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Detection of Oxygen-induced Changes in Retina Using Magnetic Resonance Imaging:A Human Study

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Detection of Oxygen-induced Changes in Retina Using Magnetic...

Inkj.t Printed Metamaterial Loaded Antenna for WLAN/WiMAX Applications

中华医学会第16次全国放射学学术大会

作者： Q Xu Beij.ng CHINA Q Chen Z Wang md PhD j.Xian md

PURPOSE Inner retinal oxygenation response(ΔPO2) is a worldwide-existing study ***, the relevant reports on its radiological methods are *** this study,whether or not magnetic resonance imaging(MRI) was used to detect changes inΔPO2 following 100%oxygen inhalation by employing T1 weighted image(T1WI) in human subj.cts was discussed.

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Computers, Materials & Continua 2022年第5期71卷 2271-2284页

作者： Farhad Bin Ashraf Touhidul Alam md Tarikul Islam Mandeep j.t Singh Norbahiah Binti Misran Mohammad Tariqul Islam Department of Electrical Engineering Polytechnique MontréalMontréalQC H3T 1J4Canada Space Science Centre(ANGKASA) Institute of Climate Change(IPI)Universiti Kebangsaan MalaysiaBangi43600SelangorMalaysia Department of Electrical Electronic and Systems EngineeringFaculty of Engineering and Built EnvironmentUniversiti Kebangsaan MalaysiaMalaysia

In this paper,the design and performance analysis of an Inkj.tprinted metamaterial loaded monopole antenna is presented for wireless local area network(WLAN)and worldwide interoperability for microwave access(WiMAX)*** proposed metamaterial structure consists of two layers,one is rectangular tuning fork-shaped antenna,and another layer is an inkj.t-printed metamaterial *** metamaterial layer is designed using four split-ring resonators(SRR)with an H-shaped inner structure to achieve negative-index metamaterial *** metamaterial structure is fabricated on low-cost photo paper substrate material using a conductive inkbased inkj.t printing technique,which achieved dual negative refractive index bands of 2.25–4.25 GHz and 4.3–4.6 *** antenna is designed using a rectangular tuning fork structure to operate at WLAN and WiMAX *** antenna is printed on 30×39×1.27 mm3 Rogers RO3010 substrate,which shows wide impedance bandwidth of 0.75 GHz(2.2 to 2.95 GHz)with 2 dB realized gain at 2.4 *** integrating metamaterial structure,the impedance bandwidth becomes 1.25 GHz(2.33 to 3.58 GHz)with 2.6 dB realized gain at 2.4 *** antenna bandwidth and gain have been increased using developed quad SRR based metasurface by 500 MHz and 0.6 dBi ***,the proposed quad SRR loaded antenna can be used for 2.4 GHz WLAN bands and 2.5 GHz WiMAX *** contribution of this work is to develop a cost-effective inj.ct printed metamaterial to enhance the impedance bandwidth and realized the gain of a WLAN/WiMAX antenna.

关键词： Metamaterial epsilon negative antenna split ring resonator WiMAX WLAN

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输血相关急性肺损伤：临床新观点

麻醉与镇痛 2010年第3期6卷 12-19页

作者： Darrell j. Triulzi, md 李立晶(译) 岳云(校) Department of Pathology Division of Transfusion Medicine University of Pittsburgh Medical Center Institute for Transfusion Medicine Pittsburgh Pennsylvania 不详

在美国，输血相关急性肺损伤（TRALI）在输血相关致病率和死亡率统计中成为首要原因。TRALI的诊断标准近年来有所改进，主要包括发生于输血过程中或输血后6小时内出现的缺氧和双侧肺水肿，而患者本身无心衰或血管内容量超负荷。输血相... 详细信息

