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Frontiers of Architectural Research 2019年第2期8卷 175-190页

作者： Xiaoyu DU Regina Bokel andy van den Dobbelsteen Faculty of Architecture and the Built Environment Delft University of TechnologyDelftthe Netherlands Faculty of Architecture and Urban Planning Chongqing UniversityChongqingChina

In the early design stages,architects are in constant search of a design direction that can determine the success or failure of the final ***,in real design practice,most of the prediction methods for building performances,in this paper energy and thermal comfort,are utilised in the later design *** configuration is one of the most important issues for architectural design in the early design *** study investigates the correlations between the spatial indicators connected with architectural design and the building physics indicators ventilation performance and energy *** main objective is to explore the potential of applying spatial indicators using space syntax to predict ventilation performance and energy performance in order to support architects for the evaluation of their concepts and schemes in early design *** layout of a high-rise apartment in China in five different cities is chosen as a case *** results show that the selected three indicators:connectivity value,air change rate and annual cooling saving ratio are linearly correlated,not just at building level but also at room level.R2,the correlation coefficient of determination,is between 0.53 and 0.90(except for the case of Chongqing at building level).

关键词： Space syntax Air change rate Annual cooling saving ratio Connectivity Correlation analysis

Using the ROSS optical streak camera as a tool to understand laboratory experiments of laser-driven magnetized shock waves

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High Power Laser Science and Engineering 2018年第2期6卷 63-68页

作者： andy Liao Patrick Hartigan Gennady Fiksel Brent Blue Peter Graham John Foster Carolyn Kuranz Rice University USA University of Michigan-Ann Arbor USA Lawrence Livermore National Laboratory USA Awe Plc UK

Supersonic flows with high Mach number are ubiquitous in astrophysics. High-powered lasers also have the ability to drive high Mach number, radiating shock waves in laboratory plasmas, and recent experiments along these lines have made it possible to recreate analogs of high Mach-number astrophysical flows under controlled conditions. Streak cameras such as the Rochester optical streak system(ROSS) are particularly helpful in diagnosing such experiments,because they acquire spatially resolved measurements of the radiating gas continuously over a large time interval,making it easy to observe how any shock waves and ablation fronts present in the system evolve with time. This paper summarizes new ROSS observations of a laboratory analog of the collision of a stellar wind with an ablating planetary atmosphere embedded within a magnetosphere. We find good agreement between the observed ROSS data and numerical models obtained with the FLASH code, but only when the effects of optical depth are properly taken into account.

关键词： laser optical systems plasma astrophysics

Rethinking the necessity of low glucose intervention for cerebral ischemia/reperfusion injury

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Neural Regeneration Research 2022年第7期17卷 1397-1403页

作者： Jiahua Xie Farooqahmed S.Kittur P.andy Li Chiu-Yueh Hung Department of Pharmaceutical Sciences Biomanufacturing Research Institute&Technology EnterpriseNorth Carolina Central UniversityDurhamNCUSA

Glucose is the essential and almost exclusive metabolic fuel for the *** stroke caused by a blockage in one or more cerebral arteries quickly leads to a lack of regional cerebral blood supply resulting in severe glucose deprivation with subsequent induction of cellular homeostasis disturbance and eventual neuronal *** make up ischemiamediated adenosine 5′-triphosphate depletion,glucose in the ischemic penumbra area rapidly enters anaerobic metabolism to produce glycolytic adenosine 5′-triphosphate for cell *** appears that an increase in glucose in the ischemic brain would exert favorable *** notion is supported by in vitro studies,but generally denied by most in vivo *** studies to manage increased blood glucose levels after stroke also failed to show any benefits or even brought out harmful effects while elevated admission blood glucose concentrations frequently correlated with poor ***,strict glycaemic control in clinical practice also failed to yield any beneficial *** controversial results from glucose management studies during the past three decades remain a challenging question of whether glucose intervention is needed for ischemic stroke *** review provides a brief overview of the roles of cerebral glucose under normal and ischemic conditions and the results of managing glucose levels in non-diabetic ***,the relationship between blood glucose and cerebral glucose during the ischemia/reperfusion processes and the potential benefits of low glucose supplements for non-diabetic patients are discussed.

关键词： blood-brain barrier blood glucose cerebral glucose glucose intervention glucose transporter glycosylation induced hyperglycemia ischemic penumbra ischemic stroke non-diabetic patients

Biodiversity effects and transgressive overyielding

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Journal of Plant Ecology 2008年第2期1卷 95-102页

作者： Bernhard Schmid andy Hector Prasenjit Saha Michel Loreau Institute of Environmental Sciences University of ZurichWinterthurerstrasse 190CH-8057 ZurichSwitzerland Physics Institute University of ZurichWinterthurerstrasse 190CH-8057 ZurichSwitzerland Department of Biology McGill University1205 ave Docteur PenfieldMontrealQuebecCanada H3A 1B1

