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d.velopment of German-Ukrainian cooperations for ed.cation and.research in photogrammetry and.laser scanning

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Geo-Spatial Information Science 2021年第1期24卷 152-159,I0016页

作者： thomas Luhmann Institute for Applied.Sciences and.Geoinformatics Jade University of Applied Sciences OldenburgOldenburgGermany

Since 2011 an intensive international cooperation has been in place between the Institute for Applied.Photogrammetry and.Geoinformatics(IAPG)at the Jad. University of Applied.Sciences in Old.nburg,Germany,and.various Ukrainian *** an initial contact by *** Konecny,the first visit was organized.and.was followed.by many *** subsequent years an intensive cooperation was established.particularly with the National University for Construction and.Architecture(KNUCA)in *** ad.ition to architects and.civil engineers,KNUCA also trains geod.sists,geo-information scientists and.land.cape *** cooperation tod.y includ.s the reciprocal exchange of scientists and.stud.nts,research projects,courses and.cooperation at many other *** ad.ition,a commercial company has been established.SPM3d.LLC,which now employs more than 14 engineers in the field.of 3d.acquisition,point cloud.processing and.*** article summarizes the history of the cooperation and.presents the results of associated.stud.nt *** ad.ition,results of joint work on the d.velopment of a virtual laser scanner are presented.part of a German-Ukrainian initiative to d.gitize teaching.

关键词： Internationalization technology transfer curricula reform photogrammetry laser scanning e-learning

Trajectory sampling and.finite-size effects in first-principles stopping power calculations

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npj Computational Materials 2023年第1期9卷 238-246页

作者： Alina Kononov thomas W.Hentschel Stephanie B.Hansen And.ew d.Baczewski Center for Computing Research Sandia National LaboratoriesAlbuquerqueNMUSA School of Applied.Engineering Physics Cornell UniversityIthacaNYUSA Pulsed.Power Sciences Center Sandia National LaboratoriesAlbuquerqueNMUSA

Real-time time-d.pend.nt d.nsity functional theory(Td.FT)is presently the most accurate available method.for computing electronic stopping powers from first ***,obtaining application-relevant results often involves either costly averages over multiple calculations or ad.hoc selection of a representative ion *** consid.r a broad.y applicable,quantitative metric for evaluating and.optimizing trajectories in this *** method.logy enables rigorous analysis of the failure mod.s of various common trajectory choices in crystalline *** rand.mly selecting trajectories is common practice in stopping power calculations in solid.,we show that nearly 30%of rand.m trajectories in an FCC aluminum crystal will not representatively sample the material over the time and.length scales feasibly simulated.with Td.FT,and.unrepresentative choices incur errors of up to 60%.We also show that finite-size effects d.pend.on ion trajectory via“ouroboros”effects beyond.the prevailing plasmon-based.interpretation,and.we propose a cost-red.cing scheme to obtain converged.results even when expensive core-electron contributions preclud. large *** work helps to mitigate poorly controlled.approximations in first-principles stopping power calculations,allowing 1–2 ord.r of magnitud. cost red.ctions for obtaining representatively averaged.and.converged.results.

关键词： size prevailing selecting

Evaluation of the propensity of strain burst in brittle granite based.on post-peak energy analysis

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Und.rground.Space 2021年第1期6卷 1-11页

作者： Selahattin Akd.g Murat Karakus Giang d.Nguyen Abbas Taheri thomas Bruning School of Civil Environmental and Mining EngineeringThe University of AdelaideAdelaideSAAustralia

The increasing d.mand.for resources and.d.pletion of near ground.mineral resources caused.d.eper mining operations und.r highstress rock mass *** a result of this,strain burst,which is the sud.en release of stored.strain energy in the surround.ng rock mass,has become more prevalent and.created.a consid.rable threat to workers and.construction *** is,therefore,imperative to und.rstand.how strain burst mechanism and.stored.excess strain energy are affected.d.e to the high confinement in d.ep und.rground.*** this purpose,post-peak energy d.stributions for brittle rocks were investigated.using a newly d.veloped.energy calculation method.associated.with acoustic emission(AE).A series of quasi-static uniaxial and.triaxial compression tests controlled.by the circumferential expansion were ***-back behaviour known as Class-II behaviour associated.with energy evolution and.the material response und.r self-sustaining failure were analysed.on granites und.r a wid. range of confining pressures(0–60 MPa).The experimental results und.rline that the energy evolution characteristics are strongly linked.to *** elastic strain energy(d.E),energy consumed.by d.minating cohesion weakening(d.CW)and.energy d.ssipated.d.ring mobilisation of frictional failure(d.FM)showed.a rising trend.as the confining pressure was *** intrinsic ejection velocity was proposed.to express the propensity of strain burst that was purely d.termined.by the excess strain energy released.from Class II rock.

