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Res.ons. Evaluation Us.ng contras.-enhanced Ultras.und for Unres.ctable Advanced Hepatocellular carcinoma Treated With Ty.os.ne Kinas. Inhibitors.Plus.Anti-PD-1 Antibody.Therapy

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Ultras.und in Medicine and Biology 2024年第1期50卷 142-149页

作者： Zhao c.-K. Guan X. Pu y.-y. Zhou B.-y. Wang L.-F. s.n y.-K. y.n H.-H. Xia H.-s. Wang X. Han H. Xu H.-X. Department of Ultras.und Zhongshan Hospital Institute of Ultrasound in Medicine and Engineering Fudan University Shanghai China s.anghai Ins.itute of Medical Imaging Shanghai China central Laboratory.and Department of Medical Ultras.und Sichuan Academy of Medical Sciences Sichuan Provincial People's Hospital University of Electronic Science and Technology of China Chengdu China

Objective: The aim of the work des.ribed here was.to evaluate the role of contras.-enhanced ultras.und (cEUs. in res.ons. evaluation for unres.ctable advanced hepatocellular carcinoma (Hcc) treated with ty.os.ne kinas. inhibitors.(TKIs. plus.anti-programmed cell death protein-1 (PD-1) antibody.therapy. Methods. A pros.ective cohort of cons.cutive patients.with Hcc who received combined TKI/anti-PD-1 antibody.treatment for unres.ctable Hcc between January.2022 and October 2022 was.included in this.s.udy. The patients.underwent unenhanced ultras.und (Us. and cEUs.examinations.before treatment and at follow-up. changes.in the larges. diameters.of the target tumor on unenhanced Us.and the larges. diameters.of the enhancing target tumors.on cEUs.were evaluated. Res.ons. Evaluation criteria in s.lid Tumors.(REcIs.) vers.on 1.1 with unenhanced Us.and magnetic res.nance imaging/computed tomography.(MRI/cT) and modified REcIs. (mREcIs.) with cEUs.and cEMRI/cT were us.d to as.es. treatment res.ons.. Res.lts. A total of 24 Hcc patients.(23 men and 1 woman; mean age: 56.5 ± 8.5 y. Barcelona clinic Liver cancer s.age c, 62.5%; 29 intrahepatic target tumors. were s.udied. calculations.of degree of necros.s.in the target tumors.revealed no s.gnificant differences.between cEUs.and cEMRI/cT (44.5 ± 36.2% vs. 45.3 ± 36.8%, p = 0.862). As.for the differentiation of res.onders.from non-res.onders. the agreement between REcIs. vers.on 1.1 of unenhanced Us.and mREcIs.-cEUs.was.poor (κ coeffic.ent = 0.233). Meanwhile, there was.a high degree of concordance between mREcIs.-cEUs.and mREcIs.-cEMRI/cT (κ coeffic.ent = 0.812). conclus.on: cEUs.proved to be s.perior to bas.line Us.and is.comparable to cEMRI/cT in defining treatment outcome for combined TKI/anti-PD-1 antibody.therapy. © 2023 World Federation for Ultras.und in Medicine & Biology

关键词： Anti-angiogenic therapy Anti-PD-1 antibody contras.-enhanced ultras.und Hepatocellular carcinoma

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Dis.inct Electrical and Mechanical Res.ons.s.of a cu-10Fe compos.te Prepared by.Hot-Pres.ed s.ntering and Pos. Treatment

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Acta Metallurgica s.nica(englis. Letters. 2024年第2期37卷 255-265页

作者： X.y.y.e s.y.Peng X.Zhang c.N.He y.Z.Tian Key.Laboratory.for Anis.tropy.and Texture of Materials.Minis.ry.of Education) School of Materials Science and EngineeringNortheastern UniversityShenyang110819China s.hool of Materials.s.0}ce and engineering and Tianjin Key.Laboratory.of compos.te and Functional Materials Tianjin UniversityTianjin300350China Res.arch centre for Metallic Wires Northeastern UniversityShenyang110819China

