检索结果-南通市图书馆

Survival and clinical outcomes in patients with metastatic epidural spinal cord compression after spinal surgery:a prospective,multicenter,observational cohort study

引用

Chinese Journal of Cancer 2016年第4期35卷 157-159页

作者： anick nater Michael G.Fehlings Department of Surgery Division of NeurosurgeryUniversity of Toronto Division of Neurosurgery Toronto Western HospitalUniversity Health Network

Background:High quality studies have been challenging to undertake in patients with metastatic epidural spinal cord ***,in the article "Survival and Clinical Outcomes in Surgically Treated Patients With Metastatic Epidural Spinal Cord Compression:Results of the Prospective Multicenter AOSpine Study" recently published in the Journal of Clinical Oncology,our team provided convincing evidence that spinal surgery improves overall quality of life in patients with this potentially devastating complication of *** that metastatic spinal lesions treated with surgery have the highest mean cost among all oncological musculo-skeletal issues,it is essential to provide high quality data to optimize the therapeutic approaches and cost-effective use of health care *** body:Although the AOSpine Study provided high quality prospective data,it was primarily limited by the lack of non-operative controls and the relatively small sample *** the dearth of medical equipoise and the fundamental difference between patients deemed to be adequate surgical candidates and those who are not amenable to operative intervention,conducting a randomized controlled trial in this patient population was not felt to be ethically or medically ***,the optimal option to overcome limitations of both the lack of controls and the relatively small sample size is through collection of large prospective datasets through rigorously developed and maintained ***:With the alarming increase in the incidence of cancer in China and China's parallel growing cancer control efforts,China would offer a fantastic platform to set up a national metastatic spinal lesion *** registry would not only enhance metastatic epidural spinal cord compression translational research but also optimize patient care.

关键词： Metastatic epidural spinal cord compression Prospective study Cohort study Surgery Clinical outcomes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hydraulic Fracturing Stress Measurements and Their Implication for the Design of the First Concrete Lined Pressure Shaft in Sri Lanka

引用

Journal of Hydraulic Engineering 2016年第1期2卷 60-66页

作者： Hadi Barghamadi P. nater P. Huwyler Mahab Ghodss Consulting Engineering Co. Tehran Iran Poyry Switzerland LM. 161 8037 Zurich Switzerland

The Urea Oya Multipurpose Development Project （UMDP） is a water transfer, hydropower and irrigation in the south-eastern part of the central highland region of Sri Lanka. During geotechnical site investigation program 42 hydraulic fracture tests and 42 impression packer tests were carried out in 3 boreholes to about 840 m depth. Based on the stress measurements the minimum and maximum horizontal stress ratios were calculated. In situ stress computations at all the tests were based on the assumption that the principal stress components were vertical （σv） and horizontal （σH and σh, the maximum and minimum, respectively）. The results of the measurements had a direct impact on the design of the major openings bearing a high overburden--the underground powerhouse and the transformer cavern--and revealed a significant optimization potential concerning the selection of the lining system of the pressure shaft.

关键词： Hydraulic fracturing stress measurement in situ stress vertical stress horizontal stress pressure shaft.

来源：

维普期刊数据库评论