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材料科学与工程（中英文版） 2010年第1期4卷 1-10页

作者： Luis d. Los Santos V angel bustamante d. Lizbet Leon F. Thanos Mitrelias Ad.ian Ionescu JustinianoQuispe M. Crispin H. W. Barnes Cavend.sh Laboratory University of Cambridge J. J Thomson .Av. Cambridge CB3 0HE United Kingdom Facultad.d. Ciencias Fisicas Universidad Nacional Mayor de San Marcos Ap. Postal 14-0149 Peru

Resonance Clustering in Wave Turbulent Regimes:Integrable d.namics

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Communications in Computational Physics 2011年第10期10卷 1211-1240页

作者： Miguel d.bustamante Elena Kartashova School of Mathematical Sciences University College DublinBelfieldDublin 4Ireland IFA J.Kepler UniversityLinz 4040Austria.

Two fund.mental facts of the mod.rn wave turbulence theory are 1)existence of power energy spectra in k-space,and.2)existence of“gaps”in this spectra correspond.ng to the resonance ***,three wave turbulent regimes are singled.out:kinetic,d.scribed.by wave kinetic equations and.power energy spectra;d.screte,characterized.by resonance clustering;and.mesoscopic,where both types of wave field.time evolution *** this review paper we present the results on integrable d.namics of resonance clusters appearing in d.screte and.mesoscopic wave turbulent *** a novel method.based.on the notion of d.namical invariant we show that some of the frequently met clusters are integrable in quad.atures for arbitrary initial cond.tions and.some others-only for particular initial *** also id.ntify chaotic behaviour in some *** implications of the results obtained.are d.scussed.

关键词： Resonance clustering Hamiltonian formulation wave turbulent regimes NRd.agram integrable d.namics.

Statistical analysis to establish an ignition scenario based.on extrinsic and.intrinsic variables of coal seams that affect spontaneous combustion

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International Journal of Mining Science and.Technology 2019年第5期29卷 731-737页

作者： M.O.bustamante Rúa A.J.d.za Aragón P.bustamante Baena J.d.Osorio Botero school mines national university of colombiamedellín 050036colombia

Spontaneous combustion of coal seams in open pit mines is a problem that occurs in coal mines around.the *** have been d.veloped.that express several factors which generate self-heating in the coal and.favor *** synergy of these factors contributes to the increase in the temperature of oxid.tion reactions,facilitating the culmination of the activation energy of the system,in which the ignition d.velops and.the reaction is ***,the incid.nce of each variable’s susceptibility to coal combustion is unknown,so in this work a method.logy was d.veloped.to d.termine statistically which of the variables has the greatest contribution in the *** statistics,atypical values d.tection,principal component d.termination,cluster analysis,and.logistic regression were used.to d.termine how many ind.cator variables are necessary to d.scribe susceptibility to coal *** the analysis,21,000 d.ta from d.fferent seams of two open-pit coal mines in end.alls and.aband.ned.pits were processed.with consid.ration given to extrinsic and.intrinsic *** temperature,atmospheric pressure,wind.speed.oxygen,methane,height,ash,volatile matter,heat power,vitrinite,liptinite and.the Hard.rove Ind.x are the most influential variables in the phenomenon.

关键词： Coal fire Self-ignition Statistics analysis Open pit mines Spontaneous combustion

Optimal thermoelectric figure of merit of Si/Ge core-shell nanowires

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Nano Research 2015年第8期8卷 2611-2619页

作者： Kaike Yang And.es Cantarero angel Rubio Roberto d.Agosta Nano-Bio Spectroscopy Group and.ETSF Scientific d.velopment Center Departamento de Fisica de Materiales Universidad del Pais Vasco UPV/EHU San Sebastian 20018 Spain Instituto d. Ciencia d. Materiales Universidad de Valencia Valencia 46071 Spain Ikerbasque Basque foundation for Science Bilbao 48013 Spain

We investigate the thermoelectric energy conversion efficiency of Si and.Ge nanowires, and.in particular, that of Si/Ge core-shell nanowires. We show how the presence of a thin Ge shell on a Si core nanowire increases the overall figure of merit. We find.the optimal thickness of the Ge shell to provid. the largest figure of merit for the d.vices. We also consid.r Ge core/Si shell nanowires, and.show that an optimal thickness of the Si shell d.es not exist, since the figure of merit is a monotonically d.creasing function of the rad.us of the nanowire. Finally, we verify the empirical law relating the electron energy gap to the optimal working temperature that maximizes the efficiency of the d.vice.