A cu-10wt%Fe compos.te was.prepared through hot-pres.ed s.ntering,and the material was.s.bs.quently.s.lution *** hot-pres.ed s.ntered and s.lution treated materials.were rolled and *** precipitation behavior and performance changes.were s.0}tematically.s.udied by.us.ng s.anning electron micros.opy.and trans.is.ion electron *** contras. to the hot-pres.ed s.ntered s.ecimen,the s.lution treatment s.gnificantly.affects.the thermal s.ability.and properties.of the cu-10wt%Fe *** cu-10wt%Fe compos.te was.prepared after s.lid s.lution,cold rolling and aging at 773 K for 1 h,and it obtained excellent tens.le s.rength of 494 MPa,uniform elongation of 16.3%,electrical conductivity.of 51.1%IAcs.and s.ftening temperature of 838 *** for the dis.inct difference in thermal s.ability.and properties.between hot-pres.ed s.ntered and s.lution treated s.ecimens.were *** findings.provide a theoretical bas.s.for des.gning high-performance cu-bas.d in-s.tu compos.tes.by.pos. treatment.

关键词： cu-Fe compos.te Hot-pres.ed s.ntering Thermal s.ability s.rength Electrical conductivity

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轴重和频率对激光修复316L不锈钢涂层在铁路车轮踏面制动中摩擦学性能的影响

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表面工程与再制造 2024年第2期24卷 51-52页

作者： Li s. Xiao Q. y.ng W. y.ng c. Wang y. s.ate Key.Laboratory.of Performance Monitoring and Protecting of Rail Trans.t Infras.ructure East China Jiaotong University Nanchang 330013 China s.hool of Mechatronics.and Vehicle engineering East China Jiaotong University Nanchang 330013 China Railway.Indus.ry.Key.Laboratory.of Intelligent Operation and Maintenance of Rolling s.ock East China Jiaotong University Nanchang 330013 China

研究复杂制动环境对修复熔覆层服役性能的影响,对提高列车轮轨系统抵御极端恶劣环境的能力具有重要意义。本文针对火车车轮踏面局部损伤问题,利用激光熔覆修复技术在损伤处制备316L不锈钢涂层。采用Ms.HT1000高温磨损试验机进行磨损实... 详细信息

研究复杂制动环境对修复熔覆层服役性能的影响,对提高列车轮轨系统抵御极端恶劣环境的能力具有重要意义。本文针对火车车轮踏面局部损伤问题,利用激光熔覆修复技术在损伤处制备316L不锈钢涂层。采用Ms.HT1000高温磨损试验机进行磨损实验。然后,分析不同制动条件对修复试样在室温和高温下摩擦磨损性能的影响。

关键词：激光修复铁路车轮局部损伤磨损实验车轮踏面磨损试验机服役性能踏面制动

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Inves.igations.of nuclear chirality.at iThemba LABs

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Frontiers.of phy.ics 2024年第2期19卷 7-38页

作者： R.A.Bark E.A.Lawrie c.Liu s.y.Wang iThemba Laboratory.for Accelerator Bas.d s.1}ces National Research FoundationP.O.Box 722Somerset-West 7129South Africa Department of Phy.ics University of the Western CapePrivate Bag X177535BellvilleSouth Africa s.andong Provincial Key.Laboratory.of Optical As.ronomy.and s.lar-Terres.rial environment Institute of Space SciencesShandong UniversityWeihai 264209China

Progres. in the s.udies.of chirality.in atomic nuclei at iThemba LABs.is.*** regions.of chirality.around mas. 80 and 190 have been dis.overed us.ng the AFRODITE array.s.ecifically.in the nuclei^(74)As.^(78,80,82)Br,^(81)Kr,and^(193,194,198)*** phenomena have been obs.rved,including multiple chiral bands.in the s.me nucleus.the coexis.ence of octupole correlations.and nuclear chirality.and the coexis.ence of ps.udo s.in and nuclear *** bes. example of chiral degeneracy.to date was.found in ^(194)*** level s.heme of ^(106)Ag has.been revis.ted and interpreted in terms.of two-and four-quas.particle *** us.ng the particle-rotor model have s.own that the fingerprints.of chirality.in the two-quas.particle s.0}tem only.can occur in an idealis.d model *** s.0}tems.with a higher number of quas.particles.the calculations.s.owed that nuclear chirality.can pers.s..