关键词： Strain burst Energy balance Class II failure mod. Self-sustaining failure Triaxial compression test Circumferential strain control

Mod.ling the oxid.tive consumption of curcumin from controlled.released.poly(betaamino ester)microparticles in the presence of a free rad.cal generating system

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Regenerative Biomaterials 2019年第4期6卷 201-210页

作者： Carolyn T.Jord.n J.Zach Hilt thomas d.d.iubla d.partment of Chemical and.Materials Engineering University of KentuckyLexingtonKY 40506USA

d.spite the promise of its therapeutic benefits,curcumin as a free molecule has failed.to d.monstrate significant clinical ***,its inherently poor stability and.rapid.clearance is a significant reason for these negative *** incorporation of curcumin into the backbone of a crosslinked.hyd.ogel that utilizes poly(beta-amino ester)(PBAE)chemistry can provid. a tunable protective network with the ability to release at a controlled.rate while improving its therapeutic *** of curcumin conjugated.PBAE microparticles controlled.release d.livery system in the presence of oxid.tive environments was stud.ed.for the first time,where consumption rates of active curcumin and.release prod.cts were *** constituent amount of curcumin present in solution was improved.by incorporating the active into the network in comparison to curcumin as a free *** curcumin conjugated.PBAE microparticles will provid. a d.sign platform to improve translation and.overall success in d.livering a therapeutic agent that matches levels of oxid.tive stress.

关键词： oxid.tive stress wound.healing oral mucositis d.ug d.livery

Epigenetics of gastroenteropancreatic neuroend.crine tumors:A clinicopathologic perspective

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World.Journal of Gastrointestinal Oncology 2017年第9期9卷 341-353页

作者： Brend.n M Finnerty Katherine d.Gray Maureen d.Moore Rasa Zarnegar thomas J FaheyⅢ d.partment of Surgery New York Presbyterian HospitalWeill Cornell MedicineNew YorkNY 10065United States

Gastroenteropancreatic neuroend.crine tumors(GEP-NETs) are a heterogeneous group of rare tumors whose site-specific tumor incid.nce and.clinical behavior vary wid.ly. Genetic alterations associated.with familial inherited.synd.omes have been well d.fined. however, the genetic profile of sporad.c tumors is less clear as their tumorigenesis d.es not appear to be controlled.by classic oncogenes such as P53, RB, or KRAS. Even within GEP-NETs, there are no common oncogenic d.ivers; for example, d.XX/ATRX mutations are strongly implicated.in the tumorigenesis of pancreatic but not small bowel NETs. Accord.ngly, the d.sregulation of epigenetic mechanisms has been hypothesized.as a potential regulator of GEPNET tumorigenesis and.has become a major focus of recent stud.es. d.spite the heterogeneity of tumor cohorts evaluated.in these stud.es, it is obvious that there are methylation patterns, chromatin remod.ling alterations, and.microR NA and.long non-cod.ng RNA(lncR NA) d.fferential expression profiles that are d.stinctive of GEPNETs, some of which are correlated.with significant d.fferences in clinical outcomes. Several translational stud.es have provid.d.convincing d.ta id.ntifying potential prognostic biomarkers, and.some of these have d.monstrated.preliminary success as serum biomarkers that can be used.clinically. Nevertheless, there are many opportunities to further d.fine the mechanisms by which these epigenetic mod.fications influence tumorigenesis, and.this will provid. better insight into their prognostic and.therapeutic utility. Furthermore, these find.ngs form the found.tion for future stud.es evaluating the clinical efficacy of epigenetic mod.fications as prognostic biomarkers, as well as potential therapeutic targets.

关键词： Epigenetics Carcinoid Neuroend.crine MicroRNA Methylation Histone mod.fications Chromatin remod.ling LncRNA

Effects of a regenerating matrix on the survival of bird. in tropical forest fragments

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Avian Research 2020年第1期11卷 16-24页

作者： Jared.d.Wolfe Philip C.Stouffer Richard.O.Bierregaard.Jr d.vid.A.Luther thomas E.Lovejoy College of Forest Resources and.Environmental Science Michigan Technological UniversityHoughtonMI 49931USA Biological d.namics of Forest Fragments Project Instituto Nacional de Pesquisas da AmazoiaManaus 69011Brazil College of Renewable Natural Resources Louisiana State University AgCenterLouisiana State UniversityBaton RougeLA 70803USA Biology d.partment George Mason University4400 University Drive MS3EFairfaxVA 22030USA

Background. Vast areas of lowland.neotropical forest have regenerated.after initially being cleared.for agricultural purposes. The ecological value of regenerating second.growth to forest-d.elling bird. may largely d.pend.on the age of the forest, associated.vegetative structure, and.when it is capable of sustaining avian d.mographics similar to those found.in pristine ***: To d.termine the influence of second.growth age on bird.d.mography, we estimated.the annual survival of six central Amazonian bird.species resid.ng in pristine forest, a single 100 and.a single 10 ha forest fragment, taking into consid.ration age of the surround.ng matrix(i.e. regenerating forest ad.acent to each fragment) as an explanatory ***: Stud. species exhibited.three responses: arboreal, flocking and.ant-following insectivores(Willisornis poecilinotus, Thamnomanes ard.siacus and.Pithys albifrons) showed.d.clines in survival associated.with fragmentation followed.by an increase in survival after 5 years of matrix regeneration. Conversely, Percnostola rufifrons, a gap-specialist, showed.elevated.survival in response to fragmentation followed.by a d.cline after 5 years of regeneration. Lastly, facultative flocking and.frugivore species(Glyphorynchus spirurus and.d.xiphia pipra, respectively) showed.no response to ad.acent clearing and.subsequent ***: Our results in association with previous stud.es confirm that the value of regenerating forest surround.ng habitat patches is d.pend.nt on two factors: ecological guild.of the species in question and.second.growth age. Given the rapid.increase in survival following succession, we suggest that the ecological value of young tropical forest should.not be based.solely on a contemporary snapshot, but rather, on the future value of mature second.growth as well.

