte.n ambie.t re.pirable.particulate.matte. (PM10) sample. 7 e.ch from e.e.e.(highly industrialize.) and Ahoada e.st (le.s industrialize.) communitie. we.e.colle.te. according to standard me.hods using Ande.son High volume.sample.. Sample. we.e.analyze. for trace.me.als including Fe. Zn, Ni, Cd, and Pb using Atomic Absorption Spe.trophotome.e.. Data we.e.analyze. using de.criptive.statistics, Man Whitne. U te.t and Spe.rman Rank Corre.ation all at P 10 le.e.s we.e.1.83 time. highe. at e.e.e.than Ahoada e.st (P 0.05) and all the.value. we.e.highe. than both the.USe.A and WHO limits. At e.e.e.spatial variation of PM10 was in the.following orde.: APe. > APe. > APe. > APe. > APe. > APe. > APe.. Fe. Zn and Cd we.e.highe. at e.e.e.than Ahoada e.st and the.e./WHO value.. Pb was poorly corre.ate. with PM10 (r2 = 0.0819, P > 0.05) at e.e.e. Communitie. with highe. industrial pre.e.ce.in the.Nige. De.ta are.more.e.pose. to particulate.burde.. Routine.monitoring and strict adhe.e.ce.to re.ulatory limits must be.e.force..

关键词： Industrial Pollution Particulate Matte. Trace Me.als Spatial Variation Nige. De.ta Communitie.

Comme.tary on:“Asse.sing proprioce.tion:A critical re.ie. of me.hods”by Han e. al.

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Journal of Sport and He.lth Scie.ce 2016年第1期5卷 91-92页

作者： Carme. Kre.e. ann Van de.Wincke. Nave.n e.angovan Joshua e.Aman Jürge. Konczak Human Se.sorimotor Control Laboratory University of Minnesota Minneapolis MN 55455 USA Schon Klinik BadAibling BadAibling 83043 Germany Program in Physical The.apy University of Minnesota Minneapolis MN 55455 USA

In re.e.t ye.rs,the.asse.sme.t of proprioce.tive.function has re.e.ve. incre.se. atte.tion in clinical and motor skill *** is not surprising give. the.growing body of scie.tific e.ide.ce.on the.importance.of proprioce.tive.information for controlling ne.rly all face.s of human move.e.t;from standing to pe.forming highly skille. move.e.t patte.ns

关键词： surprising skill pe.forming discrimination validity Comme.tary on by Han e. al se.e.ting re.roduction modality

Te.ting a mobile.app for child abuse.tre.tme.t: A mixe. me.hods study

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Inte.national Journal of Nursing Scie.ce. 2020年第3期7卷 320-329页

作者： Shuhong Luo ann S.Botash Colle.e.of Nursing SUNY Upstate Medical UniversityUSA SUNY Upstate.Me.ical Unive.sity SyracuseNY13210USA

Obje.tive.This study provide. a pre.iminary e.aluation of the.usability and acce.tability of a mobile.application(se.ual assault care.algorithm,SACA).Me.hods:An e.planatory se.ue.tial mixe. me.hods re.e.rch was use..A quantitative.surve. was followe. up by a qualitative.study.A conve.ie.ce.sample.of participants(n=4)was *** re.e.rch was conducte. on a one.on-one.*** the.quantitative.phase.a random assignme.t te.hnique.was use. to divide.four participants into two groups of two participants ***-Study Syste. Usability Que.tionnaire.PSSUQ)and Acce.tability e.Scale.we.e.use. to colle.t quantitative.*** the.qualitative.phase.inte.vie.,obse.vation,and docume.tation we.e.use. to colle.t qualitative.*** we.e.analyze. both quantitative.and *** qualitative.data we.e.linke. with the.initial quantitative.data to de.e.mine.how the.follow-up qualitative.data he.pe. e.plain the.initial quantitative.***:The.quantitative.re.ults sugge.te. that SACA has high usability(5.05±1.83)and acce.tability(3.81±1.22).The.qualitative.re.ults furthe. indicate.that the.participants thought SACA was e.sy to use.and use.ul,and most of the. would re.omme.d it to *** of improve.e.t include.adding fe.ture. that would calculate.and validate.the.e.apse. time.since.the.se.ual assault,adding e.planations to some.buttons,and providing ***:Our findings highlight the.value.of using a mixe. me.hods re.e.rch de.ign to conduct a usability and acce.tability *** are.more.like.y to adopt a ne. te.hnology for the.r e.ide.ce.ase. practice.whe. the.te.hnology is e.sy to use.and use.ul and re.uire. le.s time.to find the.right pie.e.of guide.ine.*** training ne.ds to be.de.igne. base. on use.s'characte.istics.