在美国，输血相关急性肺损伤（TRALI）在输血相关致病率和死亡率统计中成为首要原因。TRALI的诊断标准近年来有所改进，主要包括发生于输血过程中或输血后6小时内出现的缺氧和双侧肺水肿，而患者本身无心衰或血管内容量超负荷。输血相关循环超负荷是主要的鉴别诊断，并且鉴别有一定困难。治疗需要氧气和机械通气的辅助，不需要使用利尿剂，激素的效果也没有得到证实。患者通常在几天内可以恢复。各种血液制品都会；l起TRALI，但是血浆成分丰富的制品，如新鲜冰冻血浆和浓缩血小板是最常见的诱因。TRALI的发病机制尚不完全清楚。捐献者血浆中的白细胞抗体几乎存在于所有病例中，这些抗体针对I型人类白细胞抗原（HLAI）、HLAⅡ或中性粒细胞特异性抗原，特别是HNA-3a。在外科和ICU患者中常可观察到，激活肺内皮细胞在TRALI的病情发展中有重要作用。输入的白细胞凝集抗体与受血者的中性粒细胞结合，聚集在肺内皮组织局部，激活和释放氧化酶，发生其他有害生物反应导致血管变得脆弱。在少数TRALI病例中，没有发现抗体，推测输入血中的中性粒细胞刺激因子可以在肺内皮细胞已经激活的患者中引起TRALI，这被称为“双重打击”机制。了解抗白细胞抗体的作用，使医生有新的办法降低TRALI的发生危险。曾经妊娠过的女性捐赠者有24％的人血液中通常会存在HLA抗体，并且随着妊娠次数的增加存在抗体的可能性也增大。随着在TRALI中发现HLA抗体，血液中心采取了尽量从男性捐赠者血液中提取血浆成分的方法。输入浓缩血小板时怎样降低发病风险尚存在疑问，并且可能需要对女性捐赠者进行血小板HLA抗体检测。我们需要更多有关血液成分和TRALI致病危险因素的研究，从而制定新的治疗方案，以便有更多方法减少TRALI的发生。

关键词：输血相关急性肺损伤 TRALI 白细胞抗体 ICU患者 HLA抗体浓缩血小板中性粒细胞人类白细胞抗原

Association between Helicobacter pylori infection,mismatch repair,HER2 and tumor-infiltrating lymphocytes in gastric cancer

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World j.urnal of Gastrointestinal Oncology 2024年第6期16卷 2487-2503页

作者： Carlos A Castaneda Miluska Castillo Luis A Bernabe j.selyn Sanchez Matteo Fassan Katherine Tello Ignacio Ivan Wistuba Ivan Chavez Passiuri Eloy Ruiz j.venal Sanchez Fernando Barreda Daniel Valdivia Yaqueline Bazan Milagros Abad-Licham Claudio Mengoa Hugo Fuentes Paola Montenegro Ebert Poquioma Raul Alatrista Claudio j.Flores Luis Taxa Faculty of Health Sciences Universidad Cientifica del SurLima 15038Peru GECO PERU Grupo de Estudios Clinicos Oncologicos del PeruLima 15038Peru Department of Research Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Faculty of Human Medicine Universidad Ricardo PalmaLima 15039Peru Department of Medicine Surgical Pathology&Cytopathology UnitUniversity of PaduaPadua 35121Italy Department of Translational Molecular Pathology The University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Department of Abdominal Surgery Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Department of Pathology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Department of Medical Specialties Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Department of Pathology Instituto Regional de Enfermedades Neoplasicas del NorteTrujillo 13001Peru Faculty of Human Medicine Universidad Privada Antenor OrregoTrujillo 13008Peru Department of Surgery Instituto Regional de Enfermedades Neoplasicas del SurArequipa 04002Peru Department of Medical Oncology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Department of Epidemiology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Unidad de Investigación Básica y Traslacional Oncosalud-AUNALima 15038Peru Faculty of Medicine Universidad San Martin de PorresLima 15008Peru