关键词： thermoelectric properties Seebeck coefficient silicon and.germanium core-shell nanowires

Chemotherapy for gastric cancer

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World.Journal of Gastroenterology 2006年第2期12卷 204-213页

作者： Javier Sastre Jose angel García-Saenz Ed.ard. d.az-Rubio Servicio d. Oncologia Méd.ca HCU San Carlosc/Martín Lagos s/n 28040 MadridSpain Servicio d. Oncologia Méd.ca HCU San Carlosc/Martía Lagos s/n 28040 MadridSpain

Metastatic gastric cancer remains a non-curative d.sease. Palliative chemotherapy has been d.monstrated.to prolong survival without quality of life compromise. Many single-agents and.combinations have been confirmed.to be active in the treatment of metastatic d.sease. Objective response rates ranged.from 10-30% for single-agent therapy and.30-60% for polychemotherapy. Results of phase Ⅱ and.Ⅲ stud.es are reviewed.in this paper as well as the potential efficacy of new d.ugs. For patients with localized.d.sease, the role of ad.uvant and.neoad.uvant chemotherapy and.rad.ation therapy is d.scussed. Most stud.es on ad.uvant chemotherapy failed.to d.monstrate a survival ad.antage, and.therefore, it is not consid.recl as stand.rd.treatment in most centres. Ad.uvant immunochemotherapy has been d.veloped.fund.mentally in Korea and.Japan. A meta-analysis of phase Ⅲ trials with OK-432 suggested.that immunochemotherapy may improve survival of patients with curatively resected.gastric cancer. Based.on the results of US Intergroup 0116 stud., postoperative chemorad.ation has been accepted.as stand.rd.care in patients with resected.gastric cancer in North America. However, the results are somewhat confound.d.by the fact that patients und.rwent less than a recommend.d.d. lymph nod. d.ssection and.the pattern of recurrence suggested.a positive effect d.rived.from local rad.otherapy without any effect on micrometastatic d.sease. Neoad.uvant chemotherapy or chemorad.ation therapy remains experimental, but several phase Ⅱ stud.es are showing promising results. Phase Ⅲ trials are need.d.

关键词： Gastric cancer Chemotherapy Ad.uvant treatment

父母苯暴露与儿童白血病危险性的系统综述与meta分析

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父母苯暴露与儿童白血病危险性的系统综述与meta分析

作者： Ed.ar Esteban bustamante angel 东南大学

学位级别：硕士

背景:苯是作为一种挥发性有机化合物,广泛应用于生产和生活中,如干洗、油漆、印刷、橡胶和制鞋业等多个行业,有机溶剂接触是苯暴露的最重要来源之一,研究发现苯暴露与相关职业人群白血病的发生有密切关联。苯可在职业暴露的成年人中引... 详细信息

背景:苯是作为一种挥发性有机化合物,广泛应用于生产和生活中,如干洗、油漆、印刷、橡胶和制鞋业等多个行业,有机溶剂接触是苯暴露的最重要来源之一,研究发现苯暴露与相关职业人群白血病的发生有密切关联。苯可在职业暴露的成年人中引起急性骨髓细胞性白血病和其他血液癌,包括急性淋巴白血病,慢性淋巴白血病,多发性骨髓瘤和非霍奇金淋巴瘤。然而,苯的长期暴露是否可导致儿童患白血病风险增加的证据还有待进一步的阐明。目的:本研究首次通过meta分析研究父母苯(或有关溶剂)暴露接触与其子女患白血病的关联。方法:通过系统综述收集有关成人苯和有机溶剂暴露及其与儿童白血病进一步发生关系的文献。通过电子数据库搜索收集病例对照研究,然后按照PRISMA声明进行筛选。提取数据并收集以创建数据集;其研究随后使用纽卡斯尔-渥太华量表进行质量评估(NOS)进行评估。使用随机效应模型对暴露于苯或溶剂的两个人群(即父母)进行荟萃分析,以计算汇总的效应量ES(比值比)和数据集的95%CI。使用希金斯(Higgins)的I2测试,敏感性分析和亚组分析评估了母亲和父亲暴露组的变量暴露类型(苯或有机溶剂)和白血病类型(未分类的白血病,急性髓系白血病(AML),急性淋巴细胞白血病(ALL)和急性非淋巴细胞白血病(ANLL)的异质性。还使用Begg和Egger检验评估发表偏倚的存在。所有统计分析均使用STATA12软件进行,p值<0.05被认为具有统计学意义。结果:荟萃分析包括14个病例对照研究,其中64%的研究(n=9)评估了父母苯暴露和36%(n=5)的研究评估了父母溶剂暴露。在总共14项研究中,有12项研究涉及母亲暴露,10项涉及父亲暴露。研究共获得28533例白血病病例和45285例对照。对于母亲暴露而言,儿童期白血病患儿的总体ES为1.39(1.02.89),而父亲暴露的ES则为1.18(0.89.55),两组的异质性均较高。当进行亚组分析时,母亲苯暴露的ES为1.75(1.17.61),而父亲苯暴露为ES=1.27(1.03.57);两者对溶剂暴露均无统计学意义。母亲苯暴露的白血病类型的结果与AML病例ES=1.80(1.15.82)和ALL病例ES=1.48(1.10.00)有关;父亲苯暴露为AML病例为ES=1.51(1.08.12),ALL病例为ES=1.19(0.91.56),异质性检验发现,溶剂分组、未分类白血病和母亲暴露的急性淋巴细胞白血病存在显著的异质性。敏感性分析未显示两组的总体效应大小有显着变化;对于发表偏倚,漏斗图显示了父亲暴露组的右偏不对称,而Begg和Egger的检验没有显示有显著的差异。结论:父母苯暴露可增加儿童患白血病的风险,其中母亲暴露的风险更高。父母苯暴露都与儿童AML发生的显著相关,母亲苯暴露与ALL发生显著相关。父母暴露于溶剂与儿童期白血病发生风险之间没有发现显著关联。进一步的研究需要确定父母苯暴露与儿童白血病的作用与机制。

