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Effects of Sialic Acid from Edible Bird Nest on Cell Viability Associated with Brain Cognitive Performance in Mice

World Journal of Traditional Chinese Medicine 2019年第4期5卷 214-219页

作者： Siti Khadijah abdul Khalid Aswir Abd Rashed Saleha abdul aziz Hafandi Ahmad Departments of Veterinary Preclinical Sciences Faculty of Veterinary MedicineUniversiti Putra MalaysiaSerdangSelangor Departments of Veterinary Pathology and Microbiology Faculty of Veterinary MedicineUniversiti Putra MalaysiaSerdangSelangor Department of Nutrition Metabolic and Cardiovascular ResearchInstitute for Medical ResearchJalan PahangKuala LumpurMalaysia

Background:Edible bird nest(EBN)is a natural food product rich in glycoprotein such as sialic acid,which has been reported to improve brain *** EBN is widely consumed due to its higher nutritional contents and antioxidant status;however,an interaction of EBN on brain cell metabolic activity and viability are still ***:The objectives of this study were to identify the effect of sialic acid from EBN on the cell viability and to determine the appropriate concentration of sialic acid on cognitive performance in *** and Methods:The viability of pheochromocytoma and neuroblastoma cell lines were tested using the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide *** in vivo study,7-week-old female BALB/c mice were randomly assigned into four treatment groups and were treated with sialic acid for 21 *** day 22,all mice were tested on cognitive performance by Y-maze ***:Treatment concentration of sialic acid extract and sialic acid standard at 60μg/mL(0.6 ppm)increased cell viability and showed no cytotoxicity effects in pheochromocytoma and neuroblastoma cell *** addition,an administration of higher dose of sialic acid at 0.6 ppm in animals improved Y-maze test performance,which they showed significantly higher number of entries and time spent in the novel ***:Thus,the current study shows that the sialic acid extract at 0.6 ppm improved brain cognitive performance in mice associated with an increased viability of pheochromocytoma and neuroblastoma cell lines.

关键词： Cell viability cognitive function edible bird nest mice sialic acid

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ON THE COEFFICIENTS OF A POLYNOMIAL WITH RESTRICTED ZEROS

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Analysis in Theory and Applications 2009年第2期25卷 142-146页

作者： abdul aziz W. M. Shah Post Graduate Department of Mathematics University of Kashmir Srinagar India Post Graduate Department of Mathematics Govt.College BaramullaKashmir-193101 India

Let P（z）=anz^n＋an-1z^n-1＋…＋a0be a complex polynomial of degree n. There is a close connection between the coefficients and the zeros of P（z）. In this paper we prove some sharp inequalities concerning the coefficients of the polynomial P（z） with restricted zeros. We also establish a sufficient condition for the separation of zeros of P（z）.

关键词： polynomial inequality coefficient estimate separation of zeros

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Prevalence and associated factors of depression,anxiety and stress among coronavirus disease 2019(COVID-19)patients in Herat,Afghanistan

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Global Health Journal 2022年第2期6卷 85-90页

作者： aziz-ur-Rahman Niazi Mina Alekozay abdul Fattah Najm Department of Public Health and Infectious Diseases Faculty of MedicineHerat UniversityHeratAfghanistan International Assistance Mission HeratAfghanistan

Objectives:Coronavirus disease 2019(COVID-19)pandemic has been associated with a great level of psychological distresses in people around the *** study aims to assess the prevalence of depression,anxiety and stress among COVID-19 patients and identify the associated factors,in Herat Province of ***:This cross-sectional study was conducted on 459 hospitalized patients between May and September *** was collected with a structured questionnaire on depression,anxiety and stress scale,which was the validated ***-square test was adopted to analyze the associations of the prevalence of the mental disorders and the ***:The mean age of participants was 38.05;51.9%(238/459)were male and 84.1%(386/459)were *** scores for depression,anxiety and stress were 5.0,8.0,and 10.0,***,general health condition,nutritional status,COVID-19 clinical manifestation and concurrent comorbidities(except diabetes and hypertension)were significantly associated with mental disorders;while association between marital status and these psychological disorders was not ***,a significant difference was observed in the level of anxiety between healthcare workers and other ***:This is the first study to report the high prevalence of depression,anxiety and stress among COVID-19 patients in Herat,which indicates the negative effect of mental health for COVID-19 patients globally and highlights the need for urgent and appropriate interventions to improve mental health of people during the pandemic.

