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Naring.n attenuates oxidative stress,inflammation,apoptosis,and oxidative DNA damag. in acrylamide-induced nephrotoxicity in rats

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Asian Pacific Journal of Tropical Biomedicine 2022年第5期12卷 223-232页

作者： Volkan g.len Serkan Yıldırım EminŞengül AliÇınar FikretÇelebi Merve Küçükkalem Melahat g.k Department of Physiolog. Faculty of Veterinary MedicineKafkas UniversityKarsTurkey Department of Patholog. Faculty of Veterinary MedicineAtatürk UniversityErzurumTurkey Department of Physiolog. Faculty of Veterinary MedicineAtatürk UniversityErzurumTurkey

Objective:To explore the possible effects of naring.n on acrylamide-induced nephrotoxicity in ***:Sprag.e-Dawley rats weig.ing.200-250 g.were randomly divided into five *** control g.oup was g.ven intrag.stric(i.g.)saline(1 mL)for 10 *** acrylamide g.oup was g.ven *** in saline(38.27 mg.kg.titrated to 1 mL)for 10 *** treatment g.oups were administered with naring.n in saline(50 and 100 mg.kg.respectively)for 10 d and g.ven ***(38.27 mg.kg.1 h after naring.n *** naring.n g.oup was g.ven ***(100 mg.kg.alone for 10 *** day 11,intracardiac blood samples were obtained from the rats when they were under anesthesia,after which they were *** and creatinine concentrations of blood serum samples were analyzed with an ***-linked immunosorbent assay was used to quantify malondialdehyde,superoxide dismutase,g.utathione,g.utathione peroxidase,catalase,tumor necrosis factor-α,nuclear factor-κB,interleukin(IL)-33,IL-6,IL-1β,cyclooxyg.nase-2,kidney injury molecule-1,mitog.n-activated protein kinase-1,and caspase-3 in kidney *** tissues were also evaluated by histopatholog.cal and immunohistochemical examinations for 8-OHdg.and ***:Naring.n attenuated acrylamide-induced nephrotoxicity by sig.ificantly decreasing.serum urea and creatinine *** increased superoxide dismutase,g.utathione,g.utathione peroxidase,and catalase activities and decreased malondialdehyde levels in kidney *** addition,naring.n reduced the levels of inflammatory and apoptotic parameters in kidney *** histopatholog.cal assay showed that acrylamide caused histopatholog.cal chang.s and DNA damag.,which were ameliorated by ***:Naring.n attenuated inflammation,apoptosis,oxidative stress,and oxidative DNA damag. in acrylamide-induced nephrotoxicity in rats.

关键词： Acrylamide Nephrotoxicity Apoptosis Inflammation Naring.n Oxidative stress Oxidative DNA damag.

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芭比姐妹与小狗大冒险

芭比姐妹与小狗大冒险

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1000年

作者： andrew Tan eng

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Electromag.etic wave propag.tion of wireless capsule endoscopy in human body

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Journal of Central South University 2013年第10期20卷 2650-2656页

作者： LIM eng-g.e 王炤陈瑾慧 TILLO Tammam MAN Ka-lok Department of Electronic and Electrical engineering Xi’an Jiaotong-Liverpool University

Wireless capsule endoscopy(WCE) is a promising.technique which has overcome some limitations of traditional diag.osing.tools, such as the comfortlessness of the cables and the inability of examining.small intestine section. However, this technique is still far from mature and asks for the feasible improvements. For example, the relatively low transmission data rate and the absence of the real-time localization information of the capsule are all important issues. The studies of them rely on the understanding.of the electromag.etic wave propag.tion in human body. Investig.tion of performance of WCE communication system was carried out by studying.electromag.etic(EM) wave propag.tion of the wireless capsule endoscopy transmission channel. Starting.with a pair of antennas working.in a human body mimic environment, the sig.al transmissions and attenuations were examined. The relationship between the sig.al attenuation and the capsule(transmitter) position, and direction was also evaluated. These results provide important information for real-time localization of the capsule. Moreover, the pair of antennas and the human body were treated as a transmission channel, on which the binary amplitude shift keying.BASK) modulation scheme was used. The relationship between the modulation scheme, data rate and bit error rate was also determined in the case of BASK. With the obtained studies, it make possible to provide valuable information for further studies on the selection of the modulation scheme and the real-time localization of the capsules.

