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ANALYSIS OF SINGLE PANE WINDOW REPLACEMENT

Journal of Green Building 2014年第3期9卷 50-59页

作者： Dr.Paul T.Daniell andrew grimm Department of Petroleum Engineering Marietta CollegeMariettaOH.

An engineering and economic analysis of energy loss through single paned windows in a large college building is *** goal of this work was to determine an economically viable solution for Marietta College to save on energy *** on the model presented,the economics of double paned window installation are *** alternative solution employing the addition of storm windows to the existing single paned windows has yielded very exciting *** double paned windows are generally the first thought when it comes to energy efficient windows,this work shows that storm window addition yields a much lower investment and quicker payback period for this specific *** engineering analysis and experimental technique presented can be used to investigate the cost benefit of single paned window upgrades for other buildings.

关键词： energy savings single pane windows conduction convection

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Campylobacter concisus and inflammatory bowel disease

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World Journal of Gastroenterology 2014年第5期20卷 1259-1267页

作者： Li Zhang Hoyul Lee Michael C grimm Stephen M Riordan andrew S Day Daniel A Lemberg School of Biotechnology and Biomo-lecular Sciences University of New South Wales St George and Sutherland Clinical School University of New South Wales Gastrointestinal and Liver Unit The Prince of Wales Hospital Prince of Wales Clinical School University of New South Wales Department of Gastroenter-ology Sydney Children’s Hospital Department of Pediatrics University of Otago Christchurch School of Women’s and Children’s Health University of New South Wales

Investigation of the possible role of Campylobacter concisus(C. concisus) in inflammatory bowel disease(IBD) is an emerging research area. Despite the association found between C. concisus and IBD, it has been difficult to explain how C. concisus, a bacterium that is commonly present in the human oral cavity, may contribute to the development of enteric diseases. The evidence presented in this review shows that some C. concisus strains in the oral cavity acquired zonula occludens toxin(zot) gene from a virus(prophage) and that C. concisus Zot shares conserved motifs with both Vibrio cholerae Zot receptor binding domain and human zonulin receptor binding domain. Both Vibrio cholerae Zot and human zonulin are known to increase intestinal permeability by affecting the tight junctions. Increased intestinal permeability is a feature of IBD. Based on these data, we propose that a primary barrier function defect caused by C. concisus Zot is a mechanism by which zot-positive C. concisus strains may trigger the onset and relapse of IBD.

关键词： Campylobacter concisus Inflammatory bowel disease Zonula occludens toxin Tight junctions Intestinal permeability

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