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A novel oil-in-water drilling mud formulated with extracts from Indian mango seed oil

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Petroleum Science 2020年第1期17卷 196-210页

作者： Saket kumar Aarti thakur Nitesh kumar Maen M.Husein Department of Chemical and Petroleum Engineering The University of CalgaryCalgaryAB T2N 1N4Canada Emerson Innovation Center PuneMaharashtraIndia MDNK Oil and Gas Consultants MumbaiMaharashtraIndia

Drilling muds with less environmental impact are highly desired over conventional diesel-based mud systems,especially in light of the emerging strict environmental *** this article,a novel oil-in-water(O/W)emulsion drilling fluid formulated with a methyl ester extracted from Indian mango seed oil was *** effect of the weight percent of different constituents of the emulsion/suspension including the oil phase,bentonite,and polyanionic cellulose polymer on the rheology and the fluid loss was *** methyl ester oil phase/mud system displayed superior physical,chemical,rheological and filtration properties relative to the diesel and the mango seed ***-toxicity of the methyl ester and diesel(O/W)emulsion mud systems was assessed using the acute lethal concentration *** Indian mango methyl ester(O/W)emulsion mud displayed much less impact on fish *** characteristics collected from the flow model at 85°C suggested excellent shear thinning behavior of the Indian mango methyl ester(IMME)(O/W)emulsion ***,the IMME(O/W)emulsion displayed strong pseudoplastic behavior,an attractive feature in a drilling mud,with increasing clay content and polymer *** methyl ester mud was thermally stable over a wide range of the constituent ***,a particle size analysis revealed that engineered drilling muds targeting suspension of particles with certain size range can be formulated by changing the volume fraction of the methyl ester in the mud system.

关键词： Indian mango seed oil Fluid loss Emulsion drilling mud Shear thinning Pseudoplastic fluid

Alteration in the expression of microRNA-21 regulated target genes:Role in breast cancer

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BIOCELL 2022年第2期46卷 309-324页

作者： PRIYANKA thakur REENA V.SAINI anil K.CHHILLAR NEERAJ K.SAINI VIJAY kumar thakur SAMARJEET SINGH SIWAL ADESH K.SAINI Faculty of Sciences Shoolini UniversitySolan173229India Department of Biotechnology MMECMaharishi Markandeshwar(Deemed to be University)Ambala133207India Maharishi Markandeshwar University Solan173229India Centre of Biotechnology Maharshi Dayanand UniversityRohtak124001India School of Biotechnology Jawaharlal Nehu UniversityNew Delhi110067India Biorefining and Advanced Materials Research Center Scotland’s Rural College(SRUC)EdinburghEH93JGUK Department of Chemistry MMECMaharishi Markandeshwar(Deemed to be University)Ambala133207India

Breast cancer,also recognized as the principal cause of cancer-related deaths among women,is the second most familiar and prevalent form of *** diagnostic and prognostic biomarkers that are highly specific are urgently needed for its early ***(miRNAs),a class of non-coding RNAs,are known to control the biological processes involving transcription,post-transcriptional and covalent modifications,splicing,translation,cell differentiation,proliferation,apoptosis,cancer progression,and *** dysregulation in miRNA expression,demonstrating their oncogenic and tumor-suppressive functions,contributes to cancer ***-21(miR-21),an‘onco-miR’in breast cancer,is involved in tumor progression and metastasis by suppressing the activity of the target gene via its interaction with the 3’UTR of the target *** upregulation of miR-21 is observed in many instances of breast *** review aims to summarize the current understanding of miR-21 in the regulation of important cellular functions via regulation of its target *** discuss its biosynthesis,oncogenic function in breast cancer,and different methods used for its *** will increase the current understanding of the role of miR-21 in breast cancer tumorigenesis,which will offer a perception of using miR-21 as an early detection molecular prognostic and diagnostic biomarker and as a therapeutic target in breast cancer care.