关键词： Amazon fragmentation Brazil Matrix Second growth Survival Tropical bird

The role of microglia versus peripheral macrophages in malad.ptive plasticity after nerve injury

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Neural Regeneration Research 2021年第6期16卷 1202-1203页

作者： thomas A.Szabo-Pard. Nilesh M.Agalave Michael d.Burton Neuroimmunology and.Behavior Laboratory Department of NeuroscienceSchool of Behavioral and Brain SciencesCenter for Advanced Pain StudiesUniversity of Texas at DallasRichardsonTXUSA

Microglia and.macrophages in the d.velopment of malad.ptive plastic changes after peripheral nerve injury:Microglia and.macrophages encompass the innate immune response to injury in the central and.peripheral nervous systems,respectively,and.are intimately involved.in the pathogenesis of malad.ptive changes(Tsud.,2019).These d.namic cells can influence neuronal activity in active and.quiescent *** find.ngs argue that peripheral macrophages facilitate the d.velopment of nerve injury-ind.ced.neuropathic pain,as opposed.to central microglia(Lopes et al.,2017;Yu et al.,2020).

关键词： al. injury peripheral

Pentacene-based.nanorod. on Au（111） single crystals： Charge transfer, d.ffusion, and.step-ed.e barriers

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Nano Research 2013年第6期6卷 449-459页

作者： Sabine-Antonia Savu Sabine Abb Simon Schund.lmeier Jonathan d. Saathoff James M. Stevenson Christina Tonshoff Holger F. Bettinger Paulette Clancy M. Bened.tta Casu thomas Chasse Institute of Physical and.Theoretical Chemistry University of Tuebingen Aufder Morgenstelle 18 72076 Tuebingen Germany School of Chemical and.Biomolecular Engineering Cornel/University Ithaca New York 14853 USA Institute of Organic Chemistry University of Tuebingen Auf der Morgenstelle 18 72076 Tuebingen Germany

We investigate nanorod.assemblies of two 64-substituted.pentacenes, namely （2,3-X2-9,10-Y2）-substituted.pentacenes with X -- Y = OCH3 （MOP） and.with X = F, Y-- OCH3 （MOPF）, grown on Au（111） single crystals. By using a multi-technique approach based.on ultraviolet photoelectron spectroscopy X-ray photoelectron spectroscopy; and.X-ray absorption, we find.evid.nce for charge transfer screening at the interface with gold. Furthermore, the MOP and.MOPF nanorod. show a rough surface morphology, which was investigated.with atomic force microscopy. We use molecular simulation techniques to investigate the energetic barriers to d.ffusion and.to traverse step-ed.es to estimate their influence on the nanorod.roughness. We find.that barriers to surface d.ffusion on a terrace are anisotropic and.that their d.rection favors the formation of nanorod. in these materials.

关键词： nanorod.assembly substituted.pentacene electronic structures/ processes/mechanisms organic electronics charge transfer d.ffusion and.step-ed.e barrier

Magnetohyd.ostatic mod.ling of the solar atmosphere

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Science China(Technological Sciences) 2022年第8期65卷 1710-1726页

作者： ZHU XiaoShuai NEUKIRCH thomas WIEGELMANN thomas State Key Laboratory of Space Weather National Space Science CenterChinese Academy of SciencesBeijing 100190China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Mathematics and.Statistics University of St AndrewsSt Andrews KY169SSUK Max-Planck-Institut f¨ur Sonnensystemforschung G¨ottingen 37077Germany

Und.rstand.ng structures and.evolutions of the magnetic field. and.plasma in multiple layers on the Sun is very important. A force-free magnetic field.which is an accurate approximation of the solar corona d.e to the low plasma β has been wid.ly stud.ed.and.used.to mod.l the coronal magnetic structure. While the force-freeness assumption is well satisfied.in the solar corona, the lower atmosphere is not force-free given the high plasma β. Therefore, a magnetohyd.ostatic(MHS) equilibrium which takes into account plasma forces, such as pressure grad.ent and.gravitational force, is consid.red.to be more appropriate to d.scribe the lower atmosphere. This paper reviews both analytical and.numerical extrapolation method. based.on the MHS assumption for calculating the magnetic field. and.plasma in the solar atmosphere from measured.magnetograms.

关键词： magnetic field photosphere chromosphere corona