检索结果-南通市图书馆

Journal of Sport and Health Science 2021年第4期10卷 510-512页

作者： Kimberley L.Way angelo sabag Angela S.Lee Stephen M.Twigg Nathan A.Johnson School of Exercise and Nutrition Sciences Faculty of HealthDeakin UniversityBurwoodVIC 3125Australia Exercise Physiology and Cardiovascular Health Lab University of Ottawa Heart InstituteOttawaON K1Y 4W7Canada NICM Health Research Institute Western Sydney UniversityWestmeadNSW 2145Australia Central Clinical School Faculty of Medicine and HealthUniversity of SydneyCamperdownNSW 2050Australia Department of Endocrinology Diabetes CentreRoyal Prince Alfred HospitalSydneyNSW 2050Australia Discipline of Exercise and Sports Science Faculty of Medicine and HealthUniversity of SydneyLidcombeNSW 2141Australia Boden Collaboration for Obesity NutritionExercise and Eating DisordersUniversity of SydneyCamperdownNSW 2006Australia

Dear editor,We thank Lopes et al.^(1) for their interest in our study and for writing an insightful commentary based on our findings,which were recently published in the Journal of Sport and Health Science,^(2) and for their work.^(3) As noted by the authors,there is consistency in several key findings between our laboratories,and this should serve as a basis for future investigation in this area.We agree that there has been little work examining the effect of high-intensity interval exercise(HIIE)on central arterial stiffness.

关键词： al. finding thank

Spatial sensitivity to absorption changes for various near-infrared spectroscopy methods:A compendium review

在线全文

学校读者我要写书评

暂无评论

Journal of Innovative Optical Health Sciences 2024年第4期17卷 1-115页

作者： Giles Blaney angelo Sassaroli Sergio Fantini Department of Biomedical Engineering Tufts University 4 Colby StreetMedfordMA 02155USA

This compendium review focuses on the spatial distribution of sensitivity to localized absorption changes in optically diffuse media,particularly for measurements relevant to near-infrared spectroscopy.The three temporal domains,continuous wave,frequency domain,and time domain,each obtain different optical data types whose changes may be related to effective homogeneous changes in the absorption coefficient.Sensitivity is the relationship between a localized perturbation and the recovered effective homogeneous absorption change.Therefore,spatial sensitivity maps representing the perturbation location can be generated for the numerous optical data types in the three temporal domains.The review first presents a history of the past 30 years of work investigating this sensitivity in optically diffuse media.These works are experimental and theoretical,presenting one-,two-,and three-dimensional sensitivity maps for different Near-Infrared Spectroscopy methods,domains,and data types.Following this history,we present a compendium of sensitivity maps organized by temporal domain and then data type.This compendium provides a valuable tool to compare the spatial sensitivity of various measurement methods and parameters in one document.Methods for one to generate these maps are provided in Appendix A,including the code.This historical review and comprehensive sensitivity map compendium provides a single source researchers may use to visualize,investigate,compare,and generate sensitivity to localized absorption change maps.

关键词： Diffuse optics diffusion theory Monte Carlo spatial sensitivity absorption perturbations near-infrared spectroscopy continuous-wave frequency-domain time-domain

Quartz-enhanced multiheterodyne resonant photoacoustic spectroscopy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第4期13卷 696-705页

作者： Jiapeng Wang Hongpeng Wu angelo Sampaolo Pietro Patimisco Vincenzo Spagnolo Suotang Jia Lei Dong State Key Laboratory of Quantum Optics and Quantum Optics Devices Institute of Laser SpectroscopyShanxi UniversityTaiyuan 030006China. Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China. PolySense Lab Dipartimento Interateneo di FisicaUniversity and Politecnico of BariCNR-IFNVia Amendola 17370126 BariItaly