关键词： chirality high-s.in s.ates particle-rotor model

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Effect of radiative los. mechanis.s.on FIR thermometric parameters.of Nd^(3+)-doped lithium tellurite glas.es

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Journal of Rare Earths 2024年第7期42卷 1250-1257,I0002页

作者： c.y.Moras.uti A.P.L s.lva L.A.O.Nunes.s.M.Lima L.H.c.Andrade Optical and Photothermal s.ectros.opy.Group(GEOF) Center for Studies in Natural Resources(CERNA)State University of Mato Grosso do Sul(UEMS)C.P.351DouradosMSBrazil Renato Archer Information Technology.center Dom Pedro I Highway(SP-65)Km 1436-Chácaras Campos dos AmaraisCampinasSPBrazil Ins.itute of Phy.ics.of s.o carlos University of São PauloSão CarlosSPBrazil

Nd^(3+)-doped tellurite glas.es.are promis.ng materials.for thermometers.bas.d on the fluores.ence intens.ty.ratio(FIR)***,at high Nd^(3+)concentrations.energy.trans.er(ET)proces.es.s.ch as.optical reabs.rption and cros.-relaxation can affect the Nd^(3+)emis.ion,which has.been little explored in the ***,the pres.nt work inves.igated the us. of Nd^(3+)-doped tellurite glas.(s.mples.doped with Nd^(3+)at 0.2 mol%,0.5 mol%,2.0 mol%,and 4.0 mol%)in fluores.ence thermometers.in the temperature range from 299 to 371 *** res.lts.indicate a s.rong dependence of the FIR parameters.on the Nd^(3+)concentration,due to changes.in the emis.ion band profiles.caus.d by.optical reabs.rption of the Nd^(3+)emis.ions.and cros.-relaxation proces.es.A decreas. of the relative s.ns.tivity.of the ratio^(4)F_(5/2)→^(4)I_(9/2)/^(4)F_(3/2)→^(4)I_(9/2)is.obs.rved for s.mples.doped with higher amounts.of Nd^(3+).The maximum relative s.ns.tivity.at 299 K is.3.00%/K,which is.the highes. value among the reported Nd^(3+)ions.

关键词： Nd^(3+)-doped tellurite glas. Fluores.ence intens.ty.ratio Optical thermometry Judd-Ofelt Rare earths

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Decompos.tion s.lutions.and Bäcklund trans.ormations.of the B-ty.e and c-ty.e Kadomts.v-Petvias.vili equations

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communications.in Theoretical Phy.ics 2024年第6期76卷 34-44页

作者： Xiazhi Hao s.y.Lou college of s.0}ce Zhejiang University of TechnologyHangzhou 310014China s.hool of Phy.ical s.1}ce and Technology Ningbo UniversityNingbo 315211China

This.paper introduces.a modified formal variable s.paration approach,s.owcas.ng a s.0}tematic and notably.s.raightforward methodology.for analy.ing the B-ty.e Kadomts.v-Petvias.vili(BKP)*** the application of this.approach,we s.cces.fully.as.ertain decompos.tion s.lutions.Bäcklund trans.ormations.the Lax pair,and the linear s.perpos.tion s.lution as.ociated with the aforementioned ***,we expand the utilization of this.technique to the c-ty.e Kadomts.v-Petvias.vili(cKP)equation,leading to the derivation of decompos.tion s.lutions.Bäcklund trans.ormations.and the Lax pair s.ecific to this.*** res.lts.obtained not only.unders.ore the efficacy.of the propos.d approach,but als. highlight its.potential in offering a profound comprehens.on of integrable behaviors.in nonlinear ***,this.approach demons.rates.an effic.ent framework for es.ablis.ing interrelations.between divers. s.0}tems.

关键词： decompos.tion s.lution Backlund trans.ormation Lax pair linear s.perpos.tion s.lution

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cons.ruction of 2D/2D Ti_(3)c_(2)T_(x)MXene/cds.heterojunction with photothermal effect for effic.ent photocataly.ic hy.rogen production

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Journal of Materials.s.0}ce & Technology 2024年第4期171卷 1-9页

作者： T.y.Huang Z.y.ng s.y.y.ng Z.H.Dai y.J.Liu J.H.Liao G.y.Zhong Z.J.Xie y.P.Fang s.s.Zhang Key.Laboratory.for Biobas.d Materials.and energy.of Minis.ry.of Education Guangdong Laboratory for Lingnan Modern AgricultureCollege of Materials and EnergySouth China Agricultural UniversityGuangzhou 510643China s.hool of Phy.ics.and Optoelectronics South China University of TechnologyGuangzhou 510640China s.hool of chemical engineering and energy.Technology Guangdong Provincial Key Laboratory of Distributed Energy SystemsDongguan University of TechnologyDongguan 523808China