关键词： Non-coding RNA microRNAs Breast cancer Tumor suppression Biomarker

自由取向炭/炭复合材料的新型制备及工艺优化（英文）

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新型炭材料 2018年第5期33卷 424-433页

作者： thakur Sudesh kumar Raunija Rajeev K.Gautam Sharad Chandra Sharma anil Verma Carbon and Ceramics Laboratory Materials and Mechanical EntityVikram Sarabhai Space Centre Indian Space Research OrganisationThiruvananthapuram 695022KeralaIndia Sustainable Environergy Research Lab(SERL) Department of Chemical Engineering Indian Institute of Technology DelhiHauz-KhasNew Delhi 110016India Materials and Metallurgy Group Materials and Mechanical EntityVikram Sarabhai Space Centre Indian Space Research OrganisationThiruvananthapuram 695022KeralaIndia

采用在炭纤维束的内部浸润熔融沥青的传统方法制备得到的炭/炭(C/C)复合材料难以实现细旦化水平,这是因为单束丝中含有数千根丝,经浸渍后沥青附着,从而引起沥青局部渗出,以及因不均匀沥青稳定性而导致微观结构不均匀。本文通过稳定的中... 详细信息

采用在炭纤维束的内部浸润熔融沥青的传统方法制备得到的炭/炭(C/C)复合材料难以实现细旦化水平,这是因为单束丝中含有数千根丝,经浸渍后沥青附着,从而引起沥青局部渗出,以及因不均匀沥青稳定性而导致微观结构不均匀。本文通过稳定的中间相沥青和分散的短切炭纤维混合、热压和炭化过程制备出细旦化水平的C/C复合材料。探讨了工艺参数对中间相沥青残炭率的影响。通过残炭率/工艺时间、残炭率!(表观密度/实密度)来优化工艺参数。结果表明,通过此法得到了细旦化水平的中间相沥青与炭纤维复合材料。中间相沥青的残炭率随加热升温速率、沥青/炭纤维质量比的增加而降低;随热压压力而增加。在高压力和高质量比下,发生沥青局部渗出。通过调控得到最佳的C/C复合材料制备工艺参数为:热压压力15 MPa,升温速率0. 2℃/min及沥青/炭纤维质量比1∶1。

关键词：石油沥青中间相沥青短切炭纤维热压产率

Antimicrobial Materials: New Strategies to Tackle Various Pandemics

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Journal of Renewable Materials 2020年第12期8卷 1543-1563页

作者： Samarjeet Singh Siwal Qibo Zhang Adesh kumar Saini Vijay kumar thakur Key Laboratory of Ionic Liquids Metallurgy Faculty of Metallurgical and Energy EngineeringKunming University of Science and TechnologyKunming650093China Department of Chemistry M.M.Engineering CollegeMaharishi Markandeshwar(Deemed to be University)Mullana-Ambala133207India State Key Laboratory of Complex Nonferrous Metal Resources Cleaning Utilization in Yunnan Province Kunming650093China Department of Biotechnology Maharishi Markandeshwar(Deemed to be University)Mullana-Ambala133207India Biorefining and Advanced Materials Research Center Scotland’s Rural College(SRUC)Kings BuildingsEdinburghUK Department of Mechanical Engineering School of EngineeringShiv Nadar UniversityUttar Pradesh201314India

Coronaviruses are responsible for a developing budgetary,human and fatality trouble,as the causative factor of infections,for example,severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).It has been well recognized that SARS-CoV-2 may survive under severe atmosphere ***,efficient containment approaches,for example,sanitizing,are ***,living compounds contribute a substance of chemical heterogeneity,with antiviral movement,and therefore can have efficacy as therapeutic tools toward coronavirus ***,in this review article,we have described the antimicrobialbased materials,which can be used to inhibit the spreading of the *** have categorized these materials in three sections;(i)antimicrobial wall paint,(ii)antimicrobial papers and(iii)antimicrobial materials surface coating to be utilized as the antimicrobial-based materials for controlling the *** the last section,we have given the concluding remarks with prospects in this area.

关键词： Antimicrobial SARS-CoV-2 wall paint surface coating

Measurement of Hubble constant: were differences in secondary distance indicators apparent as early as the HST Key Project?