关键词： Depression Anxiety Stress Coronavirus disease 2019(COVID-19) Herat Afghanistan

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Spatial characteristics of defensive traditional architecture in multiethnic village of Guangxi:Case studies of Mozhuang Village and Guxietun Village

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Frontiers of Architectural Research 2023年第4期12卷 683-699页

作者： Siyi Jia Mohd Hafizal Bin Mohd Isa Zalena Binti abdul aziz School of Housing Building and PlanningUniversiti Sains MalaysiaPenang 11800Malaysia

Defensive traditional architecture research is critical to the understanding of the ethnic history and multiethnic ***,there are few studies on the combination of traditional architecture and multiethnicity,and most of the defensive traditional buildings in multiethnic villages of Guangxi are facing the plight of being destroyed and *** aim of this research is to identify the spatial characteristics,commonalities,and differences of Guangxi’s defensive traditional architecture with Mozhuang Village and Guxietun Village as the examples,in order to preserve the architectural and ethnic components of these *** research uses the four research methods:literature review,field research,observation and space syntax analysis,and it summarizes the three results from the five aspects:plan,elevation,construction material,masonry and *** showed that the spatial characteristics are dominated by the ethnic group with the higher technological,cultural or economic level,and there are both commonalities and differences in defensive traditional architecture in multiethnic *** on the three study results,this research proposes some overall suggestions toward traditional villages and architecture improvement in ethnic areas.

关键词： Defensive traditional architecture Spatial characteristics Multiethnic village Commonalities and differences Development

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Structural,electrical,dielectric and magnetic properties of Mn-Nd substituted CoFeO3 nano sized multiferroics

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Progress in Natural Science:Materials International 2016年第4期26卷 325-333页

作者： abdul aziz E.Ahmed Muhammad Naeem Ashiq Muhammad Azhar Khan Nazia Karamat Irshad Ali Department of Physics Bahauddin Zakariya University Institute of Chemical Sciences Bahauddin Zakariya University Department of Physics The Islamia University of Bahawalpur Institute of Chemical Sciences Bahauddin Zakariya University

A series of Mn x Co1-xFe1-yNdyO3（where x=0.0–1.0 & y=0.0–0.1） multiferroic nanocrystals was synthesized via sol-gel auto-combustion technique. The structure was confirmed by X-ray diffraction（XRD）while morphology was investigated by scanning electron microscopy（SEM）. The electrical resistivity was observed to increase from 2.14 * 10～7 to 8.77 * 10～9 Ω-cm and activation energy was found to increase from 0.64 to 0.75 e V, while the drift mobility decreased from 4.75 * 10-13to 1.27 * 10-15cm2V-1S-1by the substitution of Mn and Nd contents. The dielectric constant, dielectric loss and dielectric loss factor decrease with frequency and Mn-Nd contents. The saturation magnetization was increased from 34 to 70 emu g-1while the coercivity decreased from 705 to 262 Oe with the increase of *** increase in electrical resistivity and saturation magnetization while decrease in dielectric parameters and coercivity make these nanomaterials suitable for applications in microwave devices and longitudinal magnetic recording media.

关键词： Nanostructured materials XRD Dielectric properties Electrical properties Magnetic properties

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A Hybrid Deep Learning-Based Unsupervised Anomaly Detection in High Dimensional Data

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Computers, Materials & Continua 2022年第3期70卷 5363-5381页

作者： Amgad Muneer Shakirah Mohd Taib Suliman Mohamed Fati abdullateef O.Balogun Izzatdin abdul aziz Department of Computer and Information Sciences Universiti Teknologi PETRONASSeri Iskandar32160Malaysia Centre for Research in Data Science(CERDAS) Universiti Teknologi PETRONASSeri Iskandar32610PerakMalaysia Information Systems Department Prince Sultan UniversityRiyadh11586Saudi Arabia