Aims The potential for mixtures of plant species to produce more biomass than every one of their constituent species in monoculture is still controversially discussed in the *** we tested how this socalled transgressive overyielding is affected by variation between and within species in monoculture yields in biodiversity *** We use basic statistical principles to calculate expected maximum monoculture yield in a species pool used for a biodiversity *** a real example we show how between-and withinspecies variance components in monoculture yields can be *** the two components we estimate the importance of sampling bias in transgressive overyielding *** Findings The net biodiversity effect(difference between mixture and average monoculture yield)needed to achieve transgressive overyielding increases with the number of species in a mixture and with the variation between constituent species in monoculture *** there is no significant variation between species,transgressive overyielding should not be calculated using the best monoculture,because in this case the difference between this species and the other species could exclusively reflect a sampling *** sampling bias decreases with increasing variation between *** for transgressive overyielding require replicated species’***,it can be doubted whether such an emphasis on monocultures in biodiversity experiments is justified if an analysis of transgressive overyielding is not the major goal.

关键词： biodiversity experiments mixtures monocultures overyielding analysis sampling bias

Tilted spatiotemporal optical vortex with partial temporal coherence [Invited]

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Chinese Optics Letters 2023年第12期21卷 7-10页

作者： Jordan Adams andy Chong Department of Electro-Optics and Photonics University of DaytonDaytonOhio 45434United States Optics and Photonics Riverside Research InstituteBeavercreekOhio 45431United States Department of Physics Pusan National UniversityGeumjeong-GuBusan 46241Republic of Korea

We report the experimental and theoretical investigation of tilted spatiotemporal optical vortices with partial temporal *** theoretical study shows that the instantaneous spatiotemporal optical vortex is widely variable with the statistical orbital angular momentum(OAM)*** decreasing temporal coherence results in a larger variability of OAM tilt,the average OAM direction is relatively unchanged.

关键词： STOVs tilted optical vortex partial temporal coherence optical OAM partially coherent OAM

Nonlinear analysis of pre-tensioned glass wall facade by stability function with initial imperfection

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Frontiers of Structural and Civil Engineering 2010年第3期4卷 376-382页

作者： Siu-Lai CHAN Yaopeng LIU andy LEE Department of Civil and Structural Engineering The Hong Kong Polytechnic UniversityHong KongChina Ove Arup and Partners(Hong Kong)Limited Hong KongChina

Pre-tensioned high strength trusses using alloy steel bar are widely used as glass wall supporting systems because of the high degree of *** breakage of glass panes in this type of system occurs occasionally,likely to be due to error in design and analysis in addition to other factors like glass impurity and stress concentration around opening in a spider *** design does not consider the flexibility of supports from finite stiffness of supporting steel or reinforced concrete *** resistance of lateral wind pressure of the system makes use of high tension force coupled with the large deflection effect,both of which are affected by many parameters not generally considered in conventional *** the design,one must therefore give a careful consideration on various effects,such as support settlement due to live loads and material creep,temperature change,pre-tension force,and wind *** is not uncommon to see many similar glass wall systems fail in the wind load test chambers under a design wind *** paper presents a rigorous analysis and design of this type of structural systems used in a project in Hong Kong,*** stability function with initial curvature is used in place of the cubic function,which is only accurate for linear *** considerations and analysis techniques are believed to be of value to engineers involved in the design of the structural systems behaving nonlinearly.

关键词： tension system glass wall nonlinear analysis pre-tensioning second-order analysis

Analysis of Open Access Landscape

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图书情报工作 2005年第12期49卷 6-13页

作者： Helen Doyle andy Gass Debra Lappin Rebecea Kennison Public Library of Science 185 Berry Street Suite 1300San FranciscoCA 94107USA

This paper is created by bounding 5 editorials of Public Library of Science (PLoS ) which have written on various aspects of open access. It covers wide range topics of important open access issues, such as from paying for open access to copyright to open access as a public issue, which may be more or less of interest of our audience.

关键词：公共图书馆公开文件文献资料图书馆管理

Room-Temperature Phosphorescence and Lifetime of Fossil Resins (Amber) from Dominican Republic, Mexico, Baltic Sea, Myanmar, and Fushun, China

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宝石和宝石学杂志（中英文） 2023年第4期25卷 111-119页

作者： Zhiqing Zhang Yamei Wang andy H.Shen College of Natural Resources and Geographic Information HuBei Land Resources Vocational CollegeWuhan 430090China Gemmological Institute China University of GeosciencesWuhan 430074China

Amber can emit room temperature phosphorescence(RTP)under the well-known 365 nm fluorescence ultraviolet *** paper is devoted to the phosphorescence study of 20 pieces of amber materials from the Dominican Republic,Mexico,Baltic sea,Myanmar,and Fushun,*** results show that amber from the same geographic origin has similar shape in phosphorescence ***,the shape of the amber phosphorescence spectra varies depending on their different ***(amber from Myanmar)and Fushun amber have a bright yellow phosphorescence with a long lifetime,while the Dominican and Mexican ones are weaker and last *** irradiation of Baltic amber becomes faint or even *** spectral Gaussian fitting results suggest an emission maximum near 550 nm in most amber *** phosphorescence lifetime,analyzed through the exponential function fitting,is up to 1 second in Burmite and Fushun samples,shorter in the Dominican and Mexican ones,about 0.230 s,and the shortest in Baltic amber,close to 0.151 *** variations of phosphorescence lifetime and intensity are related to the relative geological ages of these *** indicated that the phosphorescence agent was probably formed during the long geological *** the anomaly occurred in Baltic amber,the only one found in a sea secondary deposit form,it demonstrated that the terrestrial geological environment these amber preserved has prevented the phosphorescence agent to be deactivated.