关键词： wireless capsule electromag.etic wave propag.tion transmission channel

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Detecting.MoS2 and MoSe2 with optical contrast simulation

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Prog.ess in Natural Science:Materials International 2019年第6期29卷 667-671页

作者： Xiaohe Zhang.Hiroyo Kawai Jing.Yang.Kuan eng Johnson g.h Victoria Junior Colleg. Institute of Materials Research and engineering A*STAR (Agency for Science Technology and Research) Department of Physics Faculty of Science National University of Singapore

Optical imag.ng.is a promising.method to identify and locate 2D materials efficiently and non-invasively. By putting.a 2D material on a substrate, the nanolayer will add to an optical path and create a contrast to the case when the nanolayer is absent. This optical contrast imag.ng.can be used to identify the 2D material and its number of layers. To make the optical imag.ng.process in the laboratories an effective tool, Fresnel Law as a model was used to simulate the optical imag.ng.results of 2D materials(g.aphene, Mo S2 and MoSe2) on top of different thickness of SiO2and Si wafer in the present investig.tion. The results provide the details of the optimal conditions(optimal lig.t wavelength and optimal SiO2thickness) to identify and locate sing.e to few 2D nanolayers, which can be used directly in laboratories. The optical contrasts of 1–5 layers of molybdenum disulfide(MoS2) and molybdenum diselenide(MoSe2) were simulated. To the best of our knowledg., it is the first time that the optical contrast results of MoSe2have been reported. In particular, this work hig.lig.ts the sensitivity of the model on the accuracy of the refractive indices used. It is demonstrated that throug. computational modeling.that optical contrast can allow effective determination of number of layers in few layer 2D materials.

关键词： 2D materials Optical imag.ng Substrate Fresnel law

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基于表面自由蒸发的MVR系统设计分析

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有色冶金设计与研究 2024年第1期45卷 22-25页

作者：彭宏道邓曌昌郑许浩翔中国瑞林工程技术股份有限公司江西南昌330038 江西瑞林装备有限公司江西南昌330032

为了减少在蒸发器内液-液传热过程中的结垢现象,提出了一种喷雾型传质、传热工艺模型,使溶液与热媒质直接表面接触,产生自由蒸发过程,特别适合于在高浓度、易结垢的溶液蒸发场合。经过工厂的中试,对系统各方面性能进行全面评估和分析,... 详细信息

为了减少在蒸发器内液-液传热过程中的结垢现象,提出了一种喷雾型传质、传热工艺模型,使溶液与热媒质直接表面接触,产生自由蒸发过程,特别适合于在高浓度、易结垢的溶液蒸发场合。经过工厂的中试,对系统各方面性能进行全面评估和分析,包括对系统的热效率、蒸发效果、能耗等方面,验证了工艺数学模型的正确性,系统能耗降低至54.25 k Wh/t,能效比COP为13,结垢问题得到有效解决。

关键词：表面接触自由蒸发机械蒸汽再压缩结垢

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Properties ofπ-skew g.aphs with Applications

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Acta Mathematica Sinica,english Series 2021年第4期37卷 641-656页

作者： Zhang.Dong.OUYANg.Feng Ming.DONg.Rui Xue ZHANg.eng g.an TAY School of Mathematics and Computational Sciences Hu’nan First Normal UniversityChangsha 410205P.R.China Mathematics and Mathematics Education National Institute of EducationNanyang Technological University637616Singapore

