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Lipid lowering in patients 75 years and older

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World Journal of Cardiology 2021年第10期13卷 526-532页

作者： Umidakhon Makhmudova P Christian Schulze Harry r.davis Oliver Weingartner Klinik fur Innere Medizin I Universitatsklinikum JenaJena 07747Germany Synergy Partners rD Solutions Synergy Partners RD SolutionsGaithersburgMD 20850United States

More than twenty years ago,knowledge about the importance of cholesterol absorption and the potential therapeutic effect of its inhibition led to the discovery and clinical application of the first and only cholesterol absorption inhibitor to date–*** then,ezetimibe has become a well-recognized player in lipid-lowering *** findings of IMPrOVE-IT and EWTOPIA 75 imply that elderly patients over the age of 75 years in particular benefit from *** review summarizes the evidence,discusses the possible underlying pathophysiological mechanisms and calls for a change in future dyslipidemia guidelines.

关键词： Cholesterol Cholesterol absorption Cholesterol synthesis Ezetimibe Elderly

Physical and chemical processes promoting dominance of the toxic cyanobacterium Cylindrospermopsis raciborskii

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Chinese Journal of Oceanology and Limnology 2011年第4期29卷 883-891页

作者： Michele A. BUrFOrD Timothy W. davis Australian rivers Institute Griffith University Nathan Qld. 4111 Australia

The freshwater cyanobacterium, Cylindrospermopsis raciborskii （Woloszyflska） Seenayya and Subba raju is a common species in lakes and reservoirs globally. In some areas of the world it can produce cytoand hepatotoxins （cylindrospermopsins, saxitoxins）, making blooms of this species a serious health concern for humans. In the last 10 15 years, there has been a considerable body of research conducted on the ecology, physiology and toxin production of this species and this paper reviews these studies with a focus on the cylindrospermopsin （CYN）-producing strains. C. raciborskii has low light requirements, close to neutral buoyancy, and a wide temperature tolerance, giving it the capacity to grow in many lentic waterbodies. It also has a flexible strategy with respect to nitrogen （N） utilisation; being able to switch between utilising fixed and atmospheric N as sources of N fluctuate. Additionally this species has a high phosphate （DIP） affinity and storage capacity. Like many cyanobacteria, it also has the capacity to use dissolved organic phosphorus （DOP）. Changes in nutrient concentrations, light levels and temperature have also been found to affect production of the toxin CYN by this species. However, optimal toxin production does not necessarily occur when growth rates are optimal. Additionally, different strains of C. raciborskii vary in their cell quota of CYN, making it difficult to predict toxin concentrations, based on C. raciborskii cell densities. In summary, the ecological flexibility of this organism means that controlling blooms of C. raciborskii is a difficult undertaking. However, improved understanding of factors promoting the species and toxin production by genetically capable strains will lead to improved predictive models of blooms.

关键词： cyanobacteria freshwater algal toxins nutrients light temperature

Supersonic Transport redux？

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Engineering 2017年第6期3卷 785-786页

作者： Lance A. davis Senior Advisor US National Academy of Engineering

On June 26, 2017, the US National Aeronautics and Space Administration （NASA） announced that it had completed a preliminary design review （PDr） for its Quiet Supersonic Transport （QueSST）, designed with the pros... 详细信息

关键词： CCS 可再生能源发电

The Shale Oil and Gas revolution

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Engineering 2018年第4期4卷 438-439页

作者： Lance A. davis Senior Advisor US National Academy of Engineering USA

The global energy landscape has very often been subject to upheaval due to geopolitical strife. Americans old enough will vividly recall waiting in long lines at gasoline stations during the 1973 oil embargo. At present, there is another sort of upheaval afoot that is totally driven by technology-hydraulic fracturing and horizontal drilling.

关键词：水平钻井技术水力压裂石油化工行业技术创新

Functionalized, carbon nanotube material for the catalytic degradation of organophosphate nerve agents

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Nano research 2014年第3期7卷 390-398页

作者： Mark M. Bailey John M. Heddleston Jeffrey davis Jessica L. Staymates Angela r. Hight Walker National Institute of Standards and Technology (NIST) Semiconductor and Dimensional Metrology Division Gaithersburg MD USA National Institute of Standards and Technology (NIST) Materials Measurement Science Division Gaithersburg MD USA Present Address: United States Army Medical research Institute of Infectious Diseases (USAMrIID) Center for Aerobiological Sciences Fort Detrick MD USA

recent world events have emphasized the need to develop innovative, functional materials that will safely neutralize chemical warfare （CW） agents in situ to protect military personnel and civilians from dermal exposure. Here, we demonstrate the efficacy of a novel, proof-of-concept design for a Cu-containing catalyst, chemically bonded to a single-wall carbon nanotube （SWCNT） structural support, to effectively degrade an organophosphate simulant. SWCNTs have high tensile strength and are flexible and light-weight, which make them a desirable structural component for unique, fabric-like materials. This study aims to develop a self-decontaminating, carbon nanotube-derived material that can ultimately be incorporated into a wearable fabric or protective material to minimize dermal exposure to organophosphate nerve agents and to prevent accidental exposure during decontamination procedures. Carboxylated SWCNTs were functionalized with a polymer, which contained Cu-chelating bipyridine groups, and their catalytic activity against an organophosphate simulant was measured over time. The catalytically active, functionalized nanomaterial was characterized using X-ray fluorescence and raman spectroscopy. Assuming zeroth-order reaction kinetics, the hydrolysis rate of the organophosphate simulant, as monitored by UV-vis absorption in the presence of the catalytically active nanomaterial, was 63 times faster than the uncatalyzed hydrolysis rate for a sample containing only carboxylated SWCNTs or a control sample containing no added nanotube materials.

