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厦门大学学报（自然科学版） 2002年第S1期41卷 252-页

作者： Angus Cheung W H Ip angel lai Eva Cheung

Scheduling is one of the most difficult issues in t he planning and operations of the aircraft services industry. In this paper, t he various scheduling problems in ground support operation of an aircraft mainte nance service company are addressed. The authors developed a set of vehicle rout ings to cover each schedule flights; the objectives pursued are the maximization of vehicle and manpower utilization and minimization of operation time. To obta in the goals, an integer-programming model with genetic algorithm is formulated . It is found that the company can produce an effective and efficient schedules to deploy the manpower and equipment resources. Simulation is used to verify the method and a MATLAB program is used to code the genetic algorithm. This model i s further illustrated by a case study in Hong Kong and the benefit elaborated. F inally, a conclusion is made to summarize the experience of this project and pro vide further improvement.

关键词： An Optimization Model for Aircraft Service Logistics

Hybrid assessment of pre-blasting weakening to horizontal section top coal caving (HSTCC) in steep and thick seams

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International Journal of Mining Science and Technology 2014年第1期24卷 31-37页

作者： lai Xingping Shan Pengfei Cao Jiantao Sun Huan Suo Zhengyong Cui Feng College of Energy Engineering Xi'an University of Science and Technology Key Laboratory of Western Mines and Hazard Prevention Ministry of Education of China

Horizontal section top-coal(HSTCC)caving offers a powerful method to efficiently excavate rude coal in steep and thick seams,and pre-blasting weakening has a profound effect on pursuing great production,high efficiency and good benefit under particular conditions like a small-scale working face with large-scale sectional caving height.+564-level HSTCC working face in B3–6coal seams of Jiangou Colliery in Urumqi was taken as study case for in situ industrial *** thickness of seams in the study case is about 50.0 m and average angel here is over 83°.In the industrial experiments,at first we adopted continuous charge machine and emulsion matrix explosive to substitute for traditional blasting schemes for specific geological settings in the study *** analyses and assessments with blasting crack propagation analysis,abutment pressure monitoring prediction and economical benefit assessment were attributed to be able to attest pre-blasting weakening effects *** crack propagation analysis after pre-blasting weakening showed that in all triple monitoring bore holes rock masses of top-coal would be fallen into three stages from the bottom up:fracture zone,plastic zone and elastic zone generally,and fracture toughness respectively in correspondent zones was calculated by the analytical formula:0.5616–0.8806,0.6403–0.9541 and0.7535–1.1900 MPa m1/2after pre-blasting *** monitoring prediction and economical benefit assessment also indicated that it was necessary to introduce the pre-blasting weakening with predominant blasting scheme from both *** excavation in extremely steep and thick coal seams,relevant results would be a useful tool to study the mechanism of pre-blasting weakening both qualitatively and quantitatively.

关键词： Pre-blasting weakening HSTCCS teep and thick seams Explosive scheme In situ hybrid monitoring

Molecular and functional characterisation of inhibitor of apoptosis proteins(IAP,BIRP) in Echinococcus granulosus

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Molecular and functional characterisation of inhibitor of ap...

Analysis of inborn errors of metabolism： disease spectrum for expanded newborn screening in Hong Kong

中国畜牧兽医学会兽医寄生虫学分会第一届青年科学家学术论坛

作者： Jiafei Zhan Hongyu Song Ning Wang Cheng Guo Nengxing Shen Ruiqi Hua Yuan Shi Christiana angel Xiaobin Gu Yue Xie Weimin lai Xuerong Peng Guangyou Yang Department of Parasitology College of Veterinary MedicineSichuan Agricultural University Department of Veterinary Parasitology Faculty of Veterinary SciencesShaheed Benazir Bhutto University of Veterinary and Animal Sciences Department of Chemistry College of Life and Basic ScienceSichuan Agricultural University