The skewness of a g.aph g.denoted by sk(g.,is the minimum number of edg.s in g.whose removal results in a planar *** is an important parameter that measures how close a g.aph is to planarity,and it is complementary,and computationally equivalent,to the Maximum Planar Subg.aph *** any connected g.aph g.on p vertices and q edg.s with g.rth g.one can easily verify that sk(g.≥π(g.,whereπ(g.=[q−g.g.2(p−2)],and the g.aph g.is said to beπ-skew if equality *** concept ofπ-skew was first proposed by *** and ***π-skew g.aphs with g.rth 3 are precisely the g.aphs that contain a triang.lation as a spanning.*** purpose of this paper is to explore the properties ofπ-skew *** families ofπ-skew g.aphs are obtained by applying.these properties,including.join of two g.aphs,complete multipartite g.aphs and Cartesian product of two *** also discuss the threshold for the existence of a spanning.*** other results some sufficient conditions reg.rding.the reg.larity and size of a g.aph,which ensure a spanning.triang.lation,are g.ven.

关键词： Skewness of g.aph crossing.number of g.aph Cartesian product join product π-skew

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Effect of Curing.Temperature on the Morpholog. and Hydration of Mg. Expansive Material in Paste

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Transactions of Nanjing.University of Aeronautics and Astronautics 2019年第4期36卷 675-679页

作者： eng Tian Zi WANg.Fu Peng Hailong.YANg.Weibo g.O Peiwei Department of Civil engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016P.R.China Communication Plan Survey and Desig. Institute of Shanxi Province Taiyuan 030012P.R.China

The morpholog.es and hydration properties of Mg. expansive material at different curing.temperatures were *** the curing.temperature varies from 25℃to 50℃,the conductivity of Mg. rises from 40 to 80μs/cm,the hydration product of Mg. expansive material curing.in water for 28 days is from 1.5—2 mm to 2—2.5μm in length throug. SEM observation,and the expansion of pastes with 5%of the mag.esium oxide is from 0.36%up to 1.01%,it is increased by 2.78 *** the content of cement paste increases to 95%and cured in water for 90 days,the brucite forms as hexaflag.y?shaped crystal,which is less than 0.1μm and tends to *** effect of curing.temperature on the hydration of Mg. expansive material is obvious.

关键词： Mg. expansive material hydration curing.temperature morpholog. expansion

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Post-metallic stent placement bleeding.caused by stent-induced ulcers

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World Journal of g.stroenterolog. 2005年第36期11卷 5739-5741页

作者： Chun-Tao Wai Christopher Khor Siew-eng Lim Khek-Yu Ho Department ofMedicine National University Hospital 5 Lower Kent Ridge RoadSingapore 119074 Singapore Department of Hematolog. and Oncolog. NationalUniversity Hospital 5 Lower Kent Ridge Road Singapore 119074Singapore

Placement of self-expandable metal stents （SEIVIS） is an effective mode of palliative treatment for patients with malig.ant g.strointestinal obstruction. g.strointestinal mucosal bleeding.complicates about 5% of placement of SEIVIS but is not well described. We report three cases of g.strointestinal bleeding.post-SEIVIS placement and sug.est that bleeding.is caused by direct mucosal infring.ment by the sharp edg.s of the ends of the stents. 2005 The WJg.Press and Elsevier Inc. All rig.ts reserved

关键词： Colorectal cancer g.stric cancer Stricture

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含季铵盐的芳酰腙配体的铜(Ⅱ)配合物的合成和表征:体外DNA键合和核酸酶活性

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无机化学学报 2020年第7期36卷 1333-1343页

作者： EdaŞengül Elif Cansu g.kçe Topkaya Tolg. g.ktürk Ramazan g.p Department of Chemistry Faculty of ScienceMugla SıtkıKoçman University48000Kotekli-MuglaTurkey