The extension of dual-comb spectroscopy(DCS)to all wavelengths of light along with its ability to provide ultralarge dynamic range and ultra-high spectral resolution,renders it extremely useful for a diverse array of applications in physics,chemistry,atmospheric science,space science,as well as medical applications.In this work,we report on an innovative technique of quartz-enhanced multiheterodyne resonant photoacoustic spectroscopy(QEMR-PAS),in which the beat frequency response from a dual comb is frequency down-converted into the audio frequency domain.In this way,gas molecules act as an optical-acoustic converter through the photoacoustic effect,generating heterodyne sound waves.Unlike conventional DCS,where the light wave is detected by a wavelengthdependent photoreceiver,QEMR-PAS employs a quartz tuning fork(QTF)as a high-Q sound transducer and works in conjunction with a phase-sensitive detector to extract the resonant sound component from the multiple heterodyne acoustic tones,resulting in a straightforward and low-cost hardware configuration.This novel QEMRPAS technique enables wavelength-independent DCS detection for gas sensing,providing an unprecedented dynamic range of 63 dB,a remarkable spectral resolution of 43 MHz(or~0.3 pm),and a prominent noise equivalent absorption of 5.99×10^(-6)cm^(-1)·Hz-1/2.

关键词： Quartz hardware resonant

Ultra-highly sensitive dual gases detection based on photoacoustic spectroscopy by exploiting a long-wave,high-power,wide-tunable,singlelongitudinal-mode solid-state laser

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第5期13卷 941-956页

作者： Shunda Qiao Ying He Haiyue Sun Pietro Patimisco angelo Sampaolo Vincenzo Spagnolo Yufei Ma National Key Laboratory of Laser Spatial Information Harbin Institute of TechnologyHarbinChina PolySense Lab Dipartimento Interateneo di FisicaUniversity and Politecnico of BariVia AmendolaBariItaly

Photoacoustic spectroscopy(PAS)as a highly sensitive and selective trace gas detection technique has extremely broad application in many fields.However,the laser sources currently used in PAS limit the sensing performance.Compared to diode laser and quantum cascade laser,the solid-state laser has the merits of high optical power,excellent beam quality,and wide tuning range.Here we present a long-wave,high-power,wide-tunable,singlelongitudinal-mode solid-state laser used as light source in a PAS sensor for trace gas detection.The self-built solid-state laser had an emission wavelength of~2μm with Tm:YAP crystal as the gain material,with an excellent wavelength and optical power stability as well as a high beam quality.The wide wavelength tuning range of 9.44 nm covers the absorption spectra of water and ammonia,with a maximum optical power of~130 mW,allowing dual gas detection with a single laser source.The solid-state laser was used as light source in three different photoacoustic detection techniques:standard PAS with microphone,and external-and intra-cavity quartz-enhanced photoacoustic spectroscopy(QEPAS),proving that solid-state laser is an attractive excitation source in photoacoustic spectroscopy.

关键词： power tunable tuning

Therapeutic advances in neural regeneration for Huntington’s disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第9期19卷 1991-1997页

作者： Francesco D’Egidio Vanessa Castelli Giorgia Lombardozzi Fabrizio Ammannito Annamaria Cimini Michele d’angelo Department of Life Health and Environmental SciencesUniversity of L’AquilaL’AquilaItaly

Huntington’s disease is a neurodegenerative disease caused by the expansion mutation of a cytosine-adenine-guanine triplet in the exon 1 of the HTT gene which is responsible for the production of the huntingtin (Htt) protein. In physiological conditions, Htt is involved in many cellular processes such as cell signaling, transcriptional regulation, energy metabolism regulation, DNA maintenance, axonal trafficking, and antiapoptotic activity. When the genetic alteration is present, the production of a mutant version of Htt (mHtt) occurs, which is characterized by a plethora of pathogenic activities that, finally, lead to cell death. Among all the cells in which mHtt exerts its dangerous activity, the GABAergic Medium Spiny Neurons seem to be the most affected by the mHtt-induced excitotoxicity both in the cortex and in the striatum. However, as the neurodegeneration proceeds ahead the neuronal loss grows also in other brain areas such as the cerebellum, hypothalamus, thalamus, subthalamic nucleus, globus pallidus, and substantia nigra, determining the variety of symptoms that characterize Huntington’s disease. From a clinical point of view, Huntington’s disease is characterized by a wide spectrum of symptoms spanning from motor impairment to cognitive disorders and dementia. Huntington’s disease shows a prevalence of around 3.92 cases every 100,000 worldwide and an incidence of 0.48 new cases every 100,000/year. To date, there is no available cure for Huntington’s disease. Several treatments have been developed so far, aiming to reduce the severity of one or more symptoms to slow down the inexorable decline caused by the disease. In this context, the search for reliable strategies to target the different aspects of Huntington’s disease become of the utmost interest. In recent years, a variety of studies demonstrated the detrimental role of neuronal loss in Huntington’s disease condition highlighting how the replacement of lost cells would be a reasonable strategy to overcome the neurodegeneration. In this view, num