Anomaly detection in high dimensional data is a critical research issue with serious implication in the real-world *** issues in this field still unsolved,so several modern anomaly detection methods struggle to maintain adequate accuracy due to the highly descriptive nature of big *** a phenomenon is referred to as the“curse of dimensionality”that affects traditional techniques in terms of both accuracy and ***,this research proposed a hybrid model based on Deep Autoencoder Neural Network(DANN)with five layers to reduce the difference between the input and *** proposed model was applied to a real-world gas turbine(GT)dataset that contains 87620 columns and 56 *** the experiment,two issues have been investigated and solved to enhance the *** first is the dataset class imbalance,which solved using SMOTE *** second issue is the poor performance,which can be solved using one of the optimization *** optimization algorithms have been investigated and tested,including stochastic gradient descent(SGD),RMSprop,Adam and ***,Adamax optimization algorithm showed the best results when employed to train *** experimental results show that our proposed model can detect the anomalies by efficiently reducing the high dimensionality of dataset with accuracy of 99.40%,F1-score of 0.9649,Area Under the Curve(AUC)rate of 0.9649,and a minimal loss function during the hybrid model training.

关键词： Anomaly detection outlier detection unsupervised learning autoencoder deep learning hybrid model

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Predicting the distribution of the Asian tapir in Peninsular Malaysia using maximum entropy modeling

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Integrative Zoology 2012年第4期7卷 400-406页

作者： Gopalasamy Reuben CLEMENTS D.Mark RAYAN Sheema abdul aziz Kae KAWANISHI Carl TRAEHOLT David MAGINTAN Muhammad Fadlli abdul YAZI Reid TINGLEY Center for Tropical Environmental and Sustainability Science and School of Marine and Tropical Biology James Cook UniversityCairnsAustralia Center for Malaysian Indigenous Studies University of MalayaKuala LumpurMalaysia WWF Malaysia Petaling JayaMalaysia Durrell Institute of Conservation and Ecology University of KentCanterburyUK Malaysian Conservation Alliance for Tigers(MYCAT)Secretariat's Office Petaling JayaMalaysia Copenhagen Zoo CopenhagenDenmark Department of Wldife and National Parks Peninsular Malaysia Kuala LumpurMalaysia School of Biological Sciences University of SydneySydneyAustralia

In 2008,the IUCN threat status of the Asian tapir(Tapirus indicus)was reclasified from‘vulnerable'to‘en-dangered'.The latest distribution map from the IUCN Red List suggests that the tapirs'native range is becom-ing increasingly fragmented in Peninsular Malaysia,but distribution data collected by local researchers sug-gest a more extensive geographical ***,we compile a database of 1261 tapir occurrence records within Peninsular Malaysia,and demonstrate that this species,indeed,has a much broader geographical range than the IUCN range map ***,extreme spatial and temporal bias in these records limits their utility for conservation ***,we used maximum entropy(MaxEnt)modeling to elucidate the potential ex-tent of the Asian tapir's occurrence in Peninsular Malaysia while accounting for bias in existing distribution *** MaxEnt model predicted that the Asian tapir has a wider geographic range than our fine-scale data and the IUCN range map both *** 37%of Peninsular Malaysia contains potentially suit-able tapir *** results justify a revision to the Asian tapir's extent of occurrence in the IUCN Red ***,our modeling demonstrated that selectively logged forests encompass 45%of potentially suitable tapir habitats,underscoring the importance of these habitats for the conservation of this species in Peninsular Malaysia.

关键词： ecological niche IUCN Malayan tapir mammal MaxEnt species distribution model

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掺Ni钒磷氧化物催化剂的合成和表征

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催化学报 2007年第12期28卷 1037-1040页

作者： TAUFIQ-YAP Yun Hin abdul GHANI abdul aziz 博特拉大学科学院化学系博特拉科学和技术实验室

以VOPO4.2H2O为原料制备了钒磷氧化物催化剂,考察了镍掺杂(1%,2%和5%)对该催化剂的影响.低掺杂量的Ni明显提高了活性晶格氧物种O-的数量,降低了V5+和V4+相的还原峰温.粉末X射线衍射、程序升温还原和化学分析结果表明,高掺杂量的Ni促使V5... 详细信息

以VOPO4.2H2O为原料制备了钒磷氧化物催化剂,考察了镍掺杂(1%,2%和5%)对该催化剂的影响.低掺杂量的Ni明显提高了活性晶格氧物种O-的数量,降低了V5+和V4+相的还原峰温.粉末X射线衍射、程序升温还原和化学分析结果表明,高掺杂量的Ni促使V5+物相生成并抑制V4+物相出现.高含量与V5+相关的氧物种会降低正丁烷的转化率,但会提高马来酸酐的选择性.

