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Impairment of extra-high frequency auditory thresholds in subjects with elevated levels of fasting blood glucose

Journal of Otology 2018年第1期13卷 29-35页

作者： anindya das Ahmed Faisal Sumit Nazmul Ahsan Masashi Kato Nobutaka Ohgami Anwarul Azim Akhand Department of Genetic Engineering and Biotechnology University of Dhaka Dhaka Bangladesh BRAC James P Grant School of Public Health BRAC University Dhaka Bangladesh Department of Occupational and Environmental Health Nagoya University Graduate School of Medicine Nagoya Japan

This study was performed to assess whether there is an association between elevated Fasting Blood Glucose(FBG) and hearing impairment in Bangladeshi population. A total of 142 subjects(72 with elevated FBG; 70 control) were included in the study. The mean auditory thresholds of the control subjects at 1,4,8 and 12 kHz frequencies were 6.35 ± 0.35,10.07 ± 0.91,27.57 ± 1.82, 51.28 ± 3.01 dB SPL(decibel sound pressure level), respectively and that of the subjects with elevated FBG were 8.33 ± 0.66,14.37 ± 1.14, 38.96 土 2.23, and 71.11 ± 2.96 ***. The auditory thresholds of the subjects with elevated FBG were significantly(p 10 years) showed significantly(p 40 years) and younger(<40 years) age groups compared to the respective controls. The binary logistic regression analysis showed a 5.79-fold increase in the odds of extra-high frequency hearing impairment in diabetic subjects after adjustment for age, gender and BMI. This study provides conclusive evidence that auditory threshold at an extra-high frequency could be a sensitive marker for hearing impairment in diabetic subjects.

关键词： Fasting blood glucose Hearing impairment Auditory thresholds Extra-high frequency

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