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Research in Astronomy and Astrophysics 2021年第3期21卷 97-106页

作者： Rahul kumar thakur Shashikant Gupta Rahul Nigam PK Thiruvikraman Birla Institute of Technology&Science Pilani-Hyderabad CampusIndia G D Goenka University GurgaonHaryana122103India

Different measurements of the Hubble constant(H_(0))are not consistent,and a tension between the CMB based methods and cosmic distance ladder based methods has been *** from various distance based methods are also *** aggravate the problem,the same cosmological probe(TypeⅠa SNe for instance)calibrated through different methods also provides different values of H_(0).We compare various distance ladder based methods through the already available unique data obtained from the Hubble Space Telescope(HST).Our analysis is based on parametric(t-test)as well as non-parametric statistical methods such as the Mann-Whitney U test and Kolmogorov-Smirnov *** results show that different methods provide different values of H_(0) and the differences are statistically *** biases in the calibration would not account for these differences as the data have been taken from a single telescope with a common calibration *** unknown physical effects or issues with the empirical relations of distance measurement from different probes could give rise to these differences.

关键词： Cosmology Supernovae Hubble constant

Harmful algal blooms in fresh and marine water systems： The role of toxin producing phytoplankton

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International Journal of Biomathematics 2016年第3期9卷 191-210页

作者： Nilesh kumar thakur S. K. Tiwari Ranjit kumar Upadhyay Department of MathematicsNational Institute of Technology Raipur 492010 Department of Applied MathematicsIndian School of Mines Dhanbad 826004

In this paper, we have investigated a model with three interacting species： non-toxic phy- toplankton, toxic phytoplankton and zooplankton with Holling type II and III functional responses over the space and time. The role of toxin producing phytoplankton （TPP） has been studied. We have presented the theoretical analysis of pattern formation in spatially distributed population with local diffusion. The paper highlights the hetero- geneity of HABs over space and time. The choice of parameter values and the functional response is important to study the effect of TPP, also it would depend more on the non- linearity of the system. With the help of numerical simulations, we have observed the spatial and spatiotemporal patterns for plankton system. This study demonstrates that TPP plays an important role in controlling the dynamics. We have observed that prey＇s anti-predator efforts promote predator switching. It has been found that high predation of TPP helps for the coexistence of toxic, non-toxic phytoplankton and zooplankton population.

关键词： Plankton harmful algal bloom toxin producing phytoplankton spatiotem-poral pattern.

Ethnobotanical and Indigenous Knowledge of Important Plants in East Hararghe, Eastern Ethiopia

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Journal of Mountain Science 2015年第6期12卷 1521-1533页

作者： Laxman Singh KANDARI Tripti NEGI Ashok kumar thakur Eshetu YILMA Department of Forestry Himgiri Zee University Don Paramedical college and Hospital School of Plant Science College of Agriculture and Environmental Sciences Haramaya University

An ethnobotanical study was conducted in East Hararghe, Ethiopia to identify and investigate the use of various plants by the traditional healers and communities engaged in domestic, pesticide and medicinal use. A total of 78 species were observed to be used by the local inhabitants in the region for the treatments of various ailments. Out of these, herbs constitute 49% followed by trees(36%) and shrubs only 15%. However, most frequently used plant parts were leaf and aerial parts(20) followed by seed(13), fruit(12), other parts(10), rhizome(7) and bark(1). Most of the plants were found to be used for medicinal, aromatic and food flavouring(spices, condiments) purposes. Out of 78 species recorded in the present study, 11 were reported to cure stomachache, seven for cold, cough and respiratory problem, six for diarrhoea and five species were found capable of curing fever. Fabaceae was the largest family contributing to medicinal plant use with seven species followed by Solanaceae, Myrtaceae,(5 spp.), and Zingiberaceae, Asteraceae, Liliaceae(4 spp. each). Some of the important plants utilized for taking care of variety of ailments are Azadirachta indica, Brassica nigra, Balanites aegyptiaca, Maytenus ovatus, Rosmarinus officinalis and Trigonella foenum graecum. Most of these medicinal and aromatic plants(MAPs) play a significant role in the household economy and were observed to be very popular among the people. Unpopular plants were left out of the study. This study provides useful and basic information on usage of different plants for conducting further studies aimed at conservation and documentation of traditional medicine system and economic welfare of rural peoples of the East Hararghe, Ethiopia. It also revealed that indigenous practices contributed to sustainable management of plants.