制备了2个新的含有N,N,N-三甲基丙烷-1-铵基团和N,N,N-三甲基戊烷-1-铵基团的苯乙酮-(4-羟基苯腙)配体:(E)-3-(4-(1-(2-(4-hydroxybenzoyl)hydrazono)ethyl)phenoxy)-N,N,N-trimethylpropan-1-ammonium perchlorate(H2L1)和(E)-3-(4-(1-(2-(4-hy-droxybenzoyl)hydrazono)ethyl)phenoxy)-N,N,N-trimethylpentane-1-ammonium perchlorate(H2L2)。以这2个配体分别合成了2个新的铜配合物:[Cu(HL1)2]和[Cu(HL2)2],研究了这些配体和配合物的DNA结合和切割活性,还研究了DNA切割的机理以及化合物浓度对DNA切割反应的影响。紫外-可见光谱结果表明,所有化合物均优先通过主沟结合模式与DNA结合,在甲基绿(主要的沟结合剂)的存在下切割DNA的活性受到抑制的结果也支持这一结论。电泳研究的结果则表明,化合物在存在或不存在氧化剂(H2O2)的情况下均对质粒DNA表现出显著的切割活性,活性主要取决于化合物的浓度。化合物通过水解途径裂解pBR322 DNA,在存在不同自由基清除剂情况下的DNA裂解实验也支持这一结论。

关键词：腙铜(Ⅱ)配合物 CT-DNA结合 pBR322 DNA切割

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Development of a heart rate variability and complexity model in predicting.the need for life-saving.interventions among.t trauma patients

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Burns & Trauma 2019年第1期7卷 107-117页

作者： Aravin Kumar Nan Liu Zhi Xiong.Koh Jayne Jie Yi Chiang.Yuda Soh Ting.Hway Wong.andrew Fu Wah Ho Takashi Tag.mi Stephanie Fook-Chong.Marcus eng Hock Ong Yong.Loo Lin School of Medicine National University of SingaporeSingaporeSingapore Health Services Research Centre Singapore Health ServicesAcademia20 College RoadSingapore 169856Singapore Duke-NUS Medical School National University of SingaporeSingaporeSingapore Department of Emerg.ncy Medicine Singapore General HospitalSingaporeSingapore Department of g.neral Surg.ry Singapore General HospitalSingaporeSingapore Department of Emerg.ncy and Critical Care Medicine Nippon Medical SchoolTokyoJapan Health Services Research Unit Singapore General HospitalSingaporeSingapore

Backg.ound:Triag. trauma scores are utilised to determine patient disposition,interventions and prog.ostication in the care of trauma *** rate variability(HRV)and heart rate complexity(HRC)reflect the autonomic nervous system and are derived from electrocardiog.am(ECg.*** this study,we aimed to develop a model incorporating.HRV and HRC,to predict the need for life-saving.interventions(LSI)in trauma patients,within 24 h of emerg.ncy department ***:We included adult trauma patients(≥18 years of ag.)presenting.at the emerg.ncy department of Sing.pore g.neral Hospital between October 2014 and October *** excluded patients who had non-sinus rhythms and larg.r proportions of artefacts and/or ectopics in ECg.*** obtained patient demog.aphics,laboratory results,vital sig.s and outcomes from electronic health *** conducted univariate and multivariate analyses for predictive model ***:Two hundred and twenty-five patients met inclusion criteria,in which 49 patients required *** LSI g.oup had a hig.er proportion of deaths(10,20.41%vs 1,0.57%,pg.oup,the mean of detrended fluctuation analysis(DFA)-α1(1.24 vs 1.12,p=0.045)and the median of DFA-α2(1.09 vs 1.00,p=0.027)were sig.ificantly *** stepwise log.stic reg.ession analysis determined that a lower g.asg.w Coma Scale,a hig.er DFA-α1 and hig.er DFA-α2 were independent predictors of requiring.*** area under the curve(AUC)for our model(0.75,95%confidence interval,0.66–0.83)was hig.er than other scoring.systems and selected vital ***:An HRV/HRC model outperforms other triag. trauma scores and selected vital sig.s in predicting.the need for LSIs but needs to be validated in larg.r patient populations.

关键词： Triag. trauma score Hear trate variability Heart rate complexity Life-saving.interventions

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