BACKGROUND The influence of Helicobacter-pylori(***)infection and the characteristics of gastric cancer(GC)on tumor-infiltrating lymphocyte(TIL)levels has not been extensively *** of infiltrating-immune-cell subtypes as well as survival is necessary to obtain comprehensive *** To determine the rates of deficient mismatch-repair(dMMR),HER2-status and *** infection and their association with TIL levels in *** Samples from 503 resected GC tumors were included and TIL levels were evaluated following the international-TILs-working-group recommendations with assessment of the intratumoral(IT),stromal(ST)and invasive-border(IB)*** density of CD3,CD8 and CD163 immune cells,and dMMR and HER2-status were determined by immunohistochemistry(IHC).*** infection was evaluated by routine histology and quantitative PCR(qPCR)in a subset of *** dMMR was found in 34.4%,HER2+in 5%and ***-positive in 55.7%of *** IT-TIL was associated with grade-3(P=0.038),while ST-TIL with grade-1(P<0.001),intestinal-histology(P<0.001)and no-recurrence(P=0.003).dMMR was associated with high TIL levels in the ST(P=0.019)and IB(P=0.01)compartments,and STCD3(P=0.049)and ST-CD8(P=0.05)***2-was associated with high IT-CD8(P=0.009).*** was associated with high IT-TIL levels(P=0.009)when assessed by routine-histology,and with high TIL levels in the 3 compartments(P=0.002-0.047)and CD8 density in the IT and ST compartments(P=0.001)when assessed by qPCR.A longer overall survival was associated with low IT-CD163(P=0.003)and CD8/CD3(P=0.001 in IT and P=0.002 in ST)and high IT-CD3(P=0.021),ST-CD3(P=0.003)and CD3/CD163(P=0.002).CONCLUSION TIL levels were related to dMMR and *** CD8/CD3 and high CD163/CD3 were associated with lower recurrence and longer survival.

关键词： Lymphocytes Macrophages Gastric cancer Helicobacter pylori HER2 Mismatch repair

The ReaxFF reactive force-field: development, applications and future directions

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npj.Computational Materials 2016年第1期2卷 202-215页

作者： Thomas P Senftle Sungwook Hong md Mahbubul Islam Sudhir B Kylasa Yuanxia Zheng Yun Kyung Shin Chad j.nkermeier Roman Engel-Herbert Michael j.j.nik Hasan Metin Aktulga Toon Verstraelen Ananth Grama Adri CT van Duin Department of Chemical Engineering Pennsylvania State UniversityUniversity ParkPAUSA Department of Mechanical and Nuclear Engineering Pennsylvania State UniversityUniversity ParkPAUSA Department of Computer Science and Engineering PurdueWest LafayetteINUSA Department of Materials Science and Engineering Pennsylvania State UniversityUniversity ParkPAUSA Department of Computer Science and Engineering Michigan State UniversityEast LansingMIUSA Center for Molecular Modeling(CMM) Ghent UniversityZwijnaardeBelgium

The reactive force-field(ReaxFF)interatomic potential is a powerful computational tool for exploring,developing and optimizing material *** based on the principles of quantum mechanics(QM),while offering valuable theoretical guidance at the electronic level,are often too computationally intense for simulations that consider the full dynamic evolution of a ***,empirical interatomic potentials that are based on classical principles require significantly fewer computational resources,which enables simulations to better describe dynamic processes over longer timeframes and on larger *** methods,however,typically require a predefined connectivity between atoms,precluding simulations that involve reactive *** ReaxFF method was developed to help bridge this *** the gap from the classical side,ReaxFF casts the empirical interatomic potential within a bond-order formalism,thus implicitly describing chemical bonding without expensive QM *** article provides an overview of the development,application,and future directions of the ReaxFF method.

关键词： properties directions bonding

The impact of hearing impairment and noise-induced hearing inj.ry on quality of life in the active-duty military population:challenges to the study of this issue

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j.urnal of Medical Colleges of PLA(China) 2016年第3期31卷 153-161页

作者： Hasanat Alamgir Caryn A.Turner Nicole j.Wong Sharon P.Cooper j.se A.Betancourt j.mes Henry andrew j.Senchak Tanisha L.Hammill Mark D.Packer Deptartment of Health Policy and Management School of Health Sciences and PracticeNew York Medical CollegeValhallaNY 10595USA School of Public Health The University of Texas Health Science Center at Houston7411 John Smith Drive Suite 1100 San AntonioTX 78229USA National Center for Rehabilitative Auditory Research 3710 SW US Veteran Hospital RoadPortlandOR 87239USA Walter Reed National Military Medical Center 8901 Wisconsin AveBethesdaMD 20814USA Department of Defense Hearing Center of Excellence 59MDW/SG02O2200 Bergqiust Drive Suite 1JBSA LacklandTX 78236USA.

