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Hematochezia Revealing an Adenocacinoma

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Open Journal of Pediatrics 2023年第3期13卷 428-431页

作者： Amal Hamami Madiha Benhachem Ayad Ghannam Aziza El Ouali Abdeladim Babakhouya Noura seghrouchni Nassira Karich Amal Bennani Maria Rkain Department of Pediatrics Faculty of Medicine and Pharmacy of Oujda Mohammed First University Oujda Morocco Laboratory of Pathological Anatomy Faculty of Medicine and Pharmacy of Oujda Mohammed First University Oujda Morocco

Colorectal carcinoma (CRC) is a common pathology in the adult population but remains a very rare neoplasia in childhood with delayed diagnosis and advanced stage with grim prognosis that can be fatal, research regarding pediatric adenocarcinoma remain very rare. IT represents approximately 1% of pediatric neoplasms. It is usually associated with predisposing genetic factors;this pathology is closely linked with the inheritance of familial syndromes. The pediatric clinical presentations are nonspecific, with a grim prognosis. This review aimed to report a case of a 10-year-old girl who presented with constipation and hematochezia evolving since three months’ diagnosis with rectal adenocarcinoma.

关键词： Adenocarcinoma Colorectal Cancer Rare Child Grim Prognosis

Does Obesity Affect Early Results after Coronary Artery Bypass Grafting?

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World Journal of Cardiovascular Surgery 2017年第10期7卷 119-129页

作者： Mahdi Aithoussa Noureddine Atmani Anis seghrouchni Abdessamad Abdou Younes Moutakiallah Mehdi Bamous Siham Bellouize Fouad Nya Zouhair Lakhal Abdedaim Hatim Ghadbane Youssef Elbekkali Abdelatif Boulahya Department of Cardiovascular Surgery Mohammed V Military Teaching Hospital Mohammed V University Souissi Rabat Morocco Department of Cardiology Mohammed V Military Teaching Hospital Mohammed V University Souissi Rabat Morocco

Background: The aim of this study was to quantify the effect of obesity on early results after coronary artery bypass grafting (CABG). Methods: A retrospective cohort study of patients underwent isolated CABG from January 2000 through December 2012 was conducted. 586 patients were classified into two groups: Obese (n = 100) BMI ≥ 30 kg/m2 and non-obese (n = 486) BMI ≤ 30kg/m2. Results: The obese patients included more women (p 0.01), hypertensives (p = 0.01) and dyslipidemics (p = 0001). The CPB, aortic champ times and number of bypass graft were similar between the groups (p = 0.35, p = 0.51 and p = 0.59 respectively). Also the composite of in-hospital mortality and postoperative complication didn’t differ between the groups. The incidence of perioperative myocardial infarction, and need for inotropic drugs or IABP were significantly less in obese patients (p = 0.028, p = 0.031 and p 0.01 respectively). Conclusions: The current study showed that obesity is not a risk factor of adverse events after CABG and continuous to give another aspect of the “obesity paradox”.

关键词： Obesity Coronary Artery Bypass Grafting Morbidity Mortality

Mitral Valve Commissurotomy: Which One between the Three Techniques Gives a Better Long-Team Outcome?

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World Journal of Cardiovascular Diseases 2017年第2期7卷 37-45页

作者： Mahdi Aithoussa Noureddine Atmani Ayoub Abetti Mehdi Bamous Abdessamad Abdou Younes Moutakiallah Anis seghrouchni Fouad Nya Siham Bellouize Mohamed Drissi Ilyas Asfalou Abdelatif Boulahya Department of Cardiac Surgery Mohamed V Military Hospital Mohammed V University Rabat Morocco Department of Cardiology Mohamed V Military Hospital Mohammed V University Rabat Morocco

Objective: we sought to compare long-term results of three techniques: CMC, OMC and PMC in patients with rheumatic mitral stenosis. Patients and Method: Between January 1994 and December 2015, 183 patients underwent mitral valve surgery for rheumatic mitral restenosis. All patients were investigated by echocardiography-Doppler performed by a senior cardiologist. The patients were divided into 3 groups: patients who have previously closed mitral commissurotomy (CMC n = 101), patients with previously open mitral commissurotomy (OMC n = 28) and those treated by Balloon mitral valvuloplasty (PMC = 54). Results: The three groups were comparable in term of major demographic data. Mitral restenosis occurred precociously in groups treated by PMC (7 ± 4 years), followed by group with OMC 11.4 ± 4 years and CMC group but it occurred later CMC 16.8 ± 7.8 years (p Conclusion: CMC produces better long-term outcome than OMC and PMC. However, it would be premature to conclude to its superiority.

关键词： Rheumatic Mitral Stenosis Closed Mitral Commissurtomy Open Mitral Commissurotomy Balloon Mitral Valvuloplasty

Does Right Coronary Artery Stenosis Increase Morbi-Mortality in Patients Undergoing Coronary Artery Bypass Graft for Left Main Coronary Artery Disease?

