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城市环境设计 2010年第1期 75-81页

作者： Jan Willem van Kuilenburg Kristine Birch Bald Paolo Faleschini Francisco Javier Casas Cobo Beatriz Villanueva Cajide ann carolyn wright Monolab

Monolab建于1999年,目标是高级建筑和城市规划的研究。简易和实验是Monolab的主题。Monolab致力于通过提供高效、清晰的概念和先进的分析手段,综合当代文化处理复杂的项目Monolab设计领域广泛:从家具设计到别墅,由住宅项目、城市计划从... 详细信息

Monolab建于1999年,目标是高级建筑和城市规划的研究。简易和实验是Monolab的主题。Monolab致力于通过提供高效、清晰的概念和先进的分析手段,综合当代文化处理复杂的项目Monolab设计领域广泛:从家具设计到别墅,由住宅项目、城市计划从车站和城市中心到销售中心。

关键词：城市规划城市建设当代文化住宅项目家具设计海事艾瑟尔别墅 Lake 岛屿项目带动

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Performance Evaluation of Small-channel Pulsating Heat Pipe Based on Dimensional Analysis and ann Model

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Energy Engineering 2022年第2期119卷 801-814页

作者： Xuehui Wang Edward wright Zeyu Liu Neng Gao Ying Li Fluids and Thermal Engineering Research Group Faculty of EngineeringUniversity of NottinghamNottinghamNG72RDUK Ningbo Tech University Ningbo315100China Research Centre for Fluids and Thermal Engineering University of Nottingham Ningbo ChinaNingbo315100China

The pulsating heat pipe is a very promising heat dissipation device to address the challenge of higher heat-flux electronic chips,as it is characterised by excellent heat transfer ability and flexibility for *** boost the application of PHP,reliable heat transfer performance evaluationmodels are especially *** this paper,a heat transfer correlation was firstly proposed for closed PHP with various working fluids(water,ethanol,methanol,R123,acetone)based on collected experimental *** analysis was used to group the *** was shown that the average absolute deviation(AAD)and correlation coefficient(r)of the correlation were 40.67%and 0.7556,*** 95%of the data,the prediction of thermal resistance and the temperature difference between evaporation and condensation section fell within 1.13K/Wand 40.76K,***,an artificial neural networkmodelwas also *** ann model showed a better prediction accuracy with a mean square error(MSE)and correlation coefficient(r)of 7.88e-7 and 0.9821,respectively.

关键词： Pulsating heat pipe oscillation heat transfer correlation ann model

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EGFR signaling promotes resistance to CHK1 inhibitor prexasertib in triple negative breast cancer

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Cancer Drug Resistance 2020年第4期3卷 980-991页

作者： Kevin J.Lee Griffin wright Hannah Bryant Leigh ann Wiggins Michele Schuler Natalie R.Gassman Department of Physiology and Cell Biology University of South Alabama College of MedicineMobileAL 36688USA Mitchell Cancer Institute University of South AlabamaMobileAL 36604USA Department of Comparative Medicine University of South Alabama College of MedicineMobileAL 36688USA Department of Microbiology and Immunology University of South Alabama College of MedicineMobileAL 36688USA

Aim:Innate resistance to the CHK1 inhibitor prexasertib has been described,but resistance mechanisms are not *** aimed to determine the role epidermal growth factor receptor(EGFR)plays in innate resistance to prexasertib in triple negative breast cancer(TNBC).Methods:Using a panel of pre-clinical TNBC cell lines,we measured the sensitivity to *** examined the effect activation of EGFR had on prexasertib *** measured the synergy of dual blockade of EGFR with erlotinib and CHK1 with prexasertib in TNBC cell lines and ***:EGFR overexpression and activation increased resistance to CHK1 inhibition by *** promoted the phosphorylation of BCL2-associated agonist of cell death(BAD),inactivating its pro-apoptotic *** of EGFR reversed BAD phosphorylation,increasing sensitivity to ***:The use of prexasertib as a monotherapy in TNBC has been limited due to modest clinical *** demonstrated that EGFR activation contributes to innate resistance to prexasertib in TNBC and potentially other *** expression status should be considered in clinical trials examining prexasertib’s use as a monotherapy or combination therapy.

关键词： Triple negative breast cancer CHK1 replication apoptosis drug resistance epidermal growth factor receptor mitogenic signaling

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Polistes metricus queens exhibit personality variation and behavioral syndromes

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Current Zoology 2018年第1期64卷 45-52页

作者： Colin M. wright Trevor D. HYLAND Amanda S. IZZO Donna R.MCDERMOTT Elizabeth A. TIBBETTS Jonathan N. PRUITT Department of Ecology Evolution and Marine Biology University of California at Santa Barbara Santa Barbara CA 93106 USA Department of Wildlife Fish and Conservation Biology University of California at Davis Davis CA 95616 USA Ecology and Evolutionary Biology University of Michigan Ann Arbor MI 48109-1048 USA

Consistent differences in behavior between individuals, otherwise known as animal personalities, have become a staple in behavioral ecology due to their ability to explain a wide range of phenomena. Social organisms are especially serviceable to animal personality techniques because they can be used to explore behavioral variation at both the individual and group level. Despite the success of personality research in social organisms generally, and social Hymenoptera in particular, social wasps (Vespidae) have received little to no attention in the personality literature. In the present study, we testPolistes metricus(Vespidae; Polistinae) paper wasp queens for the presence of repeatable variation in, and correlations (“behavioral syndromes”) between, several commonly used personality metrics: boldness, aggressiveness, exploration, and activity. Our results indicate thatP. metricusqueens exhibit personalities for all measured traits and correlations between different behavioral measures. Given that paper wasps have served as a model organism for a wide range of phenomena such as kin selection, dominance hierarchies, mate choice, facial recognition, social parasitism, and chemical recognition, we hope that our results will motivate researchers to explore whether, or to what degree, queen personality is important in their research programs.

