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Metabolic evaluation of first-time uncomplicated renal stone formers:A prospective study

Current Urology 2023年第1期17卷 36-40页

作者： Satish Kumar Ranjan Ankur Mittal anissa atif mirza Sunil Kumar Vikas Kumar Panwar Shivcharan Navriya Arup Kumar Mandal Kim Jacob Mammen Department of Urology AIIMSRishikeshIndia Department of Biochemistry AIIMSRishikeshIndia Department of Urology Himalayan Institute of Medical SciencesJolly GrantDehradun248016India

Background:Nephrolithiasis is a global health *** recurrence rate after the first stone clearance is approximately 50%at 5 *** abnormalities are an important factor responsible for stone *** prevalidated study aimed to evaluate metabolic abnormalities associated with first-time uncomplicated renal stone formers(FTURSF).Materials and methods:In this prospective,exploratory,time-bound,descriptive study,30 first-time renal stone formers were evaluated for metabolic ***-risk stone formers were excluded from the *** were collected in a predefined proforma,transferred to an Excel sheet,and analyzed using the Statistical Package for Social Sciences 20 and Epi Info *** exact test,Mann-Whitney U test,paired t test,and Pearson correlation coefficient were used for statistical ***:The mean age of the participants was 35.57±11.07 years,with a male-to-female ratio of *** most common abnormality was a 24-hour urine volume of<2.5 L in 73.33%of the *** or more metabolic abnormalities were detected in 76.67%of the *** common metabolic abnormalities detected were hypocitraturia(60%),hypercalciuria(16.67%),hyperoxaluria(13.33%),and hyperuricosuria(3.33%).Parathyroid adenoma was detected in one participant(3.33%).Conclusions:Our study documented significant metabolic abnormalities in ***,a simplified metabolic evaluation protocol should be adopted while evaluating *** of an underlying metabolic abnormality would enable the early institution of preventive measures to reduce stone recurrence and related complications.

关键词： Renal stone disease First-time renal stone former Metabolic abnormalities

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