The obj.ctives of this review were to 1)summarize the available evidence on the impact of hearing loss on quality of life(QOL)among ***-duty service members,2)describe the QOL instruments that have been used to quantify the impact of hearing loss on quality of life,3)examine national population-level secondary databases and report on their utility for studying the impact of hearing loss on QOL among active-duty service members,and 4)provide recommendations for future studies that seek to quantify the impact of hearing loss in this *** is a lack of literature that addresses the intersection of hearing impairment,the military population,and quality of life *** audiological research,*** personnel offer a unique research population,as they are exposed to noise levels and blast environments that are highly unusual in civilian work settings and can serve as a model population for studying the impact on QOL associated with these *** review recommends conducting a study on the active-duty service member population using a measurement instrument suitable for determining decreases in QOL specifically due to hearing loss.

关键词： Quality of life(QOL) Hearing impairment Noise-induced hearing inj.ry Hearing loss Tinnitus Hearing impairment and noise-induced hearing inj.ry(HINIHI) Military Service members

CYTOKINE-INDUCED MOBILIZATION OF ENDOTHELIAL PROGENITOR CELLS ENHANCES REPAIR OF INj.RED ARTERIES

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Mucosal Schwann Cell Hamartoma—Colonic Lesion Susceptible to an Interesting Differential Diagnosis

第2届世界华人生物医学工程研讨会

作者： Luis G. Melo, PhD Choong C Liew, PhD Richard E. Pratt, PhD Victor j. Dzau, md Department of Medicine Brigham and Women’s Hospital Harvard Medical School Boston MA 02115 USA Department of Physiology Queen’s University 20 Stuart Street Kingston Ontario K7L 3N6 Canada Department of Medicine Brigham and Women’s Hospital Harvard Medical School Boston MA 02115 USA Department of Medicine Brigham and Women’s Hospital Harvard Medical School Boston MA 02115 USA Department of Medicine Brigham and Women’s Hospital Harvard Medical School Boston MA 02115 USA

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Open j.urnal of Pathology 2018年第3期8卷 101-105页

作者： j.Ortiz L.Chinchilla E.Munoz md Ludena Department of Pathological Anatomy of the University Hospital of Salamanca SalamancaSpain

We present a mucosal Schwann cell hamartoma that was observed in a 63-year-old woman with no personal or family history of interest who underwent a screening colonoscopy for early detection of colon cancer. During colonoscopy, a small polyp with a maximum diameter of 0.8 cm was detected at the rectosigmoid level. Histologically, a benign lesion of neuroid aspect was observed, consisting of multiple spindle cell fascicles that was positive for S-100 and negative for enolase, synaptophysin, CD34, CD117, actin, desmin, Dog1, EMA, and neurofilaments. These findings, supported by the family and personal history of the patient, allowed us to make a diagnosis, discarding other entities.

关键词： Schwann Cell Hamartoma Immunohistochemistry

Analysis and design of steel-concrete composite sandwich systems subj.cted to extreme loads

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Frontiers of Structural and Civil Engineering 2011年第3期5卷 278-293页

作者： Kazi md Abu SOHEL j.t Yuen Richard LIEW Min Hong ZHANG Department of Civil Engineering National University of Singapore Singapore

This paper presents the design guide based on analytical,numerical and experimental investigation of Steel-concrete-steel(SCS)sandwich structural members comprising a lightweight concrete core with density ranged from 1300 to 1445 kg/m3 subj.cted to static,impact and blast *** performance of lightweight sandwich members is also compared with similar members with normal weight concrete core and ultra high strength concrete core(fc=180 MPa).Novel j.hook shear connectors were invented to prevent the separation of face plates from the concrete core under extreme loads and their uses are not restricted by the concrete core *** and punching are the primary modes of failure under static point *** test results show that the SCS sandwich panels with the j.hook connectors are capable of resisting impact load with less damage in comparison than equivalent stiffened steel plate *** tests with 100 kg TNT were performed on SCS sandwich specimens to investigate the key parameters that affect the blast resistance of SCS sandwich *** yield line method is proposed to predict the plastic capacity and post peak large deflection of the sandwich ***,an energy balanced model is developed to analyze the global behavior of SCS sandwich panels subj.cted to dynamic load.

关键词： blast load composite structure impact load lightweight concrete sandwich plate j.hook connector