关键词：焦磷酸钒酰镍正丁烷氧化马来酸酐

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Helicobacter pylori infection and gastropathy:A comparison between Indonesian and Japanese patients

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World Journal of Gastroenterology 2009年第39期15卷 4928-4931页

作者： Murdani abdullah Hiroyuki Ohtsuka abdul aziz Rani Tadashi Sato Ari F Syam Masayuki A Fujino Division of Gastroenterology Department of Internal MedicineFaculty of Medicine University of IndonesiaCipto Mangunkusumo Hospital First Department of Medicine Yamanashi Medical University

AIM： To compare the effects of He/icobacter py/ori （Hpylon） infection on gastropathy between Indonesian and Japanese patients. METHODS： Biopsy specimens were obtained during upper gastrointestinal endoscopy from 167 subjects （125 Indonesians and 42 Japanese） with uninvestigated symptoms of dyspepsia. The specimens were analyzed for the presence of H pylori using urease analysis, histopathology, and cell culture. The grade and activity of gastritis was assessed using the updated Sydney system. RESULTS： The percentages of Indonesian and Japanese patients who were H py/ori-positive at the antrum or body of the stomach were similar （68% and 59.5%, respectively; P = 0.316）. Of those who were Hpylori-positive, more Japanese patients than Indonesian patients had high levels of polymorphonuclear cells （P = 0.001）, mononuclear cells （P = 0.013）, glandular atrophy （P = 0.000）, and intestinal metaplasia （P = 0.011） in both the antrum and body of the stomach. CONCLUSION： The grade of gastritis and prevalence of mucosal atrophy and intestinal metaplasia were higher in Japanese patients. The difference between Indonesian and Japanese patients was significant.

关键词： Helicobacterpylori Gastritis Gastric cancer Intestinal metaplasia Atrophy

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XPC Lys939Gln polymorphism, smoking and risk of sporadic colorectal cancer among Malaysians

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World Journal of Gastroenterology 2013年第23期19卷 3623-3628页

作者： abdul aziz Ahmad Aizat Mohd Shahpudin Siti Nurfatimah Mustapha Mohd Aminudin Ravindran Ankathil Human Genome Centre School of Medical SciencesUniversiti Sains Malaysia Health Campus16150 Kubang Kerian Kelantan Malaysia

AIM: To investigate the risk association of xeroderma pigmentosum group C (XPC ) Lys939Gln polymorphism alone and in combination with cigarette smoking on colorectal cancer (CRC) predisposition. METHODS: Peripheral blood samples of 510 study subjects (255 CRC patients, 255 controls)were collected. DNA was extracted and genotyping was performed using polymerase chain reaction-restriction fragment length polymorphism. The association between polymorphic genotype and CRC predisposition was determined using the OR and 95%CI. RESULTS: The frequency of the homozygous variant (Gln/Gln) genotype was significantly higher in cases compared with controls (16.0% vs 10.2%, P = 0.049). The Gln/Gln genotype of XPC showed a significantly higher association with the risk of CRC (OR = 1.884; 95%CI: 1.082-3.277; P = 0.025). In the case of allele frequencies, variant allele C was associated with a significantly increased risk of CRC (OR = 1.375; 95%CI: 1.050-1.802; P = 0.020). Moreover, the risk was markedly higher for those who were carriers of the Gln/Gln variant genotype and were also cigarette smokers (OR = 3.409; 95%CI: 1.061-10.949; P = 0.032). CONCLUSION: The XPC Gln/Gln genotype alone and in combination with smoking increases the risk of CRC among Malaysians.

关键词： DNA repair Xeroderma pigmentosum group C Lys939Gln polymorphism Cigarette smoking Colorectal cancer Susceptibility risk

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