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World Journal of Cardiovascular Diseases 2015年第12期5卷 397-404页

作者： M. Aithoussa A. Abdou N. Atmani M. Bamous Y. Moutakiallah F. Nya A. seghrouchni A. Hatim Y. Elbekkali A. Boulahya Cardiac Surgery Department Mohammed V Military Hospital Mohammed V University Hay Riad Rabat Morocco

Background: The association of right coronary artery (RCA) stenosis in patients undergoing myocardial revascularization for left main coronary artery (LMCA) stenosis affects the prognosis. This study aimed to compare immediate results of patients with isolated LMCA stenosis and those with combined RCA stenosis. Patients and methods: We retrospectively evaluated 107 consecutive patients with LMCA disease who underwent coronary artery bypass grafts. The patients were divided into two groups: isolated LMCA stenosis (n = 36) and LMCA stenosis + RCA stenosis (n = 71). Different variables (preoperative, intra operative and post operative) were compared. Results: Patients with LMCA stenosis + RCA stenosis experienced higher prevalence of diabetes mellitus (p = 0.024) and smoker (p = 0.032). Also left ventricular EF was reduced (p = 0.004). Myocardial revascularization was more complete in patients with LMCA stenosis + RCA stenosis (p = 0.033), but in-hospital mortality rate was higher (12.6% vs 5.5%) in isolated LLMCA stenosis, but it did not reach statistical significance (p = 0.32). Except low output syndrome (LOS) that was frequent in presence of RCA stenosis (p = 0.026), no significant difference was found between groups for other complications. Conclusion: The presence of RCA stenosis in patients undergoing CABG for LMCA disease increases 30 day mortality but without significant impact on overall morbidities.

关键词： Left Main Coronary Artery (LMCA) Stenosis Left Main Coronary Artery and Right Coronary Artery Stenosis Coronary Artery Bypass Graft (CABG) Immediate Results

Surgery in the Acute Phase of Infective Endocarditis: 5 Years after Our Initial Experience

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World Journal of Cardiovascular Diseases 2016年第8期6卷 275-284页

作者： Youssef El Bekkali Noureddine Atmani Siham Bellouize Mohamed Drissi Younes Moutakiallah Mehdi Bamous Abdessamad Abdou Fouad Nya Anis seghrouchni Mahdi Aithoussa Brahim Amahzoune Abdedaim Hatim Ghadbane Abdelatif Boulahya Cardiac Surgery Department Mohammed V Military Hospital Rabat Morocco Reanimation of Cardiac Surgery Department Mohamed V Medical Faculty Rabat Morocco

Aim: Comparing the results of acute phase infectious endocarditis surgery between two periods. Methods and Results: The study is about 2 series, series A between 1993 and 1997, and series B between 1998 and 2012, respectively 13 and 51 patients. The two periods were similar concerning the number of patients per year, which was 3.12 cases/year for series A and 3.64 cases/year for series B. The authors noted a change in epidemiological profile, with an increase of median age (31 y.o for series A and 37 y.o for series B), and the emergency of endocarditis on prosthetic valve (none on series A and 8 cases for series B). Surgical indications and results didn’t change too much, hospital mortality rate was 15.3% for series A and 17.6% for series B. Conclusion: Infectious endocarditis is still a major public healthcare problem in developing countries, despite the development of diagnostic tools and patient care. Prevention is still the major asset in the treatment of this disease.

关键词： Infectious Endocarditis Acute Phase Surgery

Redo Cardiac Surgery: Bleeding Control

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World Journal of Cardiovascular Diseases 2017年第9期7卷 299-307页

作者： A. seghrouchni M. Bamous Y. Moutakiallah F. Nya N. Atmani A. Abdou M. Belkhadir S. Bellouize A. Abetti R. Mounir A. Moujahid A. G. Hatim M. Drissi Y. El Bekkali A. Boulahya M. Ait. Houssa Cardiac Surgery Department Mohammed V Military Hospital Mohammed V University Rabat Morocco

Redo cardiac surgery increases?mortality and morbidity. The aim of this study was to determine if aprotinin was superior to tranexamic acid concerning control bleeding loss after redo valve surgery. A retrospective study was conducted from January 1994 until December 2014. 221 patients underwent redo cardiac valve surgery and separated into two groups: aprotinin group (n?=?85) and tranexamic acid group (n?=?136). Univariate tests were applied for data analysis. A total of 221 patients were enrolled in this study. This cohort was separated into two groups: aprotinin group (n?=?85) and tranexamic acid group (n?=?136). Euroscore in tranexamic acid group was higher: 5.96 ± 3.04 vs.?5.17 ± 2.83 in aprotinin group?(p?=?0.055). There was no statistical difference in postoperative mortality between the two groups (p?= 0.153). No statistical differences were reported concerning: total blood loss (p?= 0.51), red blood cells transfusion (p?= 0.215), reexploration for bleeding (p?= 0.537) and postoperative renal failure (p?= 0.79). There were statistical differences concerning mechanical ventilation time, which is longer in tranexamic acid group (p?= 0.008) and the use of inotropic drug support, which is more frequent in the tranexamic acid group (p?= 0.001). Our results demonstrated that tranexamic acid and aprotinin reduce transfusion requirement and blood loss. Due to financial reason, we chose tranexamic acid in preventing blood loss in redo valve surgery.

关键词： Cardiac Surgery Aprotinin Tranexamic Acid Cardiopulmonary Bypass