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Bidirectional link between diabetes mellitus and coronavirus disease 2019 leading to cardiovascular disease:A narrative review

引用

World Journal of diabetes 2021年第3期12卷 215-237页

作者： Vijay Viswanathan Anudeep Puvvula ankush d jamthikar Luca Saba Amer M Johri Vasilios Kotsis Narendra N Khanna Surinder K dhanjil Misha Majhail durga Prasanna Misra Vikas Agarwal George d Kitas Aditya M Sharma Raghu Kolluri Subbaram Naidu Jasjit S Suri M Viswanathan Hospital for diabetes M Viswanathan Diabetes Research CentreChennai 600013India Annu’s Hospitals for Skin and diabetes Nellore 524101Andhra PradeshIndia department of Electronics and Communications Visvesvaraya National Institute of TechnologyNagpur 440010MaharashtraIndia department of Radiology University of CagliariMonserrato 09045CagliariItaly department of Medicine Division of CardiologyQueen’s UniversityKingstonON K7L 3N6Canada 3rd department of Internal Medicine Hypertension CenterPapageorgiou HospitalAristotle University of ThessalonikiThessaloniki 541-24Greece department of Cardiology Indraprastha APOLLO HospitalsNew Delhi 110020India Stroke diagnosis and Monitoring division AtheroPoint™LLCCA 95661United States Stroke diagnosis and Monitoring division AtheroPoint™RosevilleCA 95661United States department of Clinical Immunology and Rheumatology Sanjay Gandhi Postgraduate Institute of Medical SciencesLucknow 226014Uttar PradeshIndia departments of Medicine Sanjay Gandhi Postgraduate Institute of Medical SciencesLucknow 226014Uttar PradeshIndia Academic Affairs Dudley Group NHS Foundation TrustDudley DY12HQUnited Kingdom Arthritis Research UK Epidemiology Unit Manchester UniversityManchester M139PLUnited Kingdom division of Cardiovascular Medicine University of VirginiaCharlottesvilleVA 22908United States OhioHealth Heart and Vascular OhioOH 43082United States Electrical Engineering department University of MinnesotaDuluthMN 55812United States

Coronavirus disease 2019(COVId-19)is a global pandemic where several comorbidities have been shown to have a significant effect on *** with diabetes mellitus(dM)have a higher mortality rate than non-dM patients if they get *** studies have indicated that patients with a history of diabetes can increase the risk of severe acute respiratory syndrome coronavirus 2 ***,patients without any history of diabetes can acquire newonset dM when infected with ***,there is a need to explore the bidirectional link between these two conditions,confirming the vicious loop between“dM/COVId-19”.This narrative review presents(1)the bidirectional association between the dM and COVId-19,(2)the manifestations of the dM/COVId-19 loop leading to cardiovascular disease,(3)an understanding of primary and secondary factors that influence mortality due to the dM/COVId-19 loop,(4)the role of vitamin-d in dM patients during COVId-19,and finally,(5)the monitoring tools for tracking atherosclerosis burden in dM patients during COVId-19 and“COVId-triggered dM”*** conclude that the bidirectional nature of dM/COVId-19 causes acceleration towards cardiovascular *** to this alarming condition,early monitoring of atherosclerotic burden is required in“diabetes patients during COVId-19”or“new-onset diabetes triggered by COVId-19 in Non-diabetes patients”.

关键词： COVId-19 diabetes mellitus Bidirectional association Cardiovascular disease Atherosclerotic burden Imaging tools

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