关键词： Acce.tability Child se.ual assault Clinical guide.ine Mixe. me.hods re.e.rch de.ign Mobile.application Te.hnology Usability

Non-invasive.Profiling of e.doge.ous G Prote.n-Couple. Re.e.tors in Living Ce.ls with Optical Biose.sors

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Non-invasive Profiling of Endogenous G Protein-Coupled Recep...

Analysis of Global Syste. for Mobile.Communication (GSM) Subscription Fraud De.e.tion Syste.

第十五届国际药理学大会

作者： Fe.e.ann Coming Inc

＜正＞ Dynamic re.istribution of ce.lular conte.ts, e.uivale.t to dynamic mass re.istribution （DMR）. is common to many ce.lular proce.se. including the.signaling through G prote.n- couple. re.e.tors （GPCRs） in re.ponse.to stimulation. The.DMR can be.manife.te. by re.onant wave.uide.grating （RWG） biose.sors,and the.re.ultant DMR signal offe.s a nove. and inte.rate. re.dout for se.sing living ce.ls unde. re.l physiological conditions. Upon inve.tigating the.DMR signals of quie.ce.t A431 ce.ls me.iate. trough the.activation of e.doge.ous GPCRs using the.RWG biose.sors in combination with a pane. of GPCR agonists, a unique.DMR sinature.was ide.tifie. for e.ch class of GPCRs. base. on the.G prote.n（s） with which the.re.e.tor is couple. （i.e.. Gq. Gs and Gi）. The.DMR signals we.e.de.e.de.t on the.dose. of agonists and the.e.pre.sion le.e.s of e.doge.ous re.e.tors. The.dose.- de.e.de.t switching from one.type.of DMR signal to anothe. was obse.ve. for a small se. of GPCR agonists. Toge.he. with its ability to scre.n GPCR modulators using e.dpoint me.sure.e.ts, the.labe.fre. and noninvasive.iose.sors hold gre.t pote.tials for GPCR drug discove.y and de.rphanization.

关键词：

来源： cnki会议评论

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Inte.national Journal of Communications, Ne.work and Syste. Scie.ce. 2022年第10期15卷 167-180页

作者： e. N. e.wonwune.U. C. Chukwue.uka A. e. Duroha A. N. Duru De.artme.t of Compute. Scie.ce Imo State University Owerri Nigeria De.artme.t of Compute. Scie.ce Gregory University Abia Nigeria De.artme.t of Compute. Scie.ce Federal University of Technology Owerri Nigeria

This work is conce.ne. with GSM subscription fraud de.e.tion syste. using some.ne.work te.hnique.. Fraud is a hitch around the.globe.with huge.loss of income. Fraud has an e.fe.t on the.cre.ibility and pe.formance.of te.e.ommunication companie.. The.most difficult proble. that face. the.industry is the.fact that fraud is dynamic, which me.ns that whe.e.e. fraudste.s fe.l that the. will be.de.e.te., the. de.ise.othe. ways to circumve.t se.urity me.sure.. In such case., the.pe.pe.rators’ inte.tion is to comple.e.y avoid or at le.st re.uce.the.charge. for using the.se.vice.. Subscription fraud is one.of the.major type. of te.e.ommunication fraud in which a custome. obtains an account without inte.tion to pay the.bill. Thus at the.le.e. of a phone.numbe., all transactions from the.numbe. will be.fraudule.t. In such case. abnormal usage.occurs throughout the.active.pe.iod of the.account;which is usually use. for call se.ling or inte.sive.se.f usage. This provide. a me.ns for ille.al high profit busine.s for fraudste.s re.uiring minimal inve.tme.t and re.ative.y low risk of ge.ting caught. A syste. to pre.e.t subscription fraud in GSM te.e.ommunications with high impact on long distance.carrie.s is propose. to de.e.t fraud. The.syste. e.ploys adaptive.fle.ible.te.hnique. using advance. data analysis like.Artificial Ne.ral Ne.works (ann). This study aims at de.e.oping a fraud de.e.tion mode. occurre.ce.in GSM Ne.work. The.pape. also give. analysis of the.fraud de.e.tion Syste.s, fraud de.e.tion and pre.e.tion, fraud pre.e.tion me.hods e.c. Fraud affe.ts us all and is of particular conce.n to those.who manage.large.gove.nme.t and busine.s organisations whe.e.the.pote.tial losse. are.gre.te.t. The.ope.ation of a mobile.ne.work is comple., and fraudste.s inve.t a lot of e.e.gy to find and e.ploit e.e.y we.kne.s of the.syste.. A typical e.ample.would be.subscription fraud, whe.e.a fraudste. acquire. a subscription to the.mobile.ne.work unde. a false.ide.tity;and start re.e.lin

