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Unveiling the brain’s symphony:exploring the necessity and sufficiency of neural networks in behavior control

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Neural Regeneration Research 2025年第1期20卷 186-187页

作者： fernando Jose Bustos Instituto de Ciencias Biomedicas Facultad de Medicina y Facultad de Ciencias de la VidaUniversidad Andres BelloSantiagoChile Millennium Nucleus of Neuroepigenetics and Plasticity(EpiNeuro) SantiagoChile

Since the pioneering work by Broca and Wernicke in the 19th century,who examined individuals with brain lesions to associate them with specific behaviors,it was evident that behaviors are complex and cannot be fully attributable to specific brain areas ***,they involve connectivity among brain areas,whether close or *** that time,this approach was considered the optimal way to dissect brain circuitry and *** pioneering efforts opened the field to explore the necessity or sufficiency of brain areas in controlling behavior and hence dissecting brain ***,the connectivity of the brain and the mechanisms through which various brain regions regulate specific behaviors,either individually or collaboratively,remain largely *** animal models,researchers have endeavored to unravel the necessity or sufficiency of specific brain areas in influencing behavior;however,no clear associations have been firmly established.

关键词： behavior connectivity neural

Unlocking hypoglycemia–associated brain microvascular dysfunction:critical insights from proteomic analysis

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Neural Regeneration Research 2025年第6期20卷 1707-1708页

作者： Siva S.V.P.Sakamuri anil Sakamuri Department of Chemistry Auburn University at MontgomeryMontgomeryALUSA Vascular Biology Center and Department of Medicine Medical College of Georgia at Augusta UniversityAugustaGAUSA

Hypoglycemia-a critical complication linked to worsened brain function in diabetic subjects:Hypoglycemia is characterized by a decline in circulatory glucose levels below sta nda rd physiological *** hypoglycemia,classified as level 1 hypoglycemia,is defined by blood glucose levels below 70 mg/dL and can be effectively addressed through carbohydrate *** hypoglycemia,denoted by blood glucose levels less than 54 mg/dL,poses a life-threatening risk if left *** with type 1 and type 2 diabetes undergoing insulin treatment are particularly susceptible to hypoglycemia due to impaired counterregulatory mechanisms.

关键词： impaired intake critical

Study of intermolecular interactions in binary mixtures of methyl acrylate with benzene and methyl substituted benzenes at different temperatures:An experimental and theoretical approach

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Chinese Journal of Chemical Engineering 2022年第4期35卷 212-238页

作者： anil Kumar Nain Department of Chemistry Dyal Singh College(University of Delhi)New Delhi 110003India

The ultrasonic speeds,u and viscosities,ηof the binary mixtures of methyl acrylate with benzene,toluene,o-xylene,m-xylene,p-xylene,and mesitylene over the whole mole fraction range were measured at six different temperatures and at atmospheric *** the experimental data,the excess isentropic compressibility,κ_(s)^(E),excess ultrasonic speed,u^(E),excess molar isentropic compressibility,K_(s,m)^(E),excess specific impedance,Z^(E)and deviations in viscosity,Δηhave been *** partial molar isentropic compressions,K_(s,m,1) and K_(s,m,2),and excess partial molar isentropic compressions,K_(s,m,1)^(-E) and K_(s,m,2)^(-E) over the whole composition range,partial molar isentropic compressions,K_(s,m,1)^(-)and K_(s,m,2)^(-),and excesspartial molar isentropic compressions,K_(s,m,1)^(-E) and K_(s,m,2)^(-E)of the components at infinite dilution have also been *** results specified the existence of weak interactions between unlike molecules,and these interactions follow the order:benzene>toluene>p-xylene>m-xylene>o-xylene>mesityle *** magnitude of interactions was found to be dependent on the number and position of the methyl groups in these aromatic hydrocarbons.

关键词： Ultrasonic speed Viscosity Methyl acrylate Aromatic hydrocarbon Excess properties Intermolecular interactions

Cosmological Constant Dominated Transit Universe from the Early Deceleration Phase to the Current Acceleration Phase in Bianchi-V Spacetime

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Chinese Physics Letters 2012年第7期29卷 298-302页

作者： YADAV anil Kumar Department of Physics Anand Engineering CollegeKeethamAgra-282007India

We present the transition of the universe from the early decelerating phase to the current accelerating phase with viscous fluid and time-dependent cosmological constant (A) as a source of matter in Bianchi- V *** study the transit behaviour of the universe,we assume the scale factor as an increasing function of time,which generates a time-dependent deceleration parameter (DP).The study revesls that the cosmological term does not change its fundamental nature for ε =const and ε =ε(t),where ε is the coefficient of bulk *** A(t)is found to be positive and is a decreasing function of *** same behavior was observed during recent supernovae *** physical behaviour of the universe is discussed in detail.