关键词：儿童白血病急性淋巴细胞白血病(ALL) 急性髓系白血病(AML) 父母苯暴露职业苯暴露溶剂暴露挥发性有机化合物

Photoelectrochemical CO_(2) electrolyzers: From photoelectrod. fabrication to reactor configuration

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Journal of Energy Chemistry 2023年第10期85卷 455-480,I0012页

作者： Jose Antonio Abarca Guillermo d.az-Sainz Ivan Merino-Garcia angel Irabien Jonathan Albo d.partamento d. Ingenierías Química y Biomolecular Universidad de CantabriaETSIITAvenida de los Castros s/n39005 SantanderSpain

The photoelectrochemical conversion of CO_(2) into value-ad.ed.prod.cts emerges as an attractive approach to alleviate climate change. One of the main challenges in d.ploying this technology is, however, the d.velopment and.optimization of(photo)electrod.s and.photoelectrolyzers. This review focuses on the fabrication processes, structure, and.characterization of(photo)electrod.s, covering a wid. range of fabrication techniques, from rud.mentary to automated.fabrication processes. The work also highlights the most relevant features of(photo)electrod.s, with special emphasis on how to measure and.optimize them. Finally, the review analyses the integration of(photo)electrod.s in d.fferent photoelectrolyzer architectures, analyzing the most recent research work that comprises photocathod., photoanod.,photocathod.-photoanod., and.tand.m photoelectrolyzer configurations to id.ally achieve self-sustained.CO_(2) conversion systems. Overall, comprehensive guid.lines are provid.d.for future ad.ancements in d.veloping effective d.vices for CO_(2) conversion, brid.ing the gap toward. the use of sunlight as the unique energy input and.practical applications.

关键词： d.carbonization CO_(2)photoelectrored.ction (Photo)Electrod.s Fabrication techniques Photoelectrolyzer configuration

Role of gene polymorphisms in gastric cancer and.its precursor lesions:Current knowled.e and.perspectives in Latin American countries

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World.Journal of Gastroenterology 2014年第16期20卷 4503-4515页

作者： Miguel angel Chiurillo Laboratorio d. Genética Molecular "d..Jorge Yunis-Turbay" Decanato de Ciencias de la SaludUniversidad Centroccidental Lisandro AlvaradoBarquisimeto 3001Venezuela

Latin America shows one of the highest incid.nce rates of gastric cancer in the world.with variations in mortality rates among nations or even within countries belonging to this *** cancer is the result of a multifactorial complex process,for which a multistep mod.l of carcinogenesis is currently *** to the infection with Helicobacter pylori,that plays a major role,environmental factors as well as genetic susceptibility factors are significant players at d.fferent stages in the gastric cancer *** d.fferences in population origin,d.mographic structure,socio-economic d.velopment,and.the impact of globalization lifestyles experienced.in Latin America in the last d.cad.s,all together offer opportunities for stud.ing in this context the influence of genetic polymorphisms in the susceptibility to gastric *** aim of this article is to d.scuss current trend. on gastric cancer in Latin American countries and.to review the available published.information about stud.es of association of gene polymorphisms involved.in gastric cancer susceptibility from this region of the world.A total of 40 genes or genomic regions and.9 genetic variants,58%representing markers involved.in inflammatory response,have been used.in a number of stud.es in which pred.minates a low number of ind.vid.als(cases and.controls)*** of IL-1B(-511 C/T,14 stud.es;-31 T/C,10 stud.es)and.IL-1RN(variable number of tand.m repeats,17 stud.es)are the most represented.ones in the reviewed.*** genetic variants recently evaluated.in large metaanalyses and.associated.with gastric cancer risk were also analyzed.in a few stud.es[e.g.,prostate stem cell antigen(PSCA),Cd.1,Survivin].Further and.better analysis centered.in gene polymorphisms linked.to other covariates,epid.miological stud.es and.the information provid.d.by meta-analyses and.genome-wid. association stud.es should.help to improve our und.rstand.ng of gastric cancer etiology in ord.r to d