关键词：症候群个性行为有机体度量标准配偶选择面部识别化学识别

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Artificial Neural Network for Combining Forecasts

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Journal of Systems Engineering and Electronics 1995年第2期6卷 58-64页

作者： Shanming Shi, Li D. Xu & Bao Liu(Department of Computer Science, University of Colorado at Boulder, Boulder, CO 80309, USA)(Department of MSIS, wright State University, Dayton, OH 45435,USA)(Institute of Systems Engineering, Tianjin University, Tianjin 30 Department of Computer Science University of Colorado at Boulder CO 80309 USA Department of MSIS Wright State University Dayton OH 45435 USA Institute of Systems Engineering Tianjin University Tianjin 300072 China

This paper proposes artificial neural networks (ann) as a tool for nonlinear combination of forecasts. In this study, three forecasting models are used for individual forecasts, and then two linear combining methods are used to compare with the ann combining method. The comparative experiment using real--world data shows that the prediction by the ann method outperforms those by linear combining methods. The paper suggests that the ann combining method can be used as- an alternative to conventional linear combining methods to achieve greater forecasting accuracy.

关键词： Artificial neural network,Forecasting Combined forecasts Nonlinear systems.

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Meeting report:a hard look at the state of enamel research

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International Journal of Oral Science 2017年第4期9卷 193-199页

作者： ophir d klein olivier duverger wendy shaw rodrigo s lacruz derk joester janet moradian-oldak megan k pugach j timothy wright sarah e millar ashok b kulkarni john d bartlett thomas gh diekwisch pamela den besten james p simmer program in craniofacial biology and department of orofacial sciences university of californiasan franciscoSan FranciscoUSA department of pediatrics and institute for human genetics university of californiasan franciscoSan FranciscoUSA laboratory of skin biology national institute of arthritis and muscular and skin diseasesnational institutes of healthBethesdaUSA physical science division pacific northwest national laboratoriesRichlandUSA department of basic science and craniofacial biology new york university college of dentistryNewYorkUSA department of materials science and engineering northwestern universityevanstonusaEvanstonUSA center for craniofacial molecular biology herman ostrow school of dentistryuniversity of southern californiaLos AngelesUSA the forsyth institute CambridgeUSA department of developmental biology harvard school of dental medicineBostonUSA department of pediatric dentistry university of north caroline school of dentistryChapel HillUSA departments of dermatology and cel&developmental biology perelman school of medicineand department of anatomy&cell biologyschool of dental medicineuniversity of pennsylvaniaPhiladelphiaUSA functional genomics section national institute of dental and craniofacial researchBethesdaUSA division of biosciences ohio state universitycollege of dentistryColumbusUSA department of periodontics and center for craniofacial research and diagnosis texas a&m university college of dentistryDallasUSA center for children’s oral health research and department of orofacial sciences university of californiasan franciscoSan FranciscoUSA biologic and materials sciences and division of prosthodontics university of michiganAnn ArborUSA

The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines （ENAMEL） Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National institute of Dental and Craniofacial Research （NIDCR）. Discussion topics included model organisms, stem cells/cell lines, and tissues/3D cell culture/organoids. Scientists from a number of disciplines, representing institutions from across the United States, gathered to discuss advances in our understanding of enamel, as well as future directions for the field.

关键词： enamel mineralized tissue mineralization ameloblast stem cell

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美的构造——米兰设计周Structure挪威当代工艺设计展

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现代装饰（家居） 2016年第5期 76-84页

作者： Andreas Engesvik Anette Krogstad Anja Borgersrud ann Kristin Einarsen Aron Irving-Li Barmen & Brekke Bjrn van den Berg Falke Svatun & Christina Peel Elin Hedberg Falke Svatun günzler.polmar Kiyoshi Yamamoto Kneip Kristin Opem Kristine Bjaadal Lars Beller Fjetland Marianne Andersen Martin Solem Millie Behrens Noidoi Runa Klock Sara Skotte Sara wright Polmar Sverre Uhnger Thomas Jenkins Vera & Kyte 范嘉苑

今年的米兰设计周迎来了一个全新的展览——＂Structure＂,该展览由挪威的Klubben设计师联盟、全球知名涂料制造商Jotun公司以及挪威设计与建筑中心共同主办,展览于4月12日至17日首次亮相于米兰设计周Ventura Lambrate展区。此次展览展... 详细信息

今年的米兰设计周迎来了一个全新的展览——＂Structure＂,该展览由挪威的Klubben设计师联盟、全球知名涂料制造商Jotun公司以及挪威设计与建筑中心共同主办,展览于4月12日至17日首次亮相于米兰设计周Ventura Lambrate展区。此次展览展出了26位优秀的挪威设计师的作品,其中包括家具、灯具、陶瓷品、纺织品以及空间饰品等,旨在展示挪威的当代工艺设计,让观众了解挪威当代设计的创新理念与独到魅力。

关键词： Structure 工艺设计涂料制造商设计原型日至层次感策展人室内设计家居设计视觉冲击

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