关键词： universe behaviour Phase

Anisotropic massive strings in the scalar-tensor theory of gravitation

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Research in Astronomy and Astrophysics 2013年第7期13卷 772-782页

作者： anil Kumar Yadav Department of Physics Anand Engineering College

We present the model of an anisotropic universe with string fluid as the source of matter within the framework of the scalar-tensor theory of gravitation. An exact solution of field equations is obtained by applying Berman＇s law of variation to Hubble＇s parameter which yields a constant value of the deceleration parameter. The nature of classical potential is examined for the model under consideration. It has also been found that the massive strings dominate in the early universe and finally disap-pear from the universe. This is in agreement with current astronomical observations. The physical and dynamical properties of the model are also discussed.

关键词： early universe -- massive strings -- scalar-tensor theory -- classicalpotential

Bianchi-V string cosmological model and late time acceleration

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Research in Astronomy and Astrophysics 2012年第11期12卷 1467-1474页

作者： anil Kumar Yadav Department of Physics Anand Engineering College

We have searched for the existence of the late time acceleration of the universe with string fluid as the source of matter in Bianchi-V space-time. To derive a deterministic solution, we choose the scale factor to be an increasing function of time that yields a time dependent deceleration parameter, representing a model which generates a universe showing a transition from an early decelerating phase to a recent accelerating phase. The study reveals that strings dominate the early universe and eventually disappear from the universe for sufficiently large times, i.e. in the present epoch. This picture is consistent with current astronomical observations. The physical behavior of the universe is discussed in detail.

关键词： early universe -- cosmological parameters

Antibiotic resistome of Salmonella typhi:molecular determinants for the emergence of drug resistance

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Frontiers of Medicine 2021年第5期15卷 693-703页

作者： Awanish Kumar anil Kumar Department of Biotechnology National Institute of TechnologyRaipur-492010(Chhattisgarh)India

Resistome is a cluster of microbial genes encoding proteins with necessary functions to resist the action of *** governs essential and separate biological functions to develop resistance against *** widespread clinical and nonclinical uses of antibiotics over the years have combined to select antibiotic-resistant determinants and develop resistome in *** present,the emergence of drug resistance because of resistome is a significant problem faced by clinicians for the treatment of Salmonella *** resistome is a dynamic and ever-expanding component in *** foundation of resistome in Salmonella is laid long before;therefore,the antibiotic resistome of Salmonella is reviewed,discussed,and *** have searched the literature using PubMed,MEDLINE,and Google Scholar with related key terms(resistome,Salmonella,antibiotics,drug resistance)and prepared this *** this review,we summarize the status of resistance against antibiotics in ***,highlight the seminal work in the resistome of *** and the genes involved in the antibiotic resistance,and discuss the various methods to identify *** resistome for the proactive identification of this infection and quick diagnosis of the disease.

关键词： S.typhi antibiotic resistance mechanism resistome identification methods

Intensive Care Management of Acute Liver Failure:Considerations While Awaiting Liver Transplantation

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Journal of Clinical and Translational Hepatology 2019年第4期7卷 384-391页

作者： anil Seetharam Transplant and Advanced Liver Disease Center University of Arizona College of MedicinePhoenixAZUSA

Acute liver failure is a unique clinical phenomenon charac-terized by abrupt deterioration in liver function and altered *** development of high-grade encephalopathy and multisystem organ dysfunction herald poor ***-specific treatments and supportive measures are routinely employed;however,liver transplantation remains the only chance for cure in those who do not spontaneously *** utility of artificial and bioartificial assist therapies as supportive care—to allow time for hepatic recovery or as a bridge to liver transplantation—has been examined but stud-ies have been small,with mixed *** the severity of derangements,intensive critical care is needed to success-fully bridge patients to transplant,and evaluation of candi-dates occurs rapidly in parallel with serial reassessments of operative *** assessment is often subopti-mal and relative contraindications to transplant,such as ventilator-dependence may be *** often em-ployed to guide evaluation,no single prognostic model dis-criminates those who will spontaneously recover and those who will require *** purpose of this review will be to summarize approaches in critical care,prognostic model-ing,and medical evaluation of the acute liver failure trans-plant candidate.

关键词： Acute liver failure Thromboelastography Intracranial hypertension Liver assist therapy Transplantation

Asymptotic Magnitude Bode Plots of Fractional-Order Transfer Functions

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IEEE/CAA Journal of Automatica Sinica 2019年第4期6卷 1019-1026页

作者： Ameya anil Kesarkar Selvaganesan Narayanasamy IEEE the Space Applications Centre (SAC) Indian Space Research Organization (ISRO)AhmedabadGujaratIndia the Department of Avionics Indian Institute of Space Science and Technology (IIST)ThiruvananthapuramKeralaIndia

Development of asymptotic magnitude Bode plots for integer-order transfer functions is a well-established topic in the control ***,construction of such plots for the fractional-order transfer functions has not received much attention in the existing *** the present paper,we investigate in this direction and derive the procedures for sketching asymptotic magnitude Bode plots for some of the popular fractional-order controllers such as PI^α,[PI]^α,PD^β,[PD]^β,and PI^αD^β.In addition,we deduce these plots for general fractional commensurate-order transfer functions as *** applications of this work,we illustrate 1)the analysis of the designed fractional-control loop and 2)the identification of fractional-order transfer function from a given plot.

关键词： Asymptotic magnitude Bode commensurateorder fractional-order