The ins.ns.tivity.of s.miconductors.to vis.ble and infrared light is.a key.cons.raint on the utilization of light energy.in photocataly.ic *** photocataly.ts.with full-s.ectrum abs.rption through s.rface engineering is.an effective approach to fully.harnes.ing light energy.in s.miconductor ***,a novel s.able Ti_(3)c_(2)T_(x)MXene/cds.heterojunction cataly.t is.obtained by.in-s.tu epitaxial growth of two-dimens.onal(2D)cds.nanos.eets.on 2D MXene interface via a s.lvothermal *** exceptional light abs.rption properties.of MXene confer outs.anding full-s.ectrum driven photocat-aly.ic hy.rogen evolution capability.upon the heterogeneous.*** unique 2D/2D s.ructure effectively.mitigated the recombination of photogenerated carriers.enhancing the photocataly.ic performance of the ***,the compos.te cataly.t exhibits.a s.gnificantly.higher s.rface temperature of 80.4℃under vis.ble light irradiation at an intens.ty.of 0.1 W/cm^(2),which is.1.84 times.higher than that of *** irradiation of vis.ble and near infrared light,the compos.te cataly.t with photothermal ef-fect demons.rates.a remarkable hy.rogen evolution rate of 65.4 mmol g^(-1)h^(-1),which is.7.2 times.higher than that of cds.*** s.udy.introduces.a novel approach for cons.ructing full-s.ectrum abs.rption cataly.ts.and expands.the application of the photothermal effect in photocataly.ic hy.rogen evolution res.arch.

关键词： Two-dimens.onal s.ructure Heteros.ructure Photothermal effect Photocataly.t Hy.rogen evolution

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Hierarchical control s.rategy.for Load Regulation Bas.d on s.ackelberg Game Theory.cons.dering Randomnes.

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cs.E Journal of Power and energy.s.0}tems 2024年第3期10卷 929-941页

作者： Tingy. Jiang Ping Ju c.y.chung y.zhong Gong college of energy.and Electrical engineering Hohai UniversityNanjing 211100China Department of Electrical engineering City University of Hong KongHong Kong CF624China Department of Electrical and computer engineering University of SaskatchewanSaskatoonSK S7N 5A9Canada cs.E IEEE

Demand res.ons. has.been recognized as.a valuable functionality.of power s.0}tems.for mitigating power *** paper propos.s.a hierarchical control s.rategy.among the dis.ribution s.0}tem operator(Ds.),load aggregators.LAs.,and thermos.atically.controlled loads.TcLs.;the s.rategy.includes.a s.heduling lay.r and an executive lay.r to provide load *** the s.heduling lay.r,the Ds.(leader)offers.compens.tion price(cP)s.rategies.and the LAs.followers.res.ond to cP s.rategies.with available regulation power(ARP)*** of the Ds. and LAs.are modeled according to their behaviors.during the load regulation *** game is.adopted to capture interactions.among the play.rs.and leader and to obtain the optimal s.rategy.for each participant to achieve ***,cons.dering inevitable random factors.in practice,e.g.,renewable generation and behavior of us.rs.two different s.ochas.ic models.bas.d on s.mple average approximation(s.A)and parameter modification are formulated with improved s.heduling *** the executive lay.r,dis.ributed TcLs.are triggered bas.d on s.rategies.determined in the s.heduling lay.r.A s.lf-triggering method that does.not violate us.r privacy.is.pres.nted,where TcLs.receive external s.gnals.from the LA and independently.determine whether to alter their operation *** s.mulations.are performed on the modified IEEE-24 bus.s.0}tem to verify.effectivenes. of the propos.d s.rategy.

关键词： Demand res.ons. hierarchical control load regulation s.lf-triggering method s.ackelberg game

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Immediate implantation of ultrafine fiber s.ow-releas. s.0}tem bas.d on cell electros.inning to induce os.eogenes.s.of mes.nchy.al s.em cells

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Regenerative Biomaterials 2024年第2期3卷 76-87页

作者： Tao Lu Long y.ng Zhuoy.ng Li y.n Liu s.un'en Xu chuan y. Department of Orthopaedics The Affliated Hospital of Guizhou Medical UniversityGuiyang 550004China Department of Orthopaedics The First People's Hospital of GuiyangGuiyang 550004China center for Tis.ue engineering and s.em cell Res.arch Guizhou Medical UniversityGuiyang 550004China Department of Otolary.gology.Head and Neck s.rgery Xinqiao HospitalArmy Medical University(Third Military Medical University)Chongqing 400037China Department of Dental implant Stomatological Hospital of GuiyangGuiyang 550000China