关键词： Latin America Gastric cancer Precancerous lesions Gene polymorphisms Single nucleotid. polymorphisms

Corn kernel classification from few training samples

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Artificial Intelligence in Agriculture 2023年第3期9卷 89-99页

作者： Patricia L.Suárez Henry O.Velesaca d.rio Carpio angel d.Sappa ESPOL Polytechnic University CIDISCampus Gustavo GalindoGuayaquil 09-01-5863Ecuador Computer Vision Center Universitat Autònoma de Barcelona08193-BellaterraBarcelonaSpain

This article presents an efficient approach to classify a set of corn kernels in contact,which may contain good.or d.fective kernels along with *** proposed.approach consists of two stages,the first one is a next-generation segmentation network,trained.by using a set of synthesized.images that is applied.to d.vid. the given image into a set of ind.vid.al *** ad.hoc lightweight CNN architecture is then proposed.to classify each instance into one of three categories(ie good.d.fective,and.impurities).The segmentation network is trained.using a strategy that avoid. the time-consuming and.human-error-prone task of manual d.ta *** the classification stage,the proposed.ad.hoc network is d.signed.with only a few sets of layers to result in a lightweight architecture capable of being used.in integrated.*** results and.comparisons with previous approaches showing both the improvement in accuracy and.the red.ction in time are ***,the segmentation and.classification approach proposed.can be easily ad.pted.for use with other cereal types.

关键词： Corn kernel classification Computer vision approaches Quality inspection Food.grain id.ntification Machine vision Instance segmentation Synthesized.d.taset generation

A proctolin-like peptid. is regulated.after baculovirus infection and.med.ates in caterpillar locomotion and.d.gestion

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Insect Science 2022年第1期29卷 230-244页

作者： angel Llopis-Giménez Stefano Parenti Yue Han Vera I.d.Ros Salvad.r Herrero d.partment of Genetics and.Institut Universitari en Biotecnologia i Biomed.cina(BIOTECMEd. Universitat de ValenciaValenciaSpain Laboratory of Virology Wageningen University and ResearchWageningenthe Netherlands Current ad.ress.d.partment of Pathology University of CambridgeCambridgeUK

Baculoviruses constitute a large group of invertebrate d.A viruses, pred.minantly infecting larvae of the insect ord.r Lepid.ptera. d.ring a baculovirus infection, the virus spread. throughout the insect bod. prod.cing a systemic infection in multiple larval tissues, includ.d.the central nervous system (CNS). As a main component of the CNS, neuropeptid.s are small protein-like molecules functioning as neurohormones, neurotransmitters, or neuromod.lators. These peptid.s are involved.in regulating animal physiology and.behavior and.could.be altered.after baculovirus infection. In this stud., we have investigated.the effect of Spod.ptera exigua multiple nucleopolyhed.ovirus (SeMNPV) infection on expression of Spod.ptera exigua neuropeptid.s and.neuropeptid.-like genes. Expression of the gene encod.ng a polypeptid. that resembles the well-known insect neuropeptid. proctolin and.named.as proctolin-like peptid. (PLP), was d.wnregulated.in the larval brain following infection and.was chosen for further analysis. A recombinant Autographa californica multiple nucleopolyhed.ovirus (AcMNPV) overexpressing the C-terminal part of the PLP was generated.and.used.in bioassays using S. exigua larvae to stud. its influence on the viral infection and.insect behavior. AcMNPV-PLP-infected.larvae showed.less locomotion activity and.a red.ction in growth compared.to larvae infected.with wild.type AcMNPV or mock-infected.larvae. These results are ind.cative of this new peptid. as a neuromod.lator that regulates visceral and.skeletal muscle contractions and.offers a novel effector involved.in the behavioral changes d.ring baculovirus infection.

关键词： beet armyworm behavior neuromod.lator neuropeptid. physiology SeM-NPV