The larval stage of Echinococcus granulosussensulato,resulting in cystic echinococcosis-a parasitic zoonosis,causes huge economic losses to the livestock industry and poses a threat to public *** of apoptosis proteins(IAPs) is a class of endogenous anti-apoptotic family,which plays a significant functional role in the regulation of organism’s ***,to explore potential functions of IAPs in ***,two members of IAPs from ***(Eg-IAP and Eg-BIRP) were cloned,expressed,and molecularly ***-IAP and Eg-BIRP encoded putative 331 and 168 residue proteins,*** analysis showed that both proteins contained a BIR domain-the essential functional domain of *** immunohistochemistry revealed that both proteins were ubiquitously localized in all tissues of *** except the infertile *** fluorescent quantitative PCR(RT-qPCR) results revealed relatively higher transcription levels of two Eg-IAPs in protoscoleces(PSCs) compared to the adult worms(18 d).We further used different concentrations of LCL161,a Smac-mimetic pan-IAPs inhibitor,to induce the apoptosis in PSCsin vitro,and revealed that the transcription levels of both genes were negatively correlated with the concentration of *** the results of light microscopy,transmission electron microscopy(TEM),and terminal deoxynucleotidyl transferase dUTP nick end labelling(TUNEL) assay also showed a higher apoptotic rate in PSCs with the increasing concentrations of *** together,our findings provide the reasonable evidence that both Eg-IAP and Eg-BIRP have potential implication in critical anti-apoptotic roles during the development of ***.

关键词： cystic echinococcosis Echinococcus granulosussensulato inhibitor of apoptosis proteins anti-apoptotic roles

来源： cnki会议评论

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Chinese Medical Journal 2011年第7期124卷 983-989页

作者： Han-Chih Hencher Lee Chloe Miu Mak Ching-Wan Lam Yuet-Ping Yuen, angel On-Kei Chan Chi-Chung Shek Tak-Shing Siu Chi-Kong lai Chor-Kwan Ching Wai-Kwan Siu Sammy Pak-Lam Chen Chun-Yiu Law Morris Hok-Leung Tai Sidney Tam Albert Yan-Wo Chan Chemical Pathology Laboratory Department of Pathology Princess Margaret Hospital Hong Kong SAR China Division of Clinical Biochemistry Queen Mary Hospital Hong Kong SAR China Department of Pathology Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong SAR China Chemical Pathology Laboratory Department of Pathology Queen Elizabeth Hospital Hong Kong SAR China

Background Data of classical inborn errors of metabolism （IEM） of amino acids, organic acids and fatty acid oxidation are largely lacking in Hong Kong, where mass spectrometry-based expanded newborn screening for IEM has not been initiated. The current study aimed to evaluate the approximate incidence, spectrum and other characteristics of classical IEM in Hong Kong, which would be important in developing an expanded newborn screening program for the local area.

关键词： biochemical genetics chemical pathology expanded newborn screening Hong Kong," inborn errorsof metabolism tandem mass spectrometry

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股市系统演化方程重正化群解实证研究

系统工程 2007年第2期25卷 56-60页

作者：赖宝全邓贵仕北京大学大连商品交易所博士后工作站辽宁大连116023 大连理工大学系统工程研究所辽宁大连116024

研究股市系统演化方程的重正化群综合因子,并从实际数据中拟合出作为股市要素的股民数量增长情况对综合因子的演化函数。根据所得演化函数分别从时间和增长率两个方面求出了股市系统演化方程的重正化群解。从解的情况来看,其与现实是一... 详细信息

研究股市系统演化方程的重正化群综合因子,并从实际数据中拟合出作为股市要素的股民数量增长情况对综合因子的演化函数。根据所得演化函数分别从时间和增长率两个方面求出了股市系统演化方程的重正化群解。从解的情况来看,其与现实是一致的。

关键词：股市系统层次变换重正化群解变换因子

《天使,望故乡》《时间与河流》中的疾病隐喻与关怀伦理

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浙江外国语学院学报 2018年第1期 86-93页

作者：赖丹琪浙江大学比较文学与世界文学研究所浙江杭州310007

托马斯·沃尔夫的小说《天使,望故乡》《时间与河流》包含了疾病的隐喻机制:疾病被赋予浪漫化的隐喻,体现了精神与肉身的二元对立;但此外,小说也显示了对单向度权力话语系统中的疾病的定义与隐喻的抵制。疾病的隐喻影响了照顾者关怀病... 详细信息

托马斯·沃尔夫的小说《天使,望故乡》《时间与河流》包含了疾病的隐喻机制:疾病被赋予浪漫化的隐喻,体现了精神与肉身的二元对立;但此外,小说也显示了对单向度权力话语系统中的疾病的定义与隐喻的抵制。疾病的隐喻影响了照顾者关怀病人的态度和方式,从而参与进关怀伦理。通过对具体情境的考察,可以发现作品中的关怀者、被关怀者、关怀关系并非僵化不变。沃尔夫的小说呈现了关怀伦理的复杂情境并表达出了理想的关怀关系:疾病的隐喻被消除,"他者"被视为具体化的、异质的他者。