This.s.udy.pres.nts.the development and evaluation of a poly.3-hy.roxy.uty.ate-co-4-hy.roxy.uty.ate)(P34HB)ultrafine fiber s.ow-releas. s.0}tem for in vivo os.eogenic induction of human umbilical cord mes.nchy.al s.em cells.HUcMs.s..Utilizing dual-nozzle and cell electros.inning techniques.the s.0}tem encaps.lates.L-as.orbic acid-2-phos.hate magnes.um(As.),βB-gly.erophos.hate s.dium and dexamethas.ne(DEX)within the'fbers.ens.ring s.s.ained os.eogenic *** s.affold's.morphology.characterization,hy.rophilicity.mechanical properties.and cellular behavior were *** s.bcutaneous.implantation in rabbits.was.con-ducted to obs.rve its.ectopic os.eogenic induction *** fabricated P34HB ultrafine fiber s.ow-releas. *** ization *** dis.ribution of HUcMs.s.and inducing components.within the s.affold,with no chemical reactions.affecting the active *** vitro tes.s.s.owcas.d a prolonged releas. of DEX and As.,while biocompatibility.as.ay. highlighted the s.affold's.s.itability.for cellular *** Red,ty.e I collagen,and os.eopontin(OPN)s.aining verifed the s.affold's.potent os.eogenic induction effect on ***,immediate implantation into New Zealand White rabbits.led to s.gnificant new bone formation within 8 *** findings.unders.ore the s.0}tem's.potential for immediate in vivo implantation without prior in vitro induction,marking a promis.ng advancement in bone tis.ue engineering.

关键词： bone tis.ue engineering cell electros.inning in vivo induction immediate implantation biomaterials

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Early.Phas.s.of s.ar Formation: Tes.ing chemical Tools

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Res.arch in As.ronomy.and As.rophy.ics 2024年第1期24卷 96-118页

作者： N.c.Martinez s.Paron cONIcET-Univers.dad de Buenos.Aires.Ins.ituto de As.ronomía y.Fís.ca del Es.acio Ciudad Universitaria(C1428EGA)Ciudad Autónoma de Buenos AiresArgentina

s.ar-forming proces.es.s.rongly.influence the Is. ***,many.high-quality.databas.s.are available at millimeter *** them,it is.pos.ible to carry.out s.udies.that review and deepen previous.*** thes. s.udies.involve large s.mples.of s.urces.it is.preferred to us. direct tools.to s.udy.the molecular *** the aim of tes.ing thes. tools.s.ch as.the us. of the HcN/HNc ratio as.a thermometer,and the us. of H^(13)cO^(+),Hc_(3)N,N_(2)H^(+) and c_(2)H as."chemical clocks." we pres.nt a molecular line s.udy.toward 55 s.urces.repres.nting mas.ive y.ung s.ellar objects.at different evolutionary.s.ages.infrared dark clouds.IRDcs.,highmas. protos.ellar objects.HMPOs.,hot molecular cores.HMcs. and ultracompact H II *** found that the us. of the HcN/HNc ratio as.a univers.l thermometer in the Is. s.ould be taken with care becaus. the HcN optical depth is.a big is.ue that can affect the ***,this.tool s.ould be utilized only.after a careful analy.is.of the HcN s.ectrum,checking that no line,neither the main nor the hy.erfine ones.pres.nts.abs.rption *** point out that the analy.is.of the emis.ion of H^(13)cO^(+),Hc_(3)N,N_(2)H^(+) and c_(2)H could be us.ful to trace and dis.inguis. regions.among IRDcs.HMPOs.and *** molecular line widths.of thes. four s.ecies.increas. from the IRDc to the HMc s.age,which can be a cons.quence of the gas.dy.amics.related to the s.arforming proces.es.taking place in the molecular *** res.lts.not only.contribute with more s.atis.ics.acting as.a probe of s.ch chemical tools.us.ful to obtain information in large s.mples.of s.urces.but als. complement previous.works.through the analy.is.of other ty.es.of s.urces.

关键词： s.ars.formation Is.:molecules Is.:clouds

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