关键词： cell therapy exosomes extracellular vesicles Huntingtin Huntington’s disease medium spiny neurons neurodegenerative disease neurogenesis neuronal loss stem cells

Hepatocellular carcinoma-the role of the underlying liver disease in clinical practice

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第19期30卷 2488-2495页

作者： angelo Zambam de Mattos Isadora Zanotelli Bombassaro Arndt Vogel Jose D Debes Department of Internal Medicine Universidade Federal de Ciências da Saúde de Porto AlegreRSPorto Alegre 90020090Brazil Graduate Program in Medicine:Hepatology Federal University of Health Sciences of Porto AlegreRSPorto Alegre 90050-170Brazil Division of Gastroenterology Hepatology University of TorontoHannover M5R 0A3Canada Department of Medicine University of MinnesotaMinneapolisMN 55455United States

Hepatocellular carcinoma(HCC)is one of the most common causes of cancerrelated mortality.This particular type of cancer has the distinctive characteristic of mostly happening in individuals with an underlying liver disease.This makes the management of patients more challenging,since physicians must take into consideration two different conditions,the chronic liver disease and the tumor.The underlying liver disease has several implications in clinical practice,because different kinds of chronic liver disease can lead to varying degrees of risk of developing HCC,obstacles in surveillance,and differences in the efficacy of the treatment against HCC.A shift in the prevalence of liver diseases has been evident over the last few years,with viral hepatitis gradually losing the leading position as cause of HCC and metabolic dysfunction-associated steatotic liver disease gaining importance.Therefore,in an era of personalized medicine,it is imperative that physicians are aware of the underlying liver disease of individuals with HCC and its impact in the management of their tumors.

关键词： Hepatocellular carcinoma Etiology Epidemiology Surveillance Therapy

RepDNet:A re-parameterization despeckling network for autonomous underwater side-scan sonar imaging with prior-knowledge customized convolution

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第5期35卷 259-274页

作者： Zhuoyi Li Zhisen Wang Deshan Chen Tsz Leung Yip angelo P.Teixeira Department of Logistics and Maritime Studies The Hong Kong Polytechnic UniversityChina State Key Laboratory of Maritime Technology and Safety Wuhan University of TechnologyChina School of Transportation and Logistics Engineering Wuhan University of TechnologyChina National Engineering Research Center for Water Transport Safety Wuhan University of TechnologyChina Centre for Marine Technology and Ocean Engineering(CENTEC) Instituto Superior TecnicoUniversidade de LisboaPortugal

Side-scan sonar(SSS)is now a prevalent instrument for large-scale seafloor topography measurements,deployable on an autonomous underwater vehicle(AUV)to execute fully automated underwater acoustic scanning imaging along a predetermined trajectory.However,SSS images often suffer from speckle noise caused by mutual interference between echoes,and limited AUV computational resources further hinder noise suppression.Existing approaches for SSS image processing and speckle noise reduction rely heavily on complex network structures and fail to combine the benefits of deep learning and domain knowledge.To address the problem,Rep DNet,a novel and effective despeckling convolutional neural network is proposed.Rep DNet introduces two re-parameterized blocks:the Pixel Smoothing Block(PSB)and Edge Enhancement Block(EEB),preserving edge information while attenuating speckle noise.During training,PSB and EEB manifest as double-layered multi-branch structures,integrating first-order and secondorder derivatives and smoothing functions.During inference,the branches are re-parameterized into a 3×3 convolution,enabling efficient inference without sacrificing accuracy.Rep DNet comprises three computational operations:3×3 convolution,element-wise summation and Rectified Linear Unit activation.Evaluations on benchmark datasets,a real SSS dataset and Data collected at Lake Mulan aestablish Rep DNet as a well-balanced network,meeting the AUV computational constraints in terms of performance and latency.