关键词： ossil resin amber room-temperature phosphorescence(RTP) phosphorescence lifetime

Exercise is recreation not medicine

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Journal of Sport and Health Science 2016年第2期5卷 129-134页

作者： andy Smith York St John University

Purpose： This paper responds to the question, is exercise medicine？ It does so using a qualitative case study that proposes that exercise is recreation. The study （1） describes and reflects upon an exercise is recreation metaphor, （2） establishes the principles and processes used to develop a sport park within which exercise is recreation, and （3） presents a comparative analysis of the exercise is recreation approach with a UK quality framework for ＂exercise referrals＂. Methods： Four years of documentation were collated and placed into 14 categories：（1） university strategies, （2） plans of the site, （3） policy documents, （4） minutes of a steering group, （5） contemporary documents, （6） organisational charts, （7） responses to local government policies on sport, （8） consultation documents, （9） operational procedures, （10） facility specifications, （11） partnership agreements, （12） material relating to the university＇s work on events, （13） notes on the universities sport department, and （14） timetables. These data were analysed through a 4-stage process which used recreation as the analytical theme for a comparative analysis. Results： The characteristics of the exercise is recreation metaphor in this case are （1） a focus on the experience of the user, （2） the promotion of well-being, （3） the importance of community, （4） embracing inclusivity, （5） sport, （6） aesthetics, and （7） leisure time. The principles and processes used to develop the sport park were （1） custodianship, （2） partnerships, （3） values, （4） inter-professional working, （5） local heritage, （6） change, （7） the natural park environment, and （8）＂riding the bike as you build it＂. The comparative analysis with a UK quality framework for ＂exercise referrals＂ clearly shows a difference from an exercise is recreation approach. Conclusion： Exercise is recreation and may enable individuals and communities to reach a state of well-being. ~ 2016 Production and hosting by Elsevier B.V. on behalf of Shanghai University

关键词： Case study Exercise Medicine Recreation

Identification and functional analysis of heterogeneous FOXP3^+ Treg cell subpopulations in human pancreatic ductal adenocarcinoma

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Science Bulletin 2018年第15期63卷 972-981页

作者： Gang Yi Shiwei Guo Wenyu Liu Huan Wang Rendong Liu andy Tsun Gang Jin Bin Li Shanghai Key Laboratory of Bio-energy Crops School of Life Science Shanghai University Shanghai Institute of Immunology Shanghai Jiao Tong University School of Medicine Department of Immunology and Microbiology Shanghai Jiao Tong University School of Medicine CAS Center for Excellence in Molecular Cell Science Unit of Molecular Immunology Institute Pasteur of Shanghai Shanghai Institutes for Biological Sciences University of Chinese Academy of Sciences Medical School Chinese Academy of Sciences Department of General Surgery Changhai Hospital Second Military Medical University

CD4^＋ CD25^＋ regulatory T （Treg） cells express the transcription factor FOXP3 and play an essential role in preventing autoimmunity. Abundant Treg cell accumulation in tumors and tumor draining lymph nodes （TDLNs） has been reported to correlate with both poor and favorable prognosis in various cancers, which suggests that Tregs may have multiple effects on antitumor immunity. However, the heterogeneity of tumor- and TDLN-infiltrating Treg cells remains unclear. Here we provide heterogeneity analysis of tumor infiltrating human CD4^＋ Treg cells and their matched adjacent tissues and TDLNs. We defined three different subpopulations of tumor- and TDLN-infiltrating Treg cells by Helios and CCR8 expression in pancreatic ductal adenocarcinoma （PDAC） and confirmed their functional heterogeneity. Helios^＋ CCR8^＋ Treg cells with potent suppressor function and limited IL-2 and IFN-7 secretion were identified in tumors and TDLNs. On the contrary, Helios^- CCR8^- Treg cells have impaired suppressive activity, and elevated expression of pro-inflammatory cytokines. More advanced grades of PDAC have predominantly Helios^＋ CCR8^＋ Treg cells and few Helios^- CCR8^- Treg cells both in tumors and TDLNs that suggests poor prognosis. These data could help further define the role of Treg cells and their functional role in tumors and TDLNs.

关键词： Pancreatic ductal adenocarcinoma Regulatory T cells Heterogeneity Tumor draining lymph nodes