关键词： single-wall carbonnanotubefunctionalization catalytically-activenanomaterial chemical warfare agent

An evaluation of a catch and release trout regulation in rapid Creek,South Dakota

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Aquaculture and Fisheries 2023年第5期8卷 558-563页

作者： Jacob L.davis South Dakota Department of Game Fish and Parks4130 Adventure TrailRapid CitySD57702USA

Often,catch and release regulations are meant to maximize a fisheries potential to create trophy fish.I evaluated adult Brown Trout populations at five locations within rapid Creek within rapid City,SD over a two-year *** each year,one of these locations was within a catch and release area,while two were *** 2012,density and biomass estimates were higher in a site located outside of the catch and release ***,size structure within the catch and release area was only significantly larger than one of the two sites outside of the regulation *** relative weight values were inversely related to density estimates,with the lowest density sites having the highest mean relative ***,a site outside of the catch and release area had the highest abundance and biomass estimates in *** cumulative length distribution was significantly different between the site within the catch and release area and the two located *** weight was significantly higher in the catch and release area than the two sites *** population characteristics within the catch and release area were not consistently better than outside,it is more likely that factors such as habitat and density dependence are impacting the Brown Trout population more than the regulation itself.

关键词： Trout regulations Catch and release

Variability of waste copper slag concrete and its effect on the seismic safety of reinforced concrete building: A case study

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Frontiers of Structural and Civil Engineering 2022年第1期16卷 117-130页

作者： Swetapadma PANDA Nikhil P.ZADE Pradip SArKAr robin davis Department of Civil Engineering Institute of Technical Education and ResearchOdisha 751030India Department of Civil Engineering National Institute of Technology RourkelaOdisha 769008India Department of Civil Engineering National Institute of Technology CalicutKerala 673601India

Proven research output on the behavior of structures made of waste copper slag concrete can improve its utilization in the construction industry and thereby help to develop a sustainable built *** numerous studies on waste copper slag concrete can be found in the published literature,no research has focused on the structural application of this type of *** particular,the variability in the strength properties of waste copper slag concrete,which is required for various structural applications,such as limit state design formulation,reliability-based structural analysis,etc.,has so far not attracted the attention of *** paper quantifies the uncertainty associated with the compressive-,flexural-and split tensile strength of hardened concrete with different dosages of waste copper slag as fine ***-fit probability distribution models are proposed based on statistical analyses of strength data generated from laboratory *** addition,the paper presents a reliability-based seismic risk assessment of a typical waste copper slag incorporated reinforced concrete framed building,considering the proposed distribution *** results show that waste copper slag can be safely used for seismic resistant structures as it results in an identical probability of failure and dispersion in the drift demand when compared with a conventional concrete building made of natural sand.

关键词： waste copper slag quantification of variability goodness-of-fit test seismic risk assessment PSDM

Parallelization of an Implicit Algorithm for Multi-Dimensional Particle-in-Cell Simulations

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Communications in Computational Physics 2014年第8期16卷 599-611页

作者： George M.Petrov Jack davis Naval research Laboratory Plasma Physics Division4555 Overlook Ave.SWWashingtonDC 20375USA.

The implicit 2D3V particle-in-cell(PIC)code developed to study the interaction of ultrashort pulse lasers with matter[*** and ***,Computer ***.179,868(2008);*** 18,073102(2011)]has been parallelized using MPI(Message Passing Interface).The parallelization strategy is optimized for a small number of computer cores,up to about *** on the algorithm implementation are given with emphasis on code optimization by overlapping computations with *** evaluation for 1D domain decomposition has been made on a small Linux cluster with 64 computer cores for two typical regimes of PIC operation:”particle dominated”,for which the bulk of the computation time is spent on pushing particles,and”field dominated”,for which computing the fields is *** a small number of computer cores,less than 32,the MPI implementation offers a significant numerical *** the”particle dominated”regime it is close to the maximum theoretical one,while in the”field dominated”regime it is about 75-80%of the maximum *** a number of cores exceeding 32,performance degradation takes place as a result of the adopted 1D domain *** code parallelization will allow future implementation of atomic physics and extension to three dimensions.

关键词： Particle-in-cell Maxwell equations MPI lasertarget interaction.

Spon's Landscape and External Works Price Book 2005: Free CDrOM (Spons Price Books) 24

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