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Tumor differentiation as related to sentinel lymph node status in gastric cancer

World Journal of Gastrointestinal Surgery 2014年第1期6卷 1-4页

作者： Ron Lavy andronik kapiev Yehuda Hershkovitz Natan Poluksht Igor Rabin Bar Chikman Zahar Shapira Ilan Wasserman Judith Sandbank Ariel Halevy Division of Surgery Assaf Harofeh Medical Center Sackler Faculty of Medicine Tel-Aviv University Department of Vascular Surgery Assaf Harofeh Medical Center Sackler Faculty of Medicine Tel-Aviv University Institute of Pathology Assaf Harofeh Medical Center Sackler Faculty of Medicine Tel-Aviv University

AIM:To investigate the influence of tumor grade on sentinel lymph node(SLN)status in patients with gastric cancer(GC).METHODS:We retrospectively studied 71 patients with GC who underwent SLN mapping during gastric surgery to evaluate the relationship between SLN status and tumor ***:Poorly differentiated tumors were detected in 50/71 patients,while the other 21 patients had moderately differentiated *** were identified in 58/71 patients(82%).In 41 of the 58 patients that were found to have stained nodes(70.7%),the tumor was of the poorly differentiated type(groupⅠ),while in the remaining patients with stained nodes 17/58(29.3%),the tumor was of the moderately differentiated type(groupⅡ).Positive SLNs were found in22/41 patients in group I(53.7%)and in 7/17 patients in groupⅡ(41.2%)(P=0.325).The rate of positivity for the SLNs in the two groups(53.7%vs 41.2%)was not statistically significant(P=0.514).CONCLUSION:Most of our patients were found to have poorly differentiated adenocarcinoma of the stomach and there was no correlation between tumor grade and SLN involvement.

关键词： Gastric cancer Sentinel lymph nodes Tumor differentiation Sentinel lymph node mapping Prognosis

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