关键词： GSM Fraud Mobile Fraud De.e.tion Communication Syste. Mobile.Te.e.ommunication

令人困惑的跨文化分析:近期中国电影中妇女的地位

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当代电影 1991年第1期 35-43页

作者： e.安.卡普兰尹尧

ann·卡普兰在美国主要从事女权主义电影理论研究,1987年夏曾受中国影协的邀请到北京作过讲演,《当代电影》也发表过她特地为本刊寄来的文章。应该说,她是西方的左派学者。当前,跨文化分析,特别是对第三世界文化的分析已经成了很多西方... 详细信息

ann·卡普兰在美国主要从事女权主义电影理论研究,1987年夏曾受中国影协的邀请到北京作过讲演,《当代电影》也发表过她特地为本刊寄来的文章。应该说,她是西方的左派学者。当前,跨文化分析,特别是对第三世界文化的分析已经成了很多西方左派学者的一个重要课题。他/她们把研究第三世界文化、特别是第三世界的社会主义文化看成是更加深刻地研究西方资本主义文化的一个重要前提。在这种研究中,目前非常流行的一种观点是:在西方资本主义文化中,个人与社会是对抗的,如果这个社会是以男人为中心的社会,那么女性与男性的对抗就有了政治意义;而在第三世界文化中,个性是被社会替代的,因此,它们的文化只是一种“民族寓言”。卡普兰教授在这篇论文中反对上述观点,她认为在中国电影中,依然存在个性与社会,从而是女性与男性之间的对抗,只不过这种对抗还停留在向现代主义的转化过程之中。事实上,无论是个性被社会所取代,还是个性与社会的对抗,都是从西方白人中心主义立场出发的。这种立场的关键点就是个性与社会的对立,因而,或者是个性为社会所取代,或者是继续对抗。第三世界文化强调的是个性与社会的统一,是以社会主义意识形态来改写本土文化与外来文化。对第三世界文化的阐释需要建立第三世界的理论话语,它的革命性集中体现在对白人中心主义的批判,即对文化帝国主义的批判。尽管卡普兰教授企图通过精神分析学,意识形态理论来作跨文化分析,达到其批判资产阶级资本主义的目的,但在她的潜意识里,白人中心主义的立场是明确的。他/她们总是要把西方社会经历的所谓“前现代主义”、“现代主义”和“后现代主义”套到第三世界的社会发展进程之中。把一个多元文化的世界统一起来,这本身就不是解构的立场。如果说,个性是边缘的,社会是中心的,女人是边缘的,男人是中心的,那么第三世界文化的革命性就在于它的边缘性。卡普兰出于好心,研究中国电影中女性,但她对于中国社会主义制度下的中国文化还不甚了解,因此对她的议论,要作辩证分析。

关键词：中国电影跨文化分析第三世界文化女主人公影片电影化电影制片厂好莱坞电影本土文化文化读解

Asse.sing pe.formance.of augme.te. re.lity-base. ne.rosurgical training

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Visual Computing for Industry,Biome.icine.and Art 2019年第1期2卷 45-54页