关键词： Ethnobotany Medicinal plants Primary health care Traditional knowledge East Hararghe

Geochemical Modelling of Fluoride Concentration in Hard Rock Terrain of Madhya Pradesh, India

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Acta Geologica Sinica(English Edition) 2013年第5期87卷 1421-1433页

作者： Jay Krishna thakur Prafull SINGH Sudhir kumar SINGH Bijendra BHAGHEL thakur International & Investment (P) Ltd. Amity Institute of Geo-Informatics and Remote Sensing (AIGIRS) Amity University K.Banerjee Centre of Atmospheric and Ocean Studies IIDS University of Allahabad Department of Earth Sciences Barkatullah University

The aim of the present study is to locate and decipher the groundwater quality, types, and hydrogeochemicai reactions, which are responsible for elevated concentration of fluoride in the Chhindwara district in Madhya Pradesh, India. Groundwater samples, quality data and other ancillary information were collected for 26 villages in the Chhindwara District, M.P. India during May 2006. The saturation index was computed for the selected samples in the region, which suggest that generally most of the minerals are saturated with respect to water. The concentration of fluoride in the region varies from 0.6 to 4.74 rag/l, which is much higher as per the national and international water quality standards. The study also reveals that the fluoride bearing rock formations are the main source of the higher concentration of fluoride in groundwater along with the conjuncture of land use change. Moreover, the area is a hard rock terrain and consists of fractured granites and amygdaloidal and highly jointed compact basalt acting as good aquifer, which is probably enriching the high content of fluoride in groundwater. High concentration of fluoride is found in deeper level of groundwater and it is possible due to rock-water interaction, which requires further detailed investigation. The highly alkaline conditions indicate fluorite dissolution, which works as a major process for higher concentration of fluoride in the study area. The results of this study will ultimately help in the identification of risk areas and taking measures to mitigate negative impacts related to fluoride pollution and toxicity.

关键词： Fluoride rock-water interaction saturation index Madhya Pradesh India

Biopolymers and Biomimetic Materials in Medical and Electronic-Related Applications for Environment-Health-Development Nexus:Systematic Review

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Journal of Bionic Engineering 2022年第6期19卷 1562-1577页

作者： Faris Mohammed AL-Oqla Mohammed Hassouna Alaaeddin Muhammad Enamul Hoque Vijay kumar thakur Department of Mechanical Engineering Faculty of EngineeringThe Hashemite UniversityP.O Box 330127Zarqa13133Jordan University College Fairview 2AJalan TP2Sime UEP Industrial Park Subang Jaya47600Subang JayaSelangorMalaysia Department of Biomedical Engineering Military Institute of Science and Technology(MIST)Mirpur CantonmentDhaka1216Bangladesh Biorefining and Advanced Materials Research Center Scotland’s Rural College(SRUC)Kings BuildingsEdinburghEH93JGUK School of Engineering University of Petroleum&Energy Studies(UPES)Dehradun248007UttarakhandIndia

Biocomposites as bio-inspired materials are produced from renewable resources that are organic and ecofriendly alternative *** improve the lifestyle of human beings as well as enhancing the environmental indices,functional bio-materials are now implemented in various promising *** work has systematically discussed and highlighted the implementations and trends of functional bionic materials in high tech industries,which are necessary for developing modern *** medical,electronic,food and pharmaceutical applications have been ***-inspired materials are used to develop more sustainable possibilities to increase environmental conservation while maintaining customer *** were found employed in several sectors for various functional bio-products including organic thin-film transistors,organic phototransistor,emitting diodes,photodiodes,photovoltaic solar cells,hybrid dental resins,sustainable pharmaceuticals,and food *** are used to create sustainable bio-products for energy storage and harvesting,bone regeneration,nerve damage repair,drug applications and various other industrial subcategories.

关键词： Biopolymers Bioinspired Biomimetic materials Tissue engineering Nerve repair Organic transistors