关键词：托马斯·沃尔夫疾病的隐喻关怀伦理《天使望故乡》《时间与河流》

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论美国华裔文学中“根意识”的嬗变

常州大学学报（社会科学版） 2015年第2期16卷 86-90,95页

作者：汪顺来常州工学院外国语学院江苏常州213002

作为美国少数族裔文学中的一个重要分支,美国华裔文学起于19世纪华人移民美国时的"天使岛"诗篇,从早期的《金山歌集》、《埃伦诗集》到20世纪70年代美国华裔小说的崛起,美国华裔文学历经坎坷,逐步登上了美国经典文学的舞台,它是一面镜子... 详细信息

作为美国少数族裔文学中的一个重要分支,美国华裔文学起于19世纪华人移民美国时的"天使岛"诗篇,从早期的《金山歌集》、《埃伦诗集》到20世纪70年代美国华裔小说的崛起,美国华裔文学历经坎坷,逐步登上了美国经典文学的舞台,它是一面镜子,较真实地反映了华人移民在美国的成长经历。由于历史上美国社会对华人的排斥、挤压甚至敌视,华裔及其后代有着强烈的种族和身份意识。中国和中国文化始终是他们无法割舍的"根",但是这种"根意识"也随着华裔在美国特殊的生活经历而发生嬗变,构成了华裔独特的族裔体验。

关键词：美国华裔文学华人移民史根意识族裔体验

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圆锥球头立铣刀的CNC磨削模型及工艺

光学精密工程 2001年第2期9卷 162-164页

作者：来传远金建新华中理工大学机械学院湖北武汉430074

复杂形状刀具结构上的复杂性导致了磨削加工的复杂性。利用圆锥球头立铣刀这一典型复杂形状刀具 ,对其圆锥部分和球头部分的刀刃曲线的连续性进行了分析 ,然后对刀刃结构和加工特性进行研究 ,再利用 Frenet标架来确定砂轮的摆放姿态 ,... 详细信息

复杂形状刀具结构上的复杂性导致了磨削加工的复杂性。利用圆锥球头立铣刀这一典型复杂形状刀具 ,对其圆锥部分和球头部分的刀刃曲线的连续性进行了分析 ,然后对刀刃结构和加工特性进行研究 ,再利用 Frenet标架来确定砂轮的摆放姿态 ,实现利用活动坐标系控制机床坐标的插补进给。

关键词：圆锥球头立铣刀等螺旋角 Frenet标架加工工艺数学模型数控磨销

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文心兰HSP70基因的克隆及表达分析

热带作物学报 2020年第4期41卷 745-754页

作者：冯保云李蓉赖钟雄林玉玲福建农林大学园艺植物生物工程研究所福建福州350002

为研究文心兰热激蛋白70基因(命名为OnHSP70)的分子特性及表达特点,以文心兰‘柠檬绿’(Oncidium hybridum‘Honey angel’)为材料,采用RT-PCR技术克隆OnHSP70,利用生物信息学方法分析其分子特性,通过qRT-PCR技术分析其在不同组织及不... 详细信息

为研究文心兰热激蛋白70基因(命名为OnHSP70)的分子特性及表达特点,以文心兰‘柠檬绿’(Oncidium hybridum‘Honey angel’)为材料,采用RT-PCR技术克隆OnHSP70,利用生物信息学方法分析其分子特性,通过qRT-PCR技术分析其在不同组织及不同非生物胁迫处理下的表达特点。生物信息学分析表明:该基因开放阅读框为1944 bp,编码647个氨基酸,翻译的蛋白为稳定蛋白,属于HSP70超家族,其蛋白二级结构由41.11%的α-螺旋、17.77%的延伸链、7.73%的β-转角和33.38%的无规卷曲组成,具有2个高度保守的功能域。聚类分析表明:该蛋白与铁皮石斛和深圳拟兰的HSP70亲缘关系较近。qRT-PCR分析表明:文心兰HSP70在4种不同组织器官中具有表达差异性,在花中的表达量最高;高温处理后基因的表达量明显上升;40℃高温胁迫4 h时表达量达峰值;茉莉酸甲酯及水杨酸处理时表达量呈现下调响应。本研究为后期该基因功能研究及提高文心兰对高温的适应性提供理论基础。

关键词：文心兰 HSP70 克隆非生物胁迫表达分析