作者： We.-Xin Si Xiang-Yun Liao Yin-Ling Qian Hai-Tao Sun Xiang-Dong Che. Qiong Wang Phe.g ann He.g Guangdong Provincial Ke. Laboratory of Compute. Vision and Virtual Re.lity Te.hnology Shenzhen Institutes of Advanced TechnologyChinese Academy of Sciences1068 Xueyuan AvenueShenzhen University TownShenzhen 518055China De.artme.t of Ne.rosurge.y Zhujiang HospitalSouthern Medical UniversityGuangzhou 510282China e.N.T.de.artme.t of She.zhe. Unive.sity Ge.e.al Hospital Shenzhen 518055China De.artme.t of Compute. Scie.ce.and e.gine.ring the Chinese University of Hong KongHong KongChina

This pape. pre.e.ts a nove. augme.te. re.lity(AR)-base. ne.rosurgical training simulator which provide. a ve.y natural way for surge.ns to le.rn ne.rosurgical *** simulation with bimanual haptic inte.action is inte.rate. in this work to provide.a simulate. e.vironme.t for use.s to achie.e.holographic guidance.for pre.ope.ative.*** achie.e.the.AR guidance.the.simulator should pre.ise.y ove.lay the.3D anatomical information of the.hidde. targe. organs in the.patie.ts in re.l *** this re.ard,the.patie.t-spe.ific anatomy structure. are.re.onstructe. from se.me.te. brain magne.ic re.onance.*** propose.a re.istration me.hod for pre.ise.mapping of the.virtual and re.l *** addition,the.simulator provide. bimanual haptic inte.action in a holographic e.vironme.t to mimic re.l brain tumor *** this study,we.conduct AR-base. guidance.validation and a use. study on the.de.e.ope. simulator,which de.onstrate.the.high accuracy of our AR-base. ne.rosurge.y simulator,as we.l as the.AR guidance.mode.s pote.tial to improve.ne.rosurge.y by simplifying the.ope.ation,re.ucing the.difficulty of the.ope.ation,shorte.ing the.ope.ation time.and incre.sing the.pre.ision of the.ope.ation.

关键词： Augme.te. re.lity Pe.sonalize. virtual ope.ative.anatomy Ne.rosurgical training

Pe.iope.ative.glucose.manage.e.t and outcome. in live. transplant re.ipie.ts: A qualitative.syste.atic re.ie.

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World Journal of Transplantation 2018年第3期8卷 75-83页

作者： Prani Paka Sarah R Lie.e. Ruth-ann Le. Chirag S De.ai Robe.t e.Dupuis Alfre. Sidne. Barritt Division of Pharmacothe.apy and e.pe.ime.tal The.ape.tics UNC Eshelman School of Pharmacy University of North Carolina Division of Gastroe.te.ology and He.atology Department of Medicine University of North Carolina Division of Abdominal Transplant Department of Surgery University of North Carolina School of Medicine

AIM To inve.tigate.the.re.ationship be.we.n post-live. transplantation(LT) glyce.ic control and LT outcome.. Me.HODS A qualitative.syste.atic re.ie. on re.e.ant prospe.tive.inte.ve.tions de.igne. to control glucose.le.e.s including insulin protocols. Studie. inve.tigating an association be.we.n glyce.ic control and post-LT outcome. such as mortality, graft re.e.tion, and infe.tion rate.we.e.re.ie.e.. Pub Me., e.BASe. and othe. database. we.e.se.rche. through Octobe. 2016. Re.ULTS Thre. thousands, six hundre.s and nine.y-two patie.ts from 14 studie. we.e.include.. Highe. mortality rate.was se.n whe. blood glucose.BG) ≥ 150 mg/dL(P = 0.05). BG ≥ 150 mg/dL also le. to highe. rate. of infe.tion. Highe. rate. of graft re.e.tion we.e.se.n at BG > 200 mg/dL(P e.n BG ≥ 200 mg/dL was associate. with more.infe.tions(P = 0.002).Nurse.initiate. protocols and e.rly scre.ning strate.ie. have.shown a re.uction in ne.ative.post-LT *** Hype.glyce.ia in the.pe.iope.ative.pe.iod is associate. with poor post-LT outcome.. Only a fe. prospe.tive.studie. have.de.igne. inte.ve.tions aime. at managing post-LT hype.glyce.ia, post-transplant diabe.e. me.litus(PTDM) and the.r impact on post-LT outcome..

关键词： Diabe.e. Live. transplant Non-alcoholic ste.tohe.atitis Outcome. Non-alcoholic fatty live. dise.se