关键词： Side-scan sonar Sonar image despeckling Domain knowledge Re-parameterization

维普期刊数据库博看期刊

Solid pseudopapillary tumor of the pancreas:A systematic review of clinical,surgical and oncological characteristics of 1384 patients underwent pancreatic surgery

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2024年第4期23卷 331-338页

作者： Gennaro Mazzarella Edoardo Maria Muttillo Diego Coletta Biagio Picardi Stefano Rossi Simone Rossi Del Monte Vito Gomes Irnerio angelo Muttillo Division of General and Emergency Surgery San Filippo Neri Hospital00136 RomeItaly Department of Surgery“Pietro Valdoni” Sapienza University of RomeViale del Policlinico 15500161 RomeItaly Surgical and Medical Department of Translational Medicine Sant’Andrea HospitalSapienza University of Rome00185 RomeItaly Department of Surgical Sciences Umberto I University HospitalSapienza University of Rome00136 RomeItaly Department of General Surgery Ospedali Riuniti Marche Nord61121 PesaroItaly Department of Pathology San Filippo Neri Hospital00136 RomeItaly

Background:Pancreatic solid pseudopapillary tumors(SPTs)are rare clinical entity,with low malignancy and still unclear pathogenesis.They account for less than 2%of exocrine pancreatic neoplasms.This study aimed to perform a systematic review of the main clinical,surgical and oncological characteristics of pancreatic SPTs.Data sources:MEDLINE/PubMed,Web of Science and Scopus databases were systematically searched for the main clinical,surgical and oncological characteristics of pancreatic SPTs up to April 2021,in accordance with the preferred reporting items for systematic reviews and meta-analyses(PRISMA)standards.Primary endpoints were to analyze treatments and oncological outcomes.Results:A total of 823 studies were recorded,86 studies underwent full-text reviews and 28 met inclusion criteria.Overall,1384 patients underwent pancreatic surgery.Mean age was 30 years and 1181 patients(85.3%)were female.The most common clinical presentation was non-specific abdominal pain(52.6%of cases).Mean overall survival was 98.1%.Mean recurrence rate was 2.8%.Mean follow-up was 4.2 years.Conclusions:Pancreatic SPTs are rare,and predominantly affect young women with unclear pathogenesis.Radical resection is the gold standard of treatment achieving good oncological impact and a favorable prognosis in a yearly life-long follow-up.

关键词： Frantz’s tumor Pancreas Pancreatic neoplasms Pancreatic surgery Solid pseudopapillary tumor

Nrf2 and Her3 co-expression in cholangiocarcinoma:Possible biological pathways for potential therapeutic approach

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 317-321页

作者： Paola Parente Valentina Angerilli Giuseppe Zamboni angelo Sparaneo Fabiola Fiordelisi Leonarda Di Candia Matteo Fassan Paolo Graziano Pathology Unit Fondazione IRCCS Casa Sollievo della Sofferenza71013San Giovanni Rotondo(Foggia)Italy Department of Medicine(DIMED) Surgical Pathology UnitUniversity of Padua35128Padua(Padua)Italy Pathology Unit IRCCS Ospedale Sacro Cuore Don Calabria37024Negrar(Verona)Italy Laboratory of Oncology Fondazione IRCCS Casa Sollievo della Sofferenza71013San Giovanni Rotondo(Foggia)Italy Veneto Institute of Oncology IOV-IRCCS 35124Padua(Padua)Italy

To the Editor:Cholangiocarcinomas(CCAs)are heterogeneous group of malignancies,encompassing intrahepatic CCA(iCCA),and extrahepatic CCA(eCCA);they are also classified into common hepatic duct cholangiocarcinoma(CHDCCA),choledocus extrapancreatic cholangiocarcinoma(EPCCA)and choledocus intrapancreatic cholangiocarcinoma(IPCCA)and,finally,gallbladder carcinoma(GBCCA).CCAs are relatively uncommon but.

关键词： carcinoma gallbladder Nrf2

Simple Formulas of πin Terms of Φ

在线全文

学校读者我要写书评

暂无评论

Journal of Applied Mathematics and Physics 2024年第5期12卷 1904-1918页

作者： angelo Pignatelli Independent Researcher Roma Italy

The paper presents a novel exploration of π through a re-calculation of formulas using Archimedes’ algorithm, resulting in the identification of a general family equation and three new formulas involving the golden ratio Φ, in the form of infinite nested square roots. Some related geometrical properties are shown, enhancing the link between the circle and the golden ratio. Applying the same criteria, a fourth formula is given, that brings to the known Dixon’s squaring the circle approximation, thus an easier approach to this problem is suggested, by a rectangle with both sides proportional to the golden ratio Φ.

关键词： π Φ